Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil

Detalhes bibliográficos
Autor(a) principal: Romulo Estevam Ribeiro Pedro
Data de Publicação: 2019
Outros Autores: Moisés Felix de Carvalho Neto, Alves Chagas Edvan, Pollyana C. Chagas, Jacqueline Aparecida Takahashi, Ana Cristina G. Reis de Melo, Ricardo Carvalho Dos Santos, Antonio A. de Melo Filho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.3303/CET1975061
http://hdl.handle.net/1843/59572
https://orcid.org/0000-0002-8831-1609
Resumo: CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
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spelling 2023-10-17T23:30:41Z2023-10-17T23:30:41Z201975361366https://doi.org/10.3303/CET19750612283-9216http://hdl.handle.net/1843/59572https://orcid.org/0000-0002-8831-1609CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e ProjetosOne of the oldest plants known and considered a symbol of wisdom in antiquity especially in China is cinnamon (Cinnamomum zeylanicum Nees). The objective of this work was to study the fixed oil extracted from cinnamon (Cinnamomum zeylanicum Nees) seeds regarding its biological potential for inhibition of acetylcholinesterase. The inhibitory activity test of hexane extract studied on the enzyme acetylcholinesterase was conducted based on Ellman spectrophotometric method. The percentage of acetylcholinesterase enzyme inhibition was 65.5%, being considered a potent inhibitor according to the literature standarts. In conclusion, the results indicate that the oil can be used in the pharmaceutical industry as part or to develop drugs for treatment of certain neurodegenerative diseases, such as Alzheimer's disease.engUniversidade Federal de Minas GeraisUFMGBrasilICX - DEPARTAMENTO DE QUÍMICAChemical Engineering TransactionsAlzheimer, Doença deProdutos NaturaisFixed oilBiological activityNeurodegenerative diseasesAlzheimerNatural productsAcetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.aidic.it/cet/19/75/061.pdfRomulo Estevam Ribeiro PedroMoisés Felix de Carvalho NetoAlves Chagas EdvanPollyana C. ChagasJacqueline Aparecida TakahashiAna Cristina G. Reis de MeloRicardo Carvalho Dos SantosAntonio A. de Melo Filhoapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/59572/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALAcetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil.pdfAcetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil.pdfapplication/pdf1546046https://repositorio.ufmg.br/bitstream/1843/59572/2/Acetylcholinesterase%20Inhibitory%20Potential%20in%20Cinnamon%20Seed%20%20Oil%20%28Cinnamomum%20zeylanicum%20Nees%29%20Lauraceae%20from%20%20Roraima%2c%20Brazil.pdf77dd92057a84ca92d18e3f4971be8d39MD521843/595722023-10-17 20:30:41.465oai:repositorio.ufmg.br:1843/59572TElDRU7vv71BIERFIERJU1RSSUJVSe+/ve+/vU8gTu+/vU8tRVhDTFVTSVZBIERPIFJFUE9TSVTvv71SSU8gSU5TVElUVUNJT05BTCBEQSBVRk1HCiAKCkNvbSBhIGFwcmVzZW50Ye+/ve+/vW8gZGVzdGEgbGljZW7vv71hLCB2b2Pvv70gKG8gYXV0b3IgKGVzKSBvdSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGRlIGF1dG9yKSBjb25jZWRlIGFvIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRk1HIChSSS1VRk1HKSBvIGRpcmVpdG8gbu+/vW8gZXhjbHVzaXZvIGUgaXJyZXZvZ++/vXZlbCBkZSByZXByb2R1emlyIGUvb3UgZGlzdHJpYnVpciBhIHN1YSBwdWJsaWNh77+977+9byAoaW5jbHVpbmRvIG8gcmVzdW1vKSBwb3IgdG9kbyBvIG11bmRvIG5vIGZvcm1hdG8gaW1wcmVzc28gZSBlbGV0cu+/vW5pY28gZSBlbSBxdWFscXVlciBtZWlvLCBpbmNsdWluZG8gb3MgZm9ybWF0b3Mg77+9dWRpbyBvdSB277+9ZGVvLgoKVm9j77+9IGRlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zvv710aWNhIGRlIGNvcHlyaWdodCBkYSBlZGl0b3JhIGRvIHNldSBkb2N1bWVudG8gZSBxdWUgY29uaGVjZSBlIGFjZWl0YSBhcyBEaXJldHJpemVzIGRvIFJJLVVGTUcuCgpWb2Pvv70gY29uY29yZGEgcXVlIG8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVGTUcgcG9kZSwgc2VtIGFsdGVyYXIgbyBjb250Ze+/vWRvLCB0cmFuc3BvciBhIHN1YSBwdWJsaWNh77+977+9byBwYXJhIHF1YWxxdWVyIG1laW8gb3UgZm9ybWF0byBwYXJhIGZpbnMgZGUgcHJlc2VydmHvv73vv71vLgoKVm9j77+9IHRhbWLvv71tIGNvbmNvcmRhIHF1ZSBvIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRk1HIHBvZGUgbWFudGVyIG1haXMgZGUgdW1hIGPvv71waWEgZGUgc3VhIHB1YmxpY2Hvv73vv71vIHBhcmEgZmlucyBkZSBzZWd1cmFu77+9YSwgYmFjay11cCBlIHByZXNlcnZh77+977+9by4KClZvY++/vSBkZWNsYXJhIHF1ZSBhIHN1YSBwdWJsaWNh77+977+9byDvv70gb3JpZ2luYWwgZSBxdWUgdm9j77+9IHRlbSBvIHBvZGVyIGRlIGNvbmNlZGVyIG9zIGRpcmVpdG9zIGNvbnRpZG9zIG5lc3RhIGxpY2Vu77+9YS4gVm9j77+9IHRhbWLvv71tIGRlY2xhcmEgcXVlIG8gZGVw77+9c2l0byBkZSBzdWEgcHVibGljYe+/ve+/vW8gbu+/vW8sIHF1ZSBzZWphIGRlIHNldSBjb25oZWNpbWVudG8sIGluZnJpbmdlIGRpcmVpdG9zIGF1dG9yYWlzIGRlIG5pbmd177+9bS4KCkNhc28gYSBzdWEgcHVibGljYe+/ve+/vW8gY29udGVuaGEgbWF0ZXJpYWwgcXVlIHZvY++/vSBu77+9byBwb3NzdWkgYSB0aXR1bGFyaWRhZGUgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCB2b2Pvv70gZGVjbGFyYSBxdWUgb2J0ZXZlIGEgcGVybWlzc++/vW8gaXJyZXN0cml0YSBkbyBkZXRlbnRvciBkb3MgZGlyZWl0b3MgYXV0b3JhaXMgcGFyYSBjb25jZWRlciBhbyBSZXBvc2l077+9cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZNRyBvcyBkaXJlaXRvcyBhcHJlc2VudGFkb3MgbmVzdGEgbGljZW7vv71hLCBlIHF1ZSBlc3NlIG1hdGVyaWFsIGRlIHByb3ByaWVkYWRlIGRlIHRlcmNlaXJvcyBlc3Tvv70gY2xhcmFtZW50ZSBpZGVudGlmaWNhZG8gZSByZWNvbmhlY2lkbyBubyB0ZXh0byBvdSBubyBjb250Ze+/vWRvIGRhIHB1YmxpY2Hvv73vv71vIG9yYSBkZXBvc2l0YWRhLgoKQ0FTTyBBIFBVQkxJQ0Hvv73vv71PIE9SQSBERVBPU0lUQURBIFRFTkhBIFNJRE8gUkVTVUxUQURPIERFIFVNIFBBVFJPQ++/vU5JTyBPVSBBUE9JTyBERSBVTUEgQUfvv71OQ0lBIERFIEZPTUVOVE8gT1UgT1VUUk8gT1JHQU5JU01PLCBWT0Pvv70gREVDTEFSQSBRVUUgUkVTUEVJVE9VIFRPRE9TIEUgUVVBSVNRVUVSIERJUkVJVE9TIERFIFJFVklT77+9TyBDT01PIFRBTULvv71NIEFTIERFTUFJUyBPQlJJR0Hvv73vv71FUyBFWElHSURBUyBQT1IgQ09OVFJBVE8gT1UgQUNPUkRPLgoKTyBSZXBvc2l077+9cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZNRyBzZSBjb21wcm9tZXRlIGEgaWRlbnRpZmljYXIgY2xhcmFtZW50ZSBvIHNldSBub21lKHMpIG91IG8ocykgbm9tZXMocykgZG8ocykgZGV0ZW50b3IoZXMpIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyBkYSBwdWJsaWNh77+977+9bywgZSBu77+9byBmYXLvv70gcXVhbHF1ZXIgYWx0ZXJh77+977+9bywgYWzvv71tIGRhcXVlbGFzIGNvbmNlZGlkYXMgcG9yIGVzdGEgbGljZW7vv71hLgo=Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-10-17T23:30:41Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
title Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
spellingShingle Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
Romulo Estevam Ribeiro Pedro
Fixed oil
Biological activity
Neurodegenerative diseases
Alzheimer
Natural products
Alzheimer, Doença de
Produtos Naturais
title_short Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
title_full Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
title_fullStr Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
title_full_unstemmed Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
title_sort Acetylcholinesterase Inhibitory Potential in Cinnamon Seed Oil (Cinnamomum zeylanicum Nees) Lauraceae from Roraima, Brazil
author Romulo Estevam Ribeiro Pedro
author_facet Romulo Estevam Ribeiro Pedro
Moisés Felix de Carvalho Neto
Alves Chagas Edvan
Pollyana C. Chagas
Jacqueline Aparecida Takahashi
Ana Cristina G. Reis de Melo
Ricardo Carvalho Dos Santos
Antonio A. de Melo Filho
author_role author
author2 Moisés Felix de Carvalho Neto
Alves Chagas Edvan
Pollyana C. Chagas
Jacqueline Aparecida Takahashi
Ana Cristina G. Reis de Melo
Ricardo Carvalho Dos Santos
Antonio A. de Melo Filho
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Romulo Estevam Ribeiro Pedro
Moisés Felix de Carvalho Neto
Alves Chagas Edvan
Pollyana C. Chagas
Jacqueline Aparecida Takahashi
Ana Cristina G. Reis de Melo
Ricardo Carvalho Dos Santos
Antonio A. de Melo Filho
dc.subject.por.fl_str_mv Fixed oil
Biological activity
Neurodegenerative diseases
Alzheimer
Natural products
topic Fixed oil
Biological activity
Neurodegenerative diseases
Alzheimer
Natural products
Alzheimer, Doença de
Produtos Naturais
dc.subject.other.pt_BR.fl_str_mv Alzheimer, Doença de
Produtos Naturais
description CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
publishDate 2019
dc.date.issued.fl_str_mv 2019
dc.date.accessioned.fl_str_mv 2023-10-17T23:30:41Z
dc.date.available.fl_str_mv 2023-10-17T23:30:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/59572
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.3303/CET1975061
dc.identifier.issn.pt_BR.fl_str_mv 2283-9216
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0002-8831-1609
url https://doi.org/10.3303/CET1975061
http://hdl.handle.net/1843/59572
https://orcid.org/0000-0002-8831-1609
identifier_str_mv 2283-9216
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Chemical Engineering Transactions
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv ICX - DEPARTAMENTO DE QUÍMICA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
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