Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes

Detalhes bibliográficos
Autor(a) principal: Cadioli,F.A.
Data de Publicação: 2006
Outros Autores: Marques,L.C., Machado,R.Z., Alessi,A.C., Aquino,L.P.C.T., Barnabé,P A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500008
Resumo: Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease. The course of the experimental infection was followed up to 145 days. Hematological analyses of the infected donkeys revealed a marked decline in hemoglobin, packed-cell volume, and erythrocyte count. Anemia was observed after successive peaks of parasitemia. Biochemical analyses showed increased levels of icterus index, serum globulins and decreased serum albumin and glucose values. All infected donkeys revealed enlargement of spleen and its white pulp, enlargement of mediastinal lymph nodes and lungs congestion. The main histopathological features consisted of meningoencephalitis. Demyelination in some areas of the cerebellum pediculus and neuropil vacuolization were observed. This study showed that donkeys infected with a Brazilian strain of T. evansi developed a chronic disease.
id UFMG-8_b46d113be4edeaa52cda0353386f27ce
oai_identifier_str oai:scielo:S0102-09352006000500008
network_acronym_str UFMG-8
network_name_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository_id_str
spelling Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changesdonkeyexperimental infectionTrypanosoma evansitrypanosomiasisFive adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease. The course of the experimental infection was followed up to 145 days. Hematological analyses of the infected donkeys revealed a marked decline in hemoglobin, packed-cell volume, and erythrocyte count. Anemia was observed after successive peaks of parasitemia. Biochemical analyses showed increased levels of icterus index, serum globulins and decreased serum albumin and glucose values. All infected donkeys revealed enlargement of spleen and its white pulp, enlargement of mediastinal lymph nodes and lungs congestion. The main histopathological features consisted of meningoencephalitis. Demyelination in some areas of the cerebellum pediculus and neuropil vacuolization were observed. This study showed that donkeys infected with a Brazilian strain of T. evansi developed a chronic disease.Universidade Federal de Minas Gerais, Escola de Veterinária2006-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500008Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.5 2006reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352006000500008info:eu-repo/semantics/openAccessCadioli,F.A.Marques,L.C.Machado,R.Z.Alessi,A.C.Aquino,L.P.C.T.Barnabé,P A.eng2007-01-15T00:00:00Zoai:scielo:S0102-09352006000500008Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2007-01-15T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
title Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
spellingShingle Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
Cadioli,F.A.
donkey
experimental infection
Trypanosoma evansi
trypanosomiasis
title_short Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
title_full Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
title_fullStr Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
title_full_unstemmed Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
title_sort Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
author Cadioli,F.A.
author_facet Cadioli,F.A.
Marques,L.C.
Machado,R.Z.
Alessi,A.C.
Aquino,L.P.C.T.
Barnabé,P A.
author_role author
author2 Marques,L.C.
Machado,R.Z.
Alessi,A.C.
Aquino,L.P.C.T.
Barnabé,P A.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cadioli,F.A.
Marques,L.C.
Machado,R.Z.
Alessi,A.C.
Aquino,L.P.C.T.
Barnabé,P A.
dc.subject.por.fl_str_mv donkey
experimental infection
Trypanosoma evansi
trypanosomiasis
topic donkey
experimental infection
Trypanosoma evansi
trypanosomiasis
description Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease. The course of the experimental infection was followed up to 145 days. Hematological analyses of the infected donkeys revealed a marked decline in hemoglobin, packed-cell volume, and erythrocyte count. Anemia was observed after successive peaks of parasitemia. Biochemical analyses showed increased levels of icterus index, serum globulins and decreased serum albumin and glucose values. All infected donkeys revealed enlargement of spleen and its white pulp, enlargement of mediastinal lymph nodes and lungs congestion. The main histopathological features consisted of meningoencephalitis. Demyelination in some areas of the cerebellum pediculus and neuropil vacuolization were observed. This study showed that donkeys infected with a Brazilian strain of T. evansi developed a chronic disease.
publishDate 2006
dc.date.none.fl_str_mv 2006-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-09352006000500008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.5 2006
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
_version_ 1750220879671853056

Registros relacionados