Covid-19 in brazilian children and adolescents: findings from 21 hospitals

Detalhes bibliográficos
Autor(a) principal: Priscila Menezes Ferriliu
Data de Publicação: 2021
Outros Autores: Guilherme Fagundes Nascimento, Helena Duani, Jamille Hemétrio Salles Martins Costa, Karen Brasil Ruschel, Matheus Carvalho Alves Nogueira, Neimy Ramos de Oliveira, Roberta Pozza, Saionara Cristina Francisco, Thalita Martins Lage, Yuri Carlotto Ramires, Maria do Carmo Barros de Melo, Daniella Nunes Pereira, Zilma Silveira Nogueira Reis, José Miguel Chatkin, Milena Soriano Marcolino, Lilian Martins Oliveira Diniz, Cristiane Dos Santos Dias, André Soares de Moura Costa, Bárbara Lopes Farace, Carla Thais Candida Alves da Silva, Fernando Anschau, Fernando Graça Aranha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/54883
https://orcid.org/0000-0001-9755-0364
Resumo: Introduction:Children and adolescents with Covid-19 have been shown lower mortality less intense symptoms when compared to adults, but studies in Brazil have been based on the compulsory notifying system only. Objective: To analyse clinical, laboratory, radiological characteristics and outcomes of hospitalized patients under 20 years with Covid-19. Methods: Cases series of hospitalized patients with confirmed Covid-19 under 20 years, obtained from a cohort study in 21 hospitals from five states of Brazil.Results: From 36 patients, 20 (55.5%) were adolescentes, 20 (55.5%) were male, 18 (50.0%) had comorbidities, 2 were pregnant and in 7 (19.4%), initial symptoms occurred during hospitalization for other causes, of whom 3 were possibly infected in the hospital. Fever (61.1%), dyspnea (33.3%) and neurological symptoms (33.0%) were the most common complaints. C-reactive protein was higher than 50mg/L in 16.7% and D-dimer was above the reference limit in 22.2%. Chest X-rays were performed in 20 (55.5%) patients, 9 had abnormalities, and chest tomography in 5. Hospital length of stay ranged from 1-40 days (median 5 [interquartile range 3-10]), 16 (44.4%) needed intensive therapy, 6 (16.7%) required mechanical ventilation and one patient (2.8%) died. Conclusion: In case series patients under 20 years from hospitals from 5 states of Brazil, comorbidities were frequent, and most common symptoms were fever, dyspnea and neurological symptoms. Forty-four percent required intensive therapy, showing that the disease was not as mild as it was expected, and one patient died.
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spelling 2023-06-13T20:13:48Z2023-06-13T20:13:48Z2021-08-097910.34117/bjdv7n9-01125258761http://hdl.handle.net/1843/54883https://orcid.org/0000-0001-9755-0364Introduction:Children and adolescents with Covid-19 have been shown lower mortality less intense symptoms when compared to adults, but studies in Brazil have been based on the compulsory notifying system only. Objective: To analyse clinical, laboratory, radiological characteristics and outcomes of hospitalized patients under 20 years with Covid-19. Methods: Cases series of hospitalized patients with confirmed Covid-19 under 20 years, obtained from a cohort study in 21 hospitals from five states of Brazil.Results: From 36 patients, 20 (55.5%) were adolescentes, 20 (55.5%) were male, 18 (50.0%) had comorbidities, 2 were pregnant and in 7 (19.4%), initial symptoms occurred during hospitalization for other causes, of whom 3 were possibly infected in the hospital. Fever (61.1%), dyspnea (33.3%) and neurological symptoms (33.0%) were the most common complaints. C-reactive protein was higher than 50mg/L in 16.7% and D-dimer was above the reference limit in 22.2%. Chest X-rays were performed in 20 (55.5%) patients, 9 had abnormalities, and chest tomography in 5. Hospital length of stay ranged from 1-40 days (median 5 [interquartile range 3-10]), 16 (44.4%) needed intensive therapy, 6 (16.7%) required mechanical ventilation and one patient (2.8%) died. Conclusion: In case series patients under 20 years from hospitals from 5 states of Brazil, comorbidities were frequent, and most common symptoms were fever, dyspnea and neurological symptoms. Forty-four percent required intensive therapy, showing that the disease was not as mild as it was expected, and one patient died.engUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE CLÍNICA MÉDICAMED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIAMED - DEPARTAMENTO DE PEDIATRIABrazilian Journal of DevelopmentPandemiasCovid-19CriançasAdolescentesPandemicCovid-19ChildrenAdolescentCovid-19 in brazilian children and adolescents: findings from 21 hospitalsCovid-19 em crianças e adolescentes brasileiros: registros de 21 hospitaisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/35338Priscila Menezes FerriliuGuilherme Fagundes NascimentoHelena DuaniJamille Hemétrio Salles Martins CostaKaren Brasil RuschelMatheus Carvalho Alves NogueiraNeimy Ramos de OliveiraRoberta PozzaSaionara Cristina FranciscoThalita Martins LageYuri Carlotto RamiresMaria do Carmo Barros de MeloDaniella Nunes PereiraZilma Silveira Nogueira ReisJosé Miguel ChatkinMilena Soriano MarcolinoLilian Martins Oliveira DinizCristiane Dos Santos DiasAndré Soares de Moura CostaBárbara Lopes FaraceCarla Thais Candida Alves da SilvaFernando AnschauFernando Graça Aranhaapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/54883/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALCOVID-19 in Brazilian children and adolescents findings from 21 hospitals.pdfCOVID-19 in Brazilian children and adolescents findings from 21 hospitals.pdfapplication/pdf774233https://repositorio.ufmg.br/bitstream/1843/54883/2/COVID-19%20in%20Brazilian%20children%20and%20adolescents%20findings%20from%2021%20hospitals.pdffe64a65267ea1b4354c792c2603b0e67MD521843/548832023-06-13 18:17:07.815oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-06-13T21:17:07Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Covid-19 in brazilian children and adolescents: findings from 21 hospitals
dc.title.alternative.pt_BR.fl_str_mv Covid-19 em crianças e adolescentes brasileiros: registros de 21 hospitais
title Covid-19 in brazilian children and adolescents: findings from 21 hospitals
spellingShingle Covid-19 in brazilian children and adolescents: findings from 21 hospitals
Priscila Menezes Ferriliu
Pandemic
Covid-19
Children
Adolescent
Pandemias
Covid-19
Crianças
Adolescentes
title_short Covid-19 in brazilian children and adolescents: findings from 21 hospitals
title_full Covid-19 in brazilian children and adolescents: findings from 21 hospitals
title_fullStr Covid-19 in brazilian children and adolescents: findings from 21 hospitals
title_full_unstemmed Covid-19 in brazilian children and adolescents: findings from 21 hospitals
title_sort Covid-19 in brazilian children and adolescents: findings from 21 hospitals
author Priscila Menezes Ferriliu
author_facet Priscila Menezes Ferriliu
Guilherme Fagundes Nascimento
Helena Duani
Jamille Hemétrio Salles Martins Costa
Karen Brasil Ruschel
Matheus Carvalho Alves Nogueira
Neimy Ramos de Oliveira
Roberta Pozza
Saionara Cristina Francisco
Thalita Martins Lage
Yuri Carlotto Ramires
Maria do Carmo Barros de Melo
Daniella Nunes Pereira
Zilma Silveira Nogueira Reis
José Miguel Chatkin
Milena Soriano Marcolino
Lilian Martins Oliveira Diniz
Cristiane Dos Santos Dias
André Soares de Moura Costa
Bárbara Lopes Farace
Carla Thais Candida Alves da Silva
Fernando Anschau
Fernando Graça Aranha
author_role author
author2 Guilherme Fagundes Nascimento
Helena Duani
Jamille Hemétrio Salles Martins Costa
Karen Brasil Ruschel
Matheus Carvalho Alves Nogueira
Neimy Ramos de Oliveira
Roberta Pozza
Saionara Cristina Francisco
Thalita Martins Lage
Yuri Carlotto Ramires
Maria do Carmo Barros de Melo
Daniella Nunes Pereira
Zilma Silveira Nogueira Reis
José Miguel Chatkin
Milena Soriano Marcolino
Lilian Martins Oliveira Diniz
Cristiane Dos Santos Dias
André Soares de Moura Costa
Bárbara Lopes Farace
Carla Thais Candida Alves da Silva
Fernando Anschau
Fernando Graça Aranha
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Priscila Menezes Ferriliu
Guilherme Fagundes Nascimento
Helena Duani
Jamille Hemétrio Salles Martins Costa
Karen Brasil Ruschel
Matheus Carvalho Alves Nogueira
Neimy Ramos de Oliveira
Roberta Pozza
Saionara Cristina Francisco
Thalita Martins Lage
Yuri Carlotto Ramires
Maria do Carmo Barros de Melo
Daniella Nunes Pereira
Zilma Silveira Nogueira Reis
José Miguel Chatkin
Milena Soriano Marcolino
Lilian Martins Oliveira Diniz
Cristiane Dos Santos Dias
André Soares de Moura Costa
Bárbara Lopes Farace
Carla Thais Candida Alves da Silva
Fernando Anschau
Fernando Graça Aranha
dc.subject.por.fl_str_mv Pandemic
Covid-19
Children
Adolescent
topic Pandemic
Covid-19
Children
Adolescent
Pandemias
Covid-19
Crianças
Adolescentes
dc.subject.other.pt_BR.fl_str_mv Pandemias
Covid-19
Crianças
Adolescentes
description Introduction:Children and adolescents with Covid-19 have been shown lower mortality less intense symptoms when compared to adults, but studies in Brazil have been based on the compulsory notifying system only. Objective: To analyse clinical, laboratory, radiological characteristics and outcomes of hospitalized patients under 20 years with Covid-19. Methods: Cases series of hospitalized patients with confirmed Covid-19 under 20 years, obtained from a cohort study in 21 hospitals from five states of Brazil.Results: From 36 patients, 20 (55.5%) were adolescentes, 20 (55.5%) were male, 18 (50.0%) had comorbidities, 2 were pregnant and in 7 (19.4%), initial symptoms occurred during hospitalization for other causes, of whom 3 were possibly infected in the hospital. Fever (61.1%), dyspnea (33.3%) and neurological symptoms (33.0%) were the most common complaints. C-reactive protein was higher than 50mg/L in 16.7% and D-dimer was above the reference limit in 22.2%. Chest X-rays were performed in 20 (55.5%) patients, 9 had abnormalities, and chest tomography in 5. Hospital length of stay ranged from 1-40 days (median 5 [interquartile range 3-10]), 16 (44.4%) needed intensive therapy, 6 (16.7%) required mechanical ventilation and one patient (2.8%) died. Conclusion: In case series patients under 20 years from hospitals from 5 states of Brazil, comorbidities were frequent, and most common symptoms were fever, dyspnea and neurological symptoms. Forty-four percent required intensive therapy, showing that the disease was not as mild as it was expected, and one patient died.
publishDate 2021
dc.date.issued.fl_str_mv 2021-08-09
dc.date.accessioned.fl_str_mv 2023-06-13T20:13:48Z
dc.date.available.fl_str_mv 2023-06-13T20:13:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/54883
dc.identifier.doi.pt_BR.fl_str_mv 10.34117/bjdv7n9-011
dc.identifier.issn.pt_BR.fl_str_mv 25258761
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0001-9755-0364
identifier_str_mv 10.34117/bjdv7n9-011
25258761
url http://hdl.handle.net/1843/54883
https://orcid.org/0000-0001-9755-0364
dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.none.fl_str_mv Brazilian Journal of Development
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv MED - DEPARTAMENTO DE CLÍNICA MÉDICA
MED - DEPARTAMENTO DE GINECOLOGIA OBSTETRÍCIA
MED - DEPARTAMENTO DE PEDIATRIA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
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