| spelling |
2023-03-01T15:28:12Z2023-03-01T15:28:12Z20177210110610.17058/reci.v7i2.830222383360http://hdl.handle.net/1843/50563Justificativa e Objetivos: Nas instituições hospitalares, as unidades de terapia intensiva são consideradas o epicentro de resistência bacteriana em razão da maior ocorrência de surtos por bactérias multirresistentes. A monitorização do perfil microbiológico dos micror- ganismos associados a infecções é fundamental para apoiar o uso racional de antimicrobianos e as medidas de prevenção e controle de infecções. O objetivo desse estudo foi verificar o perfil de sensibilidade de microrganismos aos antimicrobianos associados à ocorrência de colonização e infecções em uma unidade de terapia intensiva. Métodos: Tratou-se de uma coorte com seguimento de 2.137 pacientes (2005 – 2008) de um hospital universitário de Belo Horizonte. Resultados: Foram realizadas 426 (19,9%) culturas microbiológicas, sendo que 61,7% (263) se referiam a colonização por microrganismos resistentes, destacando-se 39%Acinetobacter baumanni (resistentes aos carbapenêmicos), 21% Pseudomonas aeruginosa (resistentes aos carbapenêmicos) e 14% Staphylococcus aureus (resistentes à oxacilina), seguidos de Klebsiella pneumoniae e Escherichia coli; 282 pacientes foram diagnosticados com infecções hospitalares (13,2%), sendo 86 associadas a microrganismos resistentes. Conclusões: Concluiu-se que o perfil dos microrganismos associados a colonização ou infecção de pacientes na unidade de terapia intensiva entre 2005 e 2008 foi similar ao observado em outros estudos no Brasil e América Latina, com predominância dos bastonetes Gram negativos. Evidenciou-se a necessidade de monitoramento das condições ambientais, de limpeza e sazonais, como variação de temperatura e umidade, que podem favorecer a replicação de microrganismos, como parte das medidas de controle da disseminação.Background and Objectives: Intensive care units are considered the main focus of bacterial resistance in hospital settings because they are the place where most multiresistant bacterial outbreaks take place. Monitoring the microbiological profile of organisms that cause infections is fundamental to support the rational use of antimicrobial agents and implement infection prevention and control measures. The objective of the present study was to assess the profile of sensitivity of microorganisms associated with colonization and infection to antimicrobial agents in an intensive care unit. Methods: The investigation was a cohort study with 2,137 patients admitted to a teaching hospital in Belo Horizonte from 2005 to 2008. Results: A total of 426 (19.9%) microbiological cultures were prepared, and around half this number (263 or 61.7%) were related to colonization by resistant microorganisms. The predominant microorganisms were Acinetobacter baumanni (39%), Pseudomonas aeruginosa (21%) (both resistant to carbapenem antibiotics), Staphylococcus aureus (14%) (resistant to oxa-cillin), followed by Klebsiella pneumoniae and Escherichia coli. Two hundred and eighty-two patients (13.2%) were diagnosed with hospitalinfections, with 86 caused by resistant microorganisms. Conclusions: The profile of microorganisms associated with colonization and infection in the studied intensive care unit was similar to that reported in other studies in Brazil and Latin America, with predominance of Gram negative bacilli. The investigation stressed the need to monitor environmental, cleaning and seasonal conditions, such as variations in temperature and humidity, that may favor the reproduction of microorganisms, as one of the infection control measuresporUniversidade Federal de Minas GeraisUFMGBrasilENF - DEPARTAMENTO DE ENFERMAGEM BÁSICAFCE - DEPARTAMENTO DE CIÊNCIAS ADMINISTRATIVASInfecção hospitalarHospitaisMicrobiologia médicaInfecção hospitalarFarmacorresistência bacterianaUnidades de terapia intensivaPerfil dos microrganismos associados à colonização e infecção em terapia intensivaProfile of microorganisms associated with colonization and infection in intensive therapyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articledoi:10.17058/reci.v7i2.8302Adriana Cristina OliveiraAdriana Oliveira de PaulaRobert Iquiapaza,Camila Sarmento Gamainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/50563/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALPerfil dos microrganismos associados à colonização e infecção em terapia intensiva.pdfPerfil dos microrganismos associados à colonização e infecção em terapia intensiva.pdfapplication/pdf890323https://repositorio.ufmg.br/bitstream/1843/50563/2/Perfil%20dos%20microrganismos%20associados%20%c3%a0%20coloniza%c3%a7%c3%a3o%20e%20infec%c3%a7%c3%a3o%20em%20terapia%20intensiva.pdfd0b8b6cc53b8bd950b7d87fbb22dcd9fMD521843/505632023-03-01 12:28:12.953oai:repositorio.ufmg.br:1843/50563TElDRU7vv71BIERFIERJU1RSSUJVSe+/ve+/vU8gTu+/vU8tRVhDTFVTSVZBIERPIFJFUE9TSVTvv71SSU8gSU5TVElUVUNJT05BTCBEQSBVRk1HCiAKCkNvbSBhIGFwcmVzZW50Ye+/ve+/vW8gZGVzdGEgbGljZW7vv71hLCB2b2Pvv70gKG8gYXV0b3IgKGVzKSBvdSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGRlIGF1dG9yKSBjb25jZWRlIGFvIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRk1HIChSSS1VRk1HKSBvIGRpcmVpdG8gbu+/vW8gZXhjbHVzaXZvIGUgaXJyZXZvZ++/vXZlbCBkZSByZXByb2R1emlyIGUvb3UgZGlzdHJpYnVpciBhIHN1YSBwdWJsaWNh77+977+9byAoaW5jbHVpbmRvIG8gcmVzdW1vKSBwb3IgdG9kbyBvIG11bmRvIG5vIGZvcm1hdG8gaW1wcmVzc28gZSBlbGV0cu+/vW5pY28gZSBlbSBxdWFscXVlciBtZWlvLCBpbmNsdWluZG8gb3MgZm9ybWF0b3Mg77+9dWRpbyBvdSB277+9ZGVvLgoKVm9j77+9IGRlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zvv710aWNhIGRlIGNvcHlyaWdodCBkYSBlZGl0b3JhIGRvIHNldSBkb2N1bWVudG8gZSBxdWUgY29uaGVjZSBlIGFjZWl0YSBhcyBEaXJldHJpemVzIGRvIFJJLVVGTUcuCgpWb2Pvv70gY29uY29yZGEgcXVlIG8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVGTUcgcG9kZSwgc2VtIGFsdGVyYXIgbyBjb250Ze+/vWRvLCB0cmFuc3BvciBhIHN1YSBwdWJsaWNh77+977+9byBwYXJhIHF1YWxxdWVyIG1laW8gb3UgZm9ybWF0byBwYXJhIGZpbnMgZGUgcHJlc2VydmHvv73vv71vLgoKVm9j77+9IHRhbWLvv71tIGNvbmNvcmRhIHF1ZSBvIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRk1HIHBvZGUgbWFudGVyIG1haXMgZGUgdW1hIGPvv71waWEgZGUgc3VhIHB1YmxpY2Hvv73vv71vIHBhcmEgZmlucyBkZSBzZWd1cmFu77+9YSwgYmFjay11cCBlIHByZXNlcnZh77+977+9by4KClZvY++/vSBkZWNsYXJhIHF1ZSBhIHN1YSBwdWJsaWNh77+977+9byDvv70gb3JpZ2luYWwgZSBxdWUgdm9j77+9IHRlbSBvIHBvZGVyIGRlIGNvbmNlZGVyIG9zIGRpcmVpdG9zIGNvbnRpZG9zIG5lc3RhIGxpY2Vu77+9YS4gVm9j77+9IHRhbWLvv71tIGRlY2xhcmEgcXVlIG8gZGVw77+9c2l0byBkZSBzdWEgcHVibGljYe+/ve+/vW8gbu+/vW8sIHF1ZSBzZWphIGRlIHNldSBjb25oZWNpbWVudG8sIGluZnJpbmdlIGRpcmVpdG9zIGF1dG9yYWlzIGRlIG5pbmd177+9bS4KCkNhc28gYSBzdWEgcHVibGljYe+/ve+/vW8gY29udGVuaGEgbWF0ZXJpYWwgcXVlIHZvY++/vSBu77+9byBwb3NzdWkgYSB0aXR1bGFyaWRhZGUgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCB2b2Pvv70gZGVjbGFyYSBxdWUgb2J0ZXZlIGEgcGVybWlzc++/vW8gaXJyZXN0cml0YSBkbyBkZXRlbnRvciBkb3MgZGlyZWl0b3MgYXV0b3JhaXMgcGFyYSBjb25jZWRlciBhbyBSZXBvc2l077+9cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZNRyBvcyBkaXJlaXRvcyBhcHJlc2VudGFkb3MgbmVzdGEgbGljZW7vv71hLCBlIHF1ZSBlc3NlIG1hdGVyaWFsIGRlIHByb3ByaWVkYWRlIGRlIHRlcmNlaXJvcyBlc3Tvv70gY2xhcmFtZW50ZSBpZGVudGlmaWNhZG8gZSByZWNvbmhlY2lkbyBubyB0ZXh0byBvdSBubyBjb250Ze+/vWRvIGRhIHB1YmxpY2Hvv73vv71vIG9yYSBkZXBvc2l0YWRhLgoKQ0FTTyBBIFBVQkxJQ0Hvv73vv71PIE9SQSBERVBPU0lUQURBIFRFTkhBIFNJRE8gUkVTVUxUQURPIERFIFVNIFBBVFJPQ++/vU5JTyBPVSBBUE9JTyBERSBVTUEgQUfvv71OQ0lBIERFIEZPTUVOVE8gT1UgT1VUUk8gT1JHQU5JU01PLCBWT0Pvv70gREVDTEFSQSBRVUUgUkVTUEVJVE9VIFRPRE9TIEUgUVVBSVNRVUVSIERJUkVJVE9TIERFIFJFVklT77+9TyBDT01PIFRBTULvv71NIEFTIERFTUFJUyBPQlJJR0Hvv73vv71FUyBFWElHSURBUyBQT1IgQ09OVFJBVE8gT1UgQUNPUkRPLgoKTyBSZXBvc2l077+9cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZNRyBzZSBjb21wcm9tZXRlIGEgaWRlbnRpZmljYXIgY2xhcmFtZW50ZSBvIHNldSBub21lKHMpIG91IG8ocykgbm9tZXMocykgZG8ocykgZGV0ZW50b3IoZXMpIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyBkYSBwdWJsaWNh77+977+9bywgZSBu77+9byBmYXLvv70gcXVhbHF1ZXIgYWx0ZXJh77+977+9bywgYWzvv71tIGRhcXVlbGFzIGNvbmNlZGlkYXMgcG9yIGVzdGEgbGljZW7vv71hLgo=Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-03-01T15:28:12Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
|