Reply to Gómez Marín

• Autor(a) principal: Ana Carolina Aguiar Vasconceloscarneiro
• Data de Publicação: 2016
• Outros Autores: Andréa Teixeira-carvalho, Ricardo Wagner Almeida Vitor, Olindo Assis Martins Filho, Anderson da Silva Machado, Samantha Ribeiro Béla, Julia Gatti Ladeia Costa, Gláucia Manzan Queiroz Andrade, Daniel Vitor Vasconcelos-santos, José Nélio Januário, Jordana Grazziela Coelho-dos-reis, Eloisa Amália Vieira Ferro
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: http://hdl.handle.net/1843/55289; https://orcid.org/0000-0002-0912-3782
• topic: Toxoplasmosis; Children; Toxoplasma gondii; Toxoplasmose; Crianças; Toxoplasma

TO THE EDITOR—We thank Gómez Marín for the comments. Regarding the question raised, our study was part of a population-based investigation on neonatal screening for toxoplasmosis, with a lack of prenatal treatment being the rule. Blood samples were collected when newborns were brought for confirmatory serologic testing [1] and before initiation of postnatal treatment. Our results prompted local authorities to establish a prenatalscreening program for congenital toxoplasmosis in our state, to provide prenatal treatment and possibly decrease the burden of the disease. Analysis of the immune response of these children after 1 year of postnatal treatment is nearly completed, and we are curious to know whether and how antiparasitic drugs may have affected immune responses to Toxoplasma gondii in these individuals. These results, when available, will hopefully shed further light into the immunopathogenesis and optimal immunomodulation of this infection. Notes Financial support. This work was supported by the Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG), the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), the Secretaria de Saúde de Minas Gerais, and the Núcleo de Ações e Pesquisa em Apoio Diagnóstico (NUPAD). Potential conflicts of interest. All authors: No reported conflicts. All authors have submitted nthe ICMJE Form for Disclosure of Potential Con flicts of Interest. Conflicts that the editors consid er relevant to the content of the manuscript have been disclosed.