Prevalence of vitamin d deficiency and its relationship with factors associated with recurrent wheezing

• Autor(a) principal: Sílvia Almeida Cardoso
• Data de Publicação: 2019
• Outros Autores: Mirna Peçanha Brito, Luiz Sérgio Silva
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: http://hdl.handle.net/1843/60372
• topic: Asthma; Sibilância; Vitamina D; Asthma; Vitamin D; Respiratory Sounds

Objective: To determine the prevalence of vitamin D defi ciency/insuffi ciency in children 0-18 years of age with recurrent wheezing and/or asthma residing in the microregion of Viçosa, Minas Gerais, Brazil, and treated at a referral center, and to determine its association with major risk factors for wheezing. Methods: A cross-sectional study was performed using a semi-structured questionnaire, which was administered by trained interviewers to the legal guardians of the study participants. Data were obtained regarding general characteristics of recurrent wheezing; general sociodemographic, environmental, and biologic factors; and atopy-related factors. The magnitude of the statistical association was assessed by calculating ORs and their corresponding 95% CIs by using multiple logistic regression. Results: We included 124 children in the study. The prevalence of vitamin D defi ciency/insuffi ciency in the sample was 57.3%. Vitamin D deficiency/insufficiency was found to be associated with wheezing in the fi rst year of life, personal history of atopic dermatitis, environmental pollution, and vitamin D supplementation until 2 years of age. Conclusions: The prevalence of vitamin D defi ciency/insuffi ciency was high in our sample. Vitamin D concentrations were directly associated with vitamin D supplementation until 2 years of age and were inversely associated with wheezing events in the fi rst year of life, personal history of atopic dermatitis, and environmental pollution.