Adverse events following human papillomavirus vaccine in adolescents in the state of Minas Gerais

• Autor(a) principal: Luvisaro, Bianca Maria Oliveira
• Data de Publicação: 2022
• Outros Autores: Silva, Thales Philipe Rodrigues, Felisbino-Mendes, Mariana Santos, Silva, Tércia Moreira Ribeiro da, Silva, Roberta Barros da, Lachtim, Sheila Aparecida Ferreira, Freitas, Giselle Lima de, Matozinhos, Fernanda Penido
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Reme (Online)
• Texto Completo: https://periodicos.ufmg.br/index.php/reme/article/view/40892
• topic: Vacinação; Adolescente; Epidemiologia; Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos; Sistemas de informação; Vaccination; Adolescent; Epidemiology; Drug-Related Side Effects and Adverse Reactions; Information Systems; Vacunación; Adolescente; Epidemiología; Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos; Sistemas de Información

Objective: to investigate reports of adverse events following human papillomavirus vaccination in the state of Minas Gerais, according to the location of notification, causality, severity, and evolution of cases. Methods: epidemiological study carried out with data from 2015-2019, reported in the Adverse Event Surveillance Information System. Data were analyzed and presented in proportions, according to health macro-regions and years of study. Results: in 2015, 26.41% of adverse events were reported, being the year with the highest number of notifications. In the analysis of health macro-regions, Vale do Jequitinhonha had the lowest prevalence of registration (0.43%), and the Center had the highest prevalence of notification (30.95%). The most prevalent local adverse events were pain (56.48%) and edema (38.89%). As for systemic events, headache (29.69%) and gastroenteritis (29.69%) had the highest number of cases. Events classified as non-serious adverse events (59.82%) were the most prevalent, and regarding the cause, 35.94% of them were attributed to immunization errors. Conclusion: this study reinforces that adverse events following HPV vaccination were, for the most part, non-serious events, thus demonstrating the safety of the HPV vaccine for the adolescent public, contributing to the increase in vaccine coverage rates.