Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | http://hdl.handle.net/1843/59938 |
Resumo: | Bariatric surgery (BS) is the most successful method for weight loss in patients with grade III obesity and morbidities. However, patients undergoing BC often do not reach the recommended protein intake. Thus, protein supplements could minimize the loss of muscle mass by preventing protein malnutrition. Whey protein has high biological value, with high content of branched-chain amino acids that stimulate protein synthesis and reduce the loss of muscle mass observed in hypocaloric diets. Thus, whey protein would contribute to maintain body composition and prevent muscle loss. Our aim was to evaluate the effect of whey protein supplementation for 8 weeks in female patients in the late postoperative period of BS, regarding nutritional, metabolic and inflammatory status. After the eight weeks of experiment, there was an increase in lean mass, muscle thickness and a reduction in fat mass and fat percentage in the Whey group compared to the initial time, a result not observed in the control group. There was no difference in biochemical parameters, except for the increase in fasting blood glucose in the Malto group, which did not occur in the Whey group. In addition, there was a reduction in inflammation in the protein-supplemented group compared to the initial time. No differences were observed in handgrip strength and gait speed in the groups, as well as in energy expenditure in both groups. We conclude that whey protein supplementation can reduce fat-free mass loss and increase body fat mass regardless of changes in BMI evolution in the late postoperative period of bariatric surgery. In addition, our findings suggest that isolated milk protein supplementation can bring benefits in reducing inflammation, in addition to contributing to the maintenance of a healthy diet. |
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Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátricacirurgia bariátricawhey proteinmassa magramassa gordainflamaçãoBioquímica e imunologiaCirurgia BariátricaEstado NutricionalSuplementos NutricionaisProteinasMetabolismoInflamaçãoBariatric surgery (BS) is the most successful method for weight loss in patients with grade III obesity and morbidities. However, patients undergoing BC often do not reach the recommended protein intake. Thus, protein supplements could minimize the loss of muscle mass by preventing protein malnutrition. Whey protein has high biological value, with high content of branched-chain amino acids that stimulate protein synthesis and reduce the loss of muscle mass observed in hypocaloric diets. Thus, whey protein would contribute to maintain body composition and prevent muscle loss. Our aim was to evaluate the effect of whey protein supplementation for 8 weeks in female patients in the late postoperative period of BS, regarding nutritional, metabolic and inflammatory status. After the eight weeks of experiment, there was an increase in lean mass, muscle thickness and a reduction in fat mass and fat percentage in the Whey group compared to the initial time, a result not observed in the control group. There was no difference in biochemical parameters, except for the increase in fasting blood glucose in the Malto group, which did not occur in the Whey group. In addition, there was a reduction in inflammation in the protein-supplemented group compared to the initial time. No differences were observed in handgrip strength and gait speed in the groups, as well as in energy expenditure in both groups. We conclude that whey protein supplementation can reduce fat-free mass loss and increase body fat mass regardless of changes in BMI evolution in the late postoperative period of bariatric surgery. In addition, our findings suggest that isolated milk protein supplementation can bring benefits in reducing inflammation, in addition to contributing to the maintenance of a healthy diet.Pacientes submetidos à cirurgia bariátrica (CB) geralmente não atingem a recomendação de ingestão de proteínas, levando a perda de massa muscular. Assim, suplementos proteicos poderiam minimizar a perda e melhorar a composição corporal. Nosso objetivo foi avaliar o efeito da suplementação de whey protein por 8 semanas em mulheres no pós-operatório tardio de CB, quanto ao estado nutricional, metabólico e inflamatório. 24 mulheres foram suplementadas com 30g de whey protein por oito semanas em um estudo duplo-cego, controlado por placebo e não randomizado. Composição corporal, consumo alimentar, gasto energético, exames bioquímicos, espessura muscular, velocidade da marcha foram avaliados antes, durante e ao final do estudo. Observou-se aumento da massa magra, espessura muscular e redução da massa gorda e do percentual de gordura no grupo Whey, resultado não observado no grupo controle. Não houve diferença nos parâmetros bioquímicos, exceto pelo aumento da glicemia de jejum no grupo Malto, o que não ocorreu no grupo Whey. Houve redução da inflamação no grupo suplementado com a proteína em relação ao tempo inicial. Não houve alteração na força de preensão palmar e velocidade da marcha, bem como no gasto energético em ambos os grupos. Concluímos que a suplementação com whey protein pode reduzir a perda de massa livre de gordura e aumentar a massa gorda corporal independentemente das mudanças na evolução do IMC no pós-operatório tardio da cirurgia bariátrica. Além disso, nossos achados sugerem que a suplementação da proteína isolada do leite pode melhorar parâmetros inflamatórios e contribuir na manutenção de uma dieta saudável.FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisUniversidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMGJacqueline Isaura Alvarez Leitehttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4723009A8&tokenCaptchar=03AFcWeA52IJYM-E65ezSQUwHLgvthXoFr-VzR-JU-O1jqT9QXl5BJT_-qnk8Q95DqPuBCd-xcYDKefNk-qjekiFfu10G_qhbiLqye3JSeQdpoRbAX_CEuob-ROmdPQ60A5oOCLvW4GQv4DmweAcB_AXGwB1eZZZenu8msH9VVdZoBhj827xvh7wgvOZG_B18DeuChSvXE40RrxlVkkQUMp7SKw2qFylFqs4MCEextXGP-60DLSaEA9kmETDl0WC1bE2oCB_BoSYaxZqo_FeN4kOxlTlaPTZQNIRaHeu1w2YA3IT_dIUuv7I8mir-KQZ7LuRLCw3Km9ayJut4uxY8UURuHZro8s7IfiKeC3C4tx2rTTdZqjGgkb53rr_74SNoesGv5ncJXvWvVi981F-kp_Egl1ZNfCW3SD8dndz9QvphvfB_qVWZcSBN-h7eQLkLeUfQsQBEcQgfWRryOjWY2a82CTm7vd1iWlRzL_bV0H1pbRff8slQVnK5Z5vq1YIAKp1sh8-gPFq7bnD6HgAQf0nbsNubeTYV-NGoAdEmVS1iin4Xf5AkNSenGKRjMMWx_5UUrqYWnPv5WHirla Karen Fialho Henriques2023-10-24T16:06:02Z2023-10-24T16:06:02Z2023-09-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdfhttp://hdl.handle.net/1843/59938porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2023-10-24T16:06:02Zoai:repositorio.ufmg.br:1843/59938Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2023-10-24T16:06:02Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
title |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
spellingShingle |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica Hirla Karen Fialho Henriques cirurgia bariátrica whey protein massa magra massa gorda inflamação Bioquímica e imunologia Cirurgia Bariátrica Estado Nutricional Suplementos Nutricionais Proteinas Metabolismo Inflamação |
title_short |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
title_full |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
title_fullStr |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
title_full_unstemmed |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
title_sort |
Efeito da suplementação de proteína na composição corporal, gasto energético e parâmetros bioquímicos de pacientes submetidos à cirurgia bariátrica |
author |
Hirla Karen Fialho Henriques |
author_facet |
Hirla Karen Fialho Henriques |
author_role |
author |
dc.contributor.none.fl_str_mv |
Jacqueline Isaura Alvarez Leite http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4723009A8&tokenCaptchar=03AFcWeA52IJYM-E65ezSQUwHLgvthXoFr-VzR-JU-O1jqT9QXl5BJT_-qnk8Q95DqPuBCd-xcYDKefNk-qjekiFfu10G_qhbiLqye3JSeQdpoRbAX_CEuob-ROmdPQ60A5oOCLvW4GQv4DmweAcB_AXGwB1eZZZenu8msH9VVdZoBhj827xvh7wgvOZG_B18DeuChSvXE40RrxlVkkQUMp7SKw2qFylFqs4MCEextXGP-60DLSaEA9kmETDl0WC1bE2oCB_BoSYaxZqo_FeN4kOxlTlaPTZQNIRaHeu1w2YA3IT_dIUuv7I8mir-KQZ7LuRLCw3Km9ayJut4uxY8UURuHZro8s7IfiKeC3C4tx2rTTdZqjGgkb53rr_74SNoesGv5ncJXvWvVi981F-kp_Egl1ZNfCW3SD8dndz9QvphvfB_qVWZcSBN-h7eQLkLeUfQsQBEcQgfWRryOjWY2a82CTm7vd1iWlRzL_bV0H1pbRff8slQVnK5Z5vq1YIAKp1sh8-gPFq7bnD6HgAQf0nbsNubeTYV-NGoAdEmVS1iin4Xf5AkNSenGKRjMMWx_5UUrqYWnPv5W |
dc.contributor.author.fl_str_mv |
Hirla Karen Fialho Henriques |
dc.subject.por.fl_str_mv |
cirurgia bariátrica whey protein massa magra massa gorda inflamação Bioquímica e imunologia Cirurgia Bariátrica Estado Nutricional Suplementos Nutricionais Proteinas Metabolismo Inflamação |
topic |
cirurgia bariátrica whey protein massa magra massa gorda inflamação Bioquímica e imunologia Cirurgia Bariátrica Estado Nutricional Suplementos Nutricionais Proteinas Metabolismo Inflamação |
description |
Bariatric surgery (BS) is the most successful method for weight loss in patients with grade III obesity and morbidities. However, patients undergoing BC often do not reach the recommended protein intake. Thus, protein supplements could minimize the loss of muscle mass by preventing protein malnutrition. Whey protein has high biological value, with high content of branched-chain amino acids that stimulate protein synthesis and reduce the loss of muscle mass observed in hypocaloric diets. Thus, whey protein would contribute to maintain body composition and prevent muscle loss. Our aim was to evaluate the effect of whey protein supplementation for 8 weeks in female patients in the late postoperative period of BS, regarding nutritional, metabolic and inflammatory status. After the eight weeks of experiment, there was an increase in lean mass, muscle thickness and a reduction in fat mass and fat percentage in the Whey group compared to the initial time, a result not observed in the control group. There was no difference in biochemical parameters, except for the increase in fasting blood glucose in the Malto group, which did not occur in the Whey group. In addition, there was a reduction in inflammation in the protein-supplemented group compared to the initial time. No differences were observed in handgrip strength and gait speed in the groups, as well as in energy expenditure in both groups. We conclude that whey protein supplementation can reduce fat-free mass loss and increase body fat mass regardless of changes in BMI evolution in the late postoperative period of bariatric surgery. In addition, our findings suggest that isolated milk protein supplementation can bring benefits in reducing inflammation, in addition to contributing to the maintenance of a healthy diet. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-10-24T16:06:02Z 2023-10-24T16:06:02Z 2023-09-12 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/59938 |
url |
http://hdl.handle.net/1843/59938 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais Brasil ICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIA Programa de Pós-Graduação em Bioquímica e Imunologia UFMG |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais Brasil ICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIA Programa de Pós-Graduação em Bioquímica e Imunologia UFMG |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Repositório Institucional da UFMG |
collection |
Repositório Institucional da UFMG |
repository.name.fl_str_mv |
Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
repositorio@ufmg.br |
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1823248325593268224 |