Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFMG |
| Texto Completo: | https://doi.org/10.3390/toxins14040251 http://hdl.handle.net/1843/60195 https://orcid.org/0000-0003-3725-2482 https://orcid.org/0000-0001-9018-4998 https://orcid.org/0000-0002-0190-0209 https://orcid.org/0000-0003-1484-9817 https://orcid.org/0000-0002-2524-8534 https://orcid.org/0000-0001-8584-1690 |
Resumo: | FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais |
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2023-10-27T21:07:54Z2023-10-27T21:07:54Z2022144https://doi.org/10.3390/toxins140402512072-6651http://hdl.handle.net/1843/60195https://orcid.org/0000-0003-3725-2482https://orcid.org/0000-0001-9018-4998https://orcid.org/0000-0002-0190-0209https://orcid.org/0000-0003-1484-9817https://orcid.org/0000-0002-2524-8534https://orcid.org/0000-0001-8584-1690FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisThe neurotoxic alkaloid β-N-methyl-amino-l-alanine (BMAA) and related isomers, including N-(2-aminoethyl glycine) (AEG), β-amino-N-methyl alanine (BAMA), and 2,4-diaminobutyric acid (DAB), have been reported previously in cyanobacterial samples. However, there are conflicting reports regarding their occurrence in surface waters. In this study, we evaluated the impact of amending lake water samples with trichloroacetic acid (0.1 M TCA) on the detection of BMAA isomers, compared with pre-existing protocols. A sensitive instrumental method was enlisted for the survey, with limits of detection in the range of 5–10 ng L−1. Higher detection rates and significantly greater levels (paired Wilcoxon’s signed-rank tests, p < 0.001) of BMAA isomers were observed in TCA-amended samples (method B) compared to samples without TCA (method A). The overall range of B/A ratios was 0.67–8.25 for AEG (up to +725%) and 0.69–15.5 for DAB (up to +1450%), with absolute concentration increases in TCA-amended samples of up to +15,000 ng L−1 for AEG and +650 ng L−1 for DAB. We also documented the trends in the occurrence of BMAA isomers for a large breadth of field-collected lakes from Brazil, Canada, France, Mexico, and the United Kingdom. Data gathered during this overarching campaign (overall, n = 390 within 45 lake sampling sites) indicated frequent detections of AEG and DAB isomers, with detection rates of 30% and 43% and maximum levels of 19,000 ng L−1 and 1100 ng L−1, respectively. In contrast, BAMA was found in less than 8% of the water samples, and BMAA was not found in any sample. These results support the analyses of free-living cyanobacteria, wherein BMAA was often reported at concentrations of 2–4 orders of magnitude lower than AEG and DAB. Seasonal measurements conducted at two bloom-impacted lakes indicated limited correlations of BMAA isomers with total microcystins or chlorophyll-a, which deserves further investigation.engUniversidade Federal de Minas GeraisUFMGBrasilICB - DEPARTAMENTO DE BOTÂNICAToxinsLagosCianobactériasToxinas de cianobactériasLake waterβ-N-methyl-amino-l-alanine (BMAA)2,4-diaminobutyric acid (DAB)N-(2- aminoethyl) glycine (AEG)Trichloroacetic acid (TCA)Temporal trendsOccurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United KingdomOcorrência de isômeros BMAA em lagos e reservatórios afetados pelo florescimento do Brasil, Canadá, França, México e Reino Unidoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.mdpi.com/2072-6651/14/4/251Safa AbbesSung Vo DuyGabriel MunozQuoc Tuc DinhDana F. SimonBarry HuskHelen M. BaulchBrigitte Vinçon-LeiteNathalie FortinCharles W. GreerMegan L. LarsenJason J. VenkiteswaranFelipe Fernando Martínez JerónimoAlessandra GianiChris D. LoweNicolas TromasSébastien Sauvéapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/60195/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALOccurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom.pdfOccurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom.pdfapplication/pdf7485758https://repositorio.ufmg.br/bitstream/1843/60195/2/Occurrence%20of%20BMAA%20isomers%20in%20bloom-impacted%20lakes%20and%20reservoirs%20of%20Brazil%2c%20Canada%2c%20France%2c%20Mexico%2c%20and%20the%20United%20Kingdom.pdf9d58cfd43f879b75dd1b0114d185e6fcMD521843/601952023-10-27 18:07:54.328oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-10-27T21:07:54Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.pt_BR.fl_str_mv |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| dc.title.alternative.pt_BR.fl_str_mv |
Ocorrência de isômeros BMAA em lagos e reservatórios afetados pelo florescimento do Brasil, Canadá, França, México e Reino Unido |
| title |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| spellingShingle |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom Safa Abbes Lake water β-N-methyl-amino-l-alanine (BMAA) 2,4-diaminobutyric acid (DAB) N-(2- aminoethyl) glycine (AEG) Trichloroacetic acid (TCA) Temporal trends Lagos Cianobactérias Toxinas de cianobactérias |
| title_short |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| title_full |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| title_fullStr |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| title_full_unstemmed |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| title_sort |
Occurrence of BMAA isomers in bloom-impacted lakes and reservoirs of Brazil, Canada, France, Mexico, and the United Kingdom |
| author |
Safa Abbes |
| author_facet |
Safa Abbes Sung Vo Duy Gabriel Munoz Quoc Tuc Dinh Dana F. Simon Barry Husk Helen M. Baulch Brigitte Vinçon-Leite Nathalie Fortin Charles W. Greer Megan L. Larsen Jason J. Venkiteswaran Felipe Fernando Martínez Jerónimo Alessandra Giani Chris D. Lowe Nicolas Tromas Sébastien Sauvé |
| author_role |
author |
| author2 |
Sung Vo Duy Gabriel Munoz Quoc Tuc Dinh Dana F. Simon Barry Husk Helen M. Baulch Brigitte Vinçon-Leite Nathalie Fortin Charles W. Greer Megan L. Larsen Jason J. Venkiteswaran Felipe Fernando Martínez Jerónimo Alessandra Giani Chris D. Lowe Nicolas Tromas Sébastien Sauvé |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Safa Abbes Sung Vo Duy Gabriel Munoz Quoc Tuc Dinh Dana F. Simon Barry Husk Helen M. Baulch Brigitte Vinçon-Leite Nathalie Fortin Charles W. Greer Megan L. Larsen Jason J. Venkiteswaran Felipe Fernando Martínez Jerónimo Alessandra Giani Chris D. Lowe Nicolas Tromas Sébastien Sauvé |
| dc.subject.por.fl_str_mv |
Lake water β-N-methyl-amino-l-alanine (BMAA) 2,4-diaminobutyric acid (DAB) N-(2- aminoethyl) glycine (AEG) Trichloroacetic acid (TCA) Temporal trends |
| topic |
Lake water β-N-methyl-amino-l-alanine (BMAA) 2,4-diaminobutyric acid (DAB) N-(2- aminoethyl) glycine (AEG) Trichloroacetic acid (TCA) Temporal trends Lagos Cianobactérias Toxinas de cianobactérias |
| dc.subject.other.pt_BR.fl_str_mv |
Lagos Cianobactérias Toxinas de cianobactérias |
| description |
FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais |
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2022 |
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2022 |
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2023-10-27T21:07:54Z |
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2023-10-27T21:07:54Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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http://hdl.handle.net/1843/60195 |
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https://doi.org/10.3390/toxins14040251 |
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2072-6651 |
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https://orcid.org/0000-0003-3725-2482 https://orcid.org/0000-0001-9018-4998 https://orcid.org/0000-0002-0190-0209 https://orcid.org/0000-0003-1484-9817 https://orcid.org/0000-0002-2524-8534 https://orcid.org/0000-0001-8584-1690 |
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https://doi.org/10.3390/toxins14040251 http://hdl.handle.net/1843/60195 https://orcid.org/0000-0003-3725-2482 https://orcid.org/0000-0001-9018-4998 https://orcid.org/0000-0002-0190-0209 https://orcid.org/0000-0003-1484-9817 https://orcid.org/0000-0002-2524-8534 https://orcid.org/0000-0001-8584-1690 |
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Toxins |
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Universidade Federal de Minas Gerais |
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ICB - DEPARTAMENTO DE BOTÂNICA |
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Universidade Federal de Minas Gerais |
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