Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil

Detalhes bibliográficos
Autor(a) principal: Flávia Cristina Moura Gualberto
Data de Publicação: 2023
Outros Autores: Camila Rafaela dos Santos, Cassia Rodrigues Lima Ferreira, Josiane Moreira da Costa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.15343/0104-7809.202347e1452020P
http://hdl.handle.net/1843/76650
https://orcid.org/0000-0002-4804-6556
https://orcid.org/0000-0002-6849-8349
https://orcid.org/0000-0001-6187-2011
https://orcid.org/0000-0001-6097-6994
Resumo: Omeprazole is the most prescribed proton pump inhibitor in Brazil and is indicated for the treatment of diseases caused by gastroesophageal reflux, peptic ulcer, erosive esophagitis, eradication of Helicobacter pylori, Zollinger-Ellison syndrome, gastrinomas, gastritis, and hypersecretory disorders, as well as peptic ulcer prevention. The indiscriminate and unnecessary use, mainly by the elderly, is an important public health issue to be addressed. Despite the existence of indiscriminate use of omeprazole being known, there is a need to verify how this medication is prescribed in the context of the Unified Health System (UHS) in Brazil. In addition, it is believed that studies that aim to analyze the prescription of omeprazole in a pharmacoeconomic way can contribute to the review or implementation of guidelines and protocols involving the use of this drug. The objective of this study was to characterize and perform a pharmacoeconomic analysis of the use of omeprazole in a Primary Healthcare Centers (PHC) in Minas Gerais, Brazil. This is a descriptive study analyzing the prescriptions of 41 elderly patients treated in the period of April/May 2018 and the following variables were identified: age, sex, dose, indication, endoscopy, other medications in use, and cost of treatment. In the pharmacoeconomic analysis, the average cost of the amount of omeprazole prescribed per patient was calculated and whether or not endoscopy was performed was considered. In the studied population, 29 (70.3%) were female with a median age: 69 years. Only in 4 medical records (9.8%) was there indication for use, and 18 (43.9%) patients had been using omeprazole for more than two years and 7 (17.1%) for more than five years. Only 3 (7.3%) patients underwent endoscopy, and 371 months-worth of omeprazole were used, totaling a financial value of R$35,657.23. The findings suggest long-term prescriptions and no record of their indication on medical records. The cost related to prescriptions could be optimized by performing endoscopy and discontinuing its use when no indication is found.
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spelling Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do BrasilPharmacoeconomic analysis of the use of omeprazole by elderly patients in one of the primary healthcare centers in BrazilIdososOmeprazolPrescriçãoErros de medicaçãoFarmacoeconomiaIdosoOmeprazolPrescriçõesErros de medicaçãoFarmacoeconomiaOmeprazole is the most prescribed proton pump inhibitor in Brazil and is indicated for the treatment of diseases caused by gastroesophageal reflux, peptic ulcer, erosive esophagitis, eradication of Helicobacter pylori, Zollinger-Ellison syndrome, gastrinomas, gastritis, and hypersecretory disorders, as well as peptic ulcer prevention. The indiscriminate and unnecessary use, mainly by the elderly, is an important public health issue to be addressed. Despite the existence of indiscriminate use of omeprazole being known, there is a need to verify how this medication is prescribed in the context of the Unified Health System (UHS) in Brazil. In addition, it is believed that studies that aim to analyze the prescription of omeprazole in a pharmacoeconomic way can contribute to the review or implementation of guidelines and protocols involving the use of this drug. The objective of this study was to characterize and perform a pharmacoeconomic analysis of the use of omeprazole in a Primary Healthcare Centers (PHC) in Minas Gerais, Brazil. This is a descriptive study analyzing the prescriptions of 41 elderly patients treated in the period of April/May 2018 and the following variables were identified: age, sex, dose, indication, endoscopy, other medications in use, and cost of treatment. In the pharmacoeconomic analysis, the average cost of the amount of omeprazole prescribed per patient was calculated and whether or not endoscopy was performed was considered. In the studied population, 29 (70.3%) were female with a median age: 69 years. Only in 4 medical records (9.8%) was there indication for use, and 18 (43.9%) patients had been using omeprazole for more than two years and 7 (17.1%) for more than five years. Only 3 (7.3%) patients underwent endoscopy, and 371 months-worth of omeprazole were used, totaling a financial value of R$35,657.23. The findings suggest long-term prescriptions and no record of their indication on medical records. The cost related to prescriptions could be optimized by performing endoscopy and discontinuing its use when no indication is found.O omeprazol é inibidor de bomba de prótons mais prescrito no Brasil e é indicado para o tratamento de doenças por refluxos gastroesofágicos, úlcera péptica, esofagite erosiva, erradicação de Helicobacter pylori, síndrome de Zollinger-Ellison, gastrinomas, gastrite e distúrbios hipersecretores e prevenção de úlcera péptica. O uso indiscriminado e desnecessário, principalmente por idosos, é uma importante questão de saúde pública a ser tratada. Apesar de ser conhecida a existência do uso indiscriminado do omeprazol, identifica-se a necessidade de se verificar como ocorre a prescrição desse medicamento no contexto do Sistema Único de Saúde (SUS) do Brasil. Além disso, acredita-se que estudos que analisam de modo famacoeconômico a prescrição do omeprazol podem contribuir para a revisão ou implementação de diretrizes e protocolos que envolvam o uso desse medicamento. O objetivo foi caracterizar e realizar análise farmacoeconômica do uso do omeprazol em Unidade de Atenção Primária a Saúde (UAPS) em Minas Gerais, Brasil. Trata-se de estudo descritivo com análise das prescrições de 41 pacientes idosos atendidos no período de abril/maio de 2018 e foram identificadas as seguintes variáveis: idade, sexo, dose, indicação, realização de endoscopia, demais medicamentos em uso e custo do tratamento. Na análise farmacoeconômica realizou-se o cálculo do custo médio da quantidade de omeprazol prescrita por paciente e considerou-se a realização ou não de endoscopia. Na população estudada, 29 (70,3%) do sexo feminino com mediana de idade: 69 anos. Apenas em 4 prontuários (9,8%) havia indicação para uso e em 18 (43,9%) pacientes, a utilização era feita há mais de dois anos e em 7 (17,1%) a mais de cinco anos. Apenas 3 (7,3%) realizaram endoscopia e foram utilizados 371 meses totalizando um valor financeiro de R$35.657,23. Os achados sugerem prescrições em longo prazo e sem registro da indicação em prontuário. O custo referente às prescrições poderia ser otimizado com a realização de endoscopia e suspensão do uso, quando constatada ausência de indicação.Universidade Federal de Minas GeraisBrasilFARMACIA - FACULDADE DE FARMACIAUFMG2024-09-18T19:57:48Z2024-09-18T19:57:48Z2023info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdfhttps://doi.org/10.15343/0104-7809.202347e1452020P1980-3990http://hdl.handle.net/1843/76650https://orcid.org/0000-0002-4804-6556https://orcid.org/0000-0002-6849-8349https://orcid.org/0000-0001-6187-2011https://orcid.org/0000-0001-6097-6994porO Mundo da SaúdeFlávia Cristina Moura GualbertoCamila Rafaela dos SantosCassia Rodrigues Lima FerreiraJosiane Moreira da Costainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2024-09-18T19:57:49Zoai:repositorio.ufmg.br:1843/76650Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2024-09-18T19:57:49Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
Pharmacoeconomic analysis of the use of omeprazole by elderly patients in one of the primary healthcare centers in Brazil
title Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
spellingShingle Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
Flávia Cristina Moura Gualberto
Idosos
Omeprazol
Prescrição
Erros de medicação
Farmacoeconomia
Idoso
Omeprazol
Prescrições
Erros de medicação
Farmacoeconomia
title_short Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
title_full Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
title_fullStr Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
title_full_unstemmed Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
title_sort Análise farmacoeconômica do uso de omeprazol por idosos em uma das unidades básicas de saúde do Brasil
author Flávia Cristina Moura Gualberto
author_facet Flávia Cristina Moura Gualberto
Camila Rafaela dos Santos
Cassia Rodrigues Lima Ferreira
Josiane Moreira da Costa
author_role author
author2 Camila Rafaela dos Santos
Cassia Rodrigues Lima Ferreira
Josiane Moreira da Costa
author2_role author
author
author
dc.contributor.author.fl_str_mv Flávia Cristina Moura Gualberto
Camila Rafaela dos Santos
Cassia Rodrigues Lima Ferreira
Josiane Moreira da Costa
dc.subject.por.fl_str_mv Idosos
Omeprazol
Prescrição
Erros de medicação
Farmacoeconomia
Idoso
Omeprazol
Prescrições
Erros de medicação
Farmacoeconomia
topic Idosos
Omeprazol
Prescrição
Erros de medicação
Farmacoeconomia
Idoso
Omeprazol
Prescrições
Erros de medicação
Farmacoeconomia
description Omeprazole is the most prescribed proton pump inhibitor in Brazil and is indicated for the treatment of diseases caused by gastroesophageal reflux, peptic ulcer, erosive esophagitis, eradication of Helicobacter pylori, Zollinger-Ellison syndrome, gastrinomas, gastritis, and hypersecretory disorders, as well as peptic ulcer prevention. The indiscriminate and unnecessary use, mainly by the elderly, is an important public health issue to be addressed. Despite the existence of indiscriminate use of omeprazole being known, there is a need to verify how this medication is prescribed in the context of the Unified Health System (UHS) in Brazil. In addition, it is believed that studies that aim to analyze the prescription of omeprazole in a pharmacoeconomic way can contribute to the review or implementation of guidelines and protocols involving the use of this drug. The objective of this study was to characterize and perform a pharmacoeconomic analysis of the use of omeprazole in a Primary Healthcare Centers (PHC) in Minas Gerais, Brazil. This is a descriptive study analyzing the prescriptions of 41 elderly patients treated in the period of April/May 2018 and the following variables were identified: age, sex, dose, indication, endoscopy, other medications in use, and cost of treatment. In the pharmacoeconomic analysis, the average cost of the amount of omeprazole prescribed per patient was calculated and whether or not endoscopy was performed was considered. In the studied population, 29 (70.3%) were female with a median age: 69 years. Only in 4 medical records (9.8%) was there indication for use, and 18 (43.9%) patients had been using omeprazole for more than two years and 7 (17.1%) for more than five years. Only 3 (7.3%) patients underwent endoscopy, and 371 months-worth of omeprazole were used, totaling a financial value of R$35,657.23. The findings suggest long-term prescriptions and no record of their indication on medical records. The cost related to prescriptions could be optimized by performing endoscopy and discontinuing its use when no indication is found.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024-09-18T19:57:48Z
2024-09-18T19:57:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.15343/0104-7809.202347e1452020P
1980-3990
http://hdl.handle.net/1843/76650
https://orcid.org/0000-0002-4804-6556
https://orcid.org/0000-0002-6849-8349
https://orcid.org/0000-0001-6187-2011
https://orcid.org/0000-0001-6097-6994
url https://doi.org/10.15343/0104-7809.202347e1452020P
http://hdl.handle.net/1843/76650
https://orcid.org/0000-0002-4804-6556
https://orcid.org/0000-0002-6849-8349
https://orcid.org/0000-0001-6187-2011
https://orcid.org/0000-0001-6097-6994
identifier_str_mv 1980-3990
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv O Mundo da Saúde
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
FARMACIA - FACULDADE DE FARMACIA
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
Brasil
FARMACIA - FACULDADE DE FARMACIA
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
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