ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO

Detalhes bibliográficos
Autor(a) principal: GABRIELA DE OLIVEIRA BLANCO
Data de Publicação: 2024
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFMS
Texto Completo: https://repositorio.ufms.br/handle/123456789/9464
Resumo: Pericoronitis is characterized by inflammation of the soft tissues associated with the crown of a partially erupted tooth. Conventional treatment is based on local measures to control the inflammatory and infectious process, such as cleaning and irrigation of the region with antimicrobial solutions, such as polyvinylpyrrolidone-iodine (PVPI). The aim of this study was to evaluate two adjuvant protocols in the treatment of pericoronitis, using irrigation of the infected site with polyvinylpyrrolidone-iodine and antimicrobial photodynamic therapy in patients treated at the School of Dentistry of the Federal University of Mato Grosso do Sul. Thirty-four participants were selected, randomly separated and allocated into three groups, where they received the protocol with irrigation of 10% PVPI, aPDT or saline 0.9%, all associated with analgesia with dipyrone sodium 500 mg/ml, every 6 hours, for two days, and mouthwash with chlorhexidine digluconate 0.12%, 10 ml, every 12 hours, for 7 days, 30 minutes after tooth brushing. Patients were reevaluated after 48 hours (T1) and 7 days (T2) of the intervention to collect data on the remission of signs and symptoms. There was no statistically significant difference in the comparison between the protocols regarding pain; however, all showed a significant reduction in pain levels. The measurement of CLO-AM edema (lateral corner of the eye to the angle of the mandible) was significantly lower at moments T1 and T2 in the group that received aPDT and in the control group when compared to T0 (initial moment, immediately before the protocols were performed). The measurement of T-CL edema (tragus to the labial commissure) showed a significant reduction at moments T1 and T2, regardless of the protocol used, in relation to T0. The measurement of T-S edema (tragus to symphysis) of the participants who received PVPI and aPDT was significantly lower at moments T1 and T2 when compared to T0. It can be concluded that both irrigation of the infected site with serum or PVPI, as well as the performance of aPDT, associated with drug therapy, were effective in reducing the pain levels of the participants evaluated. Regarding edema, the group that received aPDT had a significant decrease in all measures evaluated (CLO-AM, T-CL and T-S).
id UFMS_28f1b95338899f36595c2bbecf09787d
oai_identifier_str oai:repositorio.ufms.br:123456789/9464
network_acronym_str UFMS
network_name_str Repositório Institucional da UFMS
repository_id_str 2124
spelling 2024-09-26T12:03:16Z2024-09-26T12:03:16Z2024https://repositorio.ufms.br/handle/123456789/9464Pericoronitis is characterized by inflammation of the soft tissues associated with the crown of a partially erupted tooth. Conventional treatment is based on local measures to control the inflammatory and infectious process, such as cleaning and irrigation of the region with antimicrobial solutions, such as polyvinylpyrrolidone-iodine (PVPI). The aim of this study was to evaluate two adjuvant protocols in the treatment of pericoronitis, using irrigation of the infected site with polyvinylpyrrolidone-iodine and antimicrobial photodynamic therapy in patients treated at the School of Dentistry of the Federal University of Mato Grosso do Sul. Thirty-four participants were selected, randomly separated and allocated into three groups, where they received the protocol with irrigation of 10% PVPI, aPDT or saline 0.9%, all associated with analgesia with dipyrone sodium 500 mg/ml, every 6 hours, for two days, and mouthwash with chlorhexidine digluconate 0.12%, 10 ml, every 12 hours, for 7 days, 30 minutes after tooth brushing. Patients were reevaluated after 48 hours (T1) and 7 days (T2) of the intervention to collect data on the remission of signs and symptoms. There was no statistically significant difference in the comparison between the protocols regarding pain; however, all showed a significant reduction in pain levels. The measurement of CLO-AM edema (lateral corner of the eye to the angle of the mandible) was significantly lower at moments T1 and T2 in the group that received aPDT and in the control group when compared to T0 (initial moment, immediately before the protocols were performed). The measurement of T-CL edema (tragus to the labial commissure) showed a significant reduction at moments T1 and T2, regardless of the protocol used, in relation to T0. The measurement of T-S edema (tragus to symphysis) of the participants who received PVPI and aPDT was significantly lower at moments T1 and T2 when compared to T0. It can be concluded that both irrigation of the infected site with serum or PVPI, as well as the performance of aPDT, associated with drug therapy, were effective in reducing the pain levels of the participants evaluated. Regarding edema, the group that received aPDT had a significant decrease in all measures evaluated (CLO-AM, T-CL and T-S).A pericoronarite é caracterizada pela inflamação dos tecidos moles associados à coroa de um dente parcialmente erupcionado. O tratamento convencional é baseado em medidas locais de controle do processo inflamatório e infeccioso, como limpeza e irrigação da região com soluções antimicrobianas, como o polivinilpirrolidona-iodo (PVPI). O objetivo desse estudo foi avaliar dois protocolos adjuvantes no tratamento de pericoronarite, utilizando a irrigação do sítio infectado com polivinilpirrolidona-iodo e a terapia fotodinâmica antimicrobiana em pacientes atendidos na Faculdade de Odontologia da Universidade Federal de Mato Grosso do Sul. Trinta e quatro participantes foram selecionados, separados de forma randomizada e alocados em três grupos, onde receberam o protocolo com irrigação de PVPI a 10%, aPDT ou soro fisiologógico 0,9%, todos associados à analgesia com dipirona sódica 500 mg/ml, a cada 06 horas, durante dois dias, e bochecho com digluconato de clorexidina 0,12%, 10 ml, a cada 12 horas, durante 07 dias, 30 minutos após a escovação dental. Os pacientes foram reavaliados após 48 horas (T1) e 07 dias (T2) da intervenção para coleta de dados quanto à remissão de sinais e sintomas. Não houve diferença estatística significativa na comparação entre os protocolos com relação à dor, no entanto, todos apresentaram redução significativa dos níveis dolorosos. A medida do edema CLO-AM (canto lateral do olho ao ângulo da mandíbula) foi significativamente menor nos momentos T1 e T2 no grupo recebeu aPDT e no grupo controle quando comparados com T0 (momento inicial, imediatamente antes da realização dos protocolos). Já a medida do edema T-CL (trágus à comissura labial) teve redução significativa nos momentos T1 e T2, independente do protocolo utilizado, em relação ao T0. A medida do edema T-S (trágus à sínfise) dos participantes que receberam PVPI e aPDT, foi significativamente menor nos momentos T1 e T2 quando comparadas ao T0. Pode-se concluir que tanto a irrigação do sítio infectado com soro ou PVPI, como a realização da aPDT, associados a terapia medicamentosa, foram eficazes na diminuição dos níveis de dor dos participantes avaliados. No que diz respeito ao edema, o grupo que recebeu a aPDT teve diminuição significativa em todas as medidas avaliadas (CLO-AM, T-CL e T-S).Fundação Universidade Federal de Mato Grosso do SulUFMSBrasilPERICORONARITE, ODONTOLOGIA, ENSAIO CLÍNICOANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADOinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisAlbert Schiaveto de SouzaGABRIELA DE OLIVEIRA BLANCOinfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFMSinstname:Universidade Federal de Mato Grosso do Sul (UFMS)instacron:UFMSORIGINALDissertação Gabriela Final.pdfDissertação Gabriela Final.pdfapplication/pdf1424780https://repositorio.ufms.br/bitstream/123456789/9464/-1/Disserta%c3%a7%c3%a3o%20Gabriela%20Final.pdf589ace89d023fd1fabe5d1e0c7fe5669MD5-1123456789/94642024-09-26 08:03:19.651oai:repositorio.ufms.br:123456789/9464Repositório InstitucionalPUBhttps://repositorio.ufms.br/oai/requestri.prograd@ufms.bropendoar:21242024-09-26T12:03:19Repositório Institucional da UFMS - Universidade Federal de Mato Grosso do Sul (UFMS)false
dc.title.pt_BR.fl_str_mv ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
title ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
spellingShingle ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
GABRIELA DE OLIVEIRA BLANCO
PERICORONARITE, ODONTOLOGIA, ENSAIO CLÍNICO
title_short ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
title_full ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
title_fullStr ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
title_full_unstemmed ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
title_sort ANÁLISE COMPARATIVA DE DOIS PROTOCOLOS ADJUVANTES NO TRATAMENTO DA PERICORONARITE: ENSAIO CLÍNICO RANDOMIZADO
author GABRIELA DE OLIVEIRA BLANCO
author_facet GABRIELA DE OLIVEIRA BLANCO
author_role author
dc.contributor.advisor1.fl_str_mv Albert Schiaveto de Souza
dc.contributor.author.fl_str_mv GABRIELA DE OLIVEIRA BLANCO
contributor_str_mv Albert Schiaveto de Souza
dc.subject.por.fl_str_mv PERICORONARITE, ODONTOLOGIA, ENSAIO CLÍNICO
topic PERICORONARITE, ODONTOLOGIA, ENSAIO CLÍNICO
description Pericoronitis is characterized by inflammation of the soft tissues associated with the crown of a partially erupted tooth. Conventional treatment is based on local measures to control the inflammatory and infectious process, such as cleaning and irrigation of the region with antimicrobial solutions, such as polyvinylpyrrolidone-iodine (PVPI). The aim of this study was to evaluate two adjuvant protocols in the treatment of pericoronitis, using irrigation of the infected site with polyvinylpyrrolidone-iodine and antimicrobial photodynamic therapy in patients treated at the School of Dentistry of the Federal University of Mato Grosso do Sul. Thirty-four participants were selected, randomly separated and allocated into three groups, where they received the protocol with irrigation of 10% PVPI, aPDT or saline 0.9%, all associated with analgesia with dipyrone sodium 500 mg/ml, every 6 hours, for two days, and mouthwash with chlorhexidine digluconate 0.12%, 10 ml, every 12 hours, for 7 days, 30 minutes after tooth brushing. Patients were reevaluated after 48 hours (T1) and 7 days (T2) of the intervention to collect data on the remission of signs and symptoms. There was no statistically significant difference in the comparison between the protocols regarding pain; however, all showed a significant reduction in pain levels. The measurement of CLO-AM edema (lateral corner of the eye to the angle of the mandible) was significantly lower at moments T1 and T2 in the group that received aPDT and in the control group when compared to T0 (initial moment, immediately before the protocols were performed). The measurement of T-CL edema (tragus to the labial commissure) showed a significant reduction at moments T1 and T2, regardless of the protocol used, in relation to T0. The measurement of T-S edema (tragus to symphysis) of the participants who received PVPI and aPDT was significantly lower at moments T1 and T2 when compared to T0. It can be concluded that both irrigation of the infected site with serum or PVPI, as well as the performance of aPDT, associated with drug therapy, were effective in reducing the pain levels of the participants evaluated. Regarding edema, the group that received aPDT had a significant decrease in all measures evaluated (CLO-AM, T-CL and T-S).
publishDate 2024
dc.date.accessioned.fl_str_mv 2024-09-26T12:03:16Z
dc.date.available.fl_str_mv 2024-09-26T12:03:16Z
dc.date.issued.fl_str_mv 2024
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio.ufms.br/handle/123456789/9464
url https://repositorio.ufms.br/handle/123456789/9464
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Universidade Federal de Mato Grosso do Sul
dc.publisher.initials.fl_str_mv UFMS
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv Fundação Universidade Federal de Mato Grosso do Sul
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMS
instname:Universidade Federal de Mato Grosso do Sul (UFMS)
instacron:UFMS
instname_str Universidade Federal de Mato Grosso do Sul (UFMS)
instacron_str UFMS
institution UFMS
reponame_str Repositório Institucional da UFMS
collection Repositório Institucional da UFMS
bitstream.url.fl_str_mv https://repositorio.ufms.br/bitstream/123456789/9464/-1/Disserta%c3%a7%c3%a3o%20Gabriela%20Final.pdf
bitstream.checksum.fl_str_mv 589ace89d023fd1fabe5d1e0c7fe5669
bitstream.checksumAlgorithm.fl_str_mv MD5
repository.name.fl_str_mv Repositório Institucional da UFMS - Universidade Federal de Mato Grosso do Sul (UFMS)
repository.mail.fl_str_mv ri.prograd@ufms.br
_version_ 1815447967429033984