Might anxiety disorders promote head and neck cancer development?

Detalhes bibliográficos
Autor(a) principal: Marcela Gonçalvesde Souza
Data de Publicação: 2020
Outros Autores: Emisael Stênio Batista Gomes, Lorena Barbosa Costa, Amanda Dias Silva Andrade, Sabrina Ferreira de Jesus, Daniela Paola Santos de Paula, Rogério Gonçalves da Rocha, Sérgio Henrique Sousa Santos, Alfredo Maurício Batista de Paula, Lucyana Conceição Farias, André Luiz Sena Guimarães
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1016/j.ibror.2020.06.001
http://hdl.handle.net/1843/44946
Resumo: CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
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spelling 2022-09-06T14:09:10Z2022-09-06T14:09:10Z2020-129913https://doi.org/10.1016/j.ibror.2020.06.0012451-8301http://hdl.handle.net/1843/44946CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorCancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an applied animal basic study and a retrospective diagnostic case and control study in patients was performed. As a result, we obtained that stress reduced the locomotor activity of the animals in the group stress and stress + 4NqO (p < 0.0001). The stress showed no influence on the progression of neoplasia in mice. In the same way, the case group did not present differences in anxiety scores in comparison to control. Moreover, no association between HNSCC staging and anxiety scores was observed. In conclusion, our in vivo findings in humans and animals have shown that there is no relationship between AD and oral squamous cell carcinoma.engUniversidade Federal de Minas GeraisUFMGBrasilICA - INSTITUTO DE CIÊNCIAS AGRÁRIASIBRO ReportsTranstornos da ansiedadeCabeça - CâncerPescoço - CâncerCarcinoma de células escamosasTumoresMight anxiety disorders promote head and neck cancer development?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.sciencedirect.com/science/article/pii/S2451830120300169Marcela Gonçalvesde SouzaEmisael Stênio Batista GomesLorena Barbosa CostaAmanda Dias Silva AndradeSabrina Ferreira de JesusDaniela Paola Santos de PaulaRogério Gonçalves da RochaSérgio Henrique Sousa SantosAlfredo Maurício Batista de PaulaLucyana Conceição FariasAndré Luiz Sena Guimarãesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/44946/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALMight anxiety disorders promote head and neck cancer development.pdfMight anxiety disorders promote head and neck cancer development.pdfapplication/pdf896535https://repositorio.ufmg.br/bitstream/1843/44946/2/Might%20anxiety%20disorders%20promote%20head%20and%20neck%20cancer%20development.pdfe6c7fccb535deafc76a3097fd607d464MD521843/449462022-09-06 11:09:10.429oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2022-09-06T14:09:10Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Might anxiety disorders promote head and neck cancer development?
title Might anxiety disorders promote head and neck cancer development?
spellingShingle Might anxiety disorders promote head and neck cancer development?
Marcela Gonçalvesde Souza
Transtornos da ansiedade
Cabeça - Câncer
Pescoço - Câncer
Carcinoma de células escamosas
Tumores
title_short Might anxiety disorders promote head and neck cancer development?
title_full Might anxiety disorders promote head and neck cancer development?
title_fullStr Might anxiety disorders promote head and neck cancer development?
title_full_unstemmed Might anxiety disorders promote head and neck cancer development?
title_sort Might anxiety disorders promote head and neck cancer development?
author Marcela Gonçalvesde Souza
author_facet Marcela Gonçalvesde Souza
Emisael Stênio Batista Gomes
Lorena Barbosa Costa
Amanda Dias Silva Andrade
Sabrina Ferreira de Jesus
Daniela Paola Santos de Paula
Rogério Gonçalves da Rocha
Sérgio Henrique Sousa Santos
Alfredo Maurício Batista de Paula
Lucyana Conceição Farias
André Luiz Sena Guimarães
author_role author
author2 Emisael Stênio Batista Gomes
Lorena Barbosa Costa
Amanda Dias Silva Andrade
Sabrina Ferreira de Jesus
Daniela Paola Santos de Paula
Rogério Gonçalves da Rocha
Sérgio Henrique Sousa Santos
Alfredo Maurício Batista de Paula
Lucyana Conceição Farias
André Luiz Sena Guimarães
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Marcela Gonçalvesde Souza
Emisael Stênio Batista Gomes
Lorena Barbosa Costa
Amanda Dias Silva Andrade
Sabrina Ferreira de Jesus
Daniela Paola Santos de Paula
Rogério Gonçalves da Rocha
Sérgio Henrique Sousa Santos
Alfredo Maurício Batista de Paula
Lucyana Conceição Farias
André Luiz Sena Guimarães
dc.subject.other.pt_BR.fl_str_mv Transtornos da ansiedade
Cabeça - Câncer
Pescoço - Câncer
Carcinoma de células escamosas
Tumores
topic Transtornos da ansiedade
Cabeça - Câncer
Pescoço - Câncer
Carcinoma de células escamosas
Tumores
description CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
publishDate 2020
dc.date.issued.fl_str_mv 2020-12
dc.date.accessioned.fl_str_mv 2022-09-06T14:09:10Z
dc.date.available.fl_str_mv 2022-09-06T14:09:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/44946
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1016/j.ibror.2020.06.001
dc.identifier.issn.pt_BR.fl_str_mv 2451-8301
url https://doi.org/10.1016/j.ibror.2020.06.001
http://hdl.handle.net/1843/44946
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dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
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dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
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