Mortality predictors after liver transplant in the intensive care unit
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | https://doi.org/10.1016/j.transproceed.2018.02.087 http://hdl.handle.net/1843/48591 https://orcid.org/0000-0002-1165-2149 https://orcid.org/0000-0001-5363-0717 http://orcid.org/0000-0001-9989-4160 http://orcid.org/0000-0003-0949-5516 https://orcid.org/0000-0002-2920-2162 |
Resumo: | Background: The goal of this study was to evaluate the predictive factors of mortality in patients after liver transplantation in an intensive care unit from the University Hospital. Methods: This observational study was conducted by using a database analysis of University Hospital. The sample consisted of patients after liver transplantation registered in the database. The study variables of Sequential Organ Failure Assessment score, Acute Physiology and Chronic Health Disease Classification II (APACHE II), Model for End-Stage Liver Disease, and Child-Pugh scores, and the days of hospitalization in intensive care unit, mechanical ventilation time, and reintubation rate, were correlated. Statistical analysis was performed by using the χ2 test or Fisher exact test, the Mann-Whitney test, and logistic regression analysis. Results: Fifty-eight individuals were analyzed. In the death group, the days of hospitalization in the intensive care unit were within 12 ± 14 days, the time of mechanical ventilation was 180 ± 148 hours, the APACHE II value was 17.6 ± 7.3, the Sequential Organ Failure Assessment score was 8.2 ± 2.7, and reintubation was 40%. In the multivariate regression, the predictive indexes of mortality were the mortality given by APACHE II (odds ratio, 1.1; CI, 1.03–1.17; P = .004), mechanical ventilation time (odds ratio, 1.02; CI, 1.01–1.04; P = .001), and reintubation (odds ratio, 9.06; CI, 1.83–44.9; P = .007). An increase of 1 unit in APACHE II mortality increases the risk of death by 10.2%, and each hour of mechanical ventilation increases the risk of death by 2.6%. Conclusions: The time of mechanical ventilation, orotracheal reintubation, and the mortality given by APACHE II were the variables that best predicted death in this study. |
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2023-01-03T16:51:56Z2023-01-03T16:51:56Z2018-0650514241427https://doi.org/10.1016/j.transproceed.2018.02.0871873-2623http://hdl.handle.net/1843/48591https://orcid.org/0000-0002-1165-2149https://orcid.org/0000-0001-5363-0717http://orcid.org/0000-0001-9989-4160http://orcid.org/0000-0003-0949-5516https://orcid.org/0000-0002-2920-2162Background: The goal of this study was to evaluate the predictive factors of mortality in patients after liver transplantation in an intensive care unit from the University Hospital. Methods: This observational study was conducted by using a database analysis of University Hospital. The sample consisted of patients after liver transplantation registered in the database. The study variables of Sequential Organ Failure Assessment score, Acute Physiology and Chronic Health Disease Classification II (APACHE II), Model for End-Stage Liver Disease, and Child-Pugh scores, and the days of hospitalization in intensive care unit, mechanical ventilation time, and reintubation rate, were correlated. Statistical analysis was performed by using the χ2 test or Fisher exact test, the Mann-Whitney test, and logistic regression analysis. Results: Fifty-eight individuals were analyzed. In the death group, the days of hospitalization in the intensive care unit were within 12 ± 14 days, the time of mechanical ventilation was 180 ± 148 hours, the APACHE II value was 17.6 ± 7.3, the Sequential Organ Failure Assessment score was 8.2 ± 2.7, and reintubation was 40%. In the multivariate regression, the predictive indexes of mortality were the mortality given by APACHE II (odds ratio, 1.1; CI, 1.03–1.17; P = .004), mechanical ventilation time (odds ratio, 1.02; CI, 1.01–1.04; P = .001), and reintubation (odds ratio, 9.06; CI, 1.83–44.9; P = .007). An increase of 1 unit in APACHE II mortality increases the risk of death by 10.2%, and each hour of mechanical ventilation increases the risk of death by 2.6%. Conclusions: The time of mechanical ventilation, orotracheal reintubation, and the mortality given by APACHE II were the variables that best predicted death in this study.engUniversidade Federal de Minas GeraisUFMGBrasilEEF - DEPARTAMENTO DE FISIOTERAPIATransplantation ProceedingsTransplante de fígadoTransplante de fígado / mortalidadeUnidade de terapia intensivaMortality predictors after liver transplant in the intensive care unitinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.sciencedirect.com/science/article/pii/S0041134518302549?via%3DihubAna Paula Ragonete Dos Anjos AgostiniIlka de Fátima Santana Ferreira BoinRodrigo Marques TonellaAline Maria Heidemann SantosAntonio Luis Eiras FalcãoClaudinéia Muterle LogatoLígia dos Santos Roceto RattiLuciana Castilho de FigueiredoLuíz Cláudio Martinsapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/48591/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALMortality Predictors After Liver Transplant.pdfMortality Predictors After Liver Transplant.pdfapplication/pdf230858https://repositorio.ufmg.br/bitstream/1843/48591/2/Mortality%20Predictors%20After%20Liver%20Transplant.pdfd3272b8de0bbbd1b18cf6eb0a88e48d9MD521843/485912023-01-03 13:51:56.426oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-01-03T16:51:56Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.pt_BR.fl_str_mv |
Mortality predictors after liver transplant in the intensive care unit |
title |
Mortality predictors after liver transplant in the intensive care unit |
spellingShingle |
Mortality predictors after liver transplant in the intensive care unit Ana Paula Ragonete Dos Anjos Agostini Transplante de fígado Transplante de fígado / mortalidade Unidade de terapia intensiva |
title_short |
Mortality predictors after liver transplant in the intensive care unit |
title_full |
Mortality predictors after liver transplant in the intensive care unit |
title_fullStr |
Mortality predictors after liver transplant in the intensive care unit |
title_full_unstemmed |
Mortality predictors after liver transplant in the intensive care unit |
title_sort |
Mortality predictors after liver transplant in the intensive care unit |
author |
Ana Paula Ragonete Dos Anjos Agostini |
author_facet |
Ana Paula Ragonete Dos Anjos Agostini Ilka de Fátima Santana Ferreira Boin Rodrigo Marques Tonella Aline Maria Heidemann Santos Antonio Luis Eiras Falcão Claudinéia Muterle Logato Lígia dos Santos Roceto Ratti Luciana Castilho de Figueiredo Luíz Cláudio Martins |
author_role |
author |
author2 |
Ilka de Fátima Santana Ferreira Boin Rodrigo Marques Tonella Aline Maria Heidemann Santos Antonio Luis Eiras Falcão Claudinéia Muterle Logato Lígia dos Santos Roceto Ratti Luciana Castilho de Figueiredo Luíz Cláudio Martins |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Ana Paula Ragonete Dos Anjos Agostini Ilka de Fátima Santana Ferreira Boin Rodrigo Marques Tonella Aline Maria Heidemann Santos Antonio Luis Eiras Falcão Claudinéia Muterle Logato Lígia dos Santos Roceto Ratti Luciana Castilho de Figueiredo Luíz Cláudio Martins |
dc.subject.other.pt_BR.fl_str_mv |
Transplante de fígado Transplante de fígado / mortalidade Unidade de terapia intensiva |
topic |
Transplante de fígado Transplante de fígado / mortalidade Unidade de terapia intensiva |
description |
Background: The goal of this study was to evaluate the predictive factors of mortality in patients after liver transplantation in an intensive care unit from the University Hospital. Methods: This observational study was conducted by using a database analysis of University Hospital. The sample consisted of patients after liver transplantation registered in the database. The study variables of Sequential Organ Failure Assessment score, Acute Physiology and Chronic Health Disease Classification II (APACHE II), Model for End-Stage Liver Disease, and Child-Pugh scores, and the days of hospitalization in intensive care unit, mechanical ventilation time, and reintubation rate, were correlated. Statistical analysis was performed by using the χ2 test or Fisher exact test, the Mann-Whitney test, and logistic regression analysis. Results: Fifty-eight individuals were analyzed. In the death group, the days of hospitalization in the intensive care unit were within 12 ± 14 days, the time of mechanical ventilation was 180 ± 148 hours, the APACHE II value was 17.6 ± 7.3, the Sequential Organ Failure Assessment score was 8.2 ± 2.7, and reintubation was 40%. In the multivariate regression, the predictive indexes of mortality were the mortality given by APACHE II (odds ratio, 1.1; CI, 1.03–1.17; P = .004), mechanical ventilation time (odds ratio, 1.02; CI, 1.01–1.04; P = .001), and reintubation (odds ratio, 9.06; CI, 1.83–44.9; P = .007). An increase of 1 unit in APACHE II mortality increases the risk of death by 10.2%, and each hour of mechanical ventilation increases the risk of death by 2.6%. Conclusions: The time of mechanical ventilation, orotracheal reintubation, and the mortality given by APACHE II were the variables that best predicted death in this study. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-06 |
dc.date.accessioned.fl_str_mv |
2023-01-03T16:51:56Z |
dc.date.available.fl_str_mv |
2023-01-03T16:51:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/48591 |
dc.identifier.doi.pt_BR.fl_str_mv |
https://doi.org/10.1016/j.transproceed.2018.02.087 |
dc.identifier.issn.pt_BR.fl_str_mv |
1873-2623 |
dc.identifier.orcid.pt_BR.fl_str_mv |
https://orcid.org/0000-0002-1165-2149 https://orcid.org/0000-0001-5363-0717 http://orcid.org/0000-0001-9989-4160 http://orcid.org/0000-0003-0949-5516 https://orcid.org/0000-0002-2920-2162 |
url |
https://doi.org/10.1016/j.transproceed.2018.02.087 http://hdl.handle.net/1843/48591 https://orcid.org/0000-0002-1165-2149 https://orcid.org/0000-0001-5363-0717 http://orcid.org/0000-0001-9989-4160 http://orcid.org/0000-0003-0949-5516 https://orcid.org/0000-0002-2920-2162 |
identifier_str_mv |
1873-2623 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Transplantation Proceedings |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.publisher.initials.fl_str_mv |
UFMG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
EEF - DEPARTAMENTO DE FISIOTERAPIA |
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Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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UFMG |
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