Hematological and biochemical alterations in female dogs with mammary cancer and inflammatory carcinoma

• Autor(a) principal: M.R. Oliveira
• Data de Publicação: 2022
• Outros Autores: Rubens A. Carneiro, F.C. Nunes, S.V. Teixeira, T.C. Vieira, Gleidice Eunice Lavalle, Geovanni Dantas Cassali
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: https://doi.org/10.1590/1678-4162-12471; http://hdl.handle.net/1843/61323; https://orcid.org/0000-0003-2297-7384; https://orcid.org/0000-0002-5920-0483; https://orcid.org/0000-0002-5286-5749; https://orcid.org/0000-0001-6795-7526; https://orcid.org/0000-0002-5952-1199; https://orcid.org/0000-0002-2701-9954; https://orcid.org/0000-0002-5650-6743
• topic: Caninos; Câncer de mama; Hemograma; Bioquímica sérica; Animais domésticos; Neoplasias da Mama; Bioquímica

Hematological and biochemical alterations in animals with neoplasms may result from the direct effects of tumor growth or paraneoplastic syndromes. The objective of this study was to evaluate these hematological and biochemical alterations in female dogs with mammary tumors and with inflammatory carcinoma (IC). Blood samples were collected from 43 female dogs divided into three groups according to clinical staging: Group 1 (G1) - animals in initial stage (T1,2,3N0M0, N=17), Group 2 (G2) - animals in advanced stage (T1,2,3N1M0,1, N=15) and Group 3 (G3) - animals presenting IC (N=11). Hematological and biochemical parameters obtained were related to patients' clinical staging. Among alterations, the most common were anemia, neutrophilic leukocytosis, monocytosis, increased ALT, AST, and hypoalbuminemia, mainly in dogs in advanced clinical staging and with inflammatory carcinoma.