Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review

Detalhes bibliográficos
Autor(a) principal: Carolina de Castro Martins
Data de Publicação: 2022
Outros Autores: John Joseph Riva, Ramon Targino Firmino, Holger Jens Schünemann
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://dx.doi.org/10.1590/1678-7757-2021-0410
http://hdl.handle.net/1843/68088
Resumo: CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
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spelling 2024-05-06T19:11:17Z2024-05-06T19:11:17Z202230e20210410http://dx.doi.org/10.1590/1678-7757-2021-04101678-7765http://hdl.handle.net/1843/68088CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorObjective: This study aimed to review evidence from randomized controlled trials (RCTs) to describe: 1) the active ingredients and desensitizing toothpaste brands; 2) the evaluation of these active ingredients over time, and 3) the fluoride and abrasive content in the formulations designed to treat dentin hypersensitivity (DH). Methodology: In total, 138 RCTs and their tested toothpastes were included. Searches were updated up to August 19, 2021. Formulations, reported brands, active ingredients over time, and type of fluoride (ionizable or ionic fluoride) and abrasive (calcium or silica-based) were analyzed (PROSPERO #CRD42018086815). Results: Our trials assessed 368 toothpaste formulations, including 34 placebo (9%), 98 control toothpastes with fluoride (27%), and 236 (64%) with active ingredients to treat DH. We tested the following active ingredients: potassium compounds (n=68, 19%), calcium sodium phosphosilicate (CSP) (n=37, 10%), strontium compounds (n=28, 8%), arginine (n=29, 8%), stannous fluoride (SnF2) (n=21, 6%), hydroxyapatite (n=9, 2%), potassium combined with another active ingredient (n=19, 5%), inorganic salt compounds (n=11, 3%), citrate (n=5, 1%), formaldehyde (n=3, 1%), herbal (n=4, 1%), copolymer (n=1, 0.5%), and trichlorophosphate (TCP) (n=1, 0.5%). The number of toothpaste formulations increased since 1968, with the greatest increment after 2010. Most toothpastes described their type of fluoride as sodium monofluorphosphate (MFP) (n=105, 29%) and NaF (n=82, 22%), with silica-based (n=84, 23%) and calcium-based (n=64, 17%) abrasives. Conclusion: Patients and dentists enjoy an increasing number of brands and active ingredients to decide what desensitizing toothpaste to use. The most common types of fluoride are MFP and NaF.engUniversidade Federal de Minas GeraisUFMGBrasilFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIAJournal of Applied Oral ScienceSystematic reviewNetwork meta-analysisMeta-analysisDentin sensitivityDentifricesSystematic reviewNetwork meta-analysisMeta-analysisDentine sensitivityDentifriceFormulations of desensitizing toothpastes for dentin hypersensitivity: a scoping reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/jaos/a/nVwXH8tM8M8tbjvcHb4Pkpy/?lang=enCarolina de Castro MartinsJohn Joseph RivaRamon Targino FirminoHolger Jens Schünemannapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/68088/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALFormulations of desensitizing toothpastes for dentin hypersensitivity - A scoping review.pdfFormulations of desensitizing toothpastes for dentin hypersensitivity - A scoping review.pdfapplication/pdf722293https://repositorio.ufmg.br/bitstream/1843/68088/2/Formulations%20of%20desensitizing%20toothpastes%20for%20dentin%20hypersensitivity%20-%20A%20scoping%20review.pdf3878e83588bff57bb5ffe8cb03bf7cc9MD521843/680882024-05-06 17:37:48.77oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2024-05-06T20:37:48Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
title Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
spellingShingle Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
Carolina de Castro Martins
Systematic review
Network meta-analysis
Meta-analysis
Dentine sensitivity
Dentifrice
Systematic review
Network meta-analysis
Meta-analysis
Dentin sensitivity
Dentifrices
title_short Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
title_full Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
title_fullStr Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
title_full_unstemmed Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
title_sort Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review
author Carolina de Castro Martins
author_facet Carolina de Castro Martins
John Joseph Riva
Ramon Targino Firmino
Holger Jens Schünemann
author_role author
author2 John Joseph Riva
Ramon Targino Firmino
Holger Jens Schünemann
author2_role author
author
author
dc.contributor.author.fl_str_mv Carolina de Castro Martins
John Joseph Riva
Ramon Targino Firmino
Holger Jens Schünemann
dc.subject.por.fl_str_mv Systematic review
Network meta-analysis
Meta-analysis
Dentine sensitivity
Dentifrice
topic Systematic review
Network meta-analysis
Meta-analysis
Dentine sensitivity
Dentifrice
Systematic review
Network meta-analysis
Meta-analysis
Dentin sensitivity
Dentifrices
dc.subject.other.pt_BR.fl_str_mv Systematic review
Network meta-analysis
Meta-analysis
Dentin sensitivity
Dentifrices
description CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2024-05-06T19:11:17Z
dc.date.available.fl_str_mv 2024-05-06T19:11:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/68088
dc.identifier.doi.pt_BR.fl_str_mv http://dx.doi.org/10.1590/1678-7757-2021-0410
dc.identifier.issn.pt_BR.fl_str_mv 1678-7765
url http://dx.doi.org/10.1590/1678-7757-2021-0410
http://hdl.handle.net/1843/68088
identifier_str_mv 1678-7765
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Journal of Applied Oral Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
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https://repositorio.ufmg.br/bitstream/1843/68088/2/Formulations%20of%20desensitizing%20toothpastes%20for%20dentin%20hypersensitivity%20-%20A%20scoping%20review.pdf
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