Influence of detectors efficiency normalization on small animal PET image quality

• Autor(a) principal: Mateus Gesulado Carneirode Santana
• Data de Publicação: 2019
• Outros Autores: Guilherme Cavalcante de Albuquerque Souza, Rodrigo Modesto Gadelha Gontijo, Bruno Melo Mendes, Andréa Vidal Ferreira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: http://hdl.handle.net/1843/57382
• topic: Small Animal PET; Normalization; Image Quality; NEMA NU 4-2008; Tomografia por Emissão de Pósitrons

A small animal positron emission tomograph (LabPET GE 4) image acquisition is done by 1536 independents channels. Differences in the rate counting of each channel must be corrected so as not compromise image quality. Equipment user manual recommends that normalization of the detectors efficiency be made as often as possible and always whenever there are hardware or software parameters changes - included, but not limited to channels parameters adjustments, electronic cards replacements, channels activation or inactivation or software update. This work evaluates the normalization effects on the image quality parameters. PET image acquisition and analysis were performed using recommended parameters by the NEMA NU 4-2008 standards. Image was reconstructed in different ways using different normalization files. The tests performed indicated that the image quality parameters do not vary significantly with different normalization data. Therefore, a high frequency routine of normalizations is not justified, suggesting a periodical frequency of one month for this procedure.