Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®.
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFMA |
Texto Completo: | https://tedebc.ufma.br/jspui/handle/tede/tede/3183 |
Resumo: | An in vitro and in vivo study with an experimental endodontic repair cement containing 45S5 bioactive glass was conducted. There were three endodontic repair cement groups: 45S5 bioactive glass-based (BioG), zinc oxide-based (ZnO), and Mineral Trioxide Aggregate (MTA). In vitro tests were used to evaluate their physicochemical properties: compressive strength, modulus of elasticity, radiopacity, pH variation, and the ionic release of Ca+ and PO4. An animal model was used to evaluate the bone tissue response to endodontic repair cement. Comparisons employed an unpaired t-test or ANOVA and Tukey’s test ( = 5%). BioG showed the lowest compressive strength and ZnO showed the highest radiopacity among the groups, respectively (p < 0.05). There were no significant differences in the modulus of elasticity among the groups. BioG and MTA maintained an alkaline pH during the 7 days of evaluation, both at pH 4 and in a pH 7 buffered solutions. PO4 was elevated in BioG, peaking at 7 days (p < 0.05). Histological analysis showed less intense inflammatory reactions and new bone formation in MTA. BioG showed inflammatory reactions that decreased over time. The BioG experimental cement had good physicochemical characteristics and biocompatibility required for bioactive endodontic repair cement. |
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SOUZA, Soraia de Fátima Carvalho251904903-00http://lattes.cnpq.br/0042423903693579PASCHOAL, Marco Aurélio Beninihttp://lattes.cnpq.br/0894826377506478ABREU JUNIOR, Afonso Gomeshttp://lattes.cnpq.br/4394413983541820CONDE, Daniele Meirahttp://lattes.cnpq.br/6988763738175457LIMA, Darlon Martinshttp://lattes.cnpq.br/9472478898441292SOUZA, Soraia de Fátima Carvalhohttp://lattes.cnpq.br/0042423903693579037728393-20http://lattes.cnpq.br/1670290503929001Michael Ranniery Garcia RIBEIRO2021-02-11T13:50:45Z2018-02-26Michael Ranniery Garcia RIBEIRO. Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. 2018. 75 f. Tese (Programa de Pós-Graduação em Odontologia/CCBS) - Universidade Federal do Maranhão, São Luís, 2018.https://tedebc.ufma.br/jspui/handle/tede/tede/3183An in vitro and in vivo study with an experimental endodontic repair cement containing 45S5 bioactive glass was conducted. There were three endodontic repair cement groups: 45S5 bioactive glass-based (BioG), zinc oxide-based (ZnO), and Mineral Trioxide Aggregate (MTA). In vitro tests were used to evaluate their physicochemical properties: compressive strength, modulus of elasticity, radiopacity, pH variation, and the ionic release of Ca+ and PO4. An animal model was used to evaluate the bone tissue response to endodontic repair cement. Comparisons employed an unpaired t-test or ANOVA and Tukey’s test ( = 5%). BioG showed the lowest compressive strength and ZnO showed the highest radiopacity among the groups, respectively (p < 0.05). There were no significant differences in the modulus of elasticity among the groups. BioG and MTA maintained an alkaline pH during the 7 days of evaluation, both at pH 4 and in a pH 7 buffered solutions. PO4 was elevated in BioG, peaking at 7 days (p < 0.05). Histological analysis showed less intense inflammatory reactions and new bone formation in MTA. BioG showed inflammatory reactions that decreased over time. The BioG experimental cement had good physicochemical characteristics and biocompatibility required for bioactive endodontic repair cement.Foi conduzido um estudo in viro e in vivo com um cimento experimental de reparo endodôntico contendo vidro bioativo 45S5. Foram testados três grupos de cimento de reparo endodôntico: À base de vidro bioativo 45S5 (BioG), à base de óxido de zinco (ZnO) e agregado de trióxido mineral (MTA). Testes in vitro foram utilizados para avaliar suas propriedades físico-químicas: resistência à compressão, módulo de elasticidade, radiopacidade, variação do pH e liberação iônica de Ca+ e PO4. Um modelo animal foi usado para avaliar a resposta do tecido ósseo ao cimento de reparo endodôntico. Empregou-se na avaliação estatística o teste t não pareado ou ANOVA e teste de Tukey (α= 5%). O BioG apresentou a menor resistência à compressão e o ZnO a maior radiopacidade entre os grupos, respectivamente (p < 0,05). Não houve diferenças significativas no módulo de elasticidade entre os grupos. BioG e MTA mantiveram pH alcalino durante os 7 dias de avaliação, tanto em pH 4 quanto em solução tamponada de pH 7. A liberação de PO4 foi elevado no BioG, com pico em 7 dias (p < 0,05). A análise histológica mostrou reações inflamatórias menos intensas e neoformação óssea no MTA. O BioG mostrou reações inflamatórias que diminuíram com o tempo. O cimento experimental BioG apresentou boas características físico-químicas e biocompatibilidade necessária para o cimento endodôntico de reparo bioativo.Submitted by Daniella Santos (daniella.santos@ufma.br) on 2021-02-11T13:50:45Z No. of bitstreams: 1 MICHAELRIBEIRO.pdf: 782719 bytes, checksum: 4ded66b782bd26cb20eba739836684ec (MD5)Made available in DSpace on 2021-02-11T13:50:45Z (GMT). No. of bitstreams: 1 MICHAELRIBEIRO.pdf: 782719 bytes, checksum: 4ded66b782bd26cb20eba739836684ec (MD5) Previous issue date: 2018-02-26application/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM ODONTOLOGIA/CCBSUFMABrasilDEPARTAMENTO DE ODONTOLOGIA I/CCBSBiovidroEndodontiaHistológicoMTAReabsorção RadicularHistologicalBioglassEndodonticsMTARoot resorptionOdontologiaAnálise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®.Physico-chemical and histological analysis of an experimental endodontic repair cement based on 45S5® bioglass.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMAORIGINALMICHAELRIBEIRO.pdfMICHAELRIBEIRO.pdfapplication/pdf782719http://tedebc.ufma.br:8080/bitstream/tede/3183/2/MICHAELRIBEIRO.pdf4ded66b782bd26cb20eba739836684ecMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82255http://tedebc.ufma.br:8080/bitstream/tede/3183/1/license.txt97eeade1fce43278e63fe063657f8083MD51tede/31832021-02-11 10:50:45.158oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttps://tedebc.ufma.br/jspui/PUBhttp://tedebc.ufma.br:8080/oai/requestrepositorio@ufma.br||repositorio@ufma.bropendoar:21312021-02-11T13:50:45Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA)false |
dc.title.por.fl_str_mv |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
dc.title.alternative.eng.fl_str_mv |
Physico-chemical and histological analysis of an experimental endodontic repair cement based on 45S5® bioglass. |
title |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
spellingShingle |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. Michael Ranniery Garcia RIBEIRO Biovidro Endodontia Histológico MTA Reabsorção Radicular Histological Bioglass Endodontics MTA Root resorption Odontologia |
title_short |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
title_full |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
title_fullStr |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
title_full_unstemmed |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
title_sort |
Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. |
author |
Michael Ranniery Garcia RIBEIRO |
author_facet |
Michael Ranniery Garcia RIBEIRO |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
SOUZA, Soraia de Fátima Carvalho |
dc.contributor.advisor1ID.fl_str_mv |
251904903-00 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/0042423903693579 |
dc.contributor.referee1.fl_str_mv |
PASCHOAL, Marco Aurélio Benini |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/0894826377506478 |
dc.contributor.referee2.fl_str_mv |
ABREU JUNIOR, Afonso Gomes |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/4394413983541820 |
dc.contributor.referee3.fl_str_mv |
CONDE, Daniele Meira |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/6988763738175457 |
dc.contributor.referee4.fl_str_mv |
LIMA, Darlon Martins |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/9472478898441292 |
dc.contributor.referee5.fl_str_mv |
SOUZA, Soraia de Fátima Carvalho |
dc.contributor.referee5Lattes.fl_str_mv |
http://lattes.cnpq.br/0042423903693579 |
dc.contributor.authorID.fl_str_mv |
037728393-20 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/1670290503929001 |
dc.contributor.author.fl_str_mv |
Michael Ranniery Garcia RIBEIRO |
contributor_str_mv |
SOUZA, Soraia de Fátima Carvalho PASCHOAL, Marco Aurélio Benini ABREU JUNIOR, Afonso Gomes CONDE, Daniele Meira LIMA, Darlon Martins SOUZA, Soraia de Fátima Carvalho |
dc.subject.por.fl_str_mv |
Biovidro Endodontia Histológico MTA Reabsorção Radicular Histological |
topic |
Biovidro Endodontia Histológico MTA Reabsorção Radicular Histological Bioglass Endodontics MTA Root resorption Odontologia |
dc.subject.eng.fl_str_mv |
Bioglass Endodontics MTA Root resorption |
dc.subject.cnpq.fl_str_mv |
Odontologia |
description |
An in vitro and in vivo study with an experimental endodontic repair cement containing 45S5 bioactive glass was conducted. There were three endodontic repair cement groups: 45S5 bioactive glass-based (BioG), zinc oxide-based (ZnO), and Mineral Trioxide Aggregate (MTA). In vitro tests were used to evaluate their physicochemical properties: compressive strength, modulus of elasticity, radiopacity, pH variation, and the ionic release of Ca+ and PO4. An animal model was used to evaluate the bone tissue response to endodontic repair cement. Comparisons employed an unpaired t-test or ANOVA and Tukey’s test ( = 5%). BioG showed the lowest compressive strength and ZnO showed the highest radiopacity among the groups, respectively (p < 0.05). There were no significant differences in the modulus of elasticity among the groups. BioG and MTA maintained an alkaline pH during the 7 days of evaluation, both at pH 4 and in a pH 7 buffered solutions. PO4 was elevated in BioG, peaking at 7 days (p < 0.05). Histological analysis showed less intense inflammatory reactions and new bone formation in MTA. BioG showed inflammatory reactions that decreased over time. The BioG experimental cement had good physicochemical characteristics and biocompatibility required for bioactive endodontic repair cement. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-02-26 |
dc.date.accessioned.fl_str_mv |
2021-02-11T13:50:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Michael Ranniery Garcia RIBEIRO. Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. 2018. 75 f. Tese (Programa de Pós-Graduação em Odontologia/CCBS) - Universidade Federal do Maranhão, São Luís, 2018. |
dc.identifier.uri.fl_str_mv |
https://tedebc.ufma.br/jspui/handle/tede/tede/3183 |
identifier_str_mv |
Michael Ranniery Garcia RIBEIRO. Análise físico-química e histológica de um cimento de reparo endodôntico experimental à base de bioglass 45S5®. 2018. 75 f. Tese (Programa de Pós-Graduação em Odontologia/CCBS) - Universidade Federal do Maranhão, São Luís, 2018. |
url |
https://tedebc.ufma.br/jspui/handle/tede/tede/3183 |
dc.language.iso.fl_str_mv |
por |
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por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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dc.publisher.none.fl_str_mv |
Universidade Federal do Maranhão |
dc.publisher.program.fl_str_mv |
PROGRAMA DE PÓS-GRADUAÇÃO EM ODONTOLOGIA/CCBS |
dc.publisher.initials.fl_str_mv |
UFMA |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
DEPARTAMENTO DE ODONTOLOGIA I/CCBS |
publisher.none.fl_str_mv |
Universidade Federal do Maranhão |
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