Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFMG |
| Texto Completo: | https://doi.org/10.1590/1678-7757-2022-0227 http://hdl.handle.net/1843/68230 http://orcid.org/0000-0002-4697-5503 http://orcid.org/0000-0003-3246-3301 http://orcid.org/0000-0003-0675-9053 http://orcid.org/0000-0002-0886-4407 http://orcid.org/0000-0003-4261-0037 http://orcid.org/0000-0001-9947-0261 http://orcid.org/0000-0002-2050-0729 http://orcid.org/0000-0002-5759-612X http://orcid.org/0000-0003-1383-6299 http://orcid.org/0000-0001-5605-6976 http://orcid.org/0000-0001-7643-6589 |
Resumo: | CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico |
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2024-05-13T14:54:21Z2024-05-13T14:54:21Z202230https://doi.org/10.1590/1678-7757-2022-02271678-7765http://hdl.handle.net/1843/68230http://orcid.org/0000-0002-4697-5503http://orcid.org/0000-0003-3246-3301http://orcid.org/0000-0003-0675-9053http://orcid.org/0000-0002-0886-4407http://orcid.org/0000-0003-4261-0037http://orcid.org/0000-0001-9947-0261http://orcid.org/0000-0002-2050-0729http://orcid.org/0000-0002-5759-612Xhttp://orcid.org/0000-0003-1383-6299http://orcid.org/0000-0001-5605-6976http://orcid.org/0000-0001-7643-6589CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorTo evaluate the release of bisphenol-A glycidyl methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA), bisphenol A (BPA), and phthalates of the composite resin used in the bonding of spurs applied in the treatment of children with anterior open bite and its effects on human keratinocytes. Methodology: Saliva samples of 22 children were collected before spur attachment (baseline) and 30 minutes (min) and 24 hours (h) after spur bonding. Analysis was performed using high-performance liquid chromatography (HPLC) coupled to tandem mass spectrometry (HPLC–MS/ MS) and gas chromatography coupled to mass spectrometry (GC–MS). Standardized resin increments were added to three different dilutions of the cell culture medium. Keratinocytes (HaCaT) were cultivated in the conditioned media and evaluated for cell viability (MTT) and cell scratch assay. Results: The levels of BisGMA (1.74±0.27 μg/mL), TEGDMA (2.29±0.36 μg/mL), and BPA (3.264±0.88 μg/L) in the saliva after 30 min, in comparison to baseline (0±0 μg/mL, 0±0 μg/mL, and 1.15±0.21 μg/L, respectively), presented higher numbers. After 24 h, the levels of the monomers were similar to the baseline. Phthalates showed no significant difference among groups. HaCat cells showed increased viability and reduced cell migration over time after exposure to methacrylate-based resin composites. Conclusion: Resin composites, used to attach spurs in children with anterior open bite during orthodontic treatment, release monomers after polymerization and can influence the behavior of human keratinocytes, even at very low concentrations. Orthodontists should be aware of the risks of the resinous compounds release and preventive procedures should be held to reduce patient exposure.engUniversidade Federal de Minas GeraisUFMGBrasilFAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORAICX - DEPARTAMENTO DE QUÍMICAJournal of Applied Oral ScienceCompostos orgânicosResinas dentáriasCromatografia liquida de alta eficienciaEspectrometria de massaCromatografia a gásMethacrylatesBisphenol-A glycidyl methacrylateDibutyl phthalateKeratinocytesOpen biteRelease of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spurinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/jaos/a/sT8WBdmtYJBNt46DpwgXhSKGabriel Antônio dos Anjos TouJosé Messias GomesLuíza Santana de Oliveira RincoMonica YamautiIvana Márcia Alves DinizFabiane PiresMarcella Emilia Petra SchmidtHelvécio Costa MenezesZenilda de Lourdes CardealCarla Beatriz Grespan BottoliSoraia Macariapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/68230/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALRelease of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur (1).pdfRelease of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur (1).pdfapplication/pdf833126https://repositorio.ufmg.br/bitstream/1843/68230/2/Release%20of%20leachable%20products%20from%20resinous%20compounds%20in%20the%20saliva%20of%20children%20with%20anterior%20open%20bite%20treated%20with%20spur%20%281%29.pdfb7cbf5f6b8c1a64485ec15c88f146a83MD521843/682302024-05-13 11:54:21.77oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2024-05-13T14:54:21Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.pt_BR.fl_str_mv |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| title |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| spellingShingle |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur Gabriel Antônio dos Anjos Tou Methacrylates Bisphenol-A glycidyl methacrylate Dibutyl phthalate Keratinocytes Open bite Compostos orgânicos Resinas dentárias Cromatografia liquida de alta eficiencia Espectrometria de massa Cromatografia a gás |
| title_short |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| title_full |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| title_fullStr |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| title_full_unstemmed |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| title_sort |
Release of leachable products from resinous compounds in the saliva of children with anterior open bite treated with spur |
| author |
Gabriel Antônio dos Anjos Tou |
| author_facet |
Gabriel Antônio dos Anjos Tou José Messias Gomes Luíza Santana de Oliveira Rinco Monica Yamauti Ivana Márcia Alves Diniz Fabiane Pires Marcella Emilia Petra Schmidt Helvécio Costa Menezes Zenilda de Lourdes Cardeal Carla Beatriz Grespan Bottoli Soraia Macari |
| author_role |
author |
| author2 |
José Messias Gomes Luíza Santana de Oliveira Rinco Monica Yamauti Ivana Márcia Alves Diniz Fabiane Pires Marcella Emilia Petra Schmidt Helvécio Costa Menezes Zenilda de Lourdes Cardeal Carla Beatriz Grespan Bottoli Soraia Macari |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Gabriel Antônio dos Anjos Tou José Messias Gomes Luíza Santana de Oliveira Rinco Monica Yamauti Ivana Márcia Alves Diniz Fabiane Pires Marcella Emilia Petra Schmidt Helvécio Costa Menezes Zenilda de Lourdes Cardeal Carla Beatriz Grespan Bottoli Soraia Macari |
| dc.subject.por.fl_str_mv |
Methacrylates Bisphenol-A glycidyl methacrylate Dibutyl phthalate Keratinocytes Open bite |
| topic |
Methacrylates Bisphenol-A glycidyl methacrylate Dibutyl phthalate Keratinocytes Open bite Compostos orgânicos Resinas dentárias Cromatografia liquida de alta eficiencia Espectrometria de massa Cromatografia a gás |
| dc.subject.other.pt_BR.fl_str_mv |
Compostos orgânicos Resinas dentárias Cromatografia liquida de alta eficiencia Espectrometria de massa Cromatografia a gás |
| description |
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico |
| publishDate |
2022 |
| dc.date.issued.fl_str_mv |
2022 |
| dc.date.accessioned.fl_str_mv |
2024-05-13T14:54:21Z |
| dc.date.available.fl_str_mv |
2024-05-13T14:54:21Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/1843/68230 |
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https://doi.org/10.1590/1678-7757-2022-0227 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1678-7765 |
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http://orcid.org/0000-0002-4697-5503 http://orcid.org/0000-0003-3246-3301 http://orcid.org/0000-0003-0675-9053 http://orcid.org/0000-0002-0886-4407 http://orcid.org/0000-0003-4261-0037 http://orcid.org/0000-0001-9947-0261 http://orcid.org/0000-0002-2050-0729 http://orcid.org/0000-0002-5759-612X http://orcid.org/0000-0003-1383-6299 http://orcid.org/0000-0001-5605-6976 http://orcid.org/0000-0001-7643-6589 |
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https://doi.org/10.1590/1678-7757-2022-0227 http://hdl.handle.net/1843/68230 http://orcid.org/0000-0002-4697-5503 http://orcid.org/0000-0003-3246-3301 http://orcid.org/0000-0003-0675-9053 http://orcid.org/0000-0002-0886-4407 http://orcid.org/0000-0003-4261-0037 http://orcid.org/0000-0001-9947-0261 http://orcid.org/0000-0002-2050-0729 http://orcid.org/0000-0002-5759-612X http://orcid.org/0000-0003-1383-6299 http://orcid.org/0000-0001-5605-6976 http://orcid.org/0000-0001-7643-6589 |
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1678-7765 |
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eng |
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eng |
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Journal of Applied Oral Science |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Universidade Federal de Minas Gerais |
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UFMG |
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Brasil |
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FAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA ICX - DEPARTAMENTO DE QUÍMICA |
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Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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