1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)

Detalhes bibliográficos
Autor(a) principal: Goutam Brahmachari
Data de Publicação: 2017
Outros Autores: Avijit Mondal, Sadhan Mondal, Luzia Valentina Modolo, Angelo de Fatima, Ana Lúcia Tasca Góis Ruiz, João Ernesto de Carvalho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/64980
https://orcid.org/0000-0003-2344-5590
https://orcid.org/0000-0003-3705-0856
https://orcid.org/0000-0001-9925-6281
https://orcid.org/0000-0002-8033-0434
https://orcid.org/0000-0002-0844-8702
Resumo: A biologically relevant natural pigment, 1,6-dihydroxy-3-methyl-9,10-anthraquinone 1, widely produced by fungus from Phoma genus, has been isolated from Cassia sophera Linn. (Caesalpiniaceae) roots and subjected to detailed spectral studies, including 1D- and 2D-NMR. The compound 1 inhibits the proliferation of several cancer cell lines at different extents, showing minor effects on the growth of non-tumorogenic keratinocyte cells.
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spelling 2024-02-29T17:18:00Z2024-02-29T17:18:00Z201758B125112550376-4699http://hdl.handle.net/1843/64980https://orcid.org/0000-0003-2344-5590https://orcid.org/0000-0003-3705-0856https://orcid.org/0000-0001-9925-6281https://orcid.org/0000-0002-8033-0434https://orcid.org/0000-0002-0844-8702A biologically relevant natural pigment, 1,6-dihydroxy-3-methyl-9,10-anthraquinone 1, widely produced by fungus from Phoma genus, has been isolated from Cassia sophera Linn. (Caesalpiniaceae) roots and subjected to detailed spectral studies, including 1D- and 2D-NMR. The compound 1 inhibits the proliferation of several cancer cell lines at different extents, showing minor effects on the growth of non-tumorogenic keratinocyte cells.engUniversidade Federal de Minas GeraisUFMGBrasilICB - DEPARTAMENTO DE BOTÂNICAICX - DEPARTAMENTO DE QUÍMICAIndian Journal of Chemistry - Section BAntraquinonasAgentes antineoplásicosEspectroscopia de ressonância nuclearRessonância magnética nuclearCesalpinaceaCromatografia em gel1,6-Dihydroxy-3-methyl-9,10-anthraquinoneCassia sopheraSpectral studiesAnti-cancer activity1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://op.niscair.res.in/index.php/IJCB/aboutGoutam BrahmachariAvijit MondalSadhan MondalLuzia Valentina ModoloAngelo de FatimaAna Lúcia Tasca Góis RuizJoão Ernesto de Carvalhoapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/64980/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINAL1,6-Dihydroxy-3-methyl-9,10-anthraquinone An anti-cancerous natural.pdf1,6-Dihydroxy-3-methyl-9,10-anthraquinone An anti-cancerous natural.pdfapplication/pdf139240https://repositorio.ufmg.br/bitstream/1843/64980/2/1%2c6-Dihydroxy-3-methyl-9%2c10-anthraquinone%20An%20anti-cancerous%20natural.pdf4385a6462f282d946a6e3de839ba41b0MD521843/649802024-02-29 14:18:00.845oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2024-02-29T17:18Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
title 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
spellingShingle 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
Goutam Brahmachari
1,6-Dihydroxy-3-methyl-9,10-anthraquinone
Cassia sophera
Spectral studies
Anti-cancer activity
Antraquinonas
Agentes antineoplásicos
Espectroscopia de ressonância nuclear
Ressonância magnética nuclear
Cesalpinacea
Cromatografia em gel
title_short 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
title_full 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
title_fullStr 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
title_full_unstemmed 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
title_sort 1,6-Dihydroxy-3-methyl-9,10-anthraquinone: an anti-cancerous natural pigment from Cassia sophera Linn. (Caesalpiniaceae)
author Goutam Brahmachari
author_facet Goutam Brahmachari
Avijit Mondal
Sadhan Mondal
Luzia Valentina Modolo
Angelo de Fatima
Ana Lúcia Tasca Góis Ruiz
João Ernesto de Carvalho
author_role author
author2 Avijit Mondal
Sadhan Mondal
Luzia Valentina Modolo
Angelo de Fatima
Ana Lúcia Tasca Góis Ruiz
João Ernesto de Carvalho
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Goutam Brahmachari
Avijit Mondal
Sadhan Mondal
Luzia Valentina Modolo
Angelo de Fatima
Ana Lúcia Tasca Góis Ruiz
João Ernesto de Carvalho
dc.subject.por.fl_str_mv 1,6-Dihydroxy-3-methyl-9,10-anthraquinone
Cassia sophera
Spectral studies
Anti-cancer activity
topic 1,6-Dihydroxy-3-methyl-9,10-anthraquinone
Cassia sophera
Spectral studies
Anti-cancer activity
Antraquinonas
Agentes antineoplásicos
Espectroscopia de ressonância nuclear
Ressonância magnética nuclear
Cesalpinacea
Cromatografia em gel
dc.subject.other.pt_BR.fl_str_mv Antraquinonas
Agentes antineoplásicos
Espectroscopia de ressonância nuclear
Ressonância magnética nuclear
Cesalpinacea
Cromatografia em gel
description A biologically relevant natural pigment, 1,6-dihydroxy-3-methyl-9,10-anthraquinone 1, widely produced by fungus from Phoma genus, has been isolated from Cassia sophera Linn. (Caesalpiniaceae) roots and subjected to detailed spectral studies, including 1D- and 2D-NMR. The compound 1 inhibits the proliferation of several cancer cell lines at different extents, showing minor effects on the growth of non-tumorogenic keratinocyte cells.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2024-02-29T17:18:00Z
dc.date.available.fl_str_mv 2024-02-29T17:18:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/64980
dc.identifier.issn.pt_BR.fl_str_mv 0376-4699
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0003-2344-5590
https://orcid.org/0000-0003-3705-0856
https://orcid.org/0000-0001-9925-6281
https://orcid.org/0000-0002-8033-0434
https://orcid.org/0000-0002-0844-8702
identifier_str_mv 0376-4699
url http://hdl.handle.net/1843/64980
https://orcid.org/0000-0003-2344-5590
https://orcid.org/0000-0003-3705-0856
https://orcid.org/0000-0001-9925-6281
https://orcid.org/0000-0002-8033-0434
https://orcid.org/0000-0002-0844-8702
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Indian Journal of Chemistry - Section B
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv ICB - DEPARTAMENTO DE BOTÂNICA
ICX - DEPARTAMENTO DE QUÍMICA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
bitstream.url.fl_str_mv https://repositorio.ufmg.br/bitstream/1843/64980/1/License.txt
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