West Nile Virus in Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFMG |
| Texto Completo: | https://doi.org/10.3390/pathogens10070896 http://hdl.handle.net/1843/67584 https://orcid.org/0000-0001-5521-6448 https://orcid.org/0000-0003-3916-2018 https://orcid.org/0000-0002-5849-7326 https://orcid.org/0000-0002-2257-7076 https://orcid.org/0000-0002-1067-1882 https://orcid.org/0000-0002-3629-8529 https://orcid.org/0000-0002-6734-0216 https://orcid.org/0000-0002-1497-4397 https://orcid.org/0000-0003-3731-3660 |
Resumo: | Outra Agência |
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2024-04-23T14:39:50Z2024-04-23T14:39:50Z2021-07-1510789614https://doi.org/10.3390/pathogens100708962076-0817http://hdl.handle.net/1843/67584https://orcid.org/0000-0001-5521-6448https://orcid.org/0000-0003-3916-2018https://orcid.org/0000-0002-5849-7326https://orcid.org/0000-0002-2257-7076https://orcid.org/0000-0002-1067-1882https://orcid.org/0000-0002-3629-8529https://orcid.org/0000-0002-6734-0216https://orcid.org/0000-0002-1497-4397https://orcid.org/0000-0003-3731-3660Outra AgênciaBackground: West Nile virus (WNV) was first sequenced in Brazil in 2019, when it was isolated from a horse in the Espírito Santo state. Despite multiple studies reporting serological evidence suggestive of past circulation since 2004, WNV remains a low priority for surveillance and public health, such that much is still unknown about its genomic diversity, evolution, and transmission in the country. Methods: A combination of diagnostic assays, nanopore sequencing, phylogenetic inference, and epidemiological modeling are here used to provide a holistic overview of what is known about WNV in Brazil. Results: We report new genetic evidence of WNV circulation in southern (Minas Gerais, São Paulo) and northeastern (Piauí) states isolated from equine red blood cells. A novel, climate-informed theoretical perspective of the potential transmission of WNV across the country highlights the state of Piauí as particularly relevant for WNV epidemiology in Brazil, although it does not reject possible circulation in other states. Conclusion: Our output demonstrates the scarceness of existing data, and that although there is sufficient evidence for the circulation and persistence of the virus, much is still unknown on its local evolution, epidemiology, and activity. We advocate for a shift to active surveillance, to ensure adequate preparedness for future epidemics with spill-over potential to humans.engUniversidade Federal de Minas GeraisUFMGBrasilVET - DEPARTAMENTO DE CLÍNICA E CIRURGIAVET - DEPARTAMENTO DE MEDICINA VETERINÁRIA PREVENTIVAVETER - ESCOLA DE VETERINARIAPathogensVírus do Nilo OcidentalGenomaMoléculasBrasilWest Nile virusGenomic monitoringMolecular detectionBrazilWest Nile Virus in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.mdpi.com/2076-0817/10/7/896Érica Azevedo CostaDanielle Freitas HenriquesDaniele Barbosa de Almeida MedeirosMaria Isabel Maldonado Coelho GuedesBeatriz Senra Álvares da Silva SantosAila Solimar Gonçalves SilvaRenata de Pino Albuquerque MaranhãoNieli Rodrigues da Costa FariaRenata Farinelli de SiqueiraTulio de OliveiraKarina Ribeiro Leite Jardim CavalcanteMarta GiovanettiNoely Fabiana Oliveira de MouraAlessandro Pecego Martins RomanoCarlos F. Campelo de AlbuquerqueLauro César Soares FeitosaJosé Joffre Martins BayeuxRaffaella Bertoni Cavalcanti TeixeiraOsmaikon Lisboa LobatoSilvokleio da Costa SilvaAna Maria Bispo de FilippisRivaldo Venâncio da CunhaLilian Silva CatenacciJosé LourençoLuiz Carlos Junior AlcantaraVagner FonsecaFlávia Figueira AburjaileFlávia l. l. ChalhoubJoilson XavierFelipe Campos de Melo IaniMarcelo Adriano da Cunha e Silva Vieiraapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/67584/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALWest Nile Virus in Brazil.pdfWest Nile Virus in Brazil.pdfapplication/pdf722618https://repositorio.ufmg.br/bitstream/1843/67584/2/West%20Nile%20Virus%20in%20Brazil.pdf175bb87f5644de29383a9e232fbf2d96MD521843/675842024-04-23 11:39:51.343oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2024-04-23T14:39:51Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.pt_BR.fl_str_mv |
West Nile Virus in Brazil |
| title |
West Nile Virus in Brazil |
| spellingShingle |
West Nile Virus in Brazil Érica Azevedo Costa West Nile virus Genomic monitoring Molecular detection Brazil Vírus do Nilo Ocidental Genoma Moléculas Brasil |
| title_short |
West Nile Virus in Brazil |
| title_full |
West Nile Virus in Brazil |
| title_fullStr |
West Nile Virus in Brazil |
| title_full_unstemmed |
West Nile Virus in Brazil |
| title_sort |
West Nile Virus in Brazil |
| author |
Érica Azevedo Costa |
| author_facet |
Érica Azevedo Costa Danielle Freitas Henriques Daniele Barbosa de Almeida Medeiros Maria Isabel Maldonado Coelho Guedes Beatriz Senra Álvares da Silva Santos Aila Solimar Gonçalves Silva Renata de Pino Albuquerque Maranhão Nieli Rodrigues da Costa Faria Renata Farinelli de Siqueira Tulio de Oliveira Karina Ribeiro Leite Jardim Cavalcante Marta Giovanetti Noely Fabiana Oliveira de Moura Alessandro Pecego Martins Romano Carlos F. Campelo de Albuquerque Lauro César Soares Feitosa José Joffre Martins Bayeux Raffaella Bertoni Cavalcanti Teixeira Osmaikon Lisboa Lobato Silvokleio da Costa Silva Ana Maria Bispo de Filippis Rivaldo Venâncio da Cunha Lilian Silva Catenacci José Lourenço Luiz Carlos Junior Alcantara Vagner Fonseca Flávia Figueira Aburjaile Flávia l. l. Chalhoub Joilson Xavier Felipe Campos de Melo Iani Marcelo Adriano da Cunha e Silva Vieira |
| author_role |
author |
| author2 |
Danielle Freitas Henriques Daniele Barbosa de Almeida Medeiros Maria Isabel Maldonado Coelho Guedes Beatriz Senra Álvares da Silva Santos Aila Solimar Gonçalves Silva Renata de Pino Albuquerque Maranhão Nieli Rodrigues da Costa Faria Renata Farinelli de Siqueira Tulio de Oliveira Karina Ribeiro Leite Jardim Cavalcante Marta Giovanetti Noely Fabiana Oliveira de Moura Alessandro Pecego Martins Romano Carlos F. Campelo de Albuquerque Lauro César Soares Feitosa José Joffre Martins Bayeux Raffaella Bertoni Cavalcanti Teixeira Osmaikon Lisboa Lobato Silvokleio da Costa Silva Ana Maria Bispo de Filippis Rivaldo Venâncio da Cunha Lilian Silva Catenacci José Lourenço Luiz Carlos Junior Alcantara Vagner Fonseca Flávia Figueira Aburjaile Flávia l. l. Chalhoub Joilson Xavier Felipe Campos de Melo Iani Marcelo Adriano da Cunha e Silva Vieira |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Érica Azevedo Costa Danielle Freitas Henriques Daniele Barbosa de Almeida Medeiros Maria Isabel Maldonado Coelho Guedes Beatriz Senra Álvares da Silva Santos Aila Solimar Gonçalves Silva Renata de Pino Albuquerque Maranhão Nieli Rodrigues da Costa Faria Renata Farinelli de Siqueira Tulio de Oliveira Karina Ribeiro Leite Jardim Cavalcante Marta Giovanetti Noely Fabiana Oliveira de Moura Alessandro Pecego Martins Romano Carlos F. Campelo de Albuquerque Lauro César Soares Feitosa José Joffre Martins Bayeux Raffaella Bertoni Cavalcanti Teixeira Osmaikon Lisboa Lobato Silvokleio da Costa Silva Ana Maria Bispo de Filippis Rivaldo Venâncio da Cunha Lilian Silva Catenacci José Lourenço Luiz Carlos Junior Alcantara Vagner Fonseca Flávia Figueira Aburjaile Flávia l. l. Chalhoub Joilson Xavier Felipe Campos de Melo Iani Marcelo Adriano da Cunha e Silva Vieira |
| dc.subject.por.fl_str_mv |
West Nile virus Genomic monitoring Molecular detection Brazil |
| topic |
West Nile virus Genomic monitoring Molecular detection Brazil Vírus do Nilo Ocidental Genoma Moléculas Brasil |
| dc.subject.other.pt_BR.fl_str_mv |
Vírus do Nilo Ocidental Genoma Moléculas Brasil |
| description |
Outra Agência |
| publishDate |
2021 |
| dc.date.issued.fl_str_mv |
2021-07-15 |
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2024-04-23T14:39:50Z |
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2024-04-23T14:39:50Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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http://hdl.handle.net/1843/67584 |
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https://doi.org/10.3390/pathogens10070896 |
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2076-0817 |
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https://orcid.org/0000-0001-5521-6448 https://orcid.org/0000-0003-3916-2018 https://orcid.org/0000-0002-5849-7326 https://orcid.org/0000-0002-2257-7076 https://orcid.org/0000-0002-1067-1882 https://orcid.org/0000-0002-3629-8529 https://orcid.org/0000-0002-6734-0216 https://orcid.org/0000-0002-1497-4397 https://orcid.org/0000-0003-3731-3660 |
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2076-0817 |
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eng |
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Pathogens |
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Universidade Federal de Minas Gerais |
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Brasil |
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Universidade Federal de Minas Gerais |
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