Potentially inappropriate medication use among elderly patients from a brazilian general hospital.

Detalhes bibliográficos
Autor(a) principal: Daiane Celly Guimarães e Silva
Data de Publicação: 2016
Outros Autores: Mariana Linhares Pereira, Danielly Botelho Soares, Antônio Ignácio Loyola-filho, Mariana Martins Gonzaga do Nascimento
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://dx.doi.org/10.14450/2318-9312.v28.e1.a2016.pp27-32
http://hdl.handle.net/1843/59599
Resumo: The aim of this study was to determine the profile of the pharmacotherapy used by hospitalized elderly. A cross-sectional study was conducted at a Brazilian charitable general hospital. Drug prescriptions for hospitalized elderly patients (age≥60 years), dated from May to September 2010, were the source of data for this study and retrospectively analyzed (n=1,783). Polypharmacy (use of 5 or more drugs) and potentially inappropriate medications (PIMs – according to the Beers Criteria) were identified. Associations between sex, age, admission for cardiovascular disease or hospital stay and polypharmacy or PIM prescription were studied using univariate analysis (Pearson’s Chi-square test). The association between polypharmacy and PIM prescription was also evaluated. A total of 204 elderly were hospitalized (mean age = 75 years) during the study period. The most commonly prescribed drugs acted on the cardiovascular system (29%) and the alimentary tract and metabolism (26%). Around 90% of the elderly were submitted to polypharmacy and 59% had, at least, one prescription of PIMs. A hospital stay of five days or more was associated with polypharmacy and PIM prescription. This study revealed a worrying drug utilization profile of high PIM use and polypharmacy practice. There is a need to implement strategies to improve geriatric prescribing
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spelling 2023-10-18T15:14:05Z2023-10-18T15:14:05Z20162812732http://dx.doi.org/10.14450/2318-9312.v28.e1.a2016.pp27-322318-9312http://hdl.handle.net/1843/59599The aim of this study was to determine the profile of the pharmacotherapy used by hospitalized elderly. A cross-sectional study was conducted at a Brazilian charitable general hospital. Drug prescriptions for hospitalized elderly patients (age≥60 years), dated from May to September 2010, were the source of data for this study and retrospectively analyzed (n=1,783). Polypharmacy (use of 5 or more drugs) and potentially inappropriate medications (PIMs – according to the Beers Criteria) were identified. Associations between sex, age, admission for cardiovascular disease or hospital stay and polypharmacy or PIM prescription were studied using univariate analysis (Pearson’s Chi-square test). The association between polypharmacy and PIM prescription was also evaluated. A total of 204 elderly were hospitalized (mean age = 75 years) during the study period. The most commonly prescribed drugs acted on the cardiovascular system (29%) and the alimentary tract and metabolism (26%). Around 90% of the elderly were submitted to polypharmacy and 59% had, at least, one prescription of PIMs. A hospital stay of five days or more was associated with polypharmacy and PIM prescription. This study revealed a worrying drug utilization profile of high PIM use and polypharmacy practice. There is a need to implement strategies to improve geriatric prescribingO objetivo deste estudo foi determinar o perfil da farmacoterapia utilizada por idosos hospitalizados. Foi realizado um estudo transversal em hospital brasileiro geral filantrópico. As prescrições de pacientes idosos hospitalizados (idade ≥ 60 anos), datadas a partir de maio a setembro de 2010 foram a fonte de dados para este estudo e foram analisadas retrospectivamente (n=1.783). A prática de polifarmácia (consumo de 5 ou mais medicamentos) e uso de medicamentos potencialmente inadequados (MPI - de acordo com o critério de Beers) foram identificados. As associações entre gênero, idade, admissão para doença cardiovascular ou tempo de estadia hospitalar e polifarmácia ou uso de MPI foram analisadas por meio de análise univariada (teste do qui-quadrado de Pearson). A associação entre polifarmácia e MPI prescrição também foi avaliada. Durante o período do estudo, 204 idosos foram hospitalizados (idade média=75 anos). Os medicamentos mais prescritos agiam sobre o sistema cardiovascular (29%) e sistema digestório e metabolismo (26%). Cerca de 90% dos idosos praticavam polifarmácia e 59% usavam pelo menos um MPI. A estada hospitalar de cinco dias ou mais foi associada a polifarmácia e uso de PIM. Este estudo permitiu o diagnóstico de um perfil de utilização de medicamentos preocupante. Assim, surge a necessidade de implementação de estratégias para melhorar a prescrição geriátrica.engUniversidade Federal de Minas GeraisUFMGBrasilFAR - DEPARTAMENTO DE PRODUTOS FARMACÊUTICOSInfarma - Ciências FarmacêuticasIdososMedicamentos - PrescriçãoPolifarmáciaEnvelhecimentoFarmacoepidemiologiaAgedInappropriate prescribingPolypharmacyAgingPharmacoepidemiologyPotentially inappropriate medication use among elderly patients from a brazilian general hospital.Uso de medicamentos potencialmente inadequados entre idosos em um hospital geral brasileiro.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://revistas.cff.org.br/?journal=infarma&page=article&op=view&path%5B%5D=1257Daiane Celly Guimarães e SilvaMariana Linhares PereiraDanielly Botelho SoaresAntônio Ignácio Loyola-filhoMariana Martins Gonzaga do Nascimentoapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/59599/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALPotentially inappropriate medication use among.pdfPotentially inappropriate medication use among.pdfapplication/pdf519753https://repositorio.ufmg.br/bitstream/1843/59599/2/Potentially%20inappropriate%20medication%20use%20among.pdf49858dc6c1beed39884a9f30a35d59c2MD521843/595992023-10-18 17:24:46.029oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-10-18T20:24:46Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
dc.title.alternative.pt_BR.fl_str_mv Uso de medicamentos potencialmente inadequados entre idosos em um hospital geral brasileiro.
title Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
spellingShingle Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
Daiane Celly Guimarães e Silva
Aged
Inappropriate prescribing
Polypharmacy
Aging
Pharmacoepidemiology
Idosos
Medicamentos - Prescrição
Polifarmácia
Envelhecimento
Farmacoepidemiologia
title_short Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
title_full Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
title_fullStr Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
title_full_unstemmed Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
title_sort Potentially inappropriate medication use among elderly patients from a brazilian general hospital.
author Daiane Celly Guimarães e Silva
author_facet Daiane Celly Guimarães e Silva
Mariana Linhares Pereira
Danielly Botelho Soares
Antônio Ignácio Loyola-filho
Mariana Martins Gonzaga do Nascimento
author_role author
author2 Mariana Linhares Pereira
Danielly Botelho Soares
Antônio Ignácio Loyola-filho
Mariana Martins Gonzaga do Nascimento
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Daiane Celly Guimarães e Silva
Mariana Linhares Pereira
Danielly Botelho Soares
Antônio Ignácio Loyola-filho
Mariana Martins Gonzaga do Nascimento
dc.subject.por.fl_str_mv Aged
Inappropriate prescribing
Polypharmacy
Aging
Pharmacoepidemiology
topic Aged
Inappropriate prescribing
Polypharmacy
Aging
Pharmacoepidemiology
Idosos
Medicamentos - Prescrição
Polifarmácia
Envelhecimento
Farmacoepidemiologia
dc.subject.other.pt_BR.fl_str_mv Idosos
Medicamentos - Prescrição
Polifarmácia
Envelhecimento
Farmacoepidemiologia
description The aim of this study was to determine the profile of the pharmacotherapy used by hospitalized elderly. A cross-sectional study was conducted at a Brazilian charitable general hospital. Drug prescriptions for hospitalized elderly patients (age≥60 years), dated from May to September 2010, were the source of data for this study and retrospectively analyzed (n=1,783). Polypharmacy (use of 5 or more drugs) and potentially inappropriate medications (PIMs – according to the Beers Criteria) were identified. Associations between sex, age, admission for cardiovascular disease or hospital stay and polypharmacy or PIM prescription were studied using univariate analysis (Pearson’s Chi-square test). The association between polypharmacy and PIM prescription was also evaluated. A total of 204 elderly were hospitalized (mean age = 75 years) during the study period. The most commonly prescribed drugs acted on the cardiovascular system (29%) and the alimentary tract and metabolism (26%). Around 90% of the elderly were submitted to polypharmacy and 59% had, at least, one prescription of PIMs. A hospital stay of five days or more was associated with polypharmacy and PIM prescription. This study revealed a worrying drug utilization profile of high PIM use and polypharmacy practice. There is a need to implement strategies to improve geriatric prescribing
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2023-10-18T15:14:05Z
dc.date.available.fl_str_mv 2023-10-18T15:14:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/59599
dc.identifier.doi.pt_BR.fl_str_mv http://dx.doi.org/10.14450/2318-9312.v28.e1.a2016.pp27-32
dc.identifier.issn.pt_BR.fl_str_mv 2318-9312
url http://dx.doi.org/10.14450/2318-9312.v28.e1.a2016.pp27-32
http://hdl.handle.net/1843/59599
identifier_str_mv 2318-9312
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Infarma - Ciências Farmacêuticas
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv FAR - DEPARTAMENTO DE PRODUTOS FARMACÊUTICOS
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
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