Factors related to amputation level and wound healing in diabetic patients

Detalhes bibliográficos
Autor(a) principal: Daniel Soares Baumfeld
Data de Publicação: 2018
Outros Autores: Tiago Baumfeld, Benjamim Macedo, Roberto Zambelli, Fernando Lopes, Caio Nery
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/59204
Resumo: Objective: There are no specific criteria that define the level of amputation in diabetic patients. The objective of this study was to assess the influence of clinical and laboratory parameters in determining the level of amputation and the wound healing time. Methods: One hundred and thirty-nine diabetic patients were retrospectively assessed. They underwent surgical procedures due to infection and/or ischemic necrosis. Type of surgery, antibiotic use, laboratory parameters and length of hospital stay were eval uated in this study. Results: The most common amputation level was transmetatarsal, occurring in 26 patients (28.9%). The wound healing time increased with statistical significance in individuals undergoing debridement, who did not receive preoperative antibiotics and did not undergo vascular intervention. Higher levels of amputation were statistically related to limb ischemia, previous amputation and non-use of preoperative antibiotics. Conclusion: Patients with minor amputations undergo stump revision surgery more often, but the act of always targeting the most distal stump possible decreases energy expenditure while walking, allowing patients to achieve better quality of life. Risk factors for major amputations were ischemia and previous amputations. A protective factor was preoperative antibiotic therapy. Level of Evidence III, Retrospective Study
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spelling 2023-10-05T22:09:39Z2023-10-05T22:09:39Z2018-03-0726534234510.1590/1413-78522018260517344518094406http://hdl.handle.net/1843/59204Objective: There are no specific criteria that define the level of amputation in diabetic patients. The objective of this study was to assess the influence of clinical and laboratory parameters in determining the level of amputation and the wound healing time. Methods: One hundred and thirty-nine diabetic patients were retrospectively assessed. They underwent surgical procedures due to infection and/or ischemic necrosis. Type of surgery, antibiotic use, laboratory parameters and length of hospital stay were eval uated in this study. Results: The most common amputation level was transmetatarsal, occurring in 26 patients (28.9%). The wound healing time increased with statistical significance in individuals undergoing debridement, who did not receive preoperative antibiotics and did not undergo vascular intervention. Higher levels of amputation were statistically related to limb ischemia, previous amputation and non-use of preoperative antibiotics. Conclusion: Patients with minor amputations undergo stump revision surgery more often, but the act of always targeting the most distal stump possible decreases energy expenditure while walking, allowing patients to achieve better quality of life. Risk factors for major amputations were ischemia and previous amputations. A protective factor was preoperative antibiotic therapy. Level of Evidence III, Retrospective StudyObjetivos: Não há critérios específicos que definam o nível de amputação em pacientes diabéticos. O objetivo deste estudo foi avaliar a influência de parâmetros clínicos e laboratoriais na determinação do nível de amputação e do tempo de cicatrização da ferida. Métodos: Centro e trinta e nove pacientes diabéticos foram avaliados retrospectivamente. Eles foram submetidos a procedimentos cirúrgicos devido a infecção e/ou necrose isquêmica. Este estudo avaliou tipo de cirurgia, uso de antibióticos, parâmetros laboratoriais e tempo de internação. Resultados: O nível de amputação mais comum foi o transmetatarsal, ocorrendo em 26 pacientes (28,9%). O tempo de cicatrização das feridas aumentou com significância estatística em indivíduos submetidos a desbridamento que não usaram antibióticos pré-operatórios e que não foram submetidos à intervenção vascular. Os níveis mais altos de amputação foram estatisticamente relacionados a isquemia do membro, amputação prévia e ausência de antibiótico no pré-operatório. Conclusão: Os pacientes com amputações menores são submetidos à revisão do coto com maior frequência, porém, visar sempre o coto mais distal possível diminui o gasto de energia durante a marcha, possibilitando melhor qualidade de vida aos pacientes. Os fatores de risco de amputação maior foram isquemia e amputações prévias. Um fator de proteção foi a antibioticoterapia no pré-operatório.Nível de evidência III, Estudo RetrospectivoengUniversidade Federal de Minas GeraisUFMGBrasilMED - DEPARTAMENTO DE APARELHO LOCOMOTORActa Ortopédica BrasileiraDiabetic FootAmputation, SurgicalAntifungal AgentsWound healingRisk factorsProtective FactorsDiabetic footAmputationAntibiotics.Wound healingRisk factorsProtective FactorsFactors related to amputation level and wound healing in diabetic patientsFatores relacionados ao nível de amputação e a cicatrização de feridas em pacientes diabéticosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://pubmed.ncbi.nlm.nih.gov/30464719/Daniel Soares BaumfeldTiago BaumfeldBenjamim MacedoRoberto ZambelliFernando LopesCaio Neryapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/59204/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALFACTORS RELATED TO AMPUTATION LEVEL AND WOUND pdfa.pdfFACTORS RELATED TO AMPUTATION LEVEL AND WOUND pdfa.pdfapplication/pdf183019https://repositorio.ufmg.br/bitstream/1843/59204/2/FACTORS%20RELATED%20TO%20AMPUTATION%20LEVEL%20AND%20WOUND%20pdfa.pdf9458183ac562fd7d0b015f8db66dfffdMD521843/592042023-10-05 19:13:36.829oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-10-05T22:13:36Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Factors related to amputation level and wound healing in diabetic patients
dc.title.alternative.pt_BR.fl_str_mv Fatores relacionados ao nível de amputação e a cicatrização de feridas em pacientes diabéticos
title Factors related to amputation level and wound healing in diabetic patients
spellingShingle Factors related to amputation level and wound healing in diabetic patients
Daniel Soares Baumfeld
Diabetic foot
Amputation
Antibiotics.
Wound healing
Risk factors
Protective Factors
Diabetic Foot
Amputation, Surgical
Antifungal Agents
Wound healing
Risk factors
Protective Factors
title_short Factors related to amputation level and wound healing in diabetic patients
title_full Factors related to amputation level and wound healing in diabetic patients
title_fullStr Factors related to amputation level and wound healing in diabetic patients
title_full_unstemmed Factors related to amputation level and wound healing in diabetic patients
title_sort Factors related to amputation level and wound healing in diabetic patients
author Daniel Soares Baumfeld
author_facet Daniel Soares Baumfeld
Tiago Baumfeld
Benjamim Macedo
Roberto Zambelli
Fernando Lopes
Caio Nery
author_role author
author2 Tiago Baumfeld
Benjamim Macedo
Roberto Zambelli
Fernando Lopes
Caio Nery
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Daniel Soares Baumfeld
Tiago Baumfeld
Benjamim Macedo
Roberto Zambelli
Fernando Lopes
Caio Nery
dc.subject.por.fl_str_mv Diabetic foot
Amputation
Antibiotics.
Wound healing
Risk factors
Protective Factors
topic Diabetic foot
Amputation
Antibiotics.
Wound healing
Risk factors
Protective Factors
Diabetic Foot
Amputation, Surgical
Antifungal Agents
Wound healing
Risk factors
Protective Factors
dc.subject.other.pt_BR.fl_str_mv Diabetic Foot
Amputation, Surgical
Antifungal Agents
Wound healing
Risk factors
Protective Factors
description Objective: There are no specific criteria that define the level of amputation in diabetic patients. The objective of this study was to assess the influence of clinical and laboratory parameters in determining the level of amputation and the wound healing time. Methods: One hundred and thirty-nine diabetic patients were retrospectively assessed. They underwent surgical procedures due to infection and/or ischemic necrosis. Type of surgery, antibiotic use, laboratory parameters and length of hospital stay were eval uated in this study. Results: The most common amputation level was transmetatarsal, occurring in 26 patients (28.9%). The wound healing time increased with statistical significance in individuals undergoing debridement, who did not receive preoperative antibiotics and did not undergo vascular intervention. Higher levels of amputation were statistically related to limb ischemia, previous amputation and non-use of preoperative antibiotics. Conclusion: Patients with minor amputations undergo stump revision surgery more often, but the act of always targeting the most distal stump possible decreases energy expenditure while walking, allowing patients to achieve better quality of life. Risk factors for major amputations were ischemia and previous amputations. A protective factor was preoperative antibiotic therapy. Level of Evidence III, Retrospective Study
publishDate 2018
dc.date.issued.fl_str_mv 2018-03-07
dc.date.accessioned.fl_str_mv 2023-10-05T22:09:39Z
dc.date.available.fl_str_mv 2023-10-05T22:09:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/59204
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/1413-785220182605173445
dc.identifier.issn.pt_BR.fl_str_mv 18094406
identifier_str_mv 10.1590/1413-785220182605173445
18094406
url http://hdl.handle.net/1843/59204
dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.none.fl_str_mv Acta Ortopédica Brasileira
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dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv MED - DEPARTAMENTO DE APARELHO LOCOMOTOR
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
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instname_str Universidade Federal de Minas Gerais (UFMG)
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institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
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