Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report

Detalhes bibliográficos
Autor(a) principal: Nunes,M.M.
Data de Publicação: 2021
Outros Autores: Garcia,A.P.V., Nakagaki,K.Y.R., Cassali,G.D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351
Resumo: ABSTRACT The malignant adenomyoepithelioma is a rare mammary tumor in women and uncommon in cats with only one report in this species. In this case report, the histopathological and immunohistochemical characteristics of six cases of malignant adenomyopithelioma in the feline mammary gland are described. Microscopic evaluation of tumors showed dense cellular neoplastic proliferation, composed of malignant myoepithelial and epithelial cells, formed by varied arrangements and presenting papillary, tubular and solid nest proliferation. Immunohistochemistry was performed for markers Ki67, Cox-2, RE, RP, p63 and HER-2. All cases were positive for p63, confirming the myoepithelial nature of neoplastic cells. The diagnosis of malignant adenomyopithelioma was made possible through the association between histopathological characteristics and immunohistochemical results.
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spelling Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case reportcatmalignant adenomyoepitheliomadiagnosisABSTRACT The malignant adenomyoepithelioma is a rare mammary tumor in women and uncommon in cats with only one report in this species. In this case report, the histopathological and immunohistochemical characteristics of six cases of malignant adenomyopithelioma in the feline mammary gland are described. Microscopic evaluation of tumors showed dense cellular neoplastic proliferation, composed of malignant myoepithelial and epithelial cells, formed by varied arrangements and presenting papillary, tubular and solid nest proliferation. Immunohistochemistry was performed for markers Ki67, Cox-2, RE, RP, p63 and HER-2. All cases were positive for p63, confirming the myoepithelial nature of neoplastic cells. The diagnosis of malignant adenomyopithelioma was made possible through the association between histopathological characteristics and immunohistochemical results.Universidade Federal de Minas Gerais, Escola de Veterinária2021-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.73 n.6 2021reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/1678-4162-12312info:eu-repo/semantics/openAccessNunes,M.M.Garcia,A.P.V.Nakagaki,K.Y.R.Cassali,G.D.eng2021-12-16T00:00:00Zoai:scielo:S0102-09352021000701351Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2021-12-16T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
title Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
spellingShingle Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
Nunes,M.M.
cat
malignant adenomyoepithelioma
diagnosis
title_short Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
title_full Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
title_fullStr Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
title_full_unstemmed Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
title_sort Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
author Nunes,M.M.
author_facet Nunes,M.M.
Garcia,A.P.V.
Nakagaki,K.Y.R.
Cassali,G.D.
author_role author
author2 Garcia,A.P.V.
Nakagaki,K.Y.R.
Cassali,G.D.
author2_role author
author
author
dc.contributor.author.fl_str_mv Nunes,M.M.
Garcia,A.P.V.
Nakagaki,K.Y.R.
Cassali,G.D.
dc.subject.por.fl_str_mv cat
malignant adenomyoepithelioma
diagnosis
topic cat
malignant adenomyoepithelioma
diagnosis
description ABSTRACT The malignant adenomyoepithelioma is a rare mammary tumor in women and uncommon in cats with only one report in this species. In this case report, the histopathological and immunohistochemical characteristics of six cases of malignant adenomyopithelioma in the feline mammary gland are described. Microscopic evaluation of tumors showed dense cellular neoplastic proliferation, composed of malignant myoepithelial and epithelial cells, formed by varied arrangements and presenting papillary, tubular and solid nest proliferation. Immunohistochemistry was performed for markers Ki67, Cox-2, RE, RP, p63 and HER-2. All cases were positive for p63, confirming the myoepithelial nature of neoplastic cells. The diagnosis of malignant adenomyopithelioma was made possible through the association between histopathological characteristics and immunohistochemical results.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4162-12312
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.73 n.6 2021
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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