Extra-abdominal desmoid tumor: local recurrence and treatment options

Detalhes bibliográficos
Autor(a) principal: Luiz Eduardo Moreira Teixeira
Data de Publicação: 2016
Outros Autores: Eugênio Costa Arantes, Rafael Freitas Villela, Claudio Beling Gonçalves Soares, Roberto Bitarães de Carvalho Costa, Marco Antônio Percope de Andrade
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/41459
Resumo: Objective: To evaluate the rate of local recurrence of extra-abdominal desmoid tumor and compare the outcomes of surgical treatment and conservative treatment. Methods: Twenty one patients (14 women and seven men), mean age 33.0±8.7 years old, with a diagnosis of desmoid tumor were evaluated. The mean follow-up period was 58.5±29.0 months. Fourteen cases involved the lower limbs, four cases involved the upper limbs, and three cases involved the trunk. The average tumor size was 12.7±7.5 cm. Of the 21 patients, 14 did not undergo previous treatment and seven patients relapsed before the initial evaluation. Surgical treatment was performed in 16 patients and conservative treatment was performed in five patients. Results: Recurrence occurred in seven patients (33%) and six of them relapsed within the first 18 months. No significant difference was observed between conservative and surgical treatment. However, a significant difference was observed among patients undergoing wide resection and who experienced improved local control. Conclusion: The recurrence rate of desmoid tumor was 33.3%. There was no difference in recurrence between conservative and surgical treatment. In surgical treatment, wide margins showed better results for recurrence control. Level of Evidence III. Retrospective Observational Study.
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spelling 2022-05-06T23:26:21Z2022-05-06T23:26:21Z201624314715010.1590/1413-7852201624031421821809-4406http://hdl.handle.net/1843/41459Objective: To evaluate the rate of local recurrence of extra-abdominal desmoid tumor and compare the outcomes of surgical treatment and conservative treatment. Methods: Twenty one patients (14 women and seven men), mean age 33.0±8.7 years old, with a diagnosis of desmoid tumor were evaluated. The mean follow-up period was 58.5±29.0 months. Fourteen cases involved the lower limbs, four cases involved the upper limbs, and three cases involved the trunk. The average tumor size was 12.7±7.5 cm. Of the 21 patients, 14 did not undergo previous treatment and seven patients relapsed before the initial evaluation. Surgical treatment was performed in 16 patients and conservative treatment was performed in five patients. Results: Recurrence occurred in seven patients (33%) and six of them relapsed within the first 18 months. No significant difference was observed between conservative and surgical treatment. However, a significant difference was observed among patients undergoing wide resection and who experienced improved local control. Conclusion: The recurrence rate of desmoid tumor was 33.3%. There was no difference in recurrence between conservative and surgical treatment. In surgical treatment, wide margins showed better results for recurrence control. Level of Evidence III. Retrospective Observational Study.Objetivo: Avaliar a taxa de recorrência local do tumor desmoide extra-abdominal e comparar os resultados do tratamento cirúrgico e do tratamento conservador. Métodos: Foram avaliados 21 pacientes (14 mulheres e sete homens), com idade média de 33,0±8,7 anos, com diagnóstico de tumor desmoide. O período médio de seguimento foi de 58,5±29,0 meses. Quatorze casos envolveram os membros inferiores, quatro casos envolveram os membros superiores e três casos envolveram o tronco. O tamanho médio do tumor foi de 12,7±7,5 cm. Dos 21 pacientes, 14 não realizaram tratamento prévio e sete pacientes recidivaram antes da avaliação inicial. O tratamento cirúrgico foi realizado em 16 pacientes e o tratamento conservador foi realizado em cinco pacientes. Resultados: A recorrência ocorreu em sete pacientes (33%) e seis deles recidivaram nos primeiros 18 meses. Não foi observada diferença significativa entre o tratamento conservador e cirúrgico. No entanto, uma diferença significativa foi observada entre os pacientes submetidos à ressecção ampla e que apresentaram melhora do controle local. Conclusão: A taxa de recorrência do tumor desmoide foi de 33,3%. Não houve diferença na recorrência entre o tratamento conservador e cirúrgico. No tratamento cirúrgico, margens amplas mostraram melhores resultados para controle de recidiva. Nível de evidência III. Estudo Observacional Retrospectivo.engUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE APARELHO LOCOMOTORActa ortopédica brasileiraFibromatose agressivaOncologia médicaRecorrênciaExtra-abdominal desmoid tumor: local recurrence and treatment optionsTumor desmoide extra-abdominal: recorrência local e opções de tratamentoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/aob/a/n47WTF5NgJCST9fdS3kW6bn/?lang=enLuiz Eduardo Moreira TeixeiraEugênio Costa ArantesRafael Freitas VillelaClaudio Beling Gonçalves SoaresRoberto Bitarães de Carvalho CostaMarco Antônio Percope de Andradeapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/41459/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINAL2016_Extra-abdominal desmoid tumor- local recurrence and treatment options.pdf2016_Extra-abdominal desmoid tumor- local recurrence and treatment options.pdfapplication/pdf191374https://repositorio.ufmg.br/bitstream/1843/41459/2/2016_Extra-abdominal%20desmoid%20tumor-%20local%20recurrence%20and%20treatment%20options.pdf4544a02b2371ce1edf997a573bea5633MD521843/414592022-05-06 20:26:21.788oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2022-05-06T23:26:21Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Extra-abdominal desmoid tumor: local recurrence and treatment options
dc.title.alternative.pt_BR.fl_str_mv Tumor desmoide extra-abdominal: recorrência local e opções de tratamento
title Extra-abdominal desmoid tumor: local recurrence and treatment options
spellingShingle Extra-abdominal desmoid tumor: local recurrence and treatment options
Luiz Eduardo Moreira Teixeira
Fibromatose agressiva
Oncologia médica
Recorrência
title_short Extra-abdominal desmoid tumor: local recurrence and treatment options
title_full Extra-abdominal desmoid tumor: local recurrence and treatment options
title_fullStr Extra-abdominal desmoid tumor: local recurrence and treatment options
title_full_unstemmed Extra-abdominal desmoid tumor: local recurrence and treatment options
title_sort Extra-abdominal desmoid tumor: local recurrence and treatment options
author Luiz Eduardo Moreira Teixeira
author_facet Luiz Eduardo Moreira Teixeira
Eugênio Costa Arantes
Rafael Freitas Villela
Claudio Beling Gonçalves Soares
Roberto Bitarães de Carvalho Costa
Marco Antônio Percope de Andrade
author_role author
author2 Eugênio Costa Arantes
Rafael Freitas Villela
Claudio Beling Gonçalves Soares
Roberto Bitarães de Carvalho Costa
Marco Antônio Percope de Andrade
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Luiz Eduardo Moreira Teixeira
Eugênio Costa Arantes
Rafael Freitas Villela
Claudio Beling Gonçalves Soares
Roberto Bitarães de Carvalho Costa
Marco Antônio Percope de Andrade
dc.subject.other.pt_BR.fl_str_mv Fibromatose agressiva
Oncologia médica
Recorrência
topic Fibromatose agressiva
Oncologia médica
Recorrência
description Objective: To evaluate the rate of local recurrence of extra-abdominal desmoid tumor and compare the outcomes of surgical treatment and conservative treatment. Methods: Twenty one patients (14 women and seven men), mean age 33.0±8.7 years old, with a diagnosis of desmoid tumor were evaluated. The mean follow-up period was 58.5±29.0 months. Fourteen cases involved the lower limbs, four cases involved the upper limbs, and three cases involved the trunk. The average tumor size was 12.7±7.5 cm. Of the 21 patients, 14 did not undergo previous treatment and seven patients relapsed before the initial evaluation. Surgical treatment was performed in 16 patients and conservative treatment was performed in five patients. Results: Recurrence occurred in seven patients (33%) and six of them relapsed within the first 18 months. No significant difference was observed between conservative and surgical treatment. However, a significant difference was observed among patients undergoing wide resection and who experienced improved local control. Conclusion: The recurrence rate of desmoid tumor was 33.3%. There was no difference in recurrence between conservative and surgical treatment. In surgical treatment, wide margins showed better results for recurrence control. Level of Evidence III. Retrospective Observational Study.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2022-05-06T23:26:21Z
dc.date.available.fl_str_mv 2022-05-06T23:26:21Z
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dc.identifier.doi.pt_BR.fl_str_mv 10.1590/1413-785220162403142182
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dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv MED - DEPARTAMENTO DE APARELHO LOCOMOTOR
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
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