Avaliação da qualidade de vida de pacientes com doença falciforme

Detalhes bibliográficos
Autor(a) principal: Sílvia Letícia de Oliveira Toledo
Data de Publicação: 2020
Outros Autores: Gustavo Cambraia Trindade, Cynthia Teixeira Pimenta, Aline de Freitas Lopes, Patrícia Nessralla Alpoim, Danyelle Romana Alves Rios, Melina de Barros Pinheiro
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://dx.doi.org/10.5935/2238-3182.20200013
http://hdl.handle.net/1843/51091
Resumo: Introduction: sickle cell disease (SCD) comprises a group of hereditary hemolytic anemias whose main characteristic is the presence of the hemoglobin S (Hb S) gene that can be combined with other hereditary blood abnormalities. The clinical picture ranges from almost asymptomatic to severe forms. Hydroxyurea (HU) is the most successful therapy. It is a chronic disease whose prevalence and morbidity are high in Brazil, thus quality of life (QoL) emerges as an important challenge for patients, family members and health professionals. Objectives: This study aimed to evaluate the QoL of patients with SCD, their sociodemographic and clinical characteristics. Methods: Data were collected through the abbreviated QoL questionnaire (WHOQOL-Bref), sociodemographic questionnaire and clinical chart. Results: It has interviewed at the Hemominas Foundation in Divinópolis - MG, 39 patients aged 18-54. Most of the patients were male (56%), homozygous for Hb S (80%), unmarried (67%), completed high school (31%) and non HU users (61%). Among the patients evaluated, 53.8% considered having a good QoL (mean score 74.2 ± 20.3). The overall QoL score was 71.5. The physical and environmental domains had the lowest mean scores (61.5 and 59.0, respectively). No significant differences were found among those using or not using HU. Conclusions: Patients with SCD presented good QoL, being more affected by aspects related to the environmental domain (such as financial resources) and physical (such as pain and discomfort) those correlate with clinical and social characteristics related to SCD.
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spelling Avaliação da qualidade de vida de pacientes com doença falciformeEvaluation of the quality of life of patients with sickle cell diseaseQualidade de vidaHemoglobina falciformeAnemiaInquéritos e questionáriosHematologiaHemoglobina falciformeAnemiaQualidade de vidaIntroduction: sickle cell disease (SCD) comprises a group of hereditary hemolytic anemias whose main characteristic is the presence of the hemoglobin S (Hb S) gene that can be combined with other hereditary blood abnormalities. The clinical picture ranges from almost asymptomatic to severe forms. Hydroxyurea (HU) is the most successful therapy. It is a chronic disease whose prevalence and morbidity are high in Brazil, thus quality of life (QoL) emerges as an important challenge for patients, family members and health professionals. Objectives: This study aimed to evaluate the QoL of patients with SCD, their sociodemographic and clinical characteristics. Methods: Data were collected through the abbreviated QoL questionnaire (WHOQOL-Bref), sociodemographic questionnaire and clinical chart. Results: It has interviewed at the Hemominas Foundation in Divinópolis - MG, 39 patients aged 18-54. Most of the patients were male (56%), homozygous for Hb S (80%), unmarried (67%), completed high school (31%) and non HU users (61%). Among the patients evaluated, 53.8% considered having a good QoL (mean score 74.2 ± 20.3). The overall QoL score was 71.5. The physical and environmental domains had the lowest mean scores (61.5 and 59.0, respectively). No significant differences were found among those using or not using HU. Conclusions: Patients with SCD presented good QoL, being more affected by aspects related to the environmental domain (such as financial resources) and physical (such as pain and discomfort) those correlate with clinical and social characteristics related to SCD.Introdução: A doença falciforme (DF) compreende um grupo de anemias hemolíticas hereditárias cuja principal característica é a presença do gene da hemoglobina S (Hb S) que pode combinar-se com outras anormalidades sanguíneas hereditárias. O quadro clínico varia desde quase assintomático até formas graves. A Hidroxiuréia (HU) é a terapia de maior sucesso. É uma doença crônica, cuja prevalência e morbidade são altas no Brasil, dessa forma a qualidade de vida (QV) surge como um importante desafio para os pacientes, familiares e profissionais de saúde. Objetivos: Avaliar a QV de pacientes portadores de DF, suas características sociodemográficas e clínicas. Métodos: Os dados foram coletados através do questionário de QV abreviado (WHOQOL-Bref), questionário sociodemográfico e prontuário clínico. Resultados: foram entrevistados 39 pacientes, entre 18 e 54 anos, tratados na Fundação Hemominas em Divinópolis - MG. A maioria dos pacientes eram homens (56%), homozigotos para a Hb S (80%), solteiros (67%), segundo grau completo (31%) e não usuários de HU (61%). Dentre os pacientes avaliados 53,8% considerou ter boa QV (escore médio 74,2 ±20,3). O escore relacionado à QV geral foi de 71,5. Os domínios físico e meio ambiente obtiveram os menores escores médio (61,5 e 59,0, respectivamente). Não foram encontradas diferenças significativas entre os que utilizavam ou não HU. Conclusões: Os pacientes com DF apresentaram boa QV, sendo mais comprometida pelos aspectos relacionados ao domínio meio ambiente, (como recursos financeiros) e físico (como dor e desconforto) que se correlacionam com as características clínicas e sociais relacionadas a DF.CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoUniversidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASUFMG2023-03-21T15:28:24Z2023-03-21T15:28:24Z2020info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdfhttp://dx.doi.org/10.5935/2238-3182.202000132238-3182http://hdl.handle.net/1843/51091porRevista Médica de Minas GeraisSílvia Letícia de Oliveira ToledoGustavo Cambraia TrindadeCynthia Teixeira PimentaAline de Freitas LopesPatrícia Nessralla AlpoimDanyelle Romana Alves RiosMelina de Barros Pinheiroinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2023-03-21T17:45:21Zoai:repositorio.ufmg.br:1843/51091Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2023-03-21T17:45:21Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Avaliação da qualidade de vida de pacientes com doença falciforme
Evaluation of the quality of life of patients with sickle cell disease
title Avaliação da qualidade de vida de pacientes com doença falciforme
spellingShingle Avaliação da qualidade de vida de pacientes com doença falciforme
Sílvia Letícia de Oliveira Toledo
Qualidade de vida
Hemoglobina falciforme
Anemia
Inquéritos e questionários
Hematologia
Hemoglobina falciforme
Anemia
Qualidade de vida
title_short Avaliação da qualidade de vida de pacientes com doença falciforme
title_full Avaliação da qualidade de vida de pacientes com doença falciforme
title_fullStr Avaliação da qualidade de vida de pacientes com doença falciforme
title_full_unstemmed Avaliação da qualidade de vida de pacientes com doença falciforme
title_sort Avaliação da qualidade de vida de pacientes com doença falciforme
author Sílvia Letícia de Oliveira Toledo
author_facet Sílvia Letícia de Oliveira Toledo
Gustavo Cambraia Trindade
Cynthia Teixeira Pimenta
Aline de Freitas Lopes
Patrícia Nessralla Alpoim
Danyelle Romana Alves Rios
Melina de Barros Pinheiro
author_role author
author2 Gustavo Cambraia Trindade
Cynthia Teixeira Pimenta
Aline de Freitas Lopes
Patrícia Nessralla Alpoim
Danyelle Romana Alves Rios
Melina de Barros Pinheiro
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sílvia Letícia de Oliveira Toledo
Gustavo Cambraia Trindade
Cynthia Teixeira Pimenta
Aline de Freitas Lopes
Patrícia Nessralla Alpoim
Danyelle Romana Alves Rios
Melina de Barros Pinheiro
dc.subject.por.fl_str_mv Qualidade de vida
Hemoglobina falciforme
Anemia
Inquéritos e questionários
Hematologia
Hemoglobina falciforme
Anemia
Qualidade de vida
topic Qualidade de vida
Hemoglobina falciforme
Anemia
Inquéritos e questionários
Hematologia
Hemoglobina falciforme
Anemia
Qualidade de vida
description Introduction: sickle cell disease (SCD) comprises a group of hereditary hemolytic anemias whose main characteristic is the presence of the hemoglobin S (Hb S) gene that can be combined with other hereditary blood abnormalities. The clinical picture ranges from almost asymptomatic to severe forms. Hydroxyurea (HU) is the most successful therapy. It is a chronic disease whose prevalence and morbidity are high in Brazil, thus quality of life (QoL) emerges as an important challenge for patients, family members and health professionals. Objectives: This study aimed to evaluate the QoL of patients with SCD, their sociodemographic and clinical characteristics. Methods: Data were collected through the abbreviated QoL questionnaire (WHOQOL-Bref), sociodemographic questionnaire and clinical chart. Results: It has interviewed at the Hemominas Foundation in Divinópolis - MG, 39 patients aged 18-54. Most of the patients were male (56%), homozygous for Hb S (80%), unmarried (67%), completed high school (31%) and non HU users (61%). Among the patients evaluated, 53.8% considered having a good QoL (mean score 74.2 ± 20.3). The overall QoL score was 71.5. The physical and environmental domains had the lowest mean scores (61.5 and 59.0, respectively). No significant differences were found among those using or not using HU. Conclusions: Patients with SCD presented good QoL, being more affected by aspects related to the environmental domain (such as financial resources) and physical (such as pain and discomfort) those correlate with clinical and social characteristics related to SCD.
publishDate 2020
dc.date.none.fl_str_mv 2020
2023-03-21T15:28:24Z
2023-03-21T15:28:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.5935/2238-3182.20200013
2238-3182
http://hdl.handle.net/1843/51091
url http://dx.doi.org/10.5935/2238-3182.20200013
http://hdl.handle.net/1843/51091
identifier_str_mv 2238-3182
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Médica de Minas Gerais
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv pdf
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dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
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