Probing the uterine microenvironment through Systems Biology approaches

Detalhes bibliográficos
Autor(a) principal: Mesquita, F. S.
Data de Publicação: 2012
Outros Autores: D’Alexandri, F. L., Scolari, S. C., Membrive, C. M. B., Papa, P. C., Cardoso, D., Martin, I., Sales, J. N. S., Wheelock, C. E., Eberlin, M. N., Binelli, M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFLA
Texto Completo: http://repositorio.ufla.br/jspui/handle/1/38523
Resumo: In cattle, the developing preimplantation conceptus depends solely on its surrounding environment for supplying nutrients and growth stimuli. Also, throughout gestation, it is during the preimplantation stage of gestation that most conceptus mortality is observed. Thus, one could rationalize that the composition of the uterine environment plays a major role on conceptus survival. However, the biochemical composition of the uterine environment is only just starting to be deciphered and conditions associated with optimal conceptus development are virtually unknown. In this review we attempt to briefly review and discuss issues associated with sampling and analyzing the uterine environment. We suggest that modern, holistic approaches such as Systems Biology are necessary to characterize the uterine functions associated with pregnancy success in cattle.
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spelling Probing the uterine microenvironment through Systems Biology approachesEndometrial biopsyHistotrophSystems biologyUterine flushingUterine receptivityBiópsia endometrialHistotrophBiologia de sistemasIn cattle, the developing preimplantation conceptus depends solely on its surrounding environment for supplying nutrients and growth stimuli. Also, throughout gestation, it is during the preimplantation stage of gestation that most conceptus mortality is observed. Thus, one could rationalize that the composition of the uterine environment plays a major role on conceptus survival. However, the biochemical composition of the uterine environment is only just starting to be deciphered and conditions associated with optimal conceptus development are virtually unknown. In this review we attempt to briefly review and discuss issues associated with sampling and analyzing the uterine environment. We suggest that modern, holistic approaches such as Systems Biology are necessary to characterize the uterine functions associated with pregnancy success in cattle.Brazilian College of Animal Reproduction2020-01-16T11:39:36Z2020-01-16T11:39:36Z2012-10info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMESQUITA, F. S. et al. Probing the uterine microenvironment through Systems Biology approaches. Animal Reproduction, Belo Horizonte, v. 9, n. 4, p. 713-722, Oct./Dec. 2012.http://repositorio.ufla.br/jspui/handle/1/38523Animal Reproductionreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessMesquita, F. S.D’Alexandri, F. L.Scolari, S. C.Membrive, C. M. B.Papa, P. C.Cardoso, D.Martin, I.Sales, J. N. S.Wheelock, C. E.Eberlin, M. N.Binelli, M.eng2020-01-16T12:01:53Zoai:localhost:1/38523Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2020-01-16T12:01:53Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false
dc.title.none.fl_str_mv Probing the uterine microenvironment through Systems Biology approaches
title Probing the uterine microenvironment through Systems Biology approaches
spellingShingle Probing the uterine microenvironment through Systems Biology approaches
Mesquita, F. S.
Endometrial biopsy
Histotroph
Systems biology
Uterine flushing
Uterine receptivity
Biópsia endometrial
Histotroph
Biologia de sistemas
title_short Probing the uterine microenvironment through Systems Biology approaches
title_full Probing the uterine microenvironment through Systems Biology approaches
title_fullStr Probing the uterine microenvironment through Systems Biology approaches
title_full_unstemmed Probing the uterine microenvironment through Systems Biology approaches
title_sort Probing the uterine microenvironment through Systems Biology approaches
author Mesquita, F. S.
author_facet Mesquita, F. S.
D’Alexandri, F. L.
Scolari, S. C.
Membrive, C. M. B.
Papa, P. C.
Cardoso, D.
Martin, I.
Sales, J. N. S.
Wheelock, C. E.
Eberlin, M. N.
Binelli, M.
author_role author
author2 D’Alexandri, F. L.
Scolari, S. C.
Membrive, C. M. B.
Papa, P. C.
Cardoso, D.
Martin, I.
Sales, J. N. S.
Wheelock, C. E.
Eberlin, M. N.
Binelli, M.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mesquita, F. S.
D’Alexandri, F. L.
Scolari, S. C.
Membrive, C. M. B.
Papa, P. C.
Cardoso, D.
Martin, I.
Sales, J. N. S.
Wheelock, C. E.
Eberlin, M. N.
Binelli, M.
dc.subject.por.fl_str_mv Endometrial biopsy
Histotroph
Systems biology
Uterine flushing
Uterine receptivity
Biópsia endometrial
Histotroph
Biologia de sistemas
topic Endometrial biopsy
Histotroph
Systems biology
Uterine flushing
Uterine receptivity
Biópsia endometrial
Histotroph
Biologia de sistemas
description In cattle, the developing preimplantation conceptus depends solely on its surrounding environment for supplying nutrients and growth stimuli. Also, throughout gestation, it is during the preimplantation stage of gestation that most conceptus mortality is observed. Thus, one could rationalize that the composition of the uterine environment plays a major role on conceptus survival. However, the biochemical composition of the uterine environment is only just starting to be deciphered and conditions associated with optimal conceptus development are virtually unknown. In this review we attempt to briefly review and discuss issues associated with sampling and analyzing the uterine environment. We suggest that modern, holistic approaches such as Systems Biology are necessary to characterize the uterine functions associated with pregnancy success in cattle.
publishDate 2012
dc.date.none.fl_str_mv 2012-10
2020-01-16T11:39:36Z
2020-01-16T11:39:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv MESQUITA, F. S. et al. Probing the uterine microenvironment through Systems Biology approaches. Animal Reproduction, Belo Horizonte, v. 9, n. 4, p. 713-722, Oct./Dec. 2012.
http://repositorio.ufla.br/jspui/handle/1/38523
identifier_str_mv MESQUITA, F. S. et al. Probing the uterine microenvironment through Systems Biology approaches. Animal Reproduction, Belo Horizonte, v. 9, n. 4, p. 713-722, Oct./Dec. 2012.
url http://repositorio.ufla.br/jspui/handle/1/38523
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Brazilian College of Animal Reproduction
publisher.none.fl_str_mv Brazilian College of Animal Reproduction
dc.source.none.fl_str_mv Animal Reproduction
reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
repository.name.fl_str_mv Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)
repository.mail.fl_str_mv nivaldo@ufla.br || repositorio.biblioteca@ufla.br
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