Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2000 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFJF |
| Texto Completo: | http://dx.doi.org/10.1590/S0004-28032000000400007 https://repositorio.ufjf.br/jspui/handle/ufjf/9175 |
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2019-02-22T13:30:17Z2019-02-212019-02-22T13:30:17Z2000-11374224226http://dx.doi.org/10.1590/S0004-28032000000400007https://repositorio.ufjf.br/jspui/handle/ufjf/9175-The authors describe the case of a young Brazilian woman who was treated of ileocolonic Crohn's disease sparing rectum, as confirmed by colonoscopy and histopathological examination. After a 4-year course of sulfasalazine treatment, she presented with skin facial lesions in vespertilio, fever, arthralgias and high titers of anti-ANA and LE cells. A sulfasalazine-induced lupus syndrome was diagnosed, because after sulfasalazine withdrawal and a short course of prednisone, the clinical symptoms disappeared and the laboratory tests returned to normal. Mesalazine 3 g/day was started and the patient remained well for the next 3 years, when she was again admitted with fever, weakness, arthralgias, diplopy, strabismus and hypoaesthesia in both hands and feet, microhematuria, haematic casts, hypocomplementemia and high titers of autoimmune antibodies. A diagnosis of associated systemic lupus erythematosus was made. Although a pulsotherapy with methylprednisolone was started, no improvement was noticed. A cyclophosphamide trial was tried and again no positive results occurred. The patient evolved to severe clinical manifestations of general vasculitis affecting the central and peripheral nervous system and lungs, having a fatal evolution after 2 weeks. Although uncommon, the association of both disease may occur, and the authors call attention to this possibility, making a brief review of literature.eng--BrasilArquivos de Gastroenterologia-Crohn diseaseLupus erythematosusSystemicFatal evolution of systemic Lupus erythematosus associated with Crohn's diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleChebli, Júlio Maria FonsecaGaburri, Pedro DuarteSouza, Aécio Flávio Meirelles deDias, Kátia Valéria BastosCimino, Karla OliveiraCarvalho-Filho, Roberto José deLucca, Fernando de Azevedoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFJFinstname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFTHUMBNAILFatal evolution of systemic Lupus erythematosus associated with Crohn's disease.pdf.jpgFatal evolution of systemic Lupus erythematosus associated with Crohn's disease.pdf.jpgGenerated Thumbnailimage/jpeg1650https://repositorio.ufjf.br/jspui/bitstream/ufjf/9175/4/Fatal%20evolution%20of%20systemic%20Lupus%20erythematosus%20associated%20with%20Crohn%27s%20disease.pdf.jpgccf613bfb2acd082110c0056218ac191MD54ORIGINALFatal evolution of systemic Lupus erythematosus associated with Crohn's disease.pdfFatal evolution of systemic Lupus erythematosus associated with Crohn's disease.pdfapplication/pdf158362https://repositorio.ufjf.br/jspui/bitstream/ufjf/9175/1/Fatal%20evolution%20of%20systemic%20Lupus%20erythematosus%20associated%20with%20Crohn%27s%20disease.pdf5b18b7578b50b7a3d90316efac8c13ccMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82197https://repositorio.ufjf.br/jspui/bitstream/ufjf/9175/2/license.txt000e18a5aee6ca21bb5811ddf55fc37bMD52TEXTFatal evolution of systemic Lupus erythematosus associated with Crohn's disease.pdf.txtFatal evolution of systemic Lupus erythematosus associated with Crohn's disease.pdf.txtExtracted texttext/plain12005https://repositorio.ufjf.br/jspui/bitstream/ufjf/9175/3/Fatal%20evolution%20of%20systemic%20Lupus%20erythematosus%20associated%20with%20Crohn%27s%20disease.pdf.txt4554856afa6bdf3377438a0ed8313855MD53ufjf/91752019-06-16 12:31:14.157oai:hermes.cpd.ufjf.br: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Repositório InstitucionalPUBhttps://repositorio.ufjf.br/oai/requestopendoar:2019-06-16T15:31:14Repositório Institucional da UFJF - Universidade Federal de Juiz de Fora (UFJF)false |
| dc.title.pt_BR.fl_str_mv |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| title |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| spellingShingle |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease Chebli, Júlio Maria Fonseca - Crohn disease Lupus erythematosus Systemic |
| title_short |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| title_full |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| title_fullStr |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| title_full_unstemmed |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| title_sort |
Fatal evolution of systemic Lupus erythematosus associated with Crohn's disease |
| author |
Chebli, Júlio Maria Fonseca |
| author_facet |
Chebli, Júlio Maria Fonseca Gaburri, Pedro Duarte Souza, Aécio Flávio Meirelles de Dias, Kátia Valéria Bastos Cimino, Karla Oliveira Carvalho-Filho, Roberto José de Lucca, Fernando de Azevedo |
| author_role |
author |
| author2 |
Gaburri, Pedro Duarte Souza, Aécio Flávio Meirelles de Dias, Kátia Valéria Bastos Cimino, Karla Oliveira Carvalho-Filho, Roberto José de Lucca, Fernando de Azevedo |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Chebli, Júlio Maria Fonseca Gaburri, Pedro Duarte Souza, Aécio Flávio Meirelles de Dias, Kátia Valéria Bastos Cimino, Karla Oliveira Carvalho-Filho, Roberto José de Lucca, Fernando de Azevedo |
| dc.subject.cnpq.fl_str_mv |
- |
| topic |
- Crohn disease Lupus erythematosus Systemic |
| dc.subject.por.fl_str_mv |
Crohn disease Lupus erythematosus Systemic |
| description |
- |
| publishDate |
2000 |
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2000-11 |
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2019-02-22T13:30:17Z |
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2019-02-21 2019-02-22T13:30:17Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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https://repositorio.ufjf.br/jspui/handle/ufjf/9175 |
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http://dx.doi.org/10.1590/S0004-28032000000400007 |
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http://dx.doi.org/10.1590/S0004-28032000000400007 https://repositorio.ufjf.br/jspui/handle/ufjf/9175 |
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eng |
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Arquivos de Gastroenterologia |
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Brasil |
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