Prevalence and factors associated with dyslipidemia after liver transplantation
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | http://repositorio.ufla.br/jspui/handle/1/38778 |
Resumo: | Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders. |
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Prevalence and factors associated with dyslipidemia after liver transplantationPrevalência e fatores associados às dislipidemias pós-transplante hepáticoDyslipidemiaLipoproteinLiver transplantationDislipidemiaLipoproteínasTransplante de fígadoObjective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.Objetivo: determinar a prevalência de anormalidades de colesterol total (CT), lipoproteína de baixa densidade (LDL) e alta densidade (HDL) e triglicérides, e identificar fatores preditivos dessas desordens em pacientes submetidos ao transplante hepático (TxH). Métodos: estudo transversal de avaliação da prevalência de dislipidemias em pacientes submetidos ao TxH. Variáveis demográficas, socioeconômicas, clínicas, antropométricas e dietéticas foram coletadas para identificar os fatores associados utilizando análises estatísticas uni e multivariadas. Resultados: foram avaliados 136 pacientes, dos quais 68,1% apresentaram pelo menos um tipo de dislipidemia. O nível de triglicérides esteve elevado em 32,4% dos casos, a HDL reduzida em 49,3% dos pacientes e os níveis de LDL elevados em apenas 8,8%. Colesterol total elevado foi observado em 16,2% da população estudada e esteve associado à indicação de transplante por cirrose etanólica (OR = 2,7) e maior número de horas dormidas por noite (OR = 1,5). Conclusão: grande parte dos pacientes apresentou dislipidemia após o transplante, demonstrando a necessidade de intervenções em relação aos fatores modificáveis associados às dislipidemias que podem atenuar ou prevenir essas desordens.Associação Médica Brasileira2020-01-31T11:39:04Z2020-01-31T11:39:04Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfRIBEIRO, H. de S. et al. Prevalence and factors associated with dyslipidemia after liver transplantation. Revista da Associação Médica Brasileira, São Paulo, v. 60, n. 4, p. 365-372, 2014.http://repositorio.ufla.br/jspui/handle/1/38778Revista da Associação Médica Brasileirareponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessRibeiro, Hélem de SenaAnastácio, Lucilene RezendeFerreira, Lívia GarciaLagares, Érika BarbosaLima, Agnaldo SoaresCorreia, Maria Isabel Toulson Davissoneng2023-04-24T18:18:14Zoai:localhost:1/38778Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2023-04-24T18:18:14Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Prevalence and factors associated with dyslipidemia after liver transplantation Prevalência e fatores associados às dislipidemias pós-transplante hepático |
title |
Prevalence and factors associated with dyslipidemia after liver transplantation |
spellingShingle |
Prevalence and factors associated with dyslipidemia after liver transplantation Ribeiro, Hélem de Sena Dyslipidemia Lipoprotein Liver transplantation Dislipidemia Lipoproteínas Transplante de fígado |
title_short |
Prevalence and factors associated with dyslipidemia after liver transplantation |
title_full |
Prevalence and factors associated with dyslipidemia after liver transplantation |
title_fullStr |
Prevalence and factors associated with dyslipidemia after liver transplantation |
title_full_unstemmed |
Prevalence and factors associated with dyslipidemia after liver transplantation |
title_sort |
Prevalence and factors associated with dyslipidemia after liver transplantation |
author |
Ribeiro, Hélem de Sena |
author_facet |
Ribeiro, Hélem de Sena Anastácio, Lucilene Rezende Ferreira, Lívia Garcia Lagares, Érika Barbosa Lima, Agnaldo Soares Correia, Maria Isabel Toulson Davisson |
author_role |
author |
author2 |
Anastácio, Lucilene Rezende Ferreira, Lívia Garcia Lagares, Érika Barbosa Lima, Agnaldo Soares Correia, Maria Isabel Toulson Davisson |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Ribeiro, Hélem de Sena Anastácio, Lucilene Rezende Ferreira, Lívia Garcia Lagares, Érika Barbosa Lima, Agnaldo Soares Correia, Maria Isabel Toulson Davisson |
dc.subject.por.fl_str_mv |
Dyslipidemia Lipoprotein Liver transplantation Dislipidemia Lipoproteínas Transplante de fígado |
topic |
Dyslipidemia Lipoprotein Liver transplantation Dislipidemia Lipoproteínas Transplante de fígado |
description |
Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 2020-01-31T11:39:04Z 2020-01-31T11:39:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
RIBEIRO, H. de S. et al. Prevalence and factors associated with dyslipidemia after liver transplantation. Revista da Associação Médica Brasileira, São Paulo, v. 60, n. 4, p. 365-372, 2014. http://repositorio.ufla.br/jspui/handle/1/38778 |
identifier_str_mv |
RIBEIRO, H. de S. et al. Prevalence and factors associated with dyslipidemia after liver transplantation. Revista da Associação Médica Brasileira, São Paulo, v. 60, n. 4, p. 365-372, 2014. |
url |
http://repositorio.ufla.br/jspui/handle/1/38778 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Associação Médica Brasileira |
publisher.none.fl_str_mv |
Associação Médica Brasileira |
dc.source.none.fl_str_mv |
Revista da Associação Médica Brasileira reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
instname_str |
Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
collection |
Repositório Institucional da UFLA |
repository.name.fl_str_mv |
Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
_version_ |
1815439147810160640 |