Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFMA |
Texto Completo: | https://tedebc.ufma.br/jspui/handle/tede/tede/4942 |
Resumo: | The present work delimited about the immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the COVID-19 pandemic. The methodology was guided by a systematic literature review and cross-sectional observational studies that resulted in the chapters presented in this thesis. With this study, it was possible to observe that the immunological interferences of COVID-19 infection in the body of the newborn are inconclusive. However, positive correlations were found between maternal COVID-19 infection and the levels of erythrocytes, hematocrit, hemoglobin, basophils, calcium and potassium of the newborn. It was possible to infer that the main interruptions of pregnancies before and during the COVID-19 pandemic occurred mainly due to cardiovascular complications evidenced by predisposing factors such as plateletosis, anemia and vascular resistance. And that prematurity is the main factor for hospitalization of neonates in intensive care units regardless of whether public or private service is provided. Thus, with this study, it is concluded that follow up studies are important for further evaluation of the repercussion of COVID-19 infection on the infant immune system, including the possibility of including evaluations of complete blood counts and biochemistry of these children at the time of collection of the foot test. |
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GUERRA, Rosane Nassar Meireleshttp://lattes.cnpq.br/2316192786452127GUERRA, Rosane Nassar Meireleshttp://lattes.cnpq.br/2316192786452127BRANCO, Maria dos Remédios Freitas Carvalhohttp://lattes.cnpq.br/5449951869928014NASCIMENTO, Johnny Ramos dohttp://lattes.cnpq.br/8835152858874648ARAGÃO, Mônica Virginia Viégas Lima dehttp://lattes.cnpq.br/2052899976995482SILVA, Mayara Cristina Pintohttp://lattes.cnpq.br/9507590466760552http://lattes.cnpq.br/0650397814124633CUNHA, Cláudia Regina Silva dos Santos2023-09-13T17:19:36Z2023-08-24CUNHA, Cláudia Regina Silva dos Santos. Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19. 2023. 101 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís, 2023.https://tedebc.ufma.br/jspui/handle/tede/tede/4942The present work delimited about the immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the COVID-19 pandemic. The methodology was guided by a systematic literature review and cross-sectional observational studies that resulted in the chapters presented in this thesis. With this study, it was possible to observe that the immunological interferences of COVID-19 infection in the body of the newborn are inconclusive. However, positive correlations were found between maternal COVID-19 infection and the levels of erythrocytes, hematocrit, hemoglobin, basophils, calcium and potassium of the newborn. It was possible to infer that the main interruptions of pregnancies before and during the COVID-19 pandemic occurred mainly due to cardiovascular complications evidenced by predisposing factors such as plateletosis, anemia and vascular resistance. And that prematurity is the main factor for hospitalization of neonates in intensive care units regardless of whether public or private service is provided. Thus, with this study, it is concluded that follow up studies are important for further evaluation of the repercussion of COVID-19 infection on the infant immune system, including the possibility of including evaluations of complete blood counts and biochemistry of these children at the time of collection of the foot test.O presente trabalho delimitou acerca do perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da COVID-19. A metodologia foi orientada por uma revisão de literatura sistemática e estudos observacionais do tipo transversal que resultaram nos capítulos apresentados nessa tese. Com esse estudo foi possível observar que são inconclusivas as interferências imunológicas da infecção pela COVID-19 no organismo dos nenonatos. No entanto, constatou-se correlações positivas entre a infecção materna por COVID-19 e o hematócrito, os números de eritrócitos e basófilos, os percentuais de hemoglobina e as concnetrações de cálcio e potássio do recém- nascido. Os resultados motraram que as principais causa de interrupções das gestações antes e durante a pandemia da COVID-19 ocorreram por complicações cardiovasculares decorrentes de fatores predisponentes como plaquetose, anemia e resistência vascular. Os dados mostraram também que a prematuridade foi a principal causa de internação dos neonatos em unidades de terapias intensivas, tanto no serviço público como no privado. Assim, foi possivel concluir que os estudos de follow up, de longa duração, são importantes para posterior avaliação da repercussão da COVID-19 sobre o sistema imune infantil e também que é importante incluir os exames bioquimicos e o hemogramas na rotina nos recém-nascidos, o que pode inclusive ocorrer durante a coleta para realização do teste do pezinho.Submitted by Jonathan Sousa de Almeida (jonathan.sousa@ufma.br) on 2023-09-13T17:19:36Z No. of bitstreams: 1 CLÁUDIAREGINASILVADOSSANTOSCUNHA.pdf: 1768055 bytes, checksum: 593d34ad8e3315fe1c05eab93f1e4244 (MD5)Made available in DSpace on 2023-09-13T17:19:36Z (GMT). No. of bitstreams: 1 CLÁUDIAREGINASILVADOSSANTOSCUNHA.pdf: 1768055 bytes, checksum: 593d34ad8e3315fe1c05eab93f1e4244 (MD5) Previous issue date: 2023-08-24FAPEMACAPESapplication/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBSUFMABrasilDEPARTAMENTO DE BIOLOGIA/CCBSCOVID-19;anticorpos;neonatos;leite materno;hemograma.COVID-19;antibodies;newborn;breast Milk;blood count.Saúde Materno-InfantilCiências da SaúdePerfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19Immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the covid-19 pandemicinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMAORIGINALCLÁUDIAREGINASILVADOSSANTOSCUNHA.pdfCLÁUDIAREGINASILVADOSSANTOSCUNHA.pdfapplication/pdf1768055http://tedebc.ufma.br:8080/bitstream/tede/4942/2/CL%C3%81UDIAREGINASILVADOSSANTOSCUNHA.pdf593d34ad8e3315fe1c05eab93f1e4244MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82255http://tedebc.ufma.br:8080/bitstream/tede/4942/1/license.txt97eeade1fce43278e63fe063657f8083MD51tede/49422023-09-13 14:19:36.603oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttps://tedebc.ufma.br/jspui/PUBhttp://tedebc.ufma.br:8080/oai/requestrepositorio@ufma.br||repositorio@ufma.bropendoar:21312023-09-13T17:19:36Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA)false |
dc.title.por.fl_str_mv |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
dc.title.alternative.eng.fl_str_mv |
Immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the covid-19 pandemic |
title |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
spellingShingle |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 CUNHA, Cláudia Regina Silva dos Santos COVID-19; anticorpos; neonatos; leite materno; hemograma. COVID-19; antibodies; newborn; breast Milk; blood count. Saúde Materno-Infantil Ciências da Saúde |
title_short |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
title_full |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
title_fullStr |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
title_full_unstemmed |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
title_sort |
Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19 |
author |
CUNHA, Cláudia Regina Silva dos Santos |
author_facet |
CUNHA, Cláudia Regina Silva dos Santos |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
GUERRA, Rosane Nassar Meireles |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/2316192786452127 |
dc.contributor.referee1.fl_str_mv |
GUERRA, Rosane Nassar Meireles |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/2316192786452127 |
dc.contributor.referee2.fl_str_mv |
BRANCO, Maria dos Remédios Freitas Carvalho |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/5449951869928014 |
dc.contributor.referee3.fl_str_mv |
NASCIMENTO, Johnny Ramos do |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/8835152858874648 |
dc.contributor.referee4.fl_str_mv |
ARAGÃO, Mônica Virginia Viégas Lima de |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/2052899976995482 |
dc.contributor.referee5.fl_str_mv |
SILVA, Mayara Cristina Pinto |
dc.contributor.referee5Lattes.fl_str_mv |
http://lattes.cnpq.br/9507590466760552 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0650397814124633 |
dc.contributor.author.fl_str_mv |
CUNHA, Cláudia Regina Silva dos Santos |
contributor_str_mv |
GUERRA, Rosane Nassar Meireles GUERRA, Rosane Nassar Meireles BRANCO, Maria dos Remédios Freitas Carvalho NASCIMENTO, Johnny Ramos do ARAGÃO, Mônica Virginia Viégas Lima de SILVA, Mayara Cristina Pinto |
dc.subject.por.fl_str_mv |
COVID-19; anticorpos; neonatos; leite materno; hemograma. |
topic |
COVID-19; anticorpos; neonatos; leite materno; hemograma. COVID-19; antibodies; newborn; breast Milk; blood count. Saúde Materno-Infantil Ciências da Saúde |
dc.subject.eng.fl_str_mv |
COVID-19; antibodies; newborn; breast Milk; blood count. |
dc.subject.cnpq.fl_str_mv |
Saúde Materno-Infantil Ciências da Saúde |
description |
The present work delimited about the immunological, hematological, biochemical and sociodemographic profile of pregnant women, puerperal women and newborns before and during the COVID-19 pandemic. The methodology was guided by a systematic literature review and cross-sectional observational studies that resulted in the chapters presented in this thesis. With this study, it was possible to observe that the immunological interferences of COVID-19 infection in the body of the newborn are inconclusive. However, positive correlations were found between maternal COVID-19 infection and the levels of erythrocytes, hematocrit, hemoglobin, basophils, calcium and potassium of the newborn. It was possible to infer that the main interruptions of pregnancies before and during the COVID-19 pandemic occurred mainly due to cardiovascular complications evidenced by predisposing factors such as plateletosis, anemia and vascular resistance. And that prematurity is the main factor for hospitalization of neonates in intensive care units regardless of whether public or private service is provided. Thus, with this study, it is concluded that follow up studies are important for further evaluation of the repercussion of COVID-19 infection on the infant immune system, including the possibility of including evaluations of complete blood counts and biochemistry of these children at the time of collection of the foot test. |
publishDate |
2023 |
dc.date.accessioned.fl_str_mv |
2023-09-13T17:19:36Z |
dc.date.issued.fl_str_mv |
2023-08-24 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CUNHA, Cláudia Regina Silva dos Santos. Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19. 2023. 101 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís, 2023. |
dc.identifier.uri.fl_str_mv |
https://tedebc.ufma.br/jspui/handle/tede/tede/4942 |
identifier_str_mv |
CUNHA, Cláudia Regina Silva dos Santos. Perfil imunológico, hematológico, bioquímico e sociodemográfico de gestantes, puérperas e recém-nascidos antes e durante a pandemia da covid-19. 2023. 101 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís, 2023. |
url |
https://tedebc.ufma.br/jspui/handle/tede/tede/4942 |
dc.language.iso.fl_str_mv |
por |
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por |
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openAccess |
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Universidade Federal do Maranhão |
dc.publisher.program.fl_str_mv |
PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBS |
dc.publisher.initials.fl_str_mv |
UFMA |
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Brasil |
dc.publisher.department.fl_str_mv |
DEPARTAMENTO DE BIOLOGIA/CCBS |
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Universidade Federal do Maranhão |
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