Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation

Detalhes bibliográficos
Autor(a) principal: Nunes,N.
Data de Publicação: 2003
Outros Autores: Martins,S.E.C., Santos,P.S.P., Rezende,M.L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000200008
Resumo: The aim of this study was to compare the effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation. General anesthesia was induced in 30 healthy, adult, mongrel dogs by intravenous administration of propofol. The animals were separated into three groups of 10 dogs each and submitted to general inhalation anesthesia with 1.5 MAC of desflurane (G1), sevoflurane (G2) and isoflurane (G3). Arterial blood was collected by puncture of the right femoral artery, and mixed blood was collected by introducing a Swan-Ganz catheter into the pulmonary artery. These samples were used to determine the parameters employed for calculation of the intrapulmonary shunt. Measurements began at 20min after orotracheal intubation and were repeated every 20min, totaling six measurements. Means were compared by the Student t-test (P<FONT FACE=Symbol>£</FONT> 0.05). Desflurane led to a higher shunt than sevoflurane and isoflurane at 40 and 60min. At 80min, the mean values obtained for desflurane were higher than those obtained for isoflurane, while at 100min the values observed for dogs anesthetized with desflurane were higher than those obtained with sevoflurane. Desflurane caused respiratory depression by reducing PaO2, and a higher percentage of intrapulmonary shunt than isoflurane and sevoflurane.
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spelling Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilationdogintrapulmonary shuntdesfluraneisofluranesevofluraneThe aim of this study was to compare the effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation. General anesthesia was induced in 30 healthy, adult, mongrel dogs by intravenous administration of propofol. The animals were separated into three groups of 10 dogs each and submitted to general inhalation anesthesia with 1.5 MAC of desflurane (G1), sevoflurane (G2) and isoflurane (G3). Arterial blood was collected by puncture of the right femoral artery, and mixed blood was collected by introducing a Swan-Ganz catheter into the pulmonary artery. These samples were used to determine the parameters employed for calculation of the intrapulmonary shunt. Measurements began at 20min after orotracheal intubation and were repeated every 20min, totaling six measurements. Means were compared by the Student t-test (P<FONT FACE=Symbol>£</FONT> 0.05). Desflurane led to a higher shunt than sevoflurane and isoflurane at 40 and 60min. At 80min, the mean values obtained for desflurane were higher than those obtained for isoflurane, while at 100min the values observed for dogs anesthetized with desflurane were higher than those obtained with sevoflurane. Desflurane caused respiratory depression by reducing PaO2, and a higher percentage of intrapulmonary shunt than isoflurane and sevoflurane.Universidade Federal de Minas Gerais, Escola de Veterinária2003-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000200008Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.55 n.2 2003reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352003000200008info:eu-repo/semantics/openAccessNunes,N.Martins,S.E.C.Santos,P.S.P.Rezende,M.L.eng2003-07-15T00:00:00Zoai:scielo:S0102-09352003000200008Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2003-07-15T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
title Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
spellingShingle Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
Nunes,N.
dog
intrapulmonary shunt
desflurane
isoflurane
sevoflurane
title_short Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
title_full Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
title_fullStr Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
title_full_unstemmed Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
title_sort Effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation
author Nunes,N.
author_facet Nunes,N.
Martins,S.E.C.
Santos,P.S.P.
Rezende,M.L.
author_role author
author2 Martins,S.E.C.
Santos,P.S.P.
Rezende,M.L.
author2_role author
author
author
dc.contributor.author.fl_str_mv Nunes,N.
Martins,S.E.C.
Santos,P.S.P.
Rezende,M.L.
dc.subject.por.fl_str_mv dog
intrapulmonary shunt
desflurane
isoflurane
sevoflurane
topic dog
intrapulmonary shunt
desflurane
isoflurane
sevoflurane
description The aim of this study was to compare the effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation. General anesthesia was induced in 30 healthy, adult, mongrel dogs by intravenous administration of propofol. The animals were separated into three groups of 10 dogs each and submitted to general inhalation anesthesia with 1.5 MAC of desflurane (G1), sevoflurane (G2) and isoflurane (G3). Arterial blood was collected by puncture of the right femoral artery, and mixed blood was collected by introducing a Swan-Ganz catheter into the pulmonary artery. These samples were used to determine the parameters employed for calculation of the intrapulmonary shunt. Measurements began at 20min after orotracheal intubation and were repeated every 20min, totaling six measurements. Means were compared by the Student t-test (P<FONT FACE=Symbol>£</FONT> 0.05). Desflurane led to a higher shunt than sevoflurane and isoflurane at 40 and 60min. At 80min, the mean values obtained for desflurane were higher than those obtained for isoflurane, while at 100min the values observed for dogs anesthetized with desflurane were higher than those obtained with sevoflurane. Desflurane caused respiratory depression by reducing PaO2, and a higher percentage of intrapulmonary shunt than isoflurane and sevoflurane.
publishDate 2003
dc.date.none.fl_str_mv 2003-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-09352003000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.55 n.2 2003
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
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