Myo1f is critical for neutrophil migration in vivo

Detalhes bibliográficos
Autor(a) principal: Mauro Martins Teixeira
Data de Publicação: 2018
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1182/blood-2018-03-837872
http://hdl.handle.net/1843/37157
https://orcid.org/0000-0002-6944-3008
Resumo: In this issue of Blood, Salvermoser et al demonstrate that the unconventional class I myosin 1f (Myo1f) is crucial for neutrophil trafficking during acute inflammation in vascular beds in vivo. Importantly, they demonstrate that Myo1f is crucial for the dynamics of the deformation of the neutrophil nucleus and consequent capacity of these cells to extravasate in vivo and to negotiate through three-dimensional (3D) environments.
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spelling 2021-08-02T10:08:26Z2021-08-02T10:08:26Z2018-04-261311718791880https://doi.org/10.1182/blood-2018-03-83787215280020http://hdl.handle.net/1843/37157https://orcid.org/0000-0002-6944-3008In this issue of Blood, Salvermoser et al demonstrate that the unconventional class I myosin 1f (Myo1f) is crucial for neutrophil trafficking during acute inflammation in vascular beds in vivo. Importantly, they demonstrate that Myo1f is crucial for the dynamics of the deformation of the neutrophil nucleus and consequent capacity of these cells to extravasate in vivo and to negotiate through three-dimensional (3D) environments.engUniversidade Federal de Minas GeraisUFMGBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAICB - DEPARTAMENTO DE FARMACOLOGIABloodNeutrófilosInfecçõesMiosinasNeutrophilsPolymorphonuclear leukocytesInfectionMyo1fMyo1f is critical for neutrophil migration in vivoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articledoi:10.1182/blood-2018-03-837872Mauro Martins Teixeiraapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/37157/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALMyo1f is critical for neutrophil migration in vivo.pdfMyo1f is critical for neutrophil migration in vivo.pdfapplication/pdf742330https://repositorio.ufmg.br/bitstream/1843/37157/2/Myo1f%20is%20critical%20for%20neutrophil%20migration%20in%20vivo.pdf2882c42e1d4cd61707542d8f92022faeMD521843/371572021-08-02 07:08:27.248oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2021-08-02T10:08:27Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Myo1f is critical for neutrophil migration in vivo
title Myo1f is critical for neutrophil migration in vivo
spellingShingle Myo1f is critical for neutrophil migration in vivo
Mauro Martins Teixeira
Neutrophils
Polymorphonuclear leukocytes
Infection
Myo1f
Neutrófilos
Infecções
Miosinas
title_short Myo1f is critical for neutrophil migration in vivo
title_full Myo1f is critical for neutrophil migration in vivo
title_fullStr Myo1f is critical for neutrophil migration in vivo
title_full_unstemmed Myo1f is critical for neutrophil migration in vivo
title_sort Myo1f is critical for neutrophil migration in vivo
author Mauro Martins Teixeira
author_facet Mauro Martins Teixeira
author_role author
dc.contributor.author.fl_str_mv Mauro Martins Teixeira
dc.subject.por.fl_str_mv Neutrophils
Polymorphonuclear leukocytes
Infection
Myo1f
topic Neutrophils
Polymorphonuclear leukocytes
Infection
Myo1f
Neutrófilos
Infecções
Miosinas
dc.subject.other.pt_BR.fl_str_mv Neutrófilos
Infecções
Miosinas
description In this issue of Blood, Salvermoser et al demonstrate that the unconventional class I myosin 1f (Myo1f) is crucial for neutrophil trafficking during acute inflammation in vascular beds in vivo. Importantly, they demonstrate that Myo1f is crucial for the dynamics of the deformation of the neutrophil nucleus and consequent capacity of these cells to extravasate in vivo and to negotiate through three-dimensional (3D) environments.
publishDate 2018
dc.date.issued.fl_str_mv 2018-04-26
dc.date.accessioned.fl_str_mv 2021-08-02T10:08:26Z
dc.date.available.fl_str_mv 2021-08-02T10:08:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/37157
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1182/blood-2018-03-837872
dc.identifier.issn.pt_BR.fl_str_mv 15280020
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0002-6944-3008
url https://doi.org/10.1182/blood-2018-03-837872
http://hdl.handle.net/1843/37157
https://orcid.org/0000-0002-6944-3008
identifier_str_mv 15280020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Blood
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv ICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIA
ICB - DEPARTAMENTO DE FARMACOLOGIA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
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institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
bitstream.url.fl_str_mv https://repositorio.ufmg.br/bitstream/1843/37157/1/License.txt
https://repositorio.ufmg.br/bitstream/1843/37157/2/Myo1f%20is%20critical%20for%20neutrophil%20migration%20in%20vivo.pdf
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