QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?

Detalhes bibliográficos
Autor(a) principal: Oliveira, Maira S.
Data de Publicação: 2014
Outros Autores: Muzzi, Ruthnéa A. L., Muzzi, Leonardo A. L., Cherem, Marcos, Mantovani, Matheus M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFLA
Texto Completo: http://repositorio.ufla.br/jspui/handle/1/38889
Resumo: The electrocardiography (ECG) QT interval is influenced by fluctuations in heart rate (HR) what may lead to misinterpretation of its length. Considering that alterations in QT interval length reflect abnormalities of the ventricular repolarisation which predispose to occurrence of arrhythmias, this variable must be properly evaluated. The aim of this work is to determine which method of correcting the QT interval is the most appropriate for dogs regarding different ranges of normal HR (different breeds). Healthy adult dogs (n=130; German Shepherd, Boxer, Pit Bull Terrier, and Poodle) were submitted to ECG examination and QT intervals were determined in triplicates from the bipolar limb II lead and corrected for the effects of HR through the application of three published formulae involving quadratic, cubic or linear regression. The mean corrected QT values (QTc) obtained using the diverse formulae were significantly different (ρ<0.05), while those derived according to the equation QTcV = QT + 0.087(1- RR) were the most consistent (linear regression). QTcV values were strongly correlated (r=0.83) with the QT interval and showed a coefficient of variation of 8.37% and a 95% confidence interval of 0.22-0.23 s. Owing to its simplicity and reliability, the QTcV was considered the most appropriate to be used for the correction of QT interval in dogs.
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spelling QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?Intervalo QT em cães hígidos: qual método de correção para o intervalo QT é mais apropriado na clínica de pequenos animais?Dogs - ElectrocardiographyDogs - Heart rateCães - EletrocardiogramaCães - Frequência cardíacaThe electrocardiography (ECG) QT interval is influenced by fluctuations in heart rate (HR) what may lead to misinterpretation of its length. Considering that alterations in QT interval length reflect abnormalities of the ventricular repolarisation which predispose to occurrence of arrhythmias, this variable must be properly evaluated. The aim of this work is to determine which method of correcting the QT interval is the most appropriate for dogs regarding different ranges of normal HR (different breeds). Healthy adult dogs (n=130; German Shepherd, Boxer, Pit Bull Terrier, and Poodle) were submitted to ECG examination and QT intervals were determined in triplicates from the bipolar limb II lead and corrected for the effects of HR through the application of three published formulae involving quadratic, cubic or linear regression. The mean corrected QT values (QTc) obtained using the diverse formulae were significantly different (ρ<0.05), while those derived according to the equation QTcV = QT + 0.087(1- RR) were the most consistent (linear regression). QTcV values were strongly correlated (r=0.83) with the QT interval and showed a coefficient of variation of 8.37% and a 95% confidence interval of 0.22-0.23 s. Owing to its simplicity and reliability, the QTcV was considered the most appropriate to be used for the correction of QT interval in dogs.O intervalo QT do eletrocardiograma (ECG) é influenciado por variações da frequência cardíaca (FC), o que pode levar a erros na interpretação de sua duração. Considerando que as alterações na duração do intervalo QT refletem anormalidades da repolarização ventricular, as quais predispõem a ocorrência de arritmias, esta variável deve ser devidamente avaliada. O objetivo deste trabalho foi determinar qual método de correção do intervalo QT é mais adequado para os cães, considerando-se diferentes intervalos de FC normais. Cães adultos saudáveis, de diferentes raças (n=130; Pastor Alemão, Boxer, Pit Bull Terrier e Poodle) foram submetidos ao exame eletrocardiográfico, no qual se determinaram os intervalos QT a partir da derivação bipolar II e foram corrigidos os efeitos da FC por meio da aplicação de três fórmulas, envolvendo regressão quadrática, cúbica ou linear. Os valores do QT corrigido (QTc) obtidos utilizando as diversas fórmulas foram significativamente diferentes (ρ<0,05), sendo os derivados da equação QTcV = QT + 0,087 (1- RR), os mais consistentes (regressão linear). Valores de QTcV apresentaram correlação significativa e de alta magnitude (r=0,83) com o intervalo QT, baixo coeficiente de variação (8,37%) e intervalo de confiança de 95% de 0,22-0,23s. Devido à confiabilidade dos dados, o QTcV foi considerado o mais apropriado para ser utilizado para a correção do intervalo QT em cães, além de ser um método de fácil execução.Colégio Brasileiro de Patologia Animal2020-02-06T11:47:52Z2020-02-06T11:47:52Z2014-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfOLIVEIRA, M. S.; MUZZI, R. A. L.; MUZZI, L. A. L.; CHEREM, M.; MANTOVANI, M. M. QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics? Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 34, n. 5, p. 469-472, maio 2014.http://repositorio.ufla.br/jspui/handle/1/38889Pesquisa Veterinária Brasileirareponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessOliveira, Maira S.Muzzi, Ruthnéa A. L.Muzzi, Leonardo A. L.Cherem, MarcosMantovani, Matheus M.eng2020-02-06T11:47:52Zoai:localhost:1/38889Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2020-02-06T11:47:52Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false
dc.title.none.fl_str_mv QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
Intervalo QT em cães hígidos: qual método de correção para o intervalo QT é mais apropriado na clínica de pequenos animais?
title QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
spellingShingle QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
Oliveira, Maira S.
Dogs - Electrocardiography
Dogs - Heart rate
Cães - Eletrocardiograma
Cães - Frequência cardíaca
title_short QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
title_full QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
title_fullStr QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
title_full_unstemmed QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
title_sort QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics?
author Oliveira, Maira S.
author_facet Oliveira, Maira S.
Muzzi, Ruthnéa A. L.
Muzzi, Leonardo A. L.
Cherem, Marcos
Mantovani, Matheus M.
author_role author
author2 Muzzi, Ruthnéa A. L.
Muzzi, Leonardo A. L.
Cherem, Marcos
Mantovani, Matheus M.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Maira S.
Muzzi, Ruthnéa A. L.
Muzzi, Leonardo A. L.
Cherem, Marcos
Mantovani, Matheus M.
dc.subject.por.fl_str_mv Dogs - Electrocardiography
Dogs - Heart rate
Cães - Eletrocardiograma
Cães - Frequência cardíaca
topic Dogs - Electrocardiography
Dogs - Heart rate
Cães - Eletrocardiograma
Cães - Frequência cardíaca
description The electrocardiography (ECG) QT interval is influenced by fluctuations in heart rate (HR) what may lead to misinterpretation of its length. Considering that alterations in QT interval length reflect abnormalities of the ventricular repolarisation which predispose to occurrence of arrhythmias, this variable must be properly evaluated. The aim of this work is to determine which method of correcting the QT interval is the most appropriate for dogs regarding different ranges of normal HR (different breeds). Healthy adult dogs (n=130; German Shepherd, Boxer, Pit Bull Terrier, and Poodle) were submitted to ECG examination and QT intervals were determined in triplicates from the bipolar limb II lead and corrected for the effects of HR through the application of three published formulae involving quadratic, cubic or linear regression. The mean corrected QT values (QTc) obtained using the diverse formulae were significantly different (ρ<0.05), while those derived according to the equation QTcV = QT + 0.087(1- RR) were the most consistent (linear regression). QTcV values were strongly correlated (r=0.83) with the QT interval and showed a coefficient of variation of 8.37% and a 95% confidence interval of 0.22-0.23 s. Owing to its simplicity and reliability, the QTcV was considered the most appropriate to be used for the correction of QT interval in dogs.
publishDate 2014
dc.date.none.fl_str_mv 2014-05
2020-02-06T11:47:52Z
2020-02-06T11:47:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv OLIVEIRA, M. S.; MUZZI, R. A. L.; MUZZI, L. A. L.; CHEREM, M.; MANTOVANI, M. M. QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics? Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 34, n. 5, p. 469-472, maio 2014.
http://repositorio.ufla.br/jspui/handle/1/38889
identifier_str_mv OLIVEIRA, M. S.; MUZZI, R. A. L.; MUZZI, L. A. L.; CHEREM, M.; MANTOVANI, M. M. QT interval in healthy dogs: which method of correcting the QT interval in dogs is appropriate for use in small animal clinics? Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 34, n. 5, p. 469-472, maio 2014.
url http://repositorio.ufla.br/jspui/handle/1/38889
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal
publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal
dc.source.none.fl_str_mv Pesquisa Veterinária Brasileira
reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
repository.name.fl_str_mv Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)
repository.mail.fl_str_mv nivaldo@ufla.br || repositorio.biblioteca@ufla.br
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