Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático
Autor(a) principal: | |
---|---|
Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000400038 |
Resumo: | Alanine aminotransferase (ALT) and alkaline phosphatase (AP) hepatic enzymes, hematological values, and total plasmatic proteins (TPP) of 12 Wistar rats with systemic experimental sporotrichosis were evaluated. Inoculation was performed at 2x10³ cells of S. schenckii/ml. The values ranged from 35 to 48UI/l for ALT and 67 to 251.3UI/l for AP. Fifty percent of the AP values were above the physiological limits. TPP was elevated in 66.7% (8/12) of the rats with values varying from 7.9 to 8.5g%. In 75% (9/12) of the animals, it was observed that hemoglobin and red blood cells count were below the physiologic limits, and 8.3% (1/12) of the animals showed anemia masked by dehydration. At the necropsy, it was observed local and/or disseminated nodular lesions. At the histological analysis, cells compatible to S. schenckii were found. The observed alterations are aggravating factors for the recurrence and treatment of the mycosis. |
id |
UFMG-8_79161a0d889fca3fbb26a9dfe624272f |
---|---|
oai_identifier_str |
oai:scielo:S0102-09352008000400038 |
network_acronym_str |
UFMG-8 |
network_name_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository_id_str |
|
spelling |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepáticoratoesporotricose experimentalSporotrix schenckiienzimas hepáticasAlanine aminotransferase (ALT) and alkaline phosphatase (AP) hepatic enzymes, hematological values, and total plasmatic proteins (TPP) of 12 Wistar rats with systemic experimental sporotrichosis were evaluated. Inoculation was performed at 2x10³ cells of S. schenckii/ml. The values ranged from 35 to 48UI/l for ALT and 67 to 251.3UI/l for AP. Fifty percent of the AP values were above the physiological limits. TPP was elevated in 66.7% (8/12) of the rats with values varying from 7.9 to 8.5g%. In 75% (9/12) of the animals, it was observed that hemoglobin and red blood cells count were below the physiologic limits, and 8.3% (1/12) of the animals showed anemia masked by dehydration. At the necropsy, it was observed local and/or disseminated nodular lesions. At the histological analysis, cells compatible to S. schenckii were found. The observed alterations are aggravating factors for the recurrence and treatment of the mycosis.Universidade Federal de Minas Gerais, Escola de Veterinária2008-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000400038Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.60 n.4 2008reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352008000400038info:eu-repo/semantics/openAccessMeinerz,A.R.M.Antunes,T.A.Silva,F.V.Xavier,M.O.Cleff,M.B.Meireles,M.C.A.por2008-08-15T00:00:00Zoai:scielo:S0102-09352008000400038Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2008-08-15T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
title |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
spellingShingle |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático Meinerz,A.R.M. rato esporotricose experimental Sporotrix schenckii enzimas hepáticas |
title_short |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
title_full |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
title_fullStr |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
title_full_unstemmed |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
title_sort |
Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático |
author |
Meinerz,A.R.M. |
author_facet |
Meinerz,A.R.M. Antunes,T.A. Silva,F.V. Xavier,M.O. Cleff,M.B. Meireles,M.C.A. |
author_role |
author |
author2 |
Antunes,T.A. Silva,F.V. Xavier,M.O. Cleff,M.B. Meireles,M.C.A. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Meinerz,A.R.M. Antunes,T.A. Silva,F.V. Xavier,M.O. Cleff,M.B. Meireles,M.C.A. |
dc.subject.por.fl_str_mv |
rato esporotricose experimental Sporotrix schenckii enzimas hepáticas |
topic |
rato esporotricose experimental Sporotrix schenckii enzimas hepáticas |
description |
Alanine aminotransferase (ALT) and alkaline phosphatase (AP) hepatic enzymes, hematological values, and total plasmatic proteins (TPP) of 12 Wistar rats with systemic experimental sporotrichosis were evaluated. Inoculation was performed at 2x10³ cells of S. schenckii/ml. The values ranged from 35 to 48UI/l for ALT and 67 to 251.3UI/l for AP. Fifty percent of the AP values were above the physiological limits. TPP was elevated in 66.7% (8/12) of the rats with values varying from 7.9 to 8.5g%. In 75% (9/12) of the animals, it was observed that hemoglobin and red blood cells count were below the physiologic limits, and 8.3% (1/12) of the animals showed anemia masked by dehydration. At the necropsy, it was observed local and/or disseminated nodular lesions. At the histological analysis, cells compatible to S. schenckii were found. The observed alterations are aggravating factors for the recurrence and treatment of the mycosis. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000400038 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000400038 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
10.1590/S0102-09352008000400038 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
dc.source.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.60 n.4 2008 reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online) instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
collection |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository.name.fl_str_mv |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br |
_version_ |
1750220881845551104 |