Quantitative computed tomography of the liver in dogs submitted to prednisone therapy
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000400020 |
Resumo: | The aim of this study is to evaluate the possible alterations in radiodensity of the hepatic parenchyma and spleen resulting from the corticotherapy with prednisone, correlating these findings with serum biochemical hepatic transaminase activity. A clinical trial was performed on eight healthy dogs with the intent of evaluating possible hepatic alterations after prednisone therapy using quantitative computed tomography. All animals received prednisone orally at a dose of 2mg/kg of weight for 30 days. The radiodensity of the liver and spleen was determined before and after the period that the medication was administered. An increase in the radiodensity of the hepatic parenchyma between the initial and final experimental stages was observed. In the present study the existence of early hepatic alterations were verified, which are compatible with glycogen storage. |
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Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
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Quantitative computed tomography of the liver in dogs submitted to prednisone therapydogcomputed tomographyglycogenosisradiodensityglucocorticoidThe aim of this study is to evaluate the possible alterations in radiodensity of the hepatic parenchyma and spleen resulting from the corticotherapy with prednisone, correlating these findings with serum biochemical hepatic transaminase activity. A clinical trial was performed on eight healthy dogs with the intent of evaluating possible hepatic alterations after prednisone therapy using quantitative computed tomography. All animals received prednisone orally at a dose of 2mg/kg of weight for 30 days. The radiodensity of the liver and spleen was determined before and after the period that the medication was administered. An increase in the radiodensity of the hepatic parenchyma between the initial and final experimental stages was observed. In the present study the existence of early hepatic alterations were verified, which are compatible with glycogen storage.Universidade Federal de Minas Gerais, Escola de Veterinária2013-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000400020Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.65 n.4 2013reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352013000400020info:eu-repo/semantics/openAccessCosta,L.A.V.S.Oliveira,D.C.Lopes,B.F.Lanis,A.B.Teixeira,M.W.Costa,F.S.eng2013-09-03T00:00:00Zoai:scielo:S0102-09352013000400020Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2013-09-03T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
title |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
spellingShingle |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy Costa,L.A.V.S. dog computed tomography glycogenosis radiodensity glucocorticoid |
title_short |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
title_full |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
title_fullStr |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
title_full_unstemmed |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
title_sort |
Quantitative computed tomography of the liver in dogs submitted to prednisone therapy |
author |
Costa,L.A.V.S. |
author_facet |
Costa,L.A.V.S. Oliveira,D.C. Lopes,B.F. Lanis,A.B. Teixeira,M.W. Costa,F.S. |
author_role |
author |
author2 |
Oliveira,D.C. Lopes,B.F. Lanis,A.B. Teixeira,M.W. Costa,F.S. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Costa,L.A.V.S. Oliveira,D.C. Lopes,B.F. Lanis,A.B. Teixeira,M.W. Costa,F.S. |
dc.subject.por.fl_str_mv |
dog computed tomography glycogenosis radiodensity glucocorticoid |
topic |
dog computed tomography glycogenosis radiodensity glucocorticoid |
description |
The aim of this study is to evaluate the possible alterations in radiodensity of the hepatic parenchyma and spleen resulting from the corticotherapy with prednisone, correlating these findings with serum biochemical hepatic transaminase activity. A clinical trial was performed on eight healthy dogs with the intent of evaluating possible hepatic alterations after prednisone therapy using quantitative computed tomography. All animals received prednisone orally at a dose of 2mg/kg of weight for 30 days. The radiodensity of the liver and spleen was determined before and after the period that the medication was administered. An increase in the radiodensity of the hepatic parenchyma between the initial and final experimental stages was observed. In the present study the existence of early hepatic alterations were verified, which are compatible with glycogen storage. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000400020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000400020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-09352013000400020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
dc.source.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.65 n.4 2013 reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online) instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
collection |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository.name.fl_str_mv |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br |
_version_ |
1750220886753935360 |