Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares

Detalhes bibliográficos
Autor(a) principal: Christovão,F.G.
Data de Publicação: 2006
Outros Autores: Zamur,G., Mataqueiro,M.I., Queiroz-Neto,A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000600009
Resumo: The sedative and antinociceptive effects of romifidine (0.1mg/kg) and of xylazine (1.0mg/kg) on Thoroughbred mares were studied. Sedation was evaluated by quantifying spontaneous locomotor activity (SLA) and head height (HH) in animals placed in automated individual behaviour stalls. Antinociception was determined utilizing a heat irradiation lamp recording the latency time for the hoof withdrawal reflex (HWRL) and the latency time for the skin twitch reflex (STRL) in a randomised block design with 10 replicates. Comparison of the sedative effects of romifidine and of xylazine on SLA showed a faster effect for xylazine. Regarding the sedative effect of the substances based on HH, romifidine caused a longer-lasting effect. Romifidine caused an increase in HWRL and STRL, and xylazine, an agent known for its analgesic effect, did not have an antinociceptive effect based on STRL result. The antinociceptive effect of romifidine was more pronounced than the xylazine effect.
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spelling Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mareshorseromifidinexylazineantinociceptionsedationThe sedative and antinociceptive effects of romifidine (0.1mg/kg) and of xylazine (1.0mg/kg) on Thoroughbred mares were studied. Sedation was evaluated by quantifying spontaneous locomotor activity (SLA) and head height (HH) in animals placed in automated individual behaviour stalls. Antinociception was determined utilizing a heat irradiation lamp recording the latency time for the hoof withdrawal reflex (HWRL) and the latency time for the skin twitch reflex (STRL) in a randomised block design with 10 replicates. Comparison of the sedative effects of romifidine and of xylazine on SLA showed a faster effect for xylazine. Regarding the sedative effect of the substances based on HH, romifidine caused a longer-lasting effect. Romifidine caused an increase in HWRL and STRL, and xylazine, an agent known for its analgesic effect, did not have an antinociceptive effect based on STRL result. The antinociceptive effect of romifidine was more pronounced than the xylazine effect.Universidade Federal de Minas Gerais, Escola de Veterinária2006-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000600009Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.6 2006reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352006000600009info:eu-repo/semantics/openAccessChristovão,F.G.Zamur,G.Mataqueiro,M.I.Queiroz-Neto,A.eng2007-03-14T00:00:00Zoai:scielo:S0102-09352006000600009Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2007-03-14T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
title Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
spellingShingle Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
Christovão,F.G.
horse
romifidine
xylazine
antinociception
sedation
title_short Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
title_full Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
title_fullStr Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
title_full_unstemmed Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
title_sort Sedative and antinociceptive effects of romifidine and xylazine in Thoroughbred mares
author Christovão,F.G.
author_facet Christovão,F.G.
Zamur,G.
Mataqueiro,M.I.
Queiroz-Neto,A.
author_role author
author2 Zamur,G.
Mataqueiro,M.I.
Queiroz-Neto,A.
author2_role author
author
author
dc.contributor.author.fl_str_mv Christovão,F.G.
Zamur,G.
Mataqueiro,M.I.
Queiroz-Neto,A.
dc.subject.por.fl_str_mv horse
romifidine
xylazine
antinociception
sedation
topic horse
romifidine
xylazine
antinociception
sedation
description The sedative and antinociceptive effects of romifidine (0.1mg/kg) and of xylazine (1.0mg/kg) on Thoroughbred mares were studied. Sedation was evaluated by quantifying spontaneous locomotor activity (SLA) and head height (HH) in animals placed in automated individual behaviour stalls. Antinociception was determined utilizing a heat irradiation lamp recording the latency time for the hoof withdrawal reflex (HWRL) and the latency time for the skin twitch reflex (STRL) in a randomised block design with 10 replicates. Comparison of the sedative effects of romifidine and of xylazine on SLA showed a faster effect for xylazine. Regarding the sedative effect of the substances based on HH, romifidine caused a longer-lasting effect. Romifidine caused an increase in HWRL and STRL, and xylazine, an agent known for its analgesic effect, did not have an antinociceptive effect based on STRL result. The antinociceptive effect of romifidine was more pronounced than the xylazine effect.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000600009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000600009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-09352006000600009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.6 2006
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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