Modelagem do ouvido na otosclerose

Detalhes bibliográficos
Autor(a) principal: Lygia Bueno Fragoso
Data de Publicação: 2013
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFMG
Texto Completo: http://hdl.handle.net/1843/PASA-9BLGNZ
Resumo: Introduction: Otosclerosis is a hereditary disease that affects from about 0.5 to 1% of the population. It is bilateral in most of cases. A major symptom is hearing loss. Biomechanical studies that simulate otosclerosis are poorly described in the literature. Objective: Simulate otosclerosis using a one-dimensional mass-spring model and create one tridimensional geometric model of the ear. Methods: The one-dimensional mass-spring model consists of six masses (air volume of the external ear canal, eardrum, malleus, incus, stapes and cochlear fluid), plus springs and dashpots simulating the ligaments and muscles supporting. In this study, we simulated otosclerosis by an increase of 10 to 100 times of the stapedial annulus ligament stiffness and an increase by 5 times of the stapes mass. The three-dimensional model was contructed using a sample of three ear bones, malleus, incus and stapes, originated from the Institute of Biological Sciences, UFMG. The ear bones were taken to the laboratory and Ceramic Materials UFMG for conducting a test image using the X-ray SkyScan 1172. The images obtained from the three bones were imported into an image processing program, Simpleware ®, which digitally reconstructed three ear bones resulting in a three-dimensional geometric model for each of them. The geometric models of the bones were imported into Rapidform software XOR / Redesign which is capable of producing solid models with a smaller amount of data. The tympanic membrane and the ligaments were inserted along with geometric models of the bones, using SolidWorks 19.4, computer aided design software, according to the anatomical parameters found in the literature. Results: In the one-dimensional model stapes displacement were reduced at lower frequencies with increasing stiffness of the stapedial annulus ligament and reducing the displacement of the stapes in high frequencies with increased its mass. The increase of stapedial annulus ligament stiffness may be related to the initial stage of the disease, from the viewpoint audiometric, while increased bone tissue volume suggests a progression of the disease. In the three-dimensional model was possible to obtain a geometry compatible with the anatomy of the middle ear. Conclusion: The results of the one-dimensional model met the audiological findings that suggest the disease and the need for early diagnosis of the annular ligament of the stapes in order to detect as soon as the hearing loss caused by your changes. The tridimensional geometric model of the ear can be used to simulate dynamic behavior using finite-element method to understand the normal hearing, pathology and tratament.
id UFMG_d96879d5e272d4841da7c014224919e2
oai_identifier_str oai:repositorio.ufmg.br:1843/PASA-9BLGNZ
network_acronym_str UFMG
network_name_str Repositório Institucional da UFMG
repository_id_str
spelling Modelagem do ouvido na otoscleroseOuvido médioBiomecânicaOtoscleroseMecânica computacionalEngenharia de estruturasIntroduction: Otosclerosis is a hereditary disease that affects from about 0.5 to 1% of the population. It is bilateral in most of cases. A major symptom is hearing loss. Biomechanical studies that simulate otosclerosis are poorly described in the literature. Objective: Simulate otosclerosis using a one-dimensional mass-spring model and create one tridimensional geometric model of the ear. Methods: The one-dimensional mass-spring model consists of six masses (air volume of the external ear canal, eardrum, malleus, incus, stapes and cochlear fluid), plus springs and dashpots simulating the ligaments and muscles supporting. In this study, we simulated otosclerosis by an increase of 10 to 100 times of the stapedial annulus ligament stiffness and an increase by 5 times of the stapes mass. The three-dimensional model was contructed using a sample of three ear bones, malleus, incus and stapes, originated from the Institute of Biological Sciences, UFMG. The ear bones were taken to the laboratory and Ceramic Materials UFMG for conducting a test image using the X-ray SkyScan 1172. The images obtained from the three bones were imported into an image processing program, Simpleware ®, which digitally reconstructed three ear bones resulting in a three-dimensional geometric model for each of them. The geometric models of the bones were imported into Rapidform software XOR / Redesign which is capable of producing solid models with a smaller amount of data. The tympanic membrane and the ligaments were inserted along with geometric models of the bones, using SolidWorks 19.4, computer aided design software, according to the anatomical parameters found in the literature. Results: In the one-dimensional model stapes displacement were reduced at lower frequencies with increasing stiffness of the stapedial annulus ligament and reducing the displacement of the stapes in high frequencies with increased its mass. The increase of stapedial annulus ligament stiffness may be related to the initial stage of the disease, from the viewpoint audiometric, while increased bone tissue volume suggests a progression of the disease. In the three-dimensional model was possible to obtain a geometry compatible with the anatomy of the middle ear. Conclusion: The results of the one-dimensional model met the audiological findings that suggest the disease and the need for early diagnosis of the annular ligament of the stapes in order to detect as soon as the hearing loss caused by your changes. The tridimensional geometric model of the ear can be used to simulate dynamic behavior using finite-element method to understand the normal hearing, pathology and tratament.Introdução: A otosclerose é uma doença hereditária, que atinge cerca de 0,5 a 1% da população, sendo bilateral na maioria dos casos. Um dos principais sintomas é a perda da audição, importante no processo de comunicação que constitui uma necessidade básica do ser humano. Estudos biomecânicos que simulam a otosclerose são pouco descritos na literatura científica. Objetivo: Simular a otosclerose usando um modelo massa-mola unidimensional e desenvolver um modelo geométrico tridimensional do ouvido. Metodologia: O modelo unidimensional massa-mola é formado por seis massas (volume de ar do conduto auditivo externo, tímpano, martelo, bigorna, estribo e fluidos cocleares), além de molas e amortecedos que simulam os ligamentos e músculos de sustentação. Simulou-se a otosclerose no modelo proposto a partir das características que a doença apresenta e com isso aumentou-se da rigidez de 10 e 100 vezes no ligamento anular do estribo e aumento da massa do estribo em 5 vezes. Para a construção do modelo tridimensional utilizou-se uma amostra de três ossos do ouvido, martelo, bigorna e estribo oriundo do Instituto de Ciências Biológicas da UFMG. Os ossos foram levados para o laboratório de Materiais e Cerâmicos da UFMG para realização de uma exame de imagem com a utilização do microtomógrafo de raios X SkyScan 1172. As imagens dos três ossos obtidas foram importadas para um programa de processamento de imagens Simpleware®, que reconstruiu digitalmente os três ossos do ouvido resultando em um modelo geométrico tridimensional para cada um deles. Os modelos geométricos dos ossos foram importados para o programa Rapidform XOR/Redesign que é capaz de gerar modelos sólidos, com uma menor quantidade de dados. A membrana timpânica e os ligamentos foram inseridos juntamente com os modelos geométricos dos ossos, no programa SolidWorks 19.4, software de desenho assistido por computador de acordo com os parâmetros anatômicos encontrados na literatura. Resultados: No modelo unidimensional houve uma diminuição do deslocamento do estribo nas freqüências graves com o aumento da rigidez do ligamento anular do estribo e uma redução do deslocamento do estribo nas freqüências agudas com aumento da sua massa. O aumento da rigidez do ligamento anular do estribo pode estar relacionado ao estágio inicial da doença, do ponto de vista audiométrico, enquanto que o aumento de tecido ósseo sugere um avanço da doença. No modelo tridimensional foi possível obter uma geometria compatível com a anatomia do ouvido médio e semelhante aos modelos já validados na literatura. Conclusão: Os resultados do modelo unidimensional vão ao encontro dos achados audiológicos da doença e sugerem a necessidade de obter um diagnóstico precoce do ligamento anular do estribo, a fim de detectar o quanto antes as perdas auditivas ocasionadas por suas alterações. O modelo geométrico tridimensional do ouvido poderá ser útil para posterior simulação do seu comportamento dinâmico usando o método dos elementos finitos em programas de engenharia assistida a fim de melhor compreender a audição normal e com otosclerose, simular patologias e possíveis formas de tratamento.Universidade Federal de Minas GeraisUFMGEstevam Barbosa de Las CasasMax de Castro MagalhaesMax de Castro MagalhaesMarcelo GrecoHani Camille YeniaJuliana Nunes SantosLygia Bueno Fragoso2019-08-11T01:02:20Z2019-08-11T01:02:20Z2013-04-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/1843/PASA-9BLGNZinfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2019-11-14T12:36:24Zoai:repositorio.ufmg.br:1843/PASA-9BLGNZRepositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2019-11-14T12:36:24Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Modelagem do ouvido na otosclerose
title Modelagem do ouvido na otosclerose
spellingShingle Modelagem do ouvido na otosclerose
Lygia Bueno Fragoso
Ouvido médio
Biomecânica
Otosclerose
Mecânica computacional
Engenharia de estruturas
title_short Modelagem do ouvido na otosclerose
title_full Modelagem do ouvido na otosclerose
title_fullStr Modelagem do ouvido na otosclerose
title_full_unstemmed Modelagem do ouvido na otosclerose
title_sort Modelagem do ouvido na otosclerose
author Lygia Bueno Fragoso
author_facet Lygia Bueno Fragoso
author_role author
dc.contributor.none.fl_str_mv Estevam Barbosa de Las Casas
Max de Castro Magalhaes
Max de Castro Magalhaes
Marcelo Greco
Hani Camille Yenia
Juliana Nunes Santos
dc.contributor.author.fl_str_mv Lygia Bueno Fragoso
dc.subject.por.fl_str_mv Ouvido médio
Biomecânica
Otosclerose
Mecânica computacional
Engenharia de estruturas
topic Ouvido médio
Biomecânica
Otosclerose
Mecânica computacional
Engenharia de estruturas
description Introduction: Otosclerosis is a hereditary disease that affects from about 0.5 to 1% of the population. It is bilateral in most of cases. A major symptom is hearing loss. Biomechanical studies that simulate otosclerosis are poorly described in the literature. Objective: Simulate otosclerosis using a one-dimensional mass-spring model and create one tridimensional geometric model of the ear. Methods: The one-dimensional mass-spring model consists of six masses (air volume of the external ear canal, eardrum, malleus, incus, stapes and cochlear fluid), plus springs and dashpots simulating the ligaments and muscles supporting. In this study, we simulated otosclerosis by an increase of 10 to 100 times of the stapedial annulus ligament stiffness and an increase by 5 times of the stapes mass. The three-dimensional model was contructed using a sample of three ear bones, malleus, incus and stapes, originated from the Institute of Biological Sciences, UFMG. The ear bones were taken to the laboratory and Ceramic Materials UFMG for conducting a test image using the X-ray SkyScan 1172. The images obtained from the three bones were imported into an image processing program, Simpleware ®, which digitally reconstructed three ear bones resulting in a three-dimensional geometric model for each of them. The geometric models of the bones were imported into Rapidform software XOR / Redesign which is capable of producing solid models with a smaller amount of data. The tympanic membrane and the ligaments were inserted along with geometric models of the bones, using SolidWorks 19.4, computer aided design software, according to the anatomical parameters found in the literature. Results: In the one-dimensional model stapes displacement were reduced at lower frequencies with increasing stiffness of the stapedial annulus ligament and reducing the displacement of the stapes in high frequencies with increased its mass. The increase of stapedial annulus ligament stiffness may be related to the initial stage of the disease, from the viewpoint audiometric, while increased bone tissue volume suggests a progression of the disease. In the three-dimensional model was possible to obtain a geometry compatible with the anatomy of the middle ear. Conclusion: The results of the one-dimensional model met the audiological findings that suggest the disease and the need for early diagnosis of the annular ligament of the stapes in order to detect as soon as the hearing loss caused by your changes. The tridimensional geometric model of the ear can be used to simulate dynamic behavior using finite-element method to understand the normal hearing, pathology and tratament.
publishDate 2013
dc.date.none.fl_str_mv 2013-04-05
2019-08-11T01:02:20Z
2019-08-11T01:02:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/PASA-9BLGNZ
url http://hdl.handle.net/1843/PASA-9BLGNZ
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
UFMG
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
UFMG
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
_version_ 1816829882152255488