Prevalence and factors associated with dyslipidemia after liver transplantation

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Hélem de Sena
Data de Publicação: 2014
Outros Autores: Anastácio, Lucilene Rezende, Ferreira, Lívia Garcia, Lagares, Érika Barbosa, Lima, Agnaldo Soares, Correia, Maria Isabel Toulson Davisson
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFLA
Texto Completo: http://repositorio.ufla.br/jspui/handle/1/38778
Resumo: Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.
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spelling Prevalence and factors associated with dyslipidemia after liver transplantationPrevalência e fatores associados às dislipidemias pós-transplante hepáticoDyslipidemiaLipoproteinLiver transplantationDislipidemiaLipoproteínasTransplante de fígadoObjective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.Objetivo: determinar a prevalência de anormalidades de colesterol total (CT), lipoproteína de baixa densidade (LDL) e alta densidade (HDL) e triglicérides, e identificar fatores preditivos dessas desordens em pacientes submetidos ao transplante hepático (TxH). Métodos: estudo transversal de avaliação da prevalência de dislipidemias em pacientes submetidos ao TxH. Variáveis demográficas, socioeconômicas, clínicas, antropométricas e dietéticas foram coletadas para identificar os fatores associados utilizando análises estatísticas uni e multivariadas. Resultados: foram avaliados 136 pacientes, dos quais 68,1% apresentaram pelo menos um tipo de dislipidemia. O nível de triglicérides esteve elevado em 32,4% dos casos, a HDL reduzida em 49,3% dos pacientes e os níveis de LDL elevados em apenas 8,8%. Colesterol total elevado foi observado em 16,2% da população estudada e esteve associado à indicação de transplante por cirrose etanólica (OR = 2,7) e maior número de horas dormidas por noite (OR = 1,5). Conclusão: grande parte dos pacientes apresentou dislipidemia após o transplante, demonstrando a necessidade de intervenções em relação aos fatores modificáveis associados às dislipidemias que podem atenuar ou prevenir essas desordens.Associação Médica Brasileira2020-01-31T11:39:04Z2020-01-31T11:39:04Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfRIBEIRO, H. de S. et al. Prevalence and factors associated with dyslipidemia after liver transplantation. Revista da Associação Médica Brasileira, São Paulo, v. 60, n. 4, p. 365-372, 2014.http://repositorio.ufla.br/jspui/handle/1/38778Revista da Associação Médica Brasileirareponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessRibeiro, Hélem de SenaAnastácio, Lucilene RezendeFerreira, Lívia GarciaLagares, Érika BarbosaLima, Agnaldo SoaresCorreia, Maria Isabel Toulson Davissoneng2023-04-24T18:18:14Zoai:localhost:1/38778Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2023-04-24T18:18:14Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false
dc.title.none.fl_str_mv Prevalence and factors associated with dyslipidemia after liver transplantation
Prevalência e fatores associados às dislipidemias pós-transplante hepático
title Prevalence and factors associated with dyslipidemia after liver transplantation
spellingShingle Prevalence and factors associated with dyslipidemia after liver transplantation
Ribeiro, Hélem de Sena
Dyslipidemia
Lipoprotein
Liver transplantation
Dislipidemia
Lipoproteínas
Transplante de fígado
title_short Prevalence and factors associated with dyslipidemia after liver transplantation
title_full Prevalence and factors associated with dyslipidemia after liver transplantation
title_fullStr Prevalence and factors associated with dyslipidemia after liver transplantation
title_full_unstemmed Prevalence and factors associated with dyslipidemia after liver transplantation
title_sort Prevalence and factors associated with dyslipidemia after liver transplantation
author Ribeiro, Hélem de Sena
author_facet Ribeiro, Hélem de Sena
Anastácio, Lucilene Rezende
Ferreira, Lívia Garcia
Lagares, Érika Barbosa
Lima, Agnaldo Soares
Correia, Maria Isabel Toulson Davisson
author_role author
author2 Anastácio, Lucilene Rezende
Ferreira, Lívia Garcia
Lagares, Érika Barbosa
Lima, Agnaldo Soares
Correia, Maria Isabel Toulson Davisson
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Hélem de Sena
Anastácio, Lucilene Rezende
Ferreira, Lívia Garcia
Lagares, Érika Barbosa
Lima, Agnaldo Soares
Correia, Maria Isabel Toulson Davisson
dc.subject.por.fl_str_mv Dyslipidemia
Lipoprotein
Liver transplantation
Dislipidemia
Lipoproteínas
Transplante de fígado
topic Dyslipidemia
Lipoprotein
Liver transplantation
Dislipidemia
Lipoproteínas
Transplante de fígado
description Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.
publishDate 2014
dc.date.none.fl_str_mv 2014
2020-01-31T11:39:04Z
2020-01-31T11:39:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv RIBEIRO, H. de S. et al. Prevalence and factors associated with dyslipidemia after liver transplantation. Revista da Associação Médica Brasileira, São Paulo, v. 60, n. 4, p. 365-372, 2014.
http://repositorio.ufla.br/jspui/handle/1/38778
identifier_str_mv RIBEIRO, H. de S. et al. Prevalence and factors associated with dyslipidemia after liver transplantation. Revista da Associação Médica Brasileira, São Paulo, v. 60, n. 4, p. 365-372, 2014.
url http://repositorio.ufla.br/jspui/handle/1/38778
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira
reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
repository.name.fl_str_mv Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)
repository.mail.fl_str_mv nivaldo@ufla.br || repositorio.biblioteca@ufla.br
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