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Antônio Último de Carvalhohttp://lattes.cnpq.br/7281338403430073Elias Jorge Facury FilhoFabíola de Oliveira Paes LemeMoisés Dias Freitashttp://lattes.cnpq.br/8013804472964682Isabela Oliveira Melo2020-02-27T14:33:21Z2020-02-27T14:33:21Z2018-02-08http://hdl.handle.net/1843/32611https://orcid.org/0000-0001-7004-3274A sobrevivência dos animais acometidos com Anaplasma marginale depende de sua capacidade de manter o equilíbrio hidroeletrolítico e ácido-base. Objetivou-se avaliar o comportamento do perfil hidroeletrolítico e ácido-base durante a fase de patência e convalescência de bezerros inoculados com A. marginale. Foram utilizados 12 bezerros machos, com idade de 3 a 4 meses. Os animais foram divididos em grupo inoculado (n=6) com 108 hemácias parasitadas com isolado de UFMG1 de A. marginale, por via intravenosa (IV) e grupo controle (n=6). Os animais foram avaliados nos períodos pré patente e no período patente quando o volume globular(VG) reduziu para 80, 60 e 40% do VG basal. A avaliação foi realizada também no período convalescente quando o VG recuperou para 60 e 80 % do VG basal. Foram avaliados o hemograma, o perfil ácido- base, eletrolítico e bioquímico. Para testar as diferenças entre os grupos, ajustou-se um modelo de regressão de efeitos mistos utilizando software estatístico R com nível de significância de 0,05 (P ≤0,05). Durante a fase de patência da anaplasmose ocorreu anemia grave, resultando em alcalose respiratória, com aumento do pH sanguíneo e redução da pressão de gás carbonico. A anaplasmose não influenciou o perfil hidroeletrolítico durante a fase de patência e convalescência.The survival of animals infected by Anaplasma marginale depends on its capacity to maintain the hydroelectrolytic and acid-base equilibrium. The objective of this work was to evaluate the behavior of the hydroelectrolytic and acid-base profile during the phases of patency and convalescence in calves affected by anaplasmosis. In this experiment, 12 male calves were used, aged between 3 and 4 months. The animals were divided into two groups: One inoculated (n=6) with 108 erythrocytes containing the isolate UFMG1 of A. marginale, administered intravenously (IV) and the control group (n=6). The animals were evaluated in the pre-patency and patency period when the packed cell volume (PCV) decreased to 80, 60 and 40% of the baseline value. The evaluation was also performed in the convalescence period in which the VG recovered to 60 and 80% of the baseline value. The hemogram, acid-base, hydroelectrolytic and biochemical profile were evaluated. To test the differences between groups, a model of mix effects was adjusted using a statistical software R with a level of significance of 0,05 (p≤0,05). During the phase of patency, a severe anemia happen leading to respiratory alkalosis, with increased blood pH and reduction of PCO2. The anaplasmosis had no influence in the hydroelectrolytic profile in neither patency nor convalescence phase.CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorporUniversidade Federal de Minas GeraisPrograma de Pós-Graduação em Ciência AnimalUFMGBrasilVET - DEPARTAMENTO DE CLÍNICA E CIRURGIABovinosGasometriaHematologiaAnaplasmosePerfil laboratorial longitudinal de bezerros com anaplasmose experimentalLongitudinal laboratory profile of calves with experimental anaplasmosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGORIGINALDissertação Isabela O Melopdf.pdfDissertação Isabela O Melopdf.pdfapplication/pdf2007891https://repositorio.ufmg.br/bitstream/1843/32611/1/Disserta%c3%a7%c3%a3o%20Isabela%20O%20Melopdf.pdf455ea2b7e7f127bc1380e4843a204829MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82119https://repositorio.ufmg.br/bitstream/1843/32611/2/license.txt34badce4be7e31e3adb4575ae96af679MD52TEXTDissertação Isabela O Melopdf.pdf.txtDissertação Isabela O Melopdf.pdf.txtExtracted texttext/plain193243https://repositorio.ufmg.br/bitstream/1843/32611/3/Disserta%c3%a7%c3%a3o%20Isabela%20O%20Melopdf.pdf.txtf06a828771dbbfaefc92367dd5e942e5MD531843/326112020-02-28 03:38:15.446oai:repositorio.ufmg.br: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Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oaiopendoar:2020-02-28T06:38:15Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
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