Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva

Detalhes bibliográficos
Autor(a) principal: CARMO, Reivax Silva do
Data de Publicação: 2024
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFMA
Texto Completo: https://tedebc.ufma.br/jspui/handle/tede/tede/5350
Resumo: Introduction: Introduction: Cancer represents a serious public health problem in Brazil, where more than half of patients are diagnosed at an advanced stage of the disease. The rationalization of therapeutic measures must take pride of place in the follow-up of these patients, since prolonging the process of death that has already begun can generate unnecessary suffering. The objective of this study is to evaluate invasive interventions performed on patients with advanced cancer admitted to the ICU. Methodology: Observational, cross-sectional study, with a quantitative approach, carried out with patients with advanced cancer and admitted to ICUs of oncology hospitals, in the State of Maranhão. The Supportive And Palliative Care Indicators (SPCIT) scales were used to evaluate the indication for PC, Eastern Cooperative Oncologic Group/Karnofsky Performance (ECOG/KPS) and Charlson Comorbidity Index (CCI) to evaluate severity, description of procedures invasive procedures carried out and application of the surprise question. The association between the data obtained was tested using the chi-square test, logistic regression, Poisson regression and survival curve. Results: The main characteristics found in this sample were: the majority of adults/elderly, gynecological cancer (22.7%), gastrointestinal tract (22.7%) and breast (13.8%), with metastasis (90.0% ), palliative chemotherapy (65.3%), positive SPICT (99.0%), severe with KPS/ECOG score 4 (61.0%) and ICC score 6 (93.0%), with 85, 0% “No” response to the surprise question and association of significance with the death outcome, in addition to being without PC monitoring (96.0%) and without directives of wishes (99.0%). Indwelling urinary catheter (SVD), central venous access (CVC), mechanical ventilation (MV) and vasoactive drug (VAD) were the most commonly performed invasive procedures, with SVD as a protective factor and odds ratio (OR) of 0.23 and MV as a risk factor and OR of 3.39 for death. In the Poisson regression, MV presented a prevalence ratio (PR) of 197.0% and DVA of 162.0% for the outcome death. The average hospitalization of patients was 10.3 days and 54.5% died. Conclusions: It is concluded that patients with advanced, metastatic cancer, with eligibility criteria for PC, considered serious, were referred to the ICU and underwent invasive procedures such as SVD, CVC, DVA, MV and even so, 54.5% died within a few days of hospitalization. In addition, no evaluation/monitoring was requested by the CP team.
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spelling GARCIA, João Batista Santoshttp://lattes.cnpq.br/0424234103760462GARCIA, João Batista Santoshttp://lattes.cnpq.br/0424234103760462BARBOSA NETO, José Osvaldohttp://lattes.cnpq.br/6959740813304610NASCIMENTO, Maria do Desterro Soares Brandaohttp://lattes.cnpq.br/3958174822396319RODRIGUES, Thiago Alveshttp://lattes.cnpq.br/3694330594230199http://lattes.cnpq.br/8090436719122594CARMO, Reivax Silva do2024-06-14T11:36:44Z2024-04-29CARMO, Reivax Silva do. Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva. 2024. 67 f. Dissertação (Programa de Pós-Graduação em Saúde do Adulto) - Universidade Federal do Maranhão, São Luís, 2024.https://tedebc.ufma.br/jspui/handle/tede/tede/5350Introduction: Introduction: Cancer represents a serious public health problem in Brazil, where more than half of patients are diagnosed at an advanced stage of the disease. The rationalization of therapeutic measures must take pride of place in the follow-up of these patients, since prolonging the process of death that has already begun can generate unnecessary suffering. The objective of this study is to evaluate invasive interventions performed on patients with advanced cancer admitted to the ICU. Methodology: Observational, cross-sectional study, with a quantitative approach, carried out with patients with advanced cancer and admitted to ICUs of oncology hospitals, in the State of Maranhão. The Supportive And Palliative Care Indicators (SPCIT) scales were used to evaluate the indication for PC, Eastern Cooperative Oncologic Group/Karnofsky Performance (ECOG/KPS) and Charlson Comorbidity Index (CCI) to evaluate severity, description of procedures invasive procedures carried out and application of the surprise question. The association between the data obtained was tested using the chi-square test, logistic regression, Poisson regression and survival curve. Results: The main characteristics found in this sample were: the majority of adults/elderly, gynecological cancer (22.7%), gastrointestinal tract (22.7%) and breast (13.8%), with metastasis (90.0% ), palliative chemotherapy (65.3%), positive SPICT (99.0%), severe with KPS/ECOG score 4 (61.0%) and ICC score 6 (93.0%), with 85, 0% “No” response to the surprise question and association of significance with the death outcome, in addition to being without PC monitoring (96.0%) and without directives of wishes (99.0%). Indwelling urinary catheter (SVD), central venous access (CVC), mechanical ventilation (MV) and vasoactive drug (VAD) were the most commonly performed invasive procedures, with SVD as a protective factor and odds ratio (OR) of 0.23 and MV as a risk factor and OR of 3.39 for death. In the Poisson regression, MV presented a prevalence ratio (PR) of 197.0% and DVA of 162.0% for the outcome death. The average hospitalization of patients was 10.3 days and 54.5% died. Conclusions: It is concluded that patients with advanced, metastatic cancer, with eligibility criteria for PC, considered serious, were referred to the ICU and underwent invasive procedures such as SVD, CVC, DVA, MV and even so, 54.5% died within a few days of hospitalization. In addition, no evaluation/monitoring was requested by the CP team.Introdução: O câncer representa um grave problema de saúde pública no Brasil, onde mais da metade dos pacientes são diagnosticados em estágio avançado da doença. A racionalização de medidas terapêuticas deve tomar lugar de destaque no seguimento destes pacientes, uma vez que prolongar o processo já iniciado de morte pode gerar sofrimento desnecessário. O objetivo deste estudo é avaliar as intervenções invasivas realizadas em pacientes com câncer avançado internados em UTI. Metodologia: Estudo observacional, transversal, com abordagem quantitativa, realizada com pacientes portadores de câncer avançado e internados em UTIs de hospitais oncológicos, no Estado do Maranhão. Foram utilizadas as escalas de Supportive And Palliative Care Indicators (SPCIT) para avaliar a indicação de CP, Eastern Cooperative Oncologic Group/Performace de Karnofsky (ECOG/KPS) e Índice de Comorbidade de Charlson (ICC) para avaliação da gravidade, descrição dos procedimentos invasivos realizados e aplicação da pergunta surpresa. A associação entre os dados obtidos foi testada através dos testes de qui-quadrado, regressão logística, regressão de Poisson e curva de sobrevivência. Resultados: As principais características encontradas nessa amostra foram: a maioria de adultos/idosos, câncer ginecológico (22,7%), trato gastrointestinal (22,7%) e mama (13,8%), com metástase (90,0%), quimioterapia paliativa (65,3%), SPICT positivo (99,0%), graves com escore 4 de KPS/ECOG (61,0%) e com escore 6 no ICC (93,0%), com 85,0% de resposta “Não” para a pergunta surpresa e associação de significância com o desfecho óbito, além de estarem sem acompanhamento dos CP (96,0%) e sem diretivas de vontades (99,0%). Sonda vesical de demora (SVD), acesso venoso central (CVC), ventilação mecânica (VM) e droga vasoativa (DVA) foram os procedimentos invasivos mais realizados, com SVD como fator de proteção e razão de chance (OR) de 0,23 e VM como fator de risco e OR de 3,39 para óbito. Na regressão de Poisson a VM apresentou uma razão de prevalência (RP) de 197,0% e DVA de 162,0% para o desfecho óbito. A média de internação dos pacientes foi de 10,3 dias e 54,5% evoluíram para óbito. Conclusões: Conclui-se que os pacientes com câncer avançado, metastático, com critérios de elegibilidade para CP, considerados graves foram encaminhados a UTI e submetidos a procedimentos invasivos como SVD, CVC, DVA, VM e mesmo assim 54,5% evoluíram a óbito em poucos dias de internação. Além de não ter sido solicitado avaliação/acompanhamento pela equipe de CP.Submitted by Jonathan Sousa de Almeida (jonathan.sousa@ufma.br) on 2024-06-14T11:36:44Z No. of bitstreams: 1 REIVAXSILVADOCARMO.pdf: 1725508 bytes, checksum: c4731cf2649df74849ad3a0029e9f872 (MD5)Made available in DSpace on 2024-06-14T11:36:44Z (GMT). No. of bitstreams: 1 REIVAXSILVADOCARMO.pdf: 1725508 bytes, checksum: c4731cf2649df74849ad3a0029e9f872 (MD5) Previous issue date: 2024-04-29application/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE DO ADULTOUFMABrasilDEPARTAMENTO DE MEDICINA II/CCBSneoplasias;cuidados paliativos;Unidades de Terapia Intensiva.neoplasms;palliative care;Intensive Care Units.CancerologiaCiências da SaúdeMedidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensivaInvasive Measures Performed in Patients With Advanced Cancer Under Care palliatives in intensive careinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMAORIGINALREIVAXSILVADOCARMO.pdfREIVAXSILVADOCARMO.pdfapplication/pdf1725508http://tedebc.ufma.br:8080/bitstream/tede/5350/2/REIVAXSILVADOCARMO.pdfc4731cf2649df74849ad3a0029e9f872MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82255http://tedebc.ufma.br:8080/bitstream/tede/5350/1/license.txt97eeade1fce43278e63fe063657f8083MD51tede/53502024-06-14 08:36:44.389oai:tede2:tede/5350Biblioteca Digital de Teses e Dissertaçõeshttps://tedebc.ufma.br/jspui/PUBhttp://tedebc.ufma.br:8080/oai/requestrepositorio@ufma.br||repositorio@ufma.bropendoar:21312024-06-14T11:36:44Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA)false
dc.title.por.fl_str_mv Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
dc.title.alternative.eng.fl_str_mv Invasive Measures Performed in Patients With Advanced Cancer Under Care palliatives in intensive care
title Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
spellingShingle Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
CARMO, Reivax Silva do
neoplasias;
cuidados paliativos;
Unidades de Terapia Intensiva.
neoplasms;
palliative care;
Intensive Care Units.
Cancerologia
Ciências da Saúde
title_short Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
title_full Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
title_fullStr Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
title_full_unstemmed Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
title_sort Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva
author CARMO, Reivax Silva do
author_facet CARMO, Reivax Silva do
author_role author
dc.contributor.advisor1.fl_str_mv GARCIA, João Batista Santos
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/0424234103760462
dc.contributor.referee1.fl_str_mv GARCIA, João Batista Santos
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/0424234103760462
dc.contributor.referee2.fl_str_mv BARBOSA NETO, José Osvaldo
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/6959740813304610
dc.contributor.referee3.fl_str_mv NASCIMENTO, Maria do Desterro Soares Brandao
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/3958174822396319
dc.contributor.referee4.fl_str_mv RODRIGUES, Thiago Alves
dc.contributor.referee4Lattes.fl_str_mv http://lattes.cnpq.br/3694330594230199
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/8090436719122594
dc.contributor.author.fl_str_mv CARMO, Reivax Silva do
contributor_str_mv GARCIA, João Batista Santos
GARCIA, João Batista Santos
BARBOSA NETO, José Osvaldo
NASCIMENTO, Maria do Desterro Soares Brandao
RODRIGUES, Thiago Alves
dc.subject.por.fl_str_mv neoplasias;
cuidados paliativos;
Unidades de Terapia Intensiva.
topic neoplasias;
cuidados paliativos;
Unidades de Terapia Intensiva.
neoplasms;
palliative care;
Intensive Care Units.
Cancerologia
Ciências da Saúde
dc.subject.eng.fl_str_mv neoplasms;
palliative care;
Intensive Care Units.
dc.subject.cnpq.fl_str_mv Cancerologia
Ciências da Saúde
description Introduction: Introduction: Cancer represents a serious public health problem in Brazil, where more than half of patients are diagnosed at an advanced stage of the disease. The rationalization of therapeutic measures must take pride of place in the follow-up of these patients, since prolonging the process of death that has already begun can generate unnecessary suffering. The objective of this study is to evaluate invasive interventions performed on patients with advanced cancer admitted to the ICU. Methodology: Observational, cross-sectional study, with a quantitative approach, carried out with patients with advanced cancer and admitted to ICUs of oncology hospitals, in the State of Maranhão. The Supportive And Palliative Care Indicators (SPCIT) scales were used to evaluate the indication for PC, Eastern Cooperative Oncologic Group/Karnofsky Performance (ECOG/KPS) and Charlson Comorbidity Index (CCI) to evaluate severity, description of procedures invasive procedures carried out and application of the surprise question. The association between the data obtained was tested using the chi-square test, logistic regression, Poisson regression and survival curve. Results: The main characteristics found in this sample were: the majority of adults/elderly, gynecological cancer (22.7%), gastrointestinal tract (22.7%) and breast (13.8%), with metastasis (90.0% ), palliative chemotherapy (65.3%), positive SPICT (99.0%), severe with KPS/ECOG score 4 (61.0%) and ICC score 6 (93.0%), with 85, 0% “No” response to the surprise question and association of significance with the death outcome, in addition to being without PC monitoring (96.0%) and without directives of wishes (99.0%). Indwelling urinary catheter (SVD), central venous access (CVC), mechanical ventilation (MV) and vasoactive drug (VAD) were the most commonly performed invasive procedures, with SVD as a protective factor and odds ratio (OR) of 0.23 and MV as a risk factor and OR of 3.39 for death. In the Poisson regression, MV presented a prevalence ratio (PR) of 197.0% and DVA of 162.0% for the outcome death. The average hospitalization of patients was 10.3 days and 54.5% died. Conclusions: It is concluded that patients with advanced, metastatic cancer, with eligibility criteria for PC, considered serious, were referred to the ICU and underwent invasive procedures such as SVD, CVC, DVA, MV and even so, 54.5% died within a few days of hospitalization. In addition, no evaluation/monitoring was requested by the CP team.
publishDate 2024
dc.date.accessioned.fl_str_mv 2024-06-14T11:36:44Z
dc.date.issued.fl_str_mv 2024-04-29
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identifier_str_mv CARMO, Reivax Silva do. Medidas invasivas realizadas em pacientes com câncer avançado em cuidados paliativos em terapia intensiva. 2024. 67 f. Dissertação (Programa de Pós-Graduação em Saúde do Adulto) - Universidade Federal do Maranhão, São Luís, 2024.
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dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv DEPARTAMENTO DE MEDICINA II/CCBS
publisher.none.fl_str_mv Universidade Federal do Maranhão
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