Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFMA |
Texto Completo: | https://tedebc.ufma.br/jspui/handle/tede/tede/4275 |
Resumo: | Patients undergoing cardiac surgery may present functional changes in the postoperative period. Several physiotherapeutic interventions have been described aiming to minimize the functional loss related to the surgical procedure. However, they present as a limitation the use of generalist protocols that are not based on the individuality of patients. Thus, this research proposes to verify the effects of the application of an adapted mobilization protocol, based on the functional level, on mobility, peripheral muscle strength, length of stay in the Intensive Care Unit (ICU) and hospital of patients undergoing cardiac surgery. We conducted a randomized controlled trial with adult patients (18 to 60 years old), of both sexes, who underwent cardiac surgery from January 2020 to June 2021. Patients were evaluated regarding: (i) time, in hours, to achieve mobilization milestones (bedside sitting, out of bed sitting, standing and walking); (ii) level of mobility, using the ICU Mobility Scale (IMS); (iii) peripheral muscle strength, using hand grip dynamometry; and (iv) length of stay in the ICU and hospital. Participants were randomized into two groups: a control group (conventional mobilization protocol) and an intervention group (functional level-based mobilization protocol). The intervention protocol was adapted from the study by Hodgson et al. (2016), based on the IMS level, and the conventional protocol, as recommended by Winkelmann et al. (2015). In chapter 1, we provide, through a systematic review, the description of exercise prescription in patients undergoing cardiac surgery. In conclusion, most protocols are generalist, progressive, low intensity, with frequency of twice a day and duration of 10 to 30 minutes. In chapter II, the impact of an individualized protocol on the mobility of patients undergoing cardiac surgery compared to the conventional protocol was evaluated. No statistically significant differences were found in the two types of protocol regarding mobilization milestones and mobility level, peripheral muscle strength, length of stay in the Intensive Care Unit (ICU) and hospital comparing the protocols. |
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NINA, Vinicius José da Silva Ninahttp://lattes.cnpq.br/5148313598301706BORGES, Daniel Lagohttp://lattes.cnpq.br/0732282114720827DIBAI, Daniela Bassihttp://lattes.cnpq.br/0861598490954598MONTEIRO, Silvio Gomeshttp://lattes.cnpq.br/1682966336184874SIQUEIRA FILHO, Mário Alves dehttp://lattes.cnpq.br/4816046653397785REGO, Adriana Sousahttp://lattes.cnpq.br/7001225083239682http://lattes.cnpq.br/3992896109526229BORGES, Mayara Gabrielle Barbosa2022-11-07T17:24:20Z2022-06-15BORGES, Mayara Gabrielle Barbosa. Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado. 2022. 89 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís.https://tedebc.ufma.br/jspui/handle/tede/tede/4275Patients undergoing cardiac surgery may present functional changes in the postoperative period. Several physiotherapeutic interventions have been described aiming to minimize the functional loss related to the surgical procedure. However, they present as a limitation the use of generalist protocols that are not based on the individuality of patients. Thus, this research proposes to verify the effects of the application of an adapted mobilization protocol, based on the functional level, on mobility, peripheral muscle strength, length of stay in the Intensive Care Unit (ICU) and hospital of patients undergoing cardiac surgery. We conducted a randomized controlled trial with adult patients (18 to 60 years old), of both sexes, who underwent cardiac surgery from January 2020 to June 2021. Patients were evaluated regarding: (i) time, in hours, to achieve mobilization milestones (bedside sitting, out of bed sitting, standing and walking); (ii) level of mobility, using the ICU Mobility Scale (IMS); (iii) peripheral muscle strength, using hand grip dynamometry; and (iv) length of stay in the ICU and hospital. Participants were randomized into two groups: a control group (conventional mobilization protocol) and an intervention group (functional level-based mobilization protocol). The intervention protocol was adapted from the study by Hodgson et al. (2016), based on the IMS level, and the conventional protocol, as recommended by Winkelmann et al. (2015). In chapter 1, we provide, through a systematic review, the description of exercise prescription in patients undergoing cardiac surgery. In conclusion, most protocols are generalist, progressive, low intensity, with frequency of twice a day and duration of 10 to 30 minutes. In chapter II, the impact of an individualized protocol on the mobility of patients undergoing cardiac surgery compared to the conventional protocol was evaluated. No statistically significant differences were found in the two types of protocol regarding mobilization milestones and mobility level, peripheral muscle strength, length of stay in the Intensive Care Unit (ICU) and hospital comparing the protocols.Pacientes submetidos a cirurgia cardíaca podem apresentar alterações funcionais no período pós-operatório. Diversas intervenções fisioterapêuticas têm sido descritas com o intuito de minimizar a perda funcional relacionada ao procedimento cirúrgico. Entretanto apresentam como limitação a utilização de protocolos generalistas que não são baseados na individualidade dos pacientes. Dessa forma, essa pesquisa propõe-se verificar os efeitos da aplicação de um protocolo de mobilização adaptado, baseado no nível funcional, na mobilidade, força muscular periférica, tempo de estadia na Unidade de Terapia Intensiva (UTI) e hospitalar e tempo para alcance dos marcos de mobilização de pacientes submetidos à cirurgia cardíaca. Trata-se de um ensaio clínico controlado e randomizado. A amostra foi constituída por pacientes adultos (22 a 73 anos), de ambos os sexos, submetidos a cirurgia cardíaca, no período de janeiro de 2020 a junho 2021. Os pacientes foram avaliados quanto a: (i) tempo, em horas, para alcançar os marcos de mobilização (sedestação beira leito, sedestação fora do leito, ortostatismo e deambulação); (ii) nível de mobilidade, por meio da ICU Mobility Scale (IMS); (iii) força muscular periférica, por meio da dinamometria de mão; e (iv) tempo de estadia na UTI e hospitalar. Os participantes foram randomizados em dois grupos: grupo controle (protocolo de mobilização convencional) e o grupo intervenção (protocolo de mobilização baseado no nível funcional). O protocolo de intervenção foi adaptado do estudo de Hodgson et al. (2016), baseado no nível de IMS, e o protocolo convencional, conforme recomendado por Winkelmann et al. (2015). No capítulo 1, fornecemos por meio de revisão sistemática a descrição da prescrição de exercícios em pacientes submetidos a cirurgia cardíaca. Como conclusão, os protocolos na sua maioria são generalistas, progressivos e de baixa intensidade, com frequência de duas vezes por dia e duração de 10 a 30 minutos. No capítulo II, foi avaliado o impacto de um protocolo individualizado na mobilidade de pacientes submetidos a cirurgia cardíaca em comparação com o protocolo convencional. Não foram encontradas diferenças estatisticamente significativas nos dois tipos de protocolo quanto aos marcos de mobilização, nível de mobilidade, força muscular periférica e tempos de estadia na UTI e hospital ao comparar os protocolos.Submitted by Jonathan Sousa de Almeida (jonathan.sousa@ufma.br) on 2022-11-07T17:24:20Z No. of bitstreams: 1 MAYARAGABRIELLEBARBOSABORGES.pdf: 3418471 bytes, checksum: 28b13cb853fac02a402c54f4d3791c39 (MD5)Made available in DSpace on 2022-11-07T17:24:20Z (GMT). No. of bitstreams: 1 MAYARAGABRIELLEBARBOSABORGES.pdf: 3418471 bytes, checksum: 28b13cb853fac02a402c54f4d3791c39 (MD5) Previous issue date: 2022-06-15application/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBSUFMABrasilDEPARTAMENTO DE MEDICINA I/CCBSProcedimentos cirúrgicos cardiovasculares;Movimento;Força Muscular.Cardiovascular surgical procedures;Movement;Muscle strength.Cirurgia CardiovascularCiências da SaúdeAplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizadoApplication of a mobilization protocol, based on functional level, in patients submitted to cardiac surgery: controlled, randomized clinical trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMAORIGINALMAYARAGABRIELLEBARBOSABORGES.pdfMAYARAGABRIELLEBARBOSABORGES.pdfapplication/pdf3418471http://tedebc.ufma.br:8080/bitstream/tede/4275/2/MAYARAGABRIELLEBARBOSABORGES.pdf28b13cb853fac02a402c54f4d3791c39MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82255http://tedebc.ufma.br:8080/bitstream/tede/4275/1/license.txt97eeade1fce43278e63fe063657f8083MD51tede/42752022-11-08 08:18:07.841oai:tede2:tede/4275IExJQ0VOw4dBIERFIERJU1RSSUJVScOHw4NPIE7Dg08tRVhDTFVTSVZBCgpDb20gYSBhcHJlc2VudGHDp8OjbyBkZXN0YSBsaWNlbsOnYSxvIGF1dG9yIChlcykgb3UgbyB0aXR1bGFyIGRvcyBkaXJlaXRvcyBkZSBhdXRvciBjb25jZWRlIMOgIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRvIE1hcmFuaMOjbyAoVUZNQSkgbyBkaXJlaXRvIG7Do28tZXhjbHVzaXZvIGRlIHJlcHJvZHV6aXIsIHRyYWR1emlyIChjb25mb3JtZSBkZWZpbmlkbyBhYmFpeG8pLCBlL291IGRpc3RyaWJ1aXIgYSBzdWEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvIChpbmNsdWluZG8gbyByZXN1bW8pIHBvciB0b2RvIG8gbXVuZG8gbm8gZm9ybWF0byBpbXByZXNzbyBlIGVsZXRyw7RuaWNvIGUgZW0gcXVhbHF1ZXIgbWVpbywgaW5jbHVpbmRvIG9zIGZvcm1hdG9zIMOhdWRpbyBvdSB2w61kZW8uCgpWb2PDqiBjb25jb3JkYSBxdWUgYSBVRk1BIHBvZGUsIHNlbSBhbHRlcmFyIG8gY29udGXDumRvLCB0cmFuc3BvciBhIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gcGFyYSBxdWFscXVlciBtZWlvIG91IGZvcm1hdG8gcGFyYSBmaW5zIGRlIHByZXNlcnZhw6fDo28uCgpWb2PDqiB0YW1iw6ltIGNvbmNvcmRhIHF1ZSBhIFVGTUEgcG9kZSBtYW50ZXIgbWFpcyBkZSB1bWEgY8OzcGlhIGRlIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gcGFyYSBmaW5zIGRlIHNlZ3VyYW7Dp2EsIGJhY2stdXAgZSBwcmVzZXJ2YcOnw6NvLgoKVm9jw6ogZGVjbGFyYSBxdWUgYSBzdWEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvIMOpIG9yaWdpbmFsIGUgcXVlIHZvY8OqIHRlbSBvIHBvZGVyIGRlIGNvbmNlZGVyIG9zIGRpcmVpdG9zIGNvbnRpZG9zIG5lc3RhIGxpY2Vuw6dhLiBWb2PDqiB0YW1iw6ltIGRlY2xhcmEgcXVlIG8gZGVww7NzaXRvIGRhIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gbsOjbywgcXVlIHNlamEgZGUgc2V1IGNvbmhlY2ltZW50bywgaW5mcmluZ2UgZGlyZWl0b3MgYXV0b3JhaXMgZGUgbmluZ3XDqW0uCgpDYXNvIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyBjb250ZW5oYSBtYXRlcmlhbCBxdWUgdm9jw6ogbsOjbyBwb3NzdWkgYSB0aXR1bGFyaWRhZGUgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCB2b2PDqiBkZWNsYXJhIHF1ZSBvYnRldmUgYSBwZXJtaXNzw6NvIGlycmVzdHJpdGEgZG8gZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzIHBhcmEgY29uY2VkZXIgw6AgVUZNQSBvcyBkaXJlaXRvcyBhcHJlc2VudGFkb3MgbmVzdGEgbGljZW7Dp2EsIGUgcXVlIGVzc2UgbWF0ZXJpYWwgZGUgcHJvcHJpZWRhZGUgZGUgdGVyY2Vpcm9zIGVzdMOhIGNsYXJhbWVudGUgaWRlbnRpZmljYWRvIGUgcmVjb25oZWNpZG8gbm8gdGV4dG8gb3Ugbm8gY29udGXDumRvIGRhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyBvcmEgZGVwb3NpdGFkYS4KCkNBU08gQSBURVNFIE9VIERJU1NFUlRBw4fDg08gT1JBIERFUE9TSVRBREEgVEVOSEEgU0lETyBSRVNVTFRBRE8gREUgVU0gUEFUUk9Dw41OSU8gT1UgQVBPSU8gREUgVU1BIEFHw4pOQ0lBIERFIEZPTUVOVE8gT1UgT1VUUk8gT1JHQU5JU01PIFFVRSBOw4NPIFNFSkEgQSBVRk1BLCBWT0PDiiBERUNMQVJBIFFVRSBSRVNQRUlUT1UgVE9ET1MgRSBRVUFJU1FVRVIgRElSRUlUT1MgREUgUkVWSVPDg08gQ09NTyBUQU1Cw4lNIEFTIERFTUFJUyBPQlJJR0HDh8OVRVMgRVhJR0lEQVMgUE9SIENPTlRSQVRPIE9VIEFDT1JETy4KCkEgVUZNQSBzZSBjb21wcm9tZXRlIGEgaWRlbnRpZmljYXIgY2xhcmFtZW50ZSBvIHNldSBub21lIG91IG8ocykgbm9tZShzKSBkbyhzKSBkZXRlbnRvcihlcykgZG9zIGRpcmVpdG9zIGF1dG9yYWlzIGRhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbywgZSBuw6NvIGZhcsOhIHF1YWxxdWVyIGFsdGVyYcOnw6NvLCBhbMOpbSBkYXF1ZWxhcyBjb25jZWRpZGFzIHBvciBlc3RhIGxpY2Vuw6dhLgoKRGVjbGFyYSB0YW1iw6ltIHF1ZSB0b2RhcyBhcyBhZmlsaWHDp8O1ZXMgY29ycG9yYXRpdmFzIG91IGluc3RpdHVjaW9uYWlzIGUgdG9kYXMgYXMgZm9udGVzIGRlIGFwb2lvIGZpbmFuY2Vpcm8gYW8gdHJhYmFsaG8gZXN0w6NvIGRldmlkYW1lbnRlIGNpdGFkYXMgb3UgbWVuY2lvbmFkYXMgZSBjZXJ0aWZpY2EgcXVlIG7Do28gaMOhIG5lbmh1bSBpbnRlcmVzc2UgY29tZXJjaWFsIG91IGFzc29jaWF0aXZvIHF1ZSByZXByZXNlbnRlIGNvbmZsaXRvIGRlIGludGVyZXNzZSBlbSBjb25leMOjbyBjb20gbyB0cmFiYWxobyBzdWJtZXRpZG8uCgoKCgoKCgo=Biblioteca Digital de Teses e Dissertaçõeshttps://tedebc.ufma.br/jspui/PUBhttp://tedebc.ufma.br:8080/oai/requestrepositorio@ufma.br||repositorio@ufma.bropendoar:21312022-11-08T11:18:07Biblioteca Digital de Teses e Dissertações da UFMA - Universidade Federal do Maranhão (UFMA)false |
dc.title.por.fl_str_mv |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
dc.title.alternative.eng.fl_str_mv |
Application of a mobilization protocol, based on functional level, in patients submitted to cardiac surgery: controlled, randomized clinical trial |
title |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
spellingShingle |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado BORGES, Mayara Gabrielle Barbosa Procedimentos cirúrgicos cardiovasculares; Movimento; Força Muscular. Cardiovascular surgical procedures; Movement; Muscle strength. Cirurgia Cardiovascular Ciências da Saúde |
title_short |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
title_full |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
title_fullStr |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
title_full_unstemmed |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
title_sort |
Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado |
author |
BORGES, Mayara Gabrielle Barbosa |
author_facet |
BORGES, Mayara Gabrielle Barbosa |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
NINA, Vinicius José da Silva Nina |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/5148313598301706 |
dc.contributor.advisor-co1.fl_str_mv |
BORGES, Daniel Lago |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/0732282114720827 |
dc.contributor.referee1.fl_str_mv |
DIBAI, Daniela Bassi |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/0861598490954598 |
dc.contributor.referee2.fl_str_mv |
MONTEIRO, Silvio Gomes |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/1682966336184874 |
dc.contributor.referee3.fl_str_mv |
SIQUEIRA FILHO, Mário Alves de |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/4816046653397785 |
dc.contributor.referee4.fl_str_mv |
REGO, Adriana Sousa |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/7001225083239682 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/3992896109526229 |
dc.contributor.author.fl_str_mv |
BORGES, Mayara Gabrielle Barbosa |
contributor_str_mv |
NINA, Vinicius José da Silva Nina BORGES, Daniel Lago DIBAI, Daniela Bassi MONTEIRO, Silvio Gomes SIQUEIRA FILHO, Mário Alves de REGO, Adriana Sousa |
dc.subject.por.fl_str_mv |
Procedimentos cirúrgicos cardiovasculares; Movimento; Força Muscular. |
topic |
Procedimentos cirúrgicos cardiovasculares; Movimento; Força Muscular. Cardiovascular surgical procedures; Movement; Muscle strength. Cirurgia Cardiovascular Ciências da Saúde |
dc.subject.eng.fl_str_mv |
Cardiovascular surgical procedures; Movement; Muscle strength. |
dc.subject.cnpq.fl_str_mv |
Cirurgia Cardiovascular Ciências da Saúde |
description |
Patients undergoing cardiac surgery may present functional changes in the postoperative period. Several physiotherapeutic interventions have been described aiming to minimize the functional loss related to the surgical procedure. However, they present as a limitation the use of generalist protocols that are not based on the individuality of patients. Thus, this research proposes to verify the effects of the application of an adapted mobilization protocol, based on the functional level, on mobility, peripheral muscle strength, length of stay in the Intensive Care Unit (ICU) and hospital of patients undergoing cardiac surgery. We conducted a randomized controlled trial with adult patients (18 to 60 years old), of both sexes, who underwent cardiac surgery from January 2020 to June 2021. Patients were evaluated regarding: (i) time, in hours, to achieve mobilization milestones (bedside sitting, out of bed sitting, standing and walking); (ii) level of mobility, using the ICU Mobility Scale (IMS); (iii) peripheral muscle strength, using hand grip dynamometry; and (iv) length of stay in the ICU and hospital. Participants were randomized into two groups: a control group (conventional mobilization protocol) and an intervention group (functional level-based mobilization protocol). The intervention protocol was adapted from the study by Hodgson et al. (2016), based on the IMS level, and the conventional protocol, as recommended by Winkelmann et al. (2015). In chapter 1, we provide, through a systematic review, the description of exercise prescription in patients undergoing cardiac surgery. In conclusion, most protocols are generalist, progressive, low intensity, with frequency of twice a day and duration of 10 to 30 minutes. In chapter II, the impact of an individualized protocol on the mobility of patients undergoing cardiac surgery compared to the conventional protocol was evaluated. No statistically significant differences were found in the two types of protocol regarding mobilization milestones and mobility level, peripheral muscle strength, length of stay in the Intensive Care Unit (ICU) and hospital comparing the protocols. |
publishDate |
2022 |
dc.date.accessioned.fl_str_mv |
2022-11-07T17:24:20Z |
dc.date.issued.fl_str_mv |
2022-06-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BORGES, Mayara Gabrielle Barbosa. Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado. 2022. 89 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís. |
dc.identifier.uri.fl_str_mv |
https://tedebc.ufma.br/jspui/handle/tede/tede/4275 |
identifier_str_mv |
BORGES, Mayara Gabrielle Barbosa. Aplicação de um protocolo de mobilização, baseado no nivel funcional, em pacientes submetidos à cirurgia cardíaca: ensaio clínico, controlado e randomizado. 2022. 89 f. Tese (Programa de Pós-Graduação em Ciências da Saúde/CCBS) - Universidade Federal do Maranhão, São Luís. |
url |
https://tedebc.ufma.br/jspui/handle/tede/tede/4275 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
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dc.publisher.none.fl_str_mv |
Universidade Federal do Maranhão |
dc.publisher.program.fl_str_mv |
PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBS |
dc.publisher.initials.fl_str_mv |
UFMA |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
DEPARTAMENTO DE MEDICINA I/CCBS |
publisher.none.fl_str_mv |
Universidade Federal do Maranhão |
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