Uso do plasma rico em plaquetas na reparação tendínea em ovinos

Detalhes bibliográficos
Autor(a) principal: Pinheiro, Jeandra Carla Mattos Nascimento
Data de Publicação: 2021
Outros Autores: Souza, Cauê Natam, Toma, Hugo Shisei, Muraro, Lívia Saab, Xavier, Andressa Batista Silveira, Santos, Marcelo Diniz, Carvalho, Armando Mattos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFLA
Texto Completo: http://repositorio.ufla.br/jspui/handle/1/50797
Resumo: The tendon injuries therapy is recognized as a challenge in human and veterinary medicine, partly due to difficulty of completely restoration the tendon morphology and its biomechanical strength. Platelet-rich plasma (PRP) has been used successfully in the therapy of tendonitis, however, there are still divergent data regarding its effectiveness and the complete mechanism of its action is still unknown. This study aimed to evaluate the effects of PRP in initial wound repair of induced lesion in the superficial digital flexor tendon (SDFT). Partial tenotomy of the palmar SDFT was conducted with the aid of a dermatological punch in 10 male sheep and immediate intra-tendon therapy was instituted with 200μL of autologous PRP in the treated group (TG) and 200μL of 0.9% sodium chloride in the control group (CG). Clinical, thermographic and ultrasound evaluation were performed for 30 days after therapy. There were no changes in clinical assessment between experimental groups. In the thermographic evaluation, an increase in temperature was observed on the surface of the tendon lesion in the CG compared to the TG, 30 days after the therapy. In ultrassonographic evaluation, less edema in the TG compared to CG at moments 01, 02, 10 and 30 days after therapy. These findings suggest modulation of the inflammatory process in response to PRP therapy in the initial phase of tendon repair.
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spelling Uso do plasma rico em plaquetas na reparação tendínea em ovinosUse of platelet-rich plasma in tendon repair in sheepLesões tendíneasTermografiaOvinos - LesõesConcentrado de plaquetastendon injuriesThermographySheep - InjuriesPlatelet concentrateThe tendon injuries therapy is recognized as a challenge in human and veterinary medicine, partly due to difficulty of completely restoration the tendon morphology and its biomechanical strength. Platelet-rich plasma (PRP) has been used successfully in the therapy of tendonitis, however, there are still divergent data regarding its effectiveness and the complete mechanism of its action is still unknown. This study aimed to evaluate the effects of PRP in initial wound repair of induced lesion in the superficial digital flexor tendon (SDFT). Partial tenotomy of the palmar SDFT was conducted with the aid of a dermatological punch in 10 male sheep and immediate intra-tendon therapy was instituted with 200μL of autologous PRP in the treated group (TG) and 200μL of 0.9% sodium chloride in the control group (CG). Clinical, thermographic and ultrasound evaluation were performed for 30 days after therapy. There were no changes in clinical assessment between experimental groups. In the thermographic evaluation, an increase in temperature was observed on the surface of the tendon lesion in the CG compared to the TG, 30 days after the therapy. In ultrassonographic evaluation, less edema in the TG compared to CG at moments 01, 02, 10 and 30 days after therapy. These findings suggest modulation of the inflammatory process in response to PRP therapy in the initial phase of tendon repair.A terapia de lesões tendíneas é reconhecida como um desafio na medicina humana e veterinária, em parte devido à dificuldade do completo restabelecimento da morfologia do tendão e de sua resistência biomecânica. O plasma rico em plaquetas (PRP) tem sido utilizado com sucesso na terapia da tendinite, no entanto, ainda há dados divergentes quanto a sua eficácia e não se tem o completo conhecimento de seu mecanismo de ação. Este estudo teve como objetivo avaliar os efeitos do PRP na fase inicial da reparação da lesão induzida no tendão flexor digital superficial (TFDS). Foi realizada tenotomia parcial da face palmar do TFDS com o auxílio de punch dermatológico em 10 ovinos machos e imediatamente instituída a terapia intra-tendínea com 200 µL de PRP autólogo no grupo tratado (GT) e 200 µL de cloreto de sódio 0,9% no grupo controle (GC). Foram realizadas avaliações clínicas, termográficas e ultrassonográficas durante 30 dias após a terapia. Não foram observadas alterações na avaliação clínica entre os diferentes grupos experimentais. Na avaliação termográfica foi observado aumento de temperatura sobre a superfície da lesão tendínea no GC comparado ao GT, após 30 dias da terapia. Na avaliação ultrassonográfica foi evidenciado menor edema no GT comparado ao GC nos momentos 01, 02, 10 e 30 dias após a terapia. Estes achados sugerem modulação do processo inflamatório em resposta a terapia com PRP na fase inicial da reparação tendínea.Universidade Federal Rural de Pernambuco2022-08-02T21:07:17Z2022-08-02T21:07:17Z2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfPINHEIRO, J. C. M. N. et al. Uso do plasma rico em plaquetas na reparação tendínea em ovinos. Medicina Veterinária, Recife, v. 15, n. 4, p. 324-331, 2021. DOI: 10.26605/medvet-v15n4-3591.http://repositorio.ufla.br/jspui/handle/1/50797Medicina Veterináriareponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessPinheiro, Jeandra Carla Mattos NascimentoSouza, Cauê NatamToma, Hugo ShiseiMuraro, Lívia SaabXavier, Andressa Batista SilveiraSantos, Marcelo DinizCarvalho, Armando Mattospor2022-08-02T21:07:17Zoai:localhost:1/50797Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2022-08-02T21:07:17Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false
dc.title.none.fl_str_mv Uso do plasma rico em plaquetas na reparação tendínea em ovinos
Use of platelet-rich plasma in tendon repair in sheep
title Uso do plasma rico em plaquetas na reparação tendínea em ovinos
spellingShingle Uso do plasma rico em plaquetas na reparação tendínea em ovinos
Pinheiro, Jeandra Carla Mattos Nascimento
Lesões tendíneas
Termografia
Ovinos - Lesões
Concentrado de plaquetas
tendon injuries
Thermography
Sheep - Injuries
Platelet concentrate
title_short Uso do plasma rico em plaquetas na reparação tendínea em ovinos
title_full Uso do plasma rico em plaquetas na reparação tendínea em ovinos
title_fullStr Uso do plasma rico em plaquetas na reparação tendínea em ovinos
title_full_unstemmed Uso do plasma rico em plaquetas na reparação tendínea em ovinos
title_sort Uso do plasma rico em plaquetas na reparação tendínea em ovinos
author Pinheiro, Jeandra Carla Mattos Nascimento
author_facet Pinheiro, Jeandra Carla Mattos Nascimento
Souza, Cauê Natam
Toma, Hugo Shisei
Muraro, Lívia Saab
Xavier, Andressa Batista Silveira
Santos, Marcelo Diniz
Carvalho, Armando Mattos
author_role author
author2 Souza, Cauê Natam
Toma, Hugo Shisei
Muraro, Lívia Saab
Xavier, Andressa Batista Silveira
Santos, Marcelo Diniz
Carvalho, Armando Mattos
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pinheiro, Jeandra Carla Mattos Nascimento
Souza, Cauê Natam
Toma, Hugo Shisei
Muraro, Lívia Saab
Xavier, Andressa Batista Silveira
Santos, Marcelo Diniz
Carvalho, Armando Mattos
dc.subject.por.fl_str_mv Lesões tendíneas
Termografia
Ovinos - Lesões
Concentrado de plaquetas
tendon injuries
Thermography
Sheep - Injuries
Platelet concentrate
topic Lesões tendíneas
Termografia
Ovinos - Lesões
Concentrado de plaquetas
tendon injuries
Thermography
Sheep - Injuries
Platelet concentrate
description The tendon injuries therapy is recognized as a challenge in human and veterinary medicine, partly due to difficulty of completely restoration the tendon morphology and its biomechanical strength. Platelet-rich plasma (PRP) has been used successfully in the therapy of tendonitis, however, there are still divergent data regarding its effectiveness and the complete mechanism of its action is still unknown. This study aimed to evaluate the effects of PRP in initial wound repair of induced lesion in the superficial digital flexor tendon (SDFT). Partial tenotomy of the palmar SDFT was conducted with the aid of a dermatological punch in 10 male sheep and immediate intra-tendon therapy was instituted with 200μL of autologous PRP in the treated group (TG) and 200μL of 0.9% sodium chloride in the control group (CG). Clinical, thermographic and ultrasound evaluation were performed for 30 days after therapy. There were no changes in clinical assessment between experimental groups. In the thermographic evaluation, an increase in temperature was observed on the surface of the tendon lesion in the CG compared to the TG, 30 days after the therapy. In ultrassonographic evaluation, less edema in the TG compared to CG at moments 01, 02, 10 and 30 days after therapy. These findings suggest modulation of the inflammatory process in response to PRP therapy in the initial phase of tendon repair.
publishDate 2021
dc.date.none.fl_str_mv 2021
2022-08-02T21:07:17Z
2022-08-02T21:07:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv PINHEIRO, J. C. M. N. et al. Uso do plasma rico em plaquetas na reparação tendínea em ovinos. Medicina Veterinária, Recife, v. 15, n. 4, p. 324-331, 2021. DOI: 10.26605/medvet-v15n4-3591.
http://repositorio.ufla.br/jspui/handle/1/50797
identifier_str_mv PINHEIRO, J. C. M. N. et al. Uso do plasma rico em plaquetas na reparação tendínea em ovinos. Medicina Veterinária, Recife, v. 15, n. 4, p. 324-331, 2021. DOI: 10.26605/medvet-v15n4-3591.
url http://repositorio.ufla.br/jspui/handle/1/50797
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Attribution-NonCommercial-ShareAlike 4.0 International
http://creativecommons.org/licenses/by-nc-sa/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-ShareAlike 4.0 International
http://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal Rural de Pernambuco
publisher.none.fl_str_mv Universidade Federal Rural de Pernambuco
dc.source.none.fl_str_mv Medicina Veterinária
reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
repository.name.fl_str_mv Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)
repository.mail.fl_str_mv nivaldo@ufla.br || repositorio.biblioteca@ufla.br
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