Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado

Detalhes bibliográficos
Autor(a) principal: Leonardo Maciel da Fonseca
Data de Publicação: 2010
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/BUOS-8GRP9L
Resumo: The benefits of early feeding after abdominal operations have been known since 1979. It is known that the introduction of the diet, both enterally and orally, before the end of postoperative ileus, in patients undergoing gastrointestinal surgery promotes better metabolic recovery and reduces hospital stay. To maximize postoperative recovery specific protocols known as fast track have been described. The main goals of such protocols are the attenuation of the organic response to surgical stress, thus leading to accelerated recovery, decreased complications and, hospital stay. Despite substantial evidence on this kind of benefits, mainly on colorectal surgery, slow changes in surgical practice have been described. Among the reasons raised, the difficulty in implementing complex protocols have been pointed out. The aim of this prospective randomized study was to evaluate the safety and benefits of a simplified program of postoperative rehabilitation after elective colectomy, mainly focused on early oral feeding. The hypothesis was that this current protocol could reduce the length of hospital stay without increasing complication and readmission rates, and with good tolerance to early oral diet. Fifty-eight patients admitted for elective colonic surgery were prospectively randomized into two groups: An early feeding group (EFG) on the first postoperative day (POD), patients initially received an oral liquid diet and were advanced to a regular diet within the next 24 hours as tolerated and at their discretion; a traditional care group (TCG) patients were managed by nothing per orus until the elimination of the first flatus and then received an oral liquid diet, followed by a regular diet within the next 24 hours as described for the EFG. All patients followed a well-defined, simplified rehabilitation program. Patients baseline characteristics were similar in the two groups except for the duration of surgery. Hospital stay was significantly lower in the EFG (median of 3 days (3-21) versus 4 days (3-33); p=0.000). Diet tolerance and progression were similar between groups. Time to first flatus after surgery was significantly lower in the EFG (2 days (1-2) versus 2 days (1-4); p=0.019). Complication and readmission rates were similar in both groups. Early oral nutrition associated with a simplified, well-defined perioperative rehabilitation program reduces postoperative ileus time and length of hospital stay after elective colonic resection without increasing rates of complications or readmissions.
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spelling Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizadohospitalizaçãoResultado de tratamentoCirurgia colorretalcomplicações pós-operatóriasMorbidadeCuidados pós-operatóriosAssistência perioperatóriaCirurgiaOftalmologiaThe benefits of early feeding after abdominal operations have been known since 1979. It is known that the introduction of the diet, both enterally and orally, before the end of postoperative ileus, in patients undergoing gastrointestinal surgery promotes better metabolic recovery and reduces hospital stay. To maximize postoperative recovery specific protocols known as fast track have been described. The main goals of such protocols are the attenuation of the organic response to surgical stress, thus leading to accelerated recovery, decreased complications and, hospital stay. Despite substantial evidence on this kind of benefits, mainly on colorectal surgery, slow changes in surgical practice have been described. Among the reasons raised, the difficulty in implementing complex protocols have been pointed out. The aim of this prospective randomized study was to evaluate the safety and benefits of a simplified program of postoperative rehabilitation after elective colectomy, mainly focused on early oral feeding. The hypothesis was that this current protocol could reduce the length of hospital stay without increasing complication and readmission rates, and with good tolerance to early oral diet. Fifty-eight patients admitted for elective colonic surgery were prospectively randomized into two groups: An early feeding group (EFG) on the first postoperative day (POD), patients initially received an oral liquid diet and were advanced to a regular diet within the next 24 hours as tolerated and at their discretion; a traditional care group (TCG) patients were managed by nothing per orus until the elimination of the first flatus and then received an oral liquid diet, followed by a regular diet within the next 24 hours as described for the EFG. All patients followed a well-defined, simplified rehabilitation program. Patients baseline characteristics were similar in the two groups except for the duration of surgery. Hospital stay was significantly lower in the EFG (median of 3 days (3-21) versus 4 days (3-33); p=0.000). Diet tolerance and progression were similar between groups. Time to first flatus after surgery was significantly lower in the EFG (2 days (1-2) versus 2 days (1-4); p=0.019). Complication and readmission rates were similar in both groups. Early oral nutrition associated with a simplified, well-defined perioperative rehabilitation program reduces postoperative ileus time and length of hospital stay after elective colonic resection without increasing rates of complications or readmissions.Os benefícios da alimentação precoce após operações abdominais são conhecidos desde 1979. Sabe-se que a introdução da dieta, tanto por via enteral, quanto por via oral (VO), antes do término do íleo pós-operatório (IPO) em pacientes submetidos a operações gastrointestinais favorece melhor recuperação metabólica e reduz o tempo de internação hospitalar. Para maximizar a recuperação pós-operatória, foi descrito protocolo específico conhecido como fast track. Esse protocolo objetiva a atenuação da resposta orgânica ao estresse cirúrgico, proporcionando recuperação pós-operatória mais rápida, diminuindo complicações e permanência hospitalar. Apesar de evidências substanciais desses benefícios com o emprego desse protocolo, principalmente nas ressecções colorretais, são observadas lentas mudanças na prática cirúrgica. Entre as razões levantadas, incluem-se as dificuldades para implementar protocolos complexos. O objetivo deste estudo prospectivo randomizado foi avaliar a segurança e os benefícios de programa de recuperação pós-operatória simplificado após colectomias eletivas, com ênfase na alimentação precoce por VO. A hipótese era de que esse protocolo simplificado pudesse reduzir o período de permanência hospitalar sem aumentar taxas de complicações e de readmissão e com boa tolerância à dieta precoce por VO. O total de 58 pacientes, submetidos a colectomias eletivas, foram prospectivamente alocados de forma aleatória em dois grupos. No grupo dieta precoce (GDP), os pacientes receberam dieta líquida por VO no primeiro DPO para observação da tolerância. Confirmada a tolerância, foi liberada dieta livre ainda no primeiro DPO; no grupo de cuidados tradicionais (GCT), os pacientes foram mantidos em jejum até a eliminação dos primeiros flatos, quando foi oferecida dieta por VO, inicialmente líquida e, posteriormente, livre, do mesmo modo que o GDP. Todos os pacientes seguiram programa simplificado de reabilitação pós-operatória. As características dos pacientes avaliados e de dados do pré, intra e pós-operatório foram similares em ambos os grupos, exceto pelo tempo operatório. A permanência hospitalar foi significativamente mais curta no GDP (mediana de três dias, 3-21, versus quatro dias, 3-33, p=0,000). A tolerância à dieta por VO e a progressão para dieta livre foram semelhantes entre os grupos. O tempo para eliminação dos primeiros flatos foi significativamente menor no GDP (dois dias,1-2, versus dois dias,1-4, p=0,019). Complicações e taxas de readmissão foram semelhantes em ambos os grupos. Concluiu-se que a alimentação precoce por VO associada ao programa de reabilitação pós-operatória simplificado descrito neste estudo reduziu o tempo de permanência hospitalar e do IPO em pacientes submetidos a ressecções eletivas do cólon, sem aumentar as taxas de complicações e readmissões e com boa tolerância à dieta por VO.Universidade Federal de Minas GeraisUFMGRodrigo Gomes da SilvaMaria Isabel Toulson Davisson CorreiaLeonardo Maciel da Fonseca2019-08-10T13:18:21Z2019-08-10T13:18:21Z2010-07-14info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/1843/BUOS-8GRP9Linfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2019-11-14T11:07:36Zoai:repositorio.ufmg.br:1843/BUOS-8GRP9LRepositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2019-11-14T11:07:36Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
title Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
spellingShingle Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
Leonardo Maciel da Fonseca
hospitalização
Resultado de tratamento
Cirurgia colorretal
complicações pós-operatórias
Morbidade
Cuidados pós-operatórios
Assistência perioperatória
Cirurgia
Oftalmologia
title_short Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
title_full Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
title_fullStr Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
title_full_unstemmed Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
title_sort Protocolo simplificado de recuperação pós-operatória em pacientes submetidos a colectomias eletivas: estudo prospectivo randomizado
author Leonardo Maciel da Fonseca
author_facet Leonardo Maciel da Fonseca
author_role author
dc.contributor.none.fl_str_mv Rodrigo Gomes da Silva
Maria Isabel Toulson Davisson Correia
dc.contributor.author.fl_str_mv Leonardo Maciel da Fonseca
dc.subject.por.fl_str_mv hospitalização
Resultado de tratamento
Cirurgia colorretal
complicações pós-operatórias
Morbidade
Cuidados pós-operatórios
Assistência perioperatória
Cirurgia
Oftalmologia
topic hospitalização
Resultado de tratamento
Cirurgia colorretal
complicações pós-operatórias
Morbidade
Cuidados pós-operatórios
Assistência perioperatória
Cirurgia
Oftalmologia
description The benefits of early feeding after abdominal operations have been known since 1979. It is known that the introduction of the diet, both enterally and orally, before the end of postoperative ileus, in patients undergoing gastrointestinal surgery promotes better metabolic recovery and reduces hospital stay. To maximize postoperative recovery specific protocols known as fast track have been described. The main goals of such protocols are the attenuation of the organic response to surgical stress, thus leading to accelerated recovery, decreased complications and, hospital stay. Despite substantial evidence on this kind of benefits, mainly on colorectal surgery, slow changes in surgical practice have been described. Among the reasons raised, the difficulty in implementing complex protocols have been pointed out. The aim of this prospective randomized study was to evaluate the safety and benefits of a simplified program of postoperative rehabilitation after elective colectomy, mainly focused on early oral feeding. The hypothesis was that this current protocol could reduce the length of hospital stay without increasing complication and readmission rates, and with good tolerance to early oral diet. Fifty-eight patients admitted for elective colonic surgery were prospectively randomized into two groups: An early feeding group (EFG) on the first postoperative day (POD), patients initially received an oral liquid diet and were advanced to a regular diet within the next 24 hours as tolerated and at their discretion; a traditional care group (TCG) patients were managed by nothing per orus until the elimination of the first flatus and then received an oral liquid diet, followed by a regular diet within the next 24 hours as described for the EFG. All patients followed a well-defined, simplified rehabilitation program. Patients baseline characteristics were similar in the two groups except for the duration of surgery. Hospital stay was significantly lower in the EFG (median of 3 days (3-21) versus 4 days (3-33); p=0.000). Diet tolerance and progression were similar between groups. Time to first flatus after surgery was significantly lower in the EFG (2 days (1-2) versus 2 days (1-4); p=0.019). Complication and readmission rates were similar in both groups. Early oral nutrition associated with a simplified, well-defined perioperative rehabilitation program reduces postoperative ileus time and length of hospital stay after elective colonic resection without increasing rates of complications or readmissions.
publishDate 2010
dc.date.none.fl_str_mv 2010-07-14
2019-08-10T13:18:21Z
2019-08-10T13:18:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/BUOS-8GRP9L
url http://hdl.handle.net/1843/BUOS-8GRP9L
dc.language.iso.fl_str_mv por
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
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institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
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