Bioactive Extracts from Annona hypoglauca
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFMG |
| Texto Completo: | https://doi.org/10.3303/CET1864049 http://hdl.handle.net/1843/59496 https://orcid.org/0000-0002-8831-1609 |
Resumo: | CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico |
| id |
UFMG_c52c1b6133d33e2bf6eb0563e096ff8e |
|---|---|
| oai_identifier_str |
oai:repositorio.ufmg.br:1843/59496 |
| network_acronym_str |
UFMG |
| network_name_str |
Repositório Institucional da UFMG |
| repository_id_str |
|
| spelling |
2023-10-16T21:47:30Z2023-10-16T21:47:30Z201864289294https://doi.org/10.3303/CET18640492283-9216http://hdl.handle.net/1843/59496https://orcid.org/0000-0002-8831-1609CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorThe aim was to analyze the bioactive potential of hexane and ethanolic extracts from leaves of Annona hypoglauca, Roraima, Brazil, against fungi (Aspergillus flavus and Fusarium proliferatum) and yeast (Candida albicans) and gram-positive bacteria (Staphylococcus aureus and Streptococcus sanguinis) and gramnegative (Escherichia coli and Salmonella typhimurium), antioxidant, antiacetylcholinesterase and cytotoxic activities against Artemia salina, in addition to verify a phytochemical screening. Antioxidant activity of the leaves ethanolic extract 51% to 50 μg mL-1, 16% at the same concentration for the hexane extract. The antiacetylcholinesterase activity presented high variation of the ethanolic extract and 59.76% in the hexane extract. The cytotoxic activity against A. salina was more efficient for the ethanolic extract of the leaves in 27% to 500 μg mL-1. The bioactivity of fungi and yeasts, the ethanolic extract of the leaves of A. hypoglauca showed no inhibition on the fungi F. proliferatum and A. flavus, but the hexane extract inhibited 40.0% and 59.5% on these fungi, respectively. For the inhibition of C. albicans, the extracts hexane (94.5-96.9%) and ethanolic (89.2-92.6%) of the leaves of A. hypoglauca, at all concentrations. Excellent inhibitions on grampositive bacteria were given by the hexane extract in 100% to 500 μg mL-1, but low inhibition for the ethanolic extract for S. aureus in 21.6% to 125 μg mL-1 and for S. Sanguinis 35.5% to 500 μg mL-1. Inhibitions on gramnegative bacteria varied from 26.1% to 42.4% in ethanolic extract and 10.7% to 18.6% in hexanic extract for E. coli; as inhibition of S. typhimurium occurred from 9.3% to 61.1% in ethanolic extract and from 9.1% to 41.2% in hexane extract. Regarding phytochemical screening, the class of compounds observed qualitatively suggests the presence of saponins, flavonoids, triterpenoids and tannins.engUniversidade Federal de Minas GeraisUFMGBrasilICX - DEPARTAMENTO DE QUÍMICAChemical Engineering TransactionsQuímicaCompostos bioativosQuímicaCompostos bioativosBioactive Extracts from Annona hypoglaucainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.aidic.it/cet/18/64/049.pdfRicardo C. dos SantosEdvan Alves ChagasAntônio A. de Melo FilhoJacqueline Aparecida TakahashiIsmael Montero FernandezPollyana C. ChagasPedro R. E. RibeiroAna Cristina Gonçalves Reis Meloapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/59496/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALBioactive Extracts from Annona hypoglauca.pdfBioactive Extracts from Annona hypoglauca.pdfapplication/pdf327634https://repositorio.ufmg.br/bitstream/1843/59496/2/Bioactive%20Extracts%20from%20Annona%20hypoglauca.pdf244171b99c7c323393712e1748fa1da4MD521843/594962023-10-16 18:47:30.651oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-10-16T21:47:30Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.pt_BR.fl_str_mv |
Bioactive Extracts from Annona hypoglauca |
| title |
Bioactive Extracts from Annona hypoglauca |
| spellingShingle |
Bioactive Extracts from Annona hypoglauca Ricardo C. dos Santos Química Compostos bioativos Química Compostos bioativos |
| title_short |
Bioactive Extracts from Annona hypoglauca |
| title_full |
Bioactive Extracts from Annona hypoglauca |
| title_fullStr |
Bioactive Extracts from Annona hypoglauca |
| title_full_unstemmed |
Bioactive Extracts from Annona hypoglauca |
| title_sort |
Bioactive Extracts from Annona hypoglauca |
| author |
Ricardo C. dos Santos |
| author_facet |
Ricardo C. dos Santos Edvan Alves Chagas Antônio A. de Melo Filho Jacqueline Aparecida Takahashi Ismael Montero Fernandez Pollyana C. Chagas Pedro R. E. Ribeiro Ana Cristina Gonçalves Reis Melo |
| author_role |
author |
| author2 |
Edvan Alves Chagas Antônio A. de Melo Filho Jacqueline Aparecida Takahashi Ismael Montero Fernandez Pollyana C. Chagas Pedro R. E. Ribeiro Ana Cristina Gonçalves Reis Melo |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Ricardo C. dos Santos Edvan Alves Chagas Antônio A. de Melo Filho Jacqueline Aparecida Takahashi Ismael Montero Fernandez Pollyana C. Chagas Pedro R. E. Ribeiro Ana Cristina Gonçalves Reis Melo |
| dc.subject.por.fl_str_mv |
Química Compostos bioativos |
| topic |
Química Compostos bioativos Química Compostos bioativos |
| dc.subject.other.pt_BR.fl_str_mv |
Química Compostos bioativos |
| description |
CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico |
| publishDate |
2018 |
| dc.date.issued.fl_str_mv |
2018 |
| dc.date.accessioned.fl_str_mv |
2023-10-16T21:47:30Z |
| dc.date.available.fl_str_mv |
2023-10-16T21:47:30Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/59496 |
| dc.identifier.doi.pt_BR.fl_str_mv |
https://doi.org/10.3303/CET1864049 |
| dc.identifier.issn.pt_BR.fl_str_mv |
2283-9216 |
| dc.identifier.orcid.pt_BR.fl_str_mv |
https://orcid.org/0000-0002-8831-1609 |
| url |
https://doi.org/10.3303/CET1864049 http://hdl.handle.net/1843/59496 https://orcid.org/0000-0002-8831-1609 |
| identifier_str_mv |
2283-9216 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.pt_BR.fl_str_mv |
Chemical Engineering Transactions |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
| dc.publisher.initials.fl_str_mv |
UFMG |
| dc.publisher.country.fl_str_mv |
Brasil |
| dc.publisher.department.fl_str_mv |
ICX - DEPARTAMENTO DE QUÍMICA |
| publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
| instname_str |
Universidade Federal de Minas Gerais (UFMG) |
| instacron_str |
UFMG |
| institution |
UFMG |
| reponame_str |
Repositório Institucional da UFMG |
| collection |
Repositório Institucional da UFMG |
| bitstream.url.fl_str_mv |
https://repositorio.ufmg.br/bitstream/1843/59496/1/License.txt https://repositorio.ufmg.br/bitstream/1843/59496/2/Bioactive%20Extracts%20from%20Annona%20hypoglauca.pdf |
| bitstream.checksum.fl_str_mv |
fa505098d172de0bc8864fc1287ffe22 244171b99c7c323393712e1748fa1da4 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
| repository.mail.fl_str_mv |
|
| _version_ |
1803589510589579264 |