Uso do plasma rico em plaquetas na reparação tendínea em ovinos
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | http://repositorio.ufla.br/jspui/handle/1/50797 |
Resumo: | The tendon injuries therapy is recognized as a challenge in human and veterinary medicine, partly due to difficulty of completely restoration the tendon morphology and its biomechanical strength. Platelet-rich plasma (PRP) has been used successfully in the therapy of tendonitis, however, there are still divergent data regarding its effectiveness and the complete mechanism of its action is still unknown. This study aimed to evaluate the effects of PRP in initial wound repair of induced lesion in the superficial digital flexor tendon (SDFT). Partial tenotomy of the palmar SDFT was conducted with the aid of a dermatological punch in 10 male sheep and immediate intra-tendon therapy was instituted with 200μL of autologous PRP in the treated group (TG) and 200μL of 0.9% sodium chloride in the control group (CG). Clinical, thermographic and ultrasound evaluation were performed for 30 days after therapy. There were no changes in clinical assessment between experimental groups. In the thermographic evaluation, an increase in temperature was observed on the surface of the tendon lesion in the CG compared to the TG, 30 days after the therapy. In ultrassonographic evaluation, less edema in the TG compared to CG at moments 01, 02, 10 and 30 days after therapy. These findings suggest modulation of the inflammatory process in response to PRP therapy in the initial phase of tendon repair. |
id |
UFLA_cf455157f0a2bd32c2e7953511ad3a97 |
---|---|
oai_identifier_str |
oai:localhost:1/50797 |
network_acronym_str |
UFLA |
network_name_str |
Repositório Institucional da UFLA |
repository_id_str |
|
spelling |
Uso do plasma rico em plaquetas na reparação tendínea em ovinosUse of platelet-rich plasma in tendon repair in sheepLesões tendíneasTermografiaOvinos - LesõesConcentrado de plaquetastendon injuriesThermographySheep - InjuriesPlatelet concentrateThe tendon injuries therapy is recognized as a challenge in human and veterinary medicine, partly due to difficulty of completely restoration the tendon morphology and its biomechanical strength. Platelet-rich plasma (PRP) has been used successfully in the therapy of tendonitis, however, there are still divergent data regarding its effectiveness and the complete mechanism of its action is still unknown. This study aimed to evaluate the effects of PRP in initial wound repair of induced lesion in the superficial digital flexor tendon (SDFT). Partial tenotomy of the palmar SDFT was conducted with the aid of a dermatological punch in 10 male sheep and immediate intra-tendon therapy was instituted with 200μL of autologous PRP in the treated group (TG) and 200μL of 0.9% sodium chloride in the control group (CG). Clinical, thermographic and ultrasound evaluation were performed for 30 days after therapy. There were no changes in clinical assessment between experimental groups. In the thermographic evaluation, an increase in temperature was observed on the surface of the tendon lesion in the CG compared to the TG, 30 days after the therapy. In ultrassonographic evaluation, less edema in the TG compared to CG at moments 01, 02, 10 and 30 days after therapy. These findings suggest modulation of the inflammatory process in response to PRP therapy in the initial phase of tendon repair.A terapia de lesões tendíneas é reconhecida como um desafio na medicina humana e veterinária, em parte devido à dificuldade do completo restabelecimento da morfologia do tendão e de sua resistência biomecânica. O plasma rico em plaquetas (PRP) tem sido utilizado com sucesso na terapia da tendinite, no entanto, ainda há dados divergentes quanto a sua eficácia e não se tem o completo conhecimento de seu mecanismo de ação. Este estudo teve como objetivo avaliar os efeitos do PRP na fase inicial da reparação da lesão induzida no tendão flexor digital superficial (TFDS). Foi realizada tenotomia parcial da face palmar do TFDS com o auxílio de punch dermatológico em 10 ovinos machos e imediatamente instituída a terapia intra-tendínea com 200 µL de PRP autólogo no grupo tratado (GT) e 200 µL de cloreto de sódio 0,9% no grupo controle (GC). Foram realizadas avaliações clínicas, termográficas e ultrassonográficas durante 30 dias após a terapia. Não foram observadas alterações na avaliação clínica entre os diferentes grupos experimentais. Na avaliação termográfica foi observado aumento de temperatura sobre a superfície da lesão tendínea no GC comparado ao GT, após 30 dias da terapia. Na avaliação ultrassonográfica foi evidenciado menor edema no GT comparado ao GC nos momentos 01, 02, 10 e 30 dias após a terapia. Estes achados sugerem modulação do processo inflamatório em resposta a terapia com PRP na fase inicial da reparação tendínea.Universidade Federal Rural de Pernambuco2022-08-02T21:07:17Z2022-08-02T21:07:17Z2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfPINHEIRO, J. C. M. N. et al. Uso do plasma rico em plaquetas na reparação tendínea em ovinos. Medicina Veterinária, Recife, v. 15, n. 4, p. 324-331, 2021. DOI: 10.26605/medvet-v15n4-3591.http://repositorio.ufla.br/jspui/handle/1/50797Medicina Veterináriareponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessPinheiro, Jeandra Carla Mattos NascimentoSouza, Cauê NatamToma, Hugo ShiseiMuraro, Lívia SaabXavier, Andressa Batista SilveiraSantos, Marcelo DinizCarvalho, Armando Mattospor2022-08-02T21:07:17Zoai:localhost:1/50797Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2022-08-02T21:07:17Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos Use of platelet-rich plasma in tendon repair in sheep |
title |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos |
spellingShingle |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos Pinheiro, Jeandra Carla Mattos Nascimento Lesões tendíneas Termografia Ovinos - Lesões Concentrado de plaquetas tendon injuries Thermography Sheep - Injuries Platelet concentrate |
title_short |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos |
title_full |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos |
title_fullStr |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos |
title_full_unstemmed |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos |
title_sort |
Uso do plasma rico em plaquetas na reparação tendínea em ovinos |
author |
Pinheiro, Jeandra Carla Mattos Nascimento |
author_facet |
Pinheiro, Jeandra Carla Mattos Nascimento Souza, Cauê Natam Toma, Hugo Shisei Muraro, Lívia Saab Xavier, Andressa Batista Silveira Santos, Marcelo Diniz Carvalho, Armando Mattos |
author_role |
author |
author2 |
Souza, Cauê Natam Toma, Hugo Shisei Muraro, Lívia Saab Xavier, Andressa Batista Silveira Santos, Marcelo Diniz Carvalho, Armando Mattos |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Pinheiro, Jeandra Carla Mattos Nascimento Souza, Cauê Natam Toma, Hugo Shisei Muraro, Lívia Saab Xavier, Andressa Batista Silveira Santos, Marcelo Diniz Carvalho, Armando Mattos |
dc.subject.por.fl_str_mv |
Lesões tendíneas Termografia Ovinos - Lesões Concentrado de plaquetas tendon injuries Thermography Sheep - Injuries Platelet concentrate |
topic |
Lesões tendíneas Termografia Ovinos - Lesões Concentrado de plaquetas tendon injuries Thermography Sheep - Injuries Platelet concentrate |
description |
The tendon injuries therapy is recognized as a challenge in human and veterinary medicine, partly due to difficulty of completely restoration the tendon morphology and its biomechanical strength. Platelet-rich plasma (PRP) has been used successfully in the therapy of tendonitis, however, there are still divergent data regarding its effectiveness and the complete mechanism of its action is still unknown. This study aimed to evaluate the effects of PRP in initial wound repair of induced lesion in the superficial digital flexor tendon (SDFT). Partial tenotomy of the palmar SDFT was conducted with the aid of a dermatological punch in 10 male sheep and immediate intra-tendon therapy was instituted with 200μL of autologous PRP in the treated group (TG) and 200μL of 0.9% sodium chloride in the control group (CG). Clinical, thermographic and ultrasound evaluation were performed for 30 days after therapy. There were no changes in clinical assessment between experimental groups. In the thermographic evaluation, an increase in temperature was observed on the surface of the tendon lesion in the CG compared to the TG, 30 days after the therapy. In ultrassonographic evaluation, less edema in the TG compared to CG at moments 01, 02, 10 and 30 days after therapy. These findings suggest modulation of the inflammatory process in response to PRP therapy in the initial phase of tendon repair. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021 2022-08-02T21:07:17Z 2022-08-02T21:07:17Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
PINHEIRO, J. C. M. N. et al. Uso do plasma rico em plaquetas na reparação tendínea em ovinos. Medicina Veterinária, Recife, v. 15, n. 4, p. 324-331, 2021. DOI: 10.26605/medvet-v15n4-3591. http://repositorio.ufla.br/jspui/handle/1/50797 |
identifier_str_mv |
PINHEIRO, J. C. M. N. et al. Uso do plasma rico em plaquetas na reparação tendínea em ovinos. Medicina Veterinária, Recife, v. 15, n. 4, p. 324-331, 2021. DOI: 10.26605/medvet-v15n4-3591. |
url |
http://repositorio.ufla.br/jspui/handle/1/50797 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal Rural de Pernambuco |
publisher.none.fl_str_mv |
Universidade Federal Rural de Pernambuco |
dc.source.none.fl_str_mv |
Medicina Veterinária reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
instname_str |
Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
collection |
Repositório Institucional da UFLA |
repository.name.fl_str_mv |
Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
_version_ |
1815439081870458880 |