Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.1371/journal.pntd.0004672 http://hdl.handle.net/1843/57710 https://orcid.org/0000-0003-0544-309X |
Resumo: | Background:Schistosomal myeloradiculopathy (SMR), the most severe and disabling ectopic form of Schistosoma mansoni infection, is caused by embolized ova eliciting local inflammation in the spinal cord and nerve roots. The treatment involves the use of praziquantel and long term corticotherapy. The assessment of therapeutic response relies on neurological exami nation. Supplementary electrophysiological exams may improve prediction and monitoring of functional outcome. Vestibular evoked myogenic potential (VEMP) triggered by galvanic vestibular stimulation (GVS) is a simple, safe, low-cost and noninvasive electrophysiological technique that has been used to test the vestibulospinal tract in motor myelopathies.This paper reports the results of VEMP with GVS in patients with SMR.Methods:A cross-sectional comparative study enrolled 22 patients with definite SMR and 22 healthy controls that were submitted to clinical, neurological examination and GVS. Galvanic stimulus was applied in the mastoid bones in a transcranial configuration for testing VEMP, which was recorded by electromyography (EMG) in the gastrocnemii muscles.The VEMP variables of interest were blindly measured by two independent examiners.They were the short-latency (SL) and the medium-latency (ML) components of the biphasic EMG wave. Results: VEMP showed the components SL (p = 0.001) and ML (p<0.001) delayed in SMR compared to controls. The delay of SL (p = 0.010) and of ML (p = 0.020) was associated with gait dysfunction.Conclusion: VEMP triggered by GVS identified alterations in patients with SMR and provided additional functional information that justifies its use as a supplementary test in motor myelopathies. |
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2023-08-10T19:54:37Z2023-08-10T19:54:37Z2016-04-29114https://doi.org/10.1371/journal.pntd.00046721932-6203http://hdl.handle.net/1843/57710https://orcid.org/0000-0003-0544-309XBackground:Schistosomal myeloradiculopathy (SMR), the most severe and disabling ectopic form of Schistosoma mansoni infection, is caused by embolized ova eliciting local inflammation in the spinal cord and nerve roots. The treatment involves the use of praziquantel and long term corticotherapy. The assessment of therapeutic response relies on neurological exami nation. Supplementary electrophysiological exams may improve prediction and monitoring of functional outcome. Vestibular evoked myogenic potential (VEMP) triggered by galvanic vestibular stimulation (GVS) is a simple, safe, low-cost and noninvasive electrophysiological technique that has been used to test the vestibulospinal tract in motor myelopathies.This paper reports the results of VEMP with GVS in patients with SMR.Methods:A cross-sectional comparative study enrolled 22 patients with definite SMR and 22 healthy controls that were submitted to clinical, neurological examination and GVS. Galvanic stimulus was applied in the mastoid bones in a transcranial configuration for testing VEMP, which was recorded by electromyography (EMG) in the gastrocnemii muscles.The VEMP variables of interest were blindly measured by two independent examiners.They were the short-latency (SL) and the medium-latency (ML) components of the biphasic EMG wave. Results: VEMP showed the components SL (p = 0.001) and ML (p<0.001) delayed in SMR compared to controls. The delay of SL (p = 0.010) and of ML (p = 0.020) was associated with gait dysfunction.Conclusion: VEMP triggered by GVS identified alterations in patients with SMR and provided additional functional information that justifies its use as a supplementary test in motor myelopathies.engUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE CLÍNICA MÉDICAMED - DEPARTAMENTO DE FONOAUDIOLOGIAMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIAPLOS Neglected Tropical DiseasesNeuroesquistossomoseEsquistossomose mansoniPotenciais evocados vestibularesSchistosomal myeloradiculopathySchistosoma mansoni infectionGalvanic Vestibular StimulationVestibular Evoked Myogenic PotentialsVestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://journals.plos.org/plosntds/article/authors?id=10.1371/journal.pntd.0004672Júlia Fonseca de Morais CaporaliDenise Utsch GonçalvesLudimila LabancaLeonardo Dornas de OliveiraGuilherme Vaz de Melo TrindadeThiago de Almeida PereiraPedro Henrique Diniz CunhaMarina Santos Falci MourãoJosé Roberto Lambertucciapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/57710/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALVestibular Evoked Myogenic Potential (VEMP) Triggered by Galvanic Vestibular Stimulation (GVS) A Promising Tool to Assess Spinal Cord Function in Schistosomal Myeloradiculopathy pdfa.pdfVestibular Evoked Myogenic Potential (VEMP) Triggered by Galvanic Vestibular Stimulation (GVS) A Promising Tool to Assess Spinal Cord Function in Schistosomal Myeloradiculopathy pdfa.pdfapplication/pdf751159https://repositorio.ufmg.br/bitstream/1843/57710/2/Vestibular%20Evoked%20Myogenic%20Potential%20%28VEMP%29%20Triggered%20by%20Galvanic%20Vestibular%20Stimulation%20%28GVS%29%20A%20Promising%20Tool%20to%20Assess%20Spinal%20Cord%20Function%20in%20Schistosomal%20Myeloradiculopathy%20pdfa.pdfe9002fe48807225a87200e71cc7f2fe1MD521843/577102023-08-10 17:54:00.357oai:repositorio.ufmg.br:1843/57710TElDRU7vv71BIERFIERJU1RSSUJVSe+/ve+/vU8gTu+/vU8tRVhDTFVTSVZBIERPIFJFUE9TSVTvv71SSU8gSU5TVElUVUNJT05BTCBEQSBVRk1HCiAKCkNvbSBhIGFwcmVzZW50Ye+/ve+/vW8gZGVzdGEgbGljZW7vv71hLCB2b2Pvv70gKG8gYXV0b3IgKGVzKSBvdSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGRlIGF1dG9yKSBjb25jZWRlIGFvIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRk1HIChSSS1VRk1HKSBvIGRpcmVpdG8gbu+/vW8gZXhjbHVzaXZvIGUgaXJyZXZvZ++/vXZlbCBkZSByZXByb2R1emlyIGUvb3UgZGlzdHJpYnVpciBhIHN1YSBwdWJsaWNh77+977+9byAoaW5jbHVpbmRvIG8gcmVzdW1vKSBwb3IgdG9kbyBvIG11bmRvIG5vIGZvcm1hdG8gaW1wcmVzc28gZSBlbGV0cu+/vW5pY28gZSBlbSBxdWFscXVlciBtZWlvLCBpbmNsdWluZG8gb3MgZm9ybWF0b3Mg77+9dWRpbyBvdSB277+9ZGVvLgoKVm9j77+9IGRlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zvv710aWNhIGRlIGNvcHlyaWdodCBkYSBlZGl0b3JhIGRvIHNldSBkb2N1bWVudG8gZSBxdWUgY29uaGVjZSBlIGFjZWl0YSBhcyBEaXJldHJpemVzIGRvIFJJLVVGTUcuCgpWb2Pvv70gY29uY29yZGEgcXVlIG8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVGTUcgcG9kZSwgc2VtIGFsdGVyYXIgbyBjb250Ze+/vWRvLCB0cmFuc3BvciBhIHN1YSBwdWJsaWNh77+977+9byBwYXJhIHF1YWxxdWVyIG1laW8gb3UgZm9ybWF0byBwYXJhIGZpbnMgZGUgcHJlc2VydmHvv73vv71vLgoKVm9j77+9IHRhbWLvv71tIGNvbmNvcmRhIHF1ZSBvIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRk1HIHBvZGUgbWFudGVyIG1haXMgZGUgdW1hIGPvv71waWEgZGUgc3VhIHB1YmxpY2Hvv73vv71vIHBhcmEgZmlucyBkZSBzZWd1cmFu77+9YSwgYmFjay11cCBlIHByZXNlcnZh77+977+9by4KClZvY++/vSBkZWNsYXJhIHF1ZSBhIHN1YSBwdWJsaWNh77+977+9byDvv70gb3JpZ2luYWwgZSBxdWUgdm9j77+9IHRlbSBvIHBvZGVyIGRlIGNvbmNlZGVyIG9zIGRpcmVpdG9zIGNvbnRpZG9zIG5lc3RhIGxpY2Vu77+9YS4gVm9j77+9IHRhbWLvv71tIGRlY2xhcmEgcXVlIG8gZGVw77+9c2l0byBkZSBzdWEgcHVibGljYe+/ve+/vW8gbu+/vW8sIHF1ZSBzZWphIGRlIHNldSBjb25oZWNpbWVudG8sIGluZnJpbmdlIGRpcmVpdG9zIGF1dG9yYWlzIGRlIG5pbmd177+9bS4KCkNhc28gYSBzdWEgcHVibGljYe+/ve+/vW8gY29udGVuaGEgbWF0ZXJpYWwgcXVlIHZvY++/vSBu77+9byBwb3NzdWkgYSB0aXR1bGFyaWRhZGUgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCB2b2Pvv70gZGVjbGFyYSBxdWUgb2J0ZXZlIGEgcGVybWlzc++/vW8gaXJyZXN0cml0YSBkbyBkZXRlbnRvciBkb3MgZGlyZWl0b3MgYXV0b3JhaXMgcGFyYSBjb25jZWRlciBhbyBSZXBvc2l077+9cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZNRyBvcyBkaXJlaXRvcyBhcHJlc2VudGFkb3MgbmVzdGEgbGljZW7vv71hLCBlIHF1ZSBlc3NlIG1hdGVyaWFsIGRlIHByb3ByaWVkYWRlIGRlIHRlcmNlaXJvcyBlc3Tvv70gY2xhcmFtZW50ZSBpZGVudGlmaWNhZG8gZSByZWNvbmhlY2lkbyBubyB0ZXh0byBvdSBubyBjb250Ze+/vWRvIGRhIHB1YmxpY2Hvv73vv71vIG9yYSBkZXBvc2l0YWRhLgoKQ0FTTyBBIFBVQkxJQ0Hvv73vv71PIE9SQSBERVBPU0lUQURBIFRFTkhBIFNJRE8gUkVTVUxUQURPIERFIFVNIFBBVFJPQ++/vU5JTyBPVSBBUE9JTyBERSBVTUEgQUfvv71OQ0lBIERFIEZPTUVOVE8gT1UgT1VUUk8gT1JHQU5JU01PLCBWT0Pvv70gREVDTEFSQSBRVUUgUkVTUEVJVE9VIFRPRE9TIEUgUVVBSVNRVUVSIERJUkVJVE9TIERFIFJFVklT77+9TyBDT01PIFRBTULvv71NIEFTIERFTUFJUyBPQlJJR0Hvv73vv71FUyBFWElHSURBUyBQT1IgQ09OVFJBVE8gT1UgQUNPUkRPLgoKTyBSZXBvc2l077+9cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZNRyBzZSBjb21wcm9tZXRlIGEgaWRlbnRpZmljYXIgY2xhcmFtZW50ZSBvIHNldSBub21lKHMpIG91IG8ocykgbm9tZXMocykgZG8ocykgZGV0ZW50b3IoZXMpIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyBkYSBwdWJsaWNh77+977+9bywgZSBu77+9byBmYXLvv70gcXVhbHF1ZXIgYWx0ZXJh77+977+9bywgYWzvv71tIGRhcXVlbGFzIGNvbmNlZGlkYXMgcG9yIGVzdGEgbGljZW7vv71hLgo=Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-08-10T20:54Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
title |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
spellingShingle |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy Júlia Fonseca de Morais Caporali Schistosomal myeloradiculopathy Schistosoma mansoni infection Galvanic Vestibular Stimulation Vestibular Evoked Myogenic Potentials Neuroesquistossomose Esquistossomose mansoni Potenciais evocados vestibulares |
title_short |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
title_full |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
title_fullStr |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
title_full_unstemmed |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
title_sort |
Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathy |
author |
Júlia Fonseca de Morais Caporali |
author_facet |
Júlia Fonseca de Morais Caporali Denise Utsch Gonçalves Ludimila Labanca Leonardo Dornas de Oliveira Guilherme Vaz de Melo Trindade Thiago de Almeida Pereira Pedro Henrique Diniz Cunha Marina Santos Falci Mourão José Roberto Lambertucci |
author_role |
author |
author2 |
Denise Utsch Gonçalves Ludimila Labanca Leonardo Dornas de Oliveira Guilherme Vaz de Melo Trindade Thiago de Almeida Pereira Pedro Henrique Diniz Cunha Marina Santos Falci Mourão José Roberto Lambertucci |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Júlia Fonseca de Morais Caporali Denise Utsch Gonçalves Ludimila Labanca Leonardo Dornas de Oliveira Guilherme Vaz de Melo Trindade Thiago de Almeida Pereira Pedro Henrique Diniz Cunha Marina Santos Falci Mourão José Roberto Lambertucci |
dc.subject.por.fl_str_mv |
Schistosomal myeloradiculopathy Schistosoma mansoni infection Galvanic Vestibular Stimulation Vestibular Evoked Myogenic Potentials |
topic |
Schistosomal myeloradiculopathy Schistosoma mansoni infection Galvanic Vestibular Stimulation Vestibular Evoked Myogenic Potentials Neuroesquistossomose Esquistossomose mansoni Potenciais evocados vestibulares |
dc.subject.other.pt_BR.fl_str_mv |
Neuroesquistossomose Esquistossomose mansoni Potenciais evocados vestibulares |
description |
Background:Schistosomal myeloradiculopathy (SMR), the most severe and disabling ectopic form of Schistosoma mansoni infection, is caused by embolized ova eliciting local inflammation in the spinal cord and nerve roots. The treatment involves the use of praziquantel and long term corticotherapy. The assessment of therapeutic response relies on neurological exami nation. Supplementary electrophysiological exams may improve prediction and monitoring of functional outcome. Vestibular evoked myogenic potential (VEMP) triggered by galvanic vestibular stimulation (GVS) is a simple, safe, low-cost and noninvasive electrophysiological technique that has been used to test the vestibulospinal tract in motor myelopathies.This paper reports the results of VEMP with GVS in patients with SMR.Methods:A cross-sectional comparative study enrolled 22 patients with definite SMR and 22 healthy controls that were submitted to clinical, neurological examination and GVS. Galvanic stimulus was applied in the mastoid bones in a transcranial configuration for testing VEMP, which was recorded by electromyography (EMG) in the gastrocnemii muscles.The VEMP variables of interest were blindly measured by two independent examiners.They were the short-latency (SL) and the medium-latency (ML) components of the biphasic EMG wave. Results: VEMP showed the components SL (p = 0.001) and ML (p<0.001) delayed in SMR compared to controls. The delay of SL (p = 0.010) and of ML (p = 0.020) was associated with gait dysfunction.Conclusion: VEMP triggered by GVS identified alterations in patients with SMR and provided additional functional information that justifies its use as a supplementary test in motor myelopathies. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016-04-29 |
dc.date.accessioned.fl_str_mv |
2023-08-10T19:54:37Z |
dc.date.available.fl_str_mv |
2023-08-10T19:54:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/57710 |
dc.identifier.doi.pt_BR.fl_str_mv |
https://doi.org/10.1371/journal.pntd.0004672 |
dc.identifier.issn.pt_BR.fl_str_mv |
1932-6203 |
dc.identifier.orcid.pt_BR.fl_str_mv |
https://orcid.org/0000-0003-0544-309X |
url |
https://doi.org/10.1371/journal.pntd.0004672 http://hdl.handle.net/1843/57710 https://orcid.org/0000-0003-0544-309X |
identifier_str_mv |
1932-6203 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
PLOS Neglected Tropical Diseases |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Universidade Federal de Minas Gerais |
dc.publisher.initials.fl_str_mv |
UFMG |
dc.publisher.country.fl_str_mv |
Brasil |
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MED - DEPARTAMENTO DE CLÍNICA MÉDICA MED - DEPARTAMENTO DE FONOAUDIOLOGIA MED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIA |
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Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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UFMG |
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