Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón

Detalhes bibliográficos
Autor(a) principal: João, Andrea Ferreira
Data de Publicação: 2015
Outros Autores: Vargas, Alexis Caniuqueo, Mosqueira, Claudio Hernández, Silva, Sandro Fernandes da, Izquierdo, Mikel, Mella, Hector Silva, Ramirez-Campillo, Rodrigo, Fernandes Filho, José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFLA
Texto Completo: http://repositorio.ufla.br/jspui/handle/1/45796
Resumo: In the field of competitive sport, genetics has gained a fundamental role in the study of sport performance. The aim of this study was to analyze the prevalence of polymorphisms R577X and insertion/deletion (I/D), occurring in a-actinin-3 (ACTN3) and angiotensin converting enzyme (ACE) genes, respectively, in Brazilian and Japanese gymnasts. A suitable non-probabilistic sample of 73 gymnasts (14 from Japan) was recruited and signed an informed consent. To measure ACTN3 and ECA saliva samples were obtained by means of real time polymerase chain reaction (iQ5 Thermal Cycler, BioRad). A high prevalence of RX ACTN3 genotype, R allele, ACE I/D genotype, and D allele were observed in Brazilian and Japanese gymnasts. In conclusion a high prevalence of RX ACTN3 genotype, R allele and ACE I/D genotype would allow a genetic advantage regarding muscle strength and power, possibly facilitating competitive success in gymnastics.
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spelling Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y JapónGene polymorphism ACTN3 and ACE in selected gymnasts athletes in Brazil and JapanPolimorfismoA-actinina 3Enzima convertidora de angiotensinaRendimiento deportivoPolymorphismA-actinin-3Angiotensin converting enzymeSport performanceIn the field of competitive sport, genetics has gained a fundamental role in the study of sport performance. The aim of this study was to analyze the prevalence of polymorphisms R577X and insertion/deletion (I/D), occurring in a-actinin-3 (ACTN3) and angiotensin converting enzyme (ACE) genes, respectively, in Brazilian and Japanese gymnasts. A suitable non-probabilistic sample of 73 gymnasts (14 from Japan) was recruited and signed an informed consent. To measure ACTN3 and ECA saliva samples were obtained by means of real time polymerase chain reaction (iQ5 Thermal Cycler, BioRad). A high prevalence of RX ACTN3 genotype, R allele, ACE I/D genotype, and D allele were observed in Brazilian and Japanese gymnasts. In conclusion a high prevalence of RX ACTN3 genotype, R allele and ACE I/D genotype would allow a genetic advantage regarding muscle strength and power, possibly facilitating competitive success in gymnastics.En el rendimiento deportivo, el estudio de la genética ha cobrado un papel fundamental al momento de estudiar el rendimiento deportivo. El objetivo del estudio fue analizar la frecuencia de genotipo y alelo de a-actinina 3 (ACTN3) R577X y enzima convertidora de angiotensina (ECA) I/D polimorfismo en un grupo de gimnastas de Brasil y Japón. Se considero una muestra de 73 gimnastas (14 de Japón y 59 de Brasil), todos los sujetos firmaron de consentimiento informado. Para la obtención de ACTN3 y ECA se recogió una muestra la saliva y analizaron los genotipos mediante el empleo de cadena de la polimerasa en tiempo real a partir del iQ5 Thermal Cycler, BioRad. Los resultados muestran una prevalencia del genotipo RX ACTN3, prevalencia del alelo R, prevalencia del genotipo DI ECA y prevalencia de alelo D en el total del grupo. Se concluye que el predominio RX del ACTN3, prevalencia del alelo R y predominio del genotipo DI en ECA pueden ofrecer una ventaja genética en cuanto a niveles de fuerza y potencia muscular, posiblemente facilitando la práctica y el éxito competitivo en gimnastas.Sociedad Chilena de Anatomía2020-12-08T00:42:23Z2020-12-08T00:42:23Z2015-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfJOÃO, A. F. et al. Polimorfismo del Gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón. International Journal of Morphology, Temuco, v. 33, n. 1, p. 262-266, marzo 2015. DOI: 10.4067/S0717-95022015000100041.http://repositorio.ufla.br/jspui/handle/1/45796International Journal of Morphologyreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessJoão, Andrea FerreiraVargas, Alexis CaniuqueoMosqueira, Claudio HernándezSilva, Sandro Fernandes daIzquierdo, MikelMella, Hector SilvaRamirez-Campillo, RodrigoFernandes Filho, Joséeng2023-05-02T11:07:32Zoai:localhost:1/45796Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2023-05-02T11:07:32Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false
dc.title.none.fl_str_mv Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
Gene polymorphism ACTN3 and ACE in selected gymnasts athletes in Brazil and Japan
title Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
spellingShingle Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
João, Andrea Ferreira
Polimorfismo
A-actinina 3
Enzima convertidora de angiotensina
Rendimiento deportivo
Polymorphism
A-actinin-3
Angiotensin converting enzyme
Sport performance
title_short Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
title_full Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
title_fullStr Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
title_full_unstemmed Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
title_sort Polimorfismo del gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón
author João, Andrea Ferreira
author_facet João, Andrea Ferreira
Vargas, Alexis Caniuqueo
Mosqueira, Claudio Hernández
Silva, Sandro Fernandes da
Izquierdo, Mikel
Mella, Hector Silva
Ramirez-Campillo, Rodrigo
Fernandes Filho, José
author_role author
author2 Vargas, Alexis Caniuqueo
Mosqueira, Claudio Hernández
Silva, Sandro Fernandes da
Izquierdo, Mikel
Mella, Hector Silva
Ramirez-Campillo, Rodrigo
Fernandes Filho, José
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv João, Andrea Ferreira
Vargas, Alexis Caniuqueo
Mosqueira, Claudio Hernández
Silva, Sandro Fernandes da
Izquierdo, Mikel
Mella, Hector Silva
Ramirez-Campillo, Rodrigo
Fernandes Filho, José
dc.subject.por.fl_str_mv Polimorfismo
A-actinina 3
Enzima convertidora de angiotensina
Rendimiento deportivo
Polymorphism
A-actinin-3
Angiotensin converting enzyme
Sport performance
topic Polimorfismo
A-actinina 3
Enzima convertidora de angiotensina
Rendimiento deportivo
Polymorphism
A-actinin-3
Angiotensin converting enzyme
Sport performance
description In the field of competitive sport, genetics has gained a fundamental role in the study of sport performance. The aim of this study was to analyze the prevalence of polymorphisms R577X and insertion/deletion (I/D), occurring in a-actinin-3 (ACTN3) and angiotensin converting enzyme (ACE) genes, respectively, in Brazilian and Japanese gymnasts. A suitable non-probabilistic sample of 73 gymnasts (14 from Japan) was recruited and signed an informed consent. To measure ACTN3 and ECA saliva samples were obtained by means of real time polymerase chain reaction (iQ5 Thermal Cycler, BioRad). A high prevalence of RX ACTN3 genotype, R allele, ACE I/D genotype, and D allele were observed in Brazilian and Japanese gymnasts. In conclusion a high prevalence of RX ACTN3 genotype, R allele and ACE I/D genotype would allow a genetic advantage regarding muscle strength and power, possibly facilitating competitive success in gymnastics.
publishDate 2015
dc.date.none.fl_str_mv 2015-03
2020-12-08T00:42:23Z
2020-12-08T00:42:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv JOÃO, A. F. et al. Polimorfismo del Gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón. International Journal of Morphology, Temuco, v. 33, n. 1, p. 262-266, marzo 2015. DOI: 10.4067/S0717-95022015000100041.
http://repositorio.ufla.br/jspui/handle/1/45796
identifier_str_mv JOÃO, A. F. et al. Polimorfismo del Gen ACTN3 y ECA en seleccionados de gimnasia de Brasil y Japón. International Journal of Morphology, Temuco, v. 33, n. 1, p. 262-266, marzo 2015. DOI: 10.4067/S0717-95022015000100041.
url http://repositorio.ufla.br/jspui/handle/1/45796
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedad Chilena de Anatomía
publisher.none.fl_str_mv Sociedad Chilena de Anatomía
dc.source.none.fl_str_mv International Journal of Morphology
reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
repository.name.fl_str_mv Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)
repository.mail.fl_str_mv nivaldo@ufla.br || repositorio.biblioteca@ufla.br
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