Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19

Detalhes bibliográficos
Autor(a) principal: CUNHA, Cláudia Regina Silva dos Santos
Data de Publicação: 2023
Tipo de documento: Tese
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFMA
Texto Completo: https://tedebc.ufma.br/jspui/handle/tede/tede/4942
Resumo: The present work delimited about the immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the COVID-19 pandemic. The methodology was guided by a systematic literature review and cross-sectional observational studies that resulted in the chapters presented in this thesis. With this study, it was possible to observe that the immunological interferences of COVID-19 infection in the body of the newborn are inconclusive. However, positive correlations were found between maternal COVID-19 infection and the levels of erythrocytes, hematocrit, hemoglobin, basophils, calcium and potassium of the newborn. It was possible to infer that the main interruptions of pregnancies before and during the COVID-19 pandemic occurred mainly due to cardiovascular complications evidenced by predisposing factors such as plateletosis, anemia and vascular resistance. And that prematurity is the main factor for hospitalization of neonates in intensive care units regardless of whether public or private service is provided. Thus, with this study, it is concluded that follow up studies are important for further evaluation of the repercussion of COVID-19 infection on the infant immune system, including the possibility of including evaluations of complete blood counts and biochemistry of these children at the time of collection of the foot test.
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spelling GUERRA, Rosane Nassar Meireleshttp://lattes.cnpq.br/2316192786452127GUERRA, Rosane Nassar Meireleshttp://lattes.cnpq.br/2316192786452127BRANCO, Maria dos Remédios Freitas Carvalhohttp://lattes.cnpq.br/5449951869928014NASCIMENTO, Johnny Ramos dohttp://lattes.cnpq.br/8835152858874648ARAGÃO, Mônica Virginia Viégas Lima dehttp://lattes.cnpq.br/2052899976995482SILVA, Mayara Cristina Pintohttp://lattes.cnpq.br/9507590466760552http://lattes.cnpq.br/0650397814124633CUNHA, Cláudia Regina Silva dos Santos2023-09-13T17:19:36Z2023-08-24CUNHA, Cláudia Regina Silva dos Santos. Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19. 2023. 101 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís, 2023.https://tedebc.ufma.br/jspui/handle/tede/tede/4942The present work delimited about the immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the COVID-19 pandemic. The methodology was guided by a systematic literature review and cross-sectional observational studies that resulted in the chapters presented in this thesis. With this study, it was possible to observe that the immunological interferences of COVID-19 infection in the body of the newborn are inconclusive. However, positive correlations were found between maternal COVID-19 infection and the levels of erythrocytes, hematocrit, hemoglobin, basophils, calcium and potassium of the newborn. It was possible to infer that the main interruptions of pregnancies before and during the COVID-19 pandemic occurred mainly due to cardiovascular complications evidenced by predisposing factors such as plateletosis, anemia and vascular resistance. And that prematurity is the main factor for hospitalization of neonates in intensive care units regardless of whether public or private service is provided. Thus, with this study, it is concluded that follow up studies are important for further evaluation of the repercussion of COVID-19 infection on the infant immune system, including the possibility of including evaluations of complete blood counts and biochemistry of these children at the time of collection of the foot test.O presente trabalho delimitou acerca do perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da COVID-19. A metodologia foi orientada por uma revisão de literatura sistemática e estudos observacionais do tipo transversal que resultaram nos capítulos apresentados nessa tese. Com esse estudo foi possível observar que são inconclusivas as interferências imunológicas da infecção pela COVID-19 no organismo dos nenonatos. No entanto, constatou-se correlações positivas entre a infecção materna por COVID-19 e o hematócrito, os números de eritrócitos e basófilos, os percentuais de hemoglobina e as concnetrações de cálcio e potássio do recém- nascido. Os resultados motraram que as principais causa de interrupções das gestações antes e durante a pandemia da COVID-19 ocorreram por complicações cardiovasculares decorrentes de fatores predisponentes como plaquetose, anemia e resistência vascular. Os dados mostraram também que a prematuridade foi a principal causa de internação dos neonatos em unidades de terapias intensivas, tanto no serviço público como no privado. Assim, foi possivel concluir que os estudos de follow up, de longa duração, são importantes para posterior avaliação da repercussão da COVID-19 sobre o sistema imune infantil e também que é importante incluir os exames bioquimicos e o hemogramas na rotina nos recém-nascidos, o que pode inclusive ocorrer durante a coleta para realização do teste do pezinho.Submitted by Jonathan Sousa de Almeida (jonathan.sousa@ufma.br) on 2023-09-13T17:19:36Z No. of bitstreams: 1 CLÁUDIAREGINASILVADOSSANTOSCUNHA.pdf: 1768055 bytes, checksum: 593d34ad8e3315fe1c05eab93f1e4244 (MD5)Made available in DSpace on 2023-09-13T17:19:36Z (GMT). No. of bitstreams: 1 CLÁUDIAREGINASILVADOSSANTOSCUNHA.pdf: 1768055 bytes, checksum: 593d34ad8e3315fe1c05eab93f1e4244 (MD5) Previous issue date: 2023-08-24FAPEMACAPESapplication/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBSUFMABrasilDEPARTAMENTO DE BIOLOGIA/CCBSCOVID-19;anticorpos;neonatos;leite materno;hemograma.COVID-19;antibodies;newborn;breast Milk;blood count.Saúde Materno-InfantilCiências da SaúdePerfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19Immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the covid-19 pandemicinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMAORIGINALCLÁUDIAREGINASILVADOSSANTOSCUNHA.pdfCLÁUDIAREGINASILVADOSSANTOSCUNHA.pdfapplication/pdf1768055http://tedebc.ufma.br:8080/bitstream/tede/4942/2/CL%C3%81UDIAREGINASILVADOSSANTOSCUNHA.pdf593d34ad8e3315fe1c05eab93f1e4244MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82255http://tedebc.ufma.br:8080/bitstream/tede/4942/1/license.txt97eeade1fce43278e63fe063657f8083MD51tede/49422023-09-13 14:19:36.603oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttps://tedebc.ufma.br/jspui/PUBhttp://tedebc.ufma.br:8080/oai/requestrepositorio@ufma.br||repositorio@ufma.bropendoar:21312023-09-13T17:19:36Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA)false
dc.title.por.fl_str_mv Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
dc.title.alternative.eng.fl_str_mv Immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the covid-19 pandemic
title Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
spellingShingle Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
CUNHA, Cláudia Regina Silva dos Santos
COVID-19;
anticorpos;
neonatos;
leite materno;
hemograma.
COVID-19;
antibodies;
newborn;
breast Milk;
blood count.
Saúde Materno-Infantil
Ciências da Saúde
title_short Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
title_full Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
title_fullStr Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
title_full_unstemmed Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
title_sort Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
author CUNHA, Cláudia Regina Silva dos Santos
author_facet CUNHA, Cláudia Regina Silva dos Santos
author_role author
dc.contributor.advisor1.fl_str_mv GUERRA, Rosane Nassar Meireles
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/2316192786452127
dc.contributor.referee1.fl_str_mv GUERRA, Rosane Nassar Meireles
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/2316192786452127
dc.contributor.referee2.fl_str_mv BRANCO, Maria dos Remédios Freitas Carvalho
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/5449951869928014
dc.contributor.referee3.fl_str_mv NASCIMENTO, Johnny Ramos do
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/8835152858874648
dc.contributor.referee4.fl_str_mv ARAGÃO, Mônica Virginia Viégas Lima de
dc.contributor.referee4Lattes.fl_str_mv http://lattes.cnpq.br/2052899976995482
dc.contributor.referee5.fl_str_mv SILVA, Mayara Cristina Pinto
dc.contributor.referee5Lattes.fl_str_mv http://lattes.cnpq.br/9507590466760552
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0650397814124633
dc.contributor.author.fl_str_mv CUNHA, Cláudia Regina Silva dos Santos
contributor_str_mv GUERRA, Rosane Nassar Meireles
GUERRA, Rosane Nassar Meireles
BRANCO, Maria dos Remédios Freitas Carvalho
NASCIMENTO, Johnny Ramos do
ARAGÃO, Mônica Virginia Viégas Lima de
SILVA, Mayara Cristina Pinto
dc.subject.por.fl_str_mv COVID-19;
anticorpos;
neonatos;
leite materno;
hemograma.
topic COVID-19;
anticorpos;
neonatos;
leite materno;
hemograma.
COVID-19;
antibodies;
newborn;
breast Milk;
blood count.
Saúde Materno-Infantil
Ciências da Saúde
dc.subject.eng.fl_str_mv COVID-19;
antibodies;
newborn;
breast Milk;
blood count.
dc.subject.cnpq.fl_str_mv Saúde Materno-Infantil
Ciências da Saúde
description The present work delimited about the immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the COVID-19 pandemic. The methodology was guided by a systematic literature review and cross-sectional observational studies that resulted in the chapters presented in this thesis. With this study, it was possible to observe that the immunological interferences of COVID-19 infection in the body of the newborn are inconclusive. However, positive correlations were found between maternal COVID-19 infection and the levels of erythrocytes, hematocrit, hemoglobin, basophils, calcium and potassium of the newborn. It was possible to infer that the main interruptions of pregnancies before and during the COVID-19 pandemic occurred mainly due to cardiovascular complications evidenced by predisposing factors such as plateletosis, anemia and vascular resistance. And that prematurity is the main factor for hospitalization of neonates in intensive care units regardless of whether public or private service is provided. Thus, with this study, it is concluded that follow up studies are important for further evaluation of the repercussion of COVID-19 infection on the infant immune system, including the possibility of including evaluations of complete blood counts and biochemistry of these children at the time of collection of the foot test.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-09-13T17:19:36Z
dc.date.issued.fl_str_mv 2023-08-24
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dc.identifier.citation.fl_str_mv CUNHA, Cláudia Regina Silva dos Santos. Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19. 2023. 101 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís, 2023.
dc.identifier.uri.fl_str_mv https://tedebc.ufma.br/jspui/handle/tede/tede/4942
identifier_str_mv CUNHA, Cláudia Regina Silva dos Santos. Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19. 2023. 101 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís, 2023.
url https://tedebc.ufma.br/jspui/handle/tede/tede/4942
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dc.publisher.none.fl_str_mv Universidade Federal do Maranhão
dc.publisher.program.fl_str_mv PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBS
dc.publisher.initials.fl_str_mv UFMA
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv DEPARTAMENTO DE BIOLOGIA/CCBS
publisher.none.fl_str_mv Universidade Federal do Maranhão
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