Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMG |
Texto Completo: | http://hdl.handle.net/1843/40907 |
Resumo: | Purpose: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. Methods: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws. Results: Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target: non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups. Conclusion: Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT. |
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2022-04-07T22:57:50Z2022-04-07T22:57:50Z2018-01331142110.1590/s0102-8650201800100000021678-2674http://hdl.handle.net/1843/40907Purpose: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. Methods: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws. Results: Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target: non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups. Conclusion: Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT.engUniversidade Federal de Minas GeraisUFMGBrasilFAR - DEPARTAMENTO DE ALIMENTOSFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASMED - DEPARTAMENTO DE APARELHO LOCOMOTORMED - DEPARTAMENTO DE CIRURGIAActa Cirúrgica BrasileiraBiomateriaisInfecções periprotéticasCeftizoxima-99mBiocompatible materialsRadionuclide imagingProsthesis-related infectionsRatsInfluence of biomaterials on scintigraphic diagnosis of periprosthetic infections. 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dc.title.pt_BR.fl_str_mv |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
title |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
spellingShingle |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model Luiz Eduardo Moreira Teixeira Biocompatible materials Radionuclide imaging Prosthesis-related infections Rats Biomateriais Infecções periprotéticas Ceftizoxima-99m |
title_short |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
title_full |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
title_fullStr |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
title_full_unstemmed |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
title_sort |
Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model |
author |
Luiz Eduardo Moreira Teixeira |
author_facet |
Luiz Eduardo Moreira Teixeira Bruno Jannotti Pádua André Moreira Castilho Ivana Duval de Araújo Marco Antônio Percope de Andrade Valbert Nascimento Cardoso Simone Odília Antunes Fernandes Jefferson Soares Leal Isabella Kuniko Takenaka |
author_role |
author |
author2 |
Bruno Jannotti Pádua André Moreira Castilho Ivana Duval de Araújo Marco Antônio Percope de Andrade Valbert Nascimento Cardoso Simone Odília Antunes Fernandes Jefferson Soares Leal Isabella Kuniko Takenaka |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Luiz Eduardo Moreira Teixeira Bruno Jannotti Pádua André Moreira Castilho Ivana Duval de Araújo Marco Antônio Percope de Andrade Valbert Nascimento Cardoso Simone Odília Antunes Fernandes Jefferson Soares Leal Isabella Kuniko Takenaka |
dc.subject.por.fl_str_mv |
Biocompatible materials Radionuclide imaging Prosthesis-related infections Rats |
topic |
Biocompatible materials Radionuclide imaging Prosthesis-related infections Rats Biomateriais Infecções periprotéticas Ceftizoxima-99m |
dc.subject.other.pt_BR.fl_str_mv |
Biomateriais Infecções periprotéticas Ceftizoxima-99m |
description |
Purpose: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. Methods: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws. Results: Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target: non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups. Conclusion: Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-01 |
dc.date.accessioned.fl_str_mv |
2022-04-07T22:57:50Z |
dc.date.available.fl_str_mv |
2022-04-07T22:57:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1843/40907 |
dc.identifier.doi.pt_BR.fl_str_mv |
10.1590/s0102-865020180010000002 |
dc.identifier.issn.pt_BR.fl_str_mv |
1678-2674 |
identifier_str_mv |
10.1590/s0102-865020180010000002 1678-2674 |
url |
http://hdl.handle.net/1843/40907 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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Acta Cirúrgica Brasileira |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
dc.publisher.initials.fl_str_mv |
UFMG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
FAR - DEPARTAMENTO DE ALIMENTOS FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS MED - DEPARTAMENTO DE APARELHO LOCOMOTOR MED - DEPARTAMENTO DE CIRURGIA |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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Universidade Federal de Minas Gerais (UFMG) |
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UFMG |
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