Syzygium sp (Myrtaceae) extracts: inhibition of alpha amylase

• Autor(a) principal: Freitas, Tuanny Cavatão de
• Data de Publicação: 2014
• Outros Autores: Pereira, Chrystian Araújo, Pereira, Luciana Lopes Silva
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFLA
• Texto Completo: http://repositorio.ufla.br/jspui/handle/1/15209
• topic: Syzygium; Amylase; Gastric fluid; Diabetes - Treatment; Amilase; Fluido gástrico; Diabetes - Tratamento

Aims: The aims of this study were: a) prepare crude extracts of commercial teas Syzygium sp by different methods (maceration, decoction and infusion) in different proportions (1:20, 1:50 and 1:100) and b) submit them the inhibition assays digestive enzyme alpha-amylase before and after exposure to a simulated gastric fluid. Place and Duration of Study: Laboratório de Bioquímica, Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triângulo Mineiro, Brazil, between August 2012 and July 2013. Methodology: Five samples of Syzygium sp teas were purchased commercially from pharmacies, drugstores and health food stores. Results: In the first step - inhibition of enzymatic extracts of the teas without simulated gastric fluid - the results showed significant inhibition of alpha-amylase (mean 92.84%, CV = 3.86%). However, when these extracts were placed in contact with the simulated gastric fluid was observed decreased inhibition of alpha – amylase, suggesting a possible reduction of hypoglycemic potential of these teas under physiological conditions. Conclusion: Aqueous extract Syzygium sp have high percentages of inhibition of the enzyme amylase, suggesting a potential hypoglycemic effect. Additional studies aiming at elucidating the chemical compounds present in the extracts of Syzygium sp using chromatographic techniques will be performed.