Recommendations by the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and the Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) on vaccination in general and specifically against SARS-CoV-2 for patients with demyelinating diseases of the central nervous system

• Main Author: Jefferson Becker
• Publication Date: 2021
• Other Authors: Lis Campos Ferreira, Alfredo Damasceno, Denis Bernardi Bichuetti, Paulo Pereira Christo, Dagoberto Callegaro, Marco Aurélio Lana Peixoto, Nise Alessandra de Carvalho Sousa, Sérgio Monteiro de Almeida, Tarso Adoni, Juliana Machado Santiago dos Santos Amaral, Thiago de Faria Junqueira, Samira Luisa Apóstolos Pereira, Ana Beatriz Ayroza Galvão Ribeiro Gomes, Milena Sales Pitombeira, Renata Barbosa Paolilo, Anderson Kuntz Grzesiuk, Ana Claudia Piccolo, José Arthur Costa D´Almeida, Antônio Pereira Gomes Neto, Augusto César Penalva de Oliveira, Bianca Etelvina Santos de Oliveira, Carlos Bernardo Tauil, Claudia Cristina Ferreira Vasconcelos, Damacio Ramón Kaimen Maciel, Daniel Lima Varela, Denise Sisterolli Diniz, Enedina Maria Lobato de Oliveira, Fabiola Rachid Malfetano, Fernando Elias Borges, Fernando Faria Andrade Figueira, Francisco de Assis Aquino Gondim, Giordani Rodrigues dos Passos, Guilherme Diogo Silva, Guilherme Sciascia do Olival, Gutemberg Augusto Cruz dos Santos, Heloisa Helena Ruocco, Henry Koiti Sato, Herval Ribeiro Soares Neto, Leandro Cortoni Calia, Marcus Vinícius Magno Gonçalves, Maria Cecilia Aragón de Vecino, Maria Lucia Vellutini Pimentel, Marlise de Castro Ribeiro, Mateus Boaventura de Oliveira, Mônica Koncke Fiuza Parolin, Renata Brant de Souza Melo, Robson Lázaro, Rodrigo Barbosa Thomaz, Rodrigo Gonçalves Kleinpaul Vieira, Ronaldo Maciel Dias, Sidney Gomes, Simone Abrante Lucatto, Soniza Vieira Alves Leon, Thiago Fukuda, Taysa Alexandrino Gonsalves Jubé Ribeiro, Thereza Cristina D’ávila Winckler, Yara Dadalti Fragoso, Osvaldo José Moreira do Nascimento, Maria Lucia Brito Ferreira, Maria Fernanda Mendes, Doralina Guimarães Brum Souza, Felipe von Glehn da Silva
• Format: Article
• Language: eng
• Source: Repositório Institucional da UFMG
• Download full: https://doi.org/10.1590/0004-282X-ANP-2021-0162; http://hdl.handle.net/1843/55209; https://orcid.org/0000-0002-9981-3620; https://orcid.org/0000-0002-4456-2684; https://orcid.org/0000-0002-7919-3989; https://orcid.org/0000-0002-4011-3734; https://orcid.org/0000-0003-1224-5243; https://orcid.org/0000-0003-0077-173X; https://orcid.org/0000-0003-2454-681X; https://orcid.org/0000-0003-3185-2903; https://orcid.org/0000-0001-5690-105X; https://orcid.org/0000-0002-5008-2783; https://orcid.org/0000-0003-1615-8008; https://orcid.org/0000-0002-5679-1759; https://orcid.org/0000-0003-3493-1199; https://orcid.org/0000-0003-1657-6891; https://orcid.org/0000-0002-3298-0264; https://orcid.org/0000-0003-3548-8467; https://orcid.org/0000-0002-7480-6782; https://orcid.org/0000-0003-0834-1056; https://orcid.org/0000-0002-6627-6515; https://orcid.org/0000-0002-0755-9478; https://orcid.org/0000-0002-4084-7973; https://orcid.org/0000-0001-7484-3586; https://orcid.org/0000-0003-1137-2398; https://orcid.org/0000-0003-0833-4024; https://orcid.org/0000-0002-8699-0636; https://orcid.org/0000-0002-3043-1640; https://orcid.org/0000-0002-3078-6804; https://orcid.org/0000-0002-4939-7200; https://orcid.org/0000-0002-8275-3801; https://orcid.org/0000-0001-7668-0434; https://orcid.org/0000-0003-3242-9007; https://orcid.org/0000-0002-8957-5796; https://orcid.org/0000-0002-8949-6115; https://orcid.org/0000-0001-9764-3763; https://orcid.org/0000-0002-2717-7522; https://orcid.org/0000-0002-7333-1420; https://orcid.org/0000-0001-5394-648X; https://orcid.org/0000-0002-5582-1792; https://orcid.org/0000-0002-1694-0457; https://orcid.org/0000-0002-5758-5789; https://orcid.org/0000-0002-9127-7886; https://orcid.org/0000-0001-9393-6999; https://orcid.org/0000-0003-3515-4061; https://orcid.org/0000-0002-4402-099X; https://orcid.org/0000-0002-5914-8099; https://orcid.org/0000-0003-2171-8241; https://orcid.org/0000-0002-6267-2940; https://orcid.org/0000-0001-7537-5729; https://orcid.org/0000-0002-9287-6864; https://orcid.org/0000-0001-5750-6828; https://orcid.org/0000-0003-3987-9596; https://orcid.org/0000-0002-9744-5916; https://orcid.org/0000-0002-8856-0007; https://orcid.org/0000-0002-1538-6730; https://orcid.org/0000-0002-7718-4288; https://orcid.org/0000-0001-8202-8856; https://orcid.org/0000-0003-1438-2583; https://orcid.org/0000-0001-8726-089X; https://orcid.org/0000-0003-3516-485X; https://orcid.org/0000-0002-6136-4612; https://orcid.org/0000-0003-3983-6019; https://orcid.org/0000-0002-9050-3319; https://orcid.org/0000-0002-1004-7641
• topic: Demyelinating autoimmune diseases, CNS; Multiple sclerosis; Neuromyelitis optica; Vaccination; COVID-19; SARS-CoV-2; COVID-19 (Doença); SARS-CoV-2; Doenças autoimunes desmielinizantes do sistema nervoso central; Esclerose múltipla; Neuromielite óptica; Vacinação

The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize the seriousness of the current situation in view of the spread of COVID-19 in our country. Therefore, reference guides on vaccination for clinicians, patients, and public health authorities are particularly important to prevent some infectious diseases. The DCNI/ABN and BCTRIMS recommend that patients with CNS demyelinating diseases (e.g., MS and NMOSD) be continually monitored for updates to their vaccination schedule, especially at the beginning or before a change in treatment with a disease modifying drug (DMD). It is also important to note that vaccines are safe, and physicians should encourage their use in all patients. Clearly, special care should be taken when live attenuated viruses are involved. Finally, it is important for physicians to verify which DMD the patient is receiving and when the last dose was taken, as each drug may affect the induction of immune response differently.