Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos

Detalhes bibliográficos
Autor(a) principal: Humberta Correia Silva Azambuja
Data de Publicação: 2021
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFMS
Texto Completo: https://repositorio.ufms.br/handle/123456789/3704
Resumo: Influenza is a disease that affects the respiratory system and can cause more serious damage in risk groups, in which older people are inserted. In order to reduce morbidity and mortality due to the disease, a public vaccination policy was created through annual campaigns, aiming at high and homogeneous coverage rates. However, some factors may influence the adherence of older adults to the vaccine. The aim was to assess the impact of influenza vaccination on influenza morbidity and mortality in Brazil and to analyze factors related to the older population's adherence to influenza vaccine in the city of Três Lagoas - MS. All ethical issues were observed. This thesis is structured in three papers. The first aimed to analyze the impact of influenza vaccination on morbidity and mortality from influenza in the elderly from 2010 to 2019 in the regions of Brazil. It is an ecological epidemiological study with data from the Information System of the National Immunization Program, Hospital Information System, and Mortality Information System, referring to Brazil and its regions. The data included influenza vaccination coverage rates and morbidity and mortality from causes related to influenza and pneumonia in the elderly. Simple linear regression models were used. There was an increase in vaccination coverage in the period, and the goal of 80% coverage was reached in all regions since 2011. The increase in vaccination coverage was directly related to the increase in morbidity and mortality. However, it was detected that the data used to calculate vaccination coverage were out of date. The second paper aimed to identify the sociodemographic, health and knowledge variables about vaccination related to the adherence to influenza vaccine in older adults. A sociodemographic and health questionnaire and questions related to influenza vaccination were applied in n = 172 elderly people. Prevalence ratios and Bayesian learning networks were used to analyze the data. Most of the elderly were female, with a partner, between 60-69 years old, and with elementary education. The majority of them knew the National Immunization Program (PNI) and trusted it, knew that the influenza vaccine is indicated for the elderly and used to take it annually. The rate of adherence to the influenza vaccine in the previous campaign was 91.3%. Elderly people with neuropsychiatric diseases, who received the vaccine annually and who had taken it in 2018, 2016 and 2015 had a higher prevalence of adherence. The Bayesian networks showed that knowing that the PNI exists leads to trust in it, which leads to annual vaccination. The aim of the third paper was to know the reasons for elderly adherence to the influenza vaccine before and during the Covid-19 pandemic. It is a quantitative and longitudinal study. At the beginning of 2020, 86 elderly people were evaluated in person. They were questioned about adherence to the flu vaccine in 2019, and the reasons for adherence or non-adherence. The second assessment was between August and October 2020, by telephone. The questions were about vaccine adherence in 2020 and the reasons. Most of the sample were women, half had a partner and the average age was 69.1 years. Vaccine adherence in 2019 was 90.73%, with the majority taking the vaccine because they believe it really works and that it is important to get vaccinated. Among those who did not adhere, the lack of knowledge about the campaign and the fact that they did not catch the flu prevailed. In 2020, adherence was 86%, with the majority adhering due to the availability of the vaccine at the health service and the loss of the vaccine's effect after one year. The most prevalent reasons for non-adherence were the fear of leaving home due to the pandemic and the lack of professional guidance. In conclusion, maintaining high vaccination coverage can prevent the impact of influenza being even greater on morbidity and mortality in the elderly. The pandemic may have influenced influenza vaccination rates in the elderly. The promotion of influenza vaccination should disseminate knowledge about the importance of annual vaccination, in order to obtain high and homogeneous vaccine coverage.
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spelling 2021-05-20T23:41:49Z2021-09-30T19:56:14Z2021https://repositorio.ufms.br/handle/123456789/3704Influenza is a disease that affects the respiratory system and can cause more serious damage in risk groups, in which older people are inserted. In order to reduce morbidity and mortality due to the disease, a public vaccination policy was created through annual campaigns, aiming at high and homogeneous coverage rates. However, some factors may influence the adherence of older adults to the vaccine. The aim was to assess the impact of influenza vaccination on influenza morbidity and mortality in Brazil and to analyze factors related to the older population's adherence to influenza vaccine in the city of Três Lagoas - MS. All ethical issues were observed. This thesis is structured in three papers. The first aimed to analyze the impact of influenza vaccination on morbidity and mortality from influenza in the elderly from 2010 to 2019 in the regions of Brazil. It is an ecological epidemiological study with data from the Information System of the National Immunization Program, Hospital Information System, and Mortality Information System, referring to Brazil and its regions. The data included influenza vaccination coverage rates and morbidity and mortality from causes related to influenza and pneumonia in the elderly. Simple linear regression models were used. There was an increase in vaccination coverage in the period, and the goal of 80% coverage was reached in all regions since 2011. The increase in vaccination coverage was directly related to the increase in morbidity and mortality. However, it was detected that the data used to calculate vaccination coverage were out of date. The second paper aimed to identify the sociodemographic, health and knowledge variables about vaccination related to the adherence to influenza vaccine in older adults. A sociodemographic and health questionnaire and questions related to influenza vaccination were applied in n = 172 elderly people. Prevalence ratios and Bayesian learning networks were used to analyze the data. Most of the elderly were female, with a partner, between 60-69 years old, and with elementary education. The majority of them knew the National Immunization Program (PNI) and trusted it, knew that the influenza vaccine is indicated for the elderly and used to take it annually. The rate of adherence to the influenza vaccine in the previous campaign was 91.3%. Elderly people with neuropsychiatric diseases, who received the vaccine annually and who had taken it in 2018, 2016 and 2015 had a higher prevalence of adherence. The Bayesian networks showed that knowing that the PNI exists leads to trust in it, which leads to annual vaccination. The aim of the third paper was to know the reasons for elderly adherence to the influenza vaccine before and during the Covid-19 pandemic. It is a quantitative and longitudinal study. At the beginning of 2020, 86 elderly people were evaluated in person. They were questioned about adherence to the flu vaccine in 2019, and the reasons for adherence or non-adherence. The second assessment was between August and October 2020, by telephone. The questions were about vaccine adherence in 2020 and the reasons. Most of the sample were women, half had a partner and the average age was 69.1 years. Vaccine adherence in 2019 was 90.73%, with the majority taking the vaccine because they believe it really works and that it is important to get vaccinated. Among those who did not adhere, the lack of knowledge about the campaign and the fact that they did not catch the flu prevailed. In 2020, adherence was 86%, with the majority adhering due to the availability of the vaccine at the health service and the loss of the vaccine's effect after one year. The most prevalent reasons for non-adherence were the fear of leaving home due to the pandemic and the lack of professional guidance. In conclusion, maintaining high vaccination coverage can prevent the impact of influenza being even greater on morbidity and mortality in the elderly. The pandemic may have influenced influenza vaccination rates in the elderly. The promotion of influenza vaccination should disseminate knowledge about the importance of annual vaccination, in order to obtain high and homogeneous vaccine coverage.A influenza é uma doença que atinge o sistema respiratório e pode causar graves danos nos grupos de risco, nos quais o idoso está inserido. A política pública de vacinação por meio de campanhas anuais visa diminuir a morbimortalidade pela doença mediante altas e homogêneas coberturas vacinais. Diversos fatores podem influenciar a adesão dos idosos à vacina. O objetivo foi avaliar o impacto da vacinação contra a gripe na morbimortalidade por influenza no Brasil e analisar fatores relacionados à adesão da população idosa a vacina contra a influenza no município de Três Lagoas -MS. Todos os cuidados éticos foram observados. Está estruturada em três artigos. O primeiro objetivou analisar o impacto da vacinação contra gripe na morbimortalidade por influenza de idosos no período de 2010 a 2019 nas regiões do Brasil. É um estudo epidemiológico ecológico, com dados do Sistema de Informações do Programa Nacional de Imunizações, do Sistema de Informação Hospitalar e do Sistema de Informação de Mortalidade, referentes ao Brasil e regiões. Foram contempladas as taxas de cobertura vacinal contra gripe em idosos e de morbidade e mortalidade por causas relacionadas à influenza e pneumonia. Modelos de regressão linear foram utilizados. Houve um aumento da cobertura vacinal durante o período, e a meta de 80% de cobertura foi atingida em todas as regiões a partir de 2011. O aumento na cobertura vacinal teve relação direta com o aumento da morbimortalidade. Porém, detectou-se que os dados utilizados para o cálculo das coberturas vacinais estavam desatualizados. O segundo artigo objetivou identificar as variáveis sociodemográficas, de saúde e de conhecimento sobre a vacinação relacionadas à adesão da população idosa à vacina contra influenza no ano de 2019. Foi desenvolvido com n=172 idosos. Aplicou-se um questionário sociodemográfico, de saúde, e questões relacionadas à vacinação contra influenza. Utilizou-se razão de prevalência e redes bayesianas de aprendizado para analisar os dados. A maioria dos idosos era do sexo feminino, com companheiro, entre 60-69 anos, com ensino fundamental, conhecia o Programa Nacional de Imunização (PNI) e confiava nele, sabia que a vacina contra influenza é indicada para idosos e costumava tomá-la anualmente. A taxa de adesão à vacina contra influenza na campanha de 2019foi de 91,3%. Os idosos com doenças neuropsiquiátricas, que tomavam a vacina anualmente e que tinham tomado em2018, 2016 e 2015 tiveram maior prevalência de adesão. As redes bayesianas evidenciaram que saber que existe o PNI leva a confiar no mesmo, que conduz os idosos tomar a vacina anualmente. O objetivo do terceiro artigo foi compreender os motivos para adesão dos idosos à vacina contra influenza antes e durante a pandemia de Covid-19. Foi um estudo quantitativo e longitudinal. No início de 2020, 86 idosos foram avaliados presencialmente. Questionou-se sobre a adesão à vacina de gripe em 2019, e os motivos para adesão ou não adesão. A segunda avaliação foi entre agosto e outubro de 2020, pelo telefone. Questionou-se sobre a adesão à vacina em 2020 e os motivos. A maioria dos idosos era mulher, metade tinha companheiro e média de idade de 69,1 anos. A adesão vacinal em 2019 foi de 90,7%, sendo que a maioria tomou a vacina por acreditar que realmente funciona e que é importante se vacinar. Dentre os que não aderiram, prevaleceram o desconhecimento sobre a campanha e o fato de não ficar gripado. Em 2020, a adesão foi de 86%, com a maioria aderindo devido à disponibilidade da vacina no serviço de saúde e pela perda do efeito da vacina após um ano. Os motivos mais prevalentes da não adesão em 2020 foram o medo de sair de casa devido à pandemia e a falta de orientação profissional. Conclui-se que a manutenção da cobertura vacinal elevada pode prevenir que o impacto da gripe seja ainda maior na morbimortalidade em idosos. A pandemia parece ter influenciado nas taxas de vacinação contra influenza em idosos. A promoção da vacinação contra a gripe em idosos deve disseminar o conhecimento sobre a importância da vacinação anual, para se obter altas e homogêneas coberturas vacinais.Fundação Universidade Federal de Mato Grosso do SulUFMSBrasilVacinas contra InfluenzaIdosoProgramas de imunizaçãoCobertura VacinalMorbidadeRegistros de MortalidadeEnfermagem Geriátrica.Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idososinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisBruna Moretti LuchesiHumberta Correia Silva Azambujainfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFMSinstname:Universidade Federal de Mato Grosso do Sul (UFMS)instacron:UFMSTHUMBNAILDefesa_versão final 29_03.pdf.jpgDefesa_versão final 29_03.pdf.jpgGenerated Thumbnailimage/jpeg1301https://repositorio.ufms.br/bitstream/123456789/3704/3/Defesa_vers%c3%a3o%20final%2029_03.pdf.jpge2122299ca4173e7312bd211327dc8d1MD53TEXTDefesa_versão final 29_03.pdf.txtDefesa_versão final 29_03.pdf.txtExtracted texttext/plain230438https://repositorio.ufms.br/bitstream/123456789/3704/2/Defesa_vers%c3%a3o%20final%2029_03.pdf.txtb5ec5477934d4a9f29c995698c3719d5MD52ORIGINALDefesa_versão final 29_03.pdfDefesa_versão final 29_03.pdfapplication/pdf1628239https://repositorio.ufms.br/bitstream/123456789/3704/1/Defesa_vers%c3%a3o%20final%2029_03.pdf2da2292c3e1577250639866c489aff6bMD51123456789/37042021-09-30 15:56:14.466oai:repositorio.ufms.br:123456789/3704Repositório InstitucionalPUBhttps://repositorio.ufms.br/oai/requestri.prograd@ufms.bropendoar:21242021-09-30T19:56:14Repositório Institucional da UFMS - Universidade Federal de Mato Grosso do Sul (UFMS)false
dc.title.pt_BR.fl_str_mv Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
title Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
spellingShingle Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
Humberta Correia Silva Azambuja
Vacinas contra Influenza
Idoso
Programas de imunização
Cobertura Vacinal
Morbidade
Registros de Mortalidade
Enfermagem Geriátrica.
title_short Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
title_full Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
title_fullStr Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
title_full_unstemmed Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
title_sort Vacina contra Influenza: impacto da morbimortalidade e fatores relacionados à adesão em idosos
author Humberta Correia Silva Azambuja
author_facet Humberta Correia Silva Azambuja
author_role author
dc.contributor.advisor1.fl_str_mv Bruna Moretti Luchesi
dc.contributor.author.fl_str_mv Humberta Correia Silva Azambuja
contributor_str_mv Bruna Moretti Luchesi
dc.subject.por.fl_str_mv Vacinas contra Influenza
Idoso
Programas de imunização
Cobertura Vacinal
Morbidade
Registros de Mortalidade
Enfermagem Geriátrica.
topic Vacinas contra Influenza
Idoso
Programas de imunização
Cobertura Vacinal
Morbidade
Registros de Mortalidade
Enfermagem Geriátrica.
description Influenza is a disease that affects the respiratory system and can cause more serious damage in risk groups, in which older people are inserted. In order to reduce morbidity and mortality due to the disease, a public vaccination policy was created through annual campaigns, aiming at high and homogeneous coverage rates. However, some factors may influence the adherence of older adults to the vaccine. The aim was to assess the impact of influenza vaccination on influenza morbidity and mortality in Brazil and to analyze factors related to the older population's adherence to influenza vaccine in the city of Três Lagoas - MS. All ethical issues were observed. This thesis is structured in three papers. The first aimed to analyze the impact of influenza vaccination on morbidity and mortality from influenza in the elderly from 2010 to 2019 in the regions of Brazil. It is an ecological epidemiological study with data from the Information System of the National Immunization Program, Hospital Information System, and Mortality Information System, referring to Brazil and its regions. The data included influenza vaccination coverage rates and morbidity and mortality from causes related to influenza and pneumonia in the elderly. Simple linear regression models were used. There was an increase in vaccination coverage in the period, and the goal of 80% coverage was reached in all regions since 2011. The increase in vaccination coverage was directly related to the increase in morbidity and mortality. However, it was detected that the data used to calculate vaccination coverage were out of date. The second paper aimed to identify the sociodemographic, health and knowledge variables about vaccination related to the adherence to influenza vaccine in older adults. A sociodemographic and health questionnaire and questions related to influenza vaccination were applied in n = 172 elderly people. Prevalence ratios and Bayesian learning networks were used to analyze the data. Most of the elderly were female, with a partner, between 60-69 years old, and with elementary education. The majority of them knew the National Immunization Program (PNI) and trusted it, knew that the influenza vaccine is indicated for the elderly and used to take it annually. The rate of adherence to the influenza vaccine in the previous campaign was 91.3%. Elderly people with neuropsychiatric diseases, who received the vaccine annually and who had taken it in 2018, 2016 and 2015 had a higher prevalence of adherence. The Bayesian networks showed that knowing that the PNI exists leads to trust in it, which leads to annual vaccination. The aim of the third paper was to know the reasons for elderly adherence to the influenza vaccine before and during the Covid-19 pandemic. It is a quantitative and longitudinal study. At the beginning of 2020, 86 elderly people were evaluated in person. They were questioned about adherence to the flu vaccine in 2019, and the reasons for adherence or non-adherence. The second assessment was between August and October 2020, by telephone. The questions were about vaccine adherence in 2020 and the reasons. Most of the sample were women, half had a partner and the average age was 69.1 years. Vaccine adherence in 2019 was 90.73%, with the majority taking the vaccine because they believe it really works and that it is important to get vaccinated. Among those who did not adhere, the lack of knowledge about the campaign and the fact that they did not catch the flu prevailed. In 2020, adherence was 86%, with the majority adhering due to the availability of the vaccine at the health service and the loss of the vaccine's effect after one year. The most prevalent reasons for non-adherence were the fear of leaving home due to the pandemic and the lack of professional guidance. In conclusion, maintaining high vaccination coverage can prevent the impact of influenza being even greater on morbidity and mortality in the elderly. The pandemic may have influenced influenza vaccination rates in the elderly. The promotion of influenza vaccination should disseminate knowledge about the importance of annual vaccination, in order to obtain high and homogeneous vaccine coverage.
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