Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMS |
Texto Completo: | https://repositorio.ufms.br/handle/123456789/132 |
Resumo: | The incidence of Candida bloodstream infection has increased over the past years. In the Center-West region of Brazil, data on candidemia are scarce. This paper reports a retrospective analysis of 96 cases of Candida bloodstream infection at a Brazilian tertiary-care teaching hospital in the state of Mato Grosso do Sul, from January 1998 to December 2006. Demographic, clinical and laboratory data were collected from medical records and from the hospital's laboratory database. Patients' ages ranged from three days to 92 years, with 53 (55.2%) adults and 43 (44.8%) children. Of the latter, 25 (58.1%) were newborns. The risk conditions most often found were: long period of hospitalization, utilization of venous central catheter, and previous use of antibiotics. Fifty-eight (60.4%) patients died during the hospitalization period and eight (13.7%) of them died 30 days after the diagnosis of candidemia. Candida albicans (45.8%) was the most prevalent species, followed by C. parapsilosis (34.4%), C. tropicalis (14.6%) and C. glabrata (5.2%). This is the first report of Candida bloodstream infection in the state of Mato Grosso do Sul and it highlights the importance of considering the possibility of invasive Candida infection in patients exposed to risk factors, particularly among neonates and the elderly. |
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2011-07-12T19:53:46Z2021-09-30T19:56:50Z2008CHANG, Marilene Rodrigues et al . Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil. Rev. Inst. Med. trop. S. Paulo, São Paulo, v. 50, n. 5, Oct. 2008 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652008000500003&lng=en&nrm=iso>. access on 12 July 2011. doi: 10.1590/S0036-46652008000500003.https://repositorio.ufms.br/handle/123456789/13210.1590/S0036-46652008000500003The incidence of Candida bloodstream infection has increased over the past years. In the Center-West region of Brazil, data on candidemia are scarce. This paper reports a retrospective analysis of 96 cases of Candida bloodstream infection at a Brazilian tertiary-care teaching hospital in the state of Mato Grosso do Sul, from January 1998 to December 2006. Demographic, clinical and laboratory data were collected from medical records and from the hospital's laboratory database. Patients' ages ranged from three days to 92 years, with 53 (55.2%) adults and 43 (44.8%) children. Of the latter, 25 (58.1%) were newborns. The risk conditions most often found were: long period of hospitalization, utilization of venous central catheter, and previous use of antibiotics. Fifty-eight (60.4%) patients died during the hospitalization period and eight (13.7%) of them died 30 days after the diagnosis of candidemia. Candida albicans (45.8%) was the most prevalent species, followed by C. parapsilosis (34.4%), C. tropicalis (14.6%) and C. glabrata (5.2%). This is the first report of Candida bloodstream infection in the state of Mato Grosso do Sul and it highlights the importance of considering the possibility of invasive Candida infection in patients exposed to risk factors, particularly among neonates and the elderly.A incidência de infecções na corrente sangüínea causada por Candida spp. tem aumentado nos últimos anos. Na região Centro-Oeste do Brasil, os dados sobre candidemia são escassos. Realizamos uma análise retrospectiva de casos de infecção na corrente sangüínea por Candida em um hospital terciário de ensino de Mato Grosso do Sul. Noventa e seis episódios diagnosticados de janeiro de 1998 a dezembro de 2006 foram incluídos no estudo. Os dados demográficos e clínicos foram obtidos de prontuários; os dados laboratoriais provieram de registros do laboratório hospitalar. Dos pacientes, 43 (44,8%) eram crianças e 53 (55,2%) adultos, com idades variando de três dias a 92 anos. Das crianças, 25 (58,1%) eram recém-nascidas. As condições de risco mais encontradas foram: prolongado tempo de internação, uso de cateter venoso central e uso prévio de antibióticos. Cinqüenta e oito (60,4%) pacientes foram a óbito durante a hospitalização e oito (13,7%) deles foram a óbito 30 dias após o diagnóstico de candidemia. Candida albicans (45,8%) foi a espécie mais prevalente seguida por C. parapsilosis (34,4%), C. tropicalis (14,6%) e C. glabrata (5,2%). Esta é a primeira descrição de infecção na corrente sangüínea por espécies de Candida em Mato Grosso do Sul, confirmando a importância da suspeita clínica de infecções invasivas por tais microrganismos na evolução de pacientes expostos a fatores de risco, principalmente no caso de idosos e neonatos.engRevista do Instituto de Medicina Tropical de São PauloCandidemiaFatores de RiscoBloodstream infectionCandida sppCandida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, BrazilInfecção na corrente sangüínea por Candida spp. dados de um hospital universitário em Mato Grosso do Sul, Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleChang, Marilene RodriguesCorreia, Flávia PatussiCosta, Leonora CorreaXavier, Paula Cristhina NizPalhares, Durval BatistaTaira, Deborah LedesmaPaniago, Anamaria Mello MirandaPontes, Elenir Rose Jardim CuryMachado, Vanessa Escobarinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMSinstname:Universidade Federal de Mato Grosso do Sul (UFMS)instacron:UFMSTHUMBNAILCandida bloodstream infection.pdf.jpgCandida bloodstream infection.pdf.jpgGenerated Thumbnailimage/jpeg1625https://repositorio.ufms.br/bitstream/123456789/132/4/Candida%20bloodstream%20infection.pdf.jpge13d5ce03e7d3bce43cd53dd76fb4743MD54ORIGINALCandida bloodstream infection.pdfCandida bloodstream infection.pdfapplication/pdf127361https://repositorio.ufms.br/bitstream/123456789/132/1/Candida%20bloodstream%20infection.pdfe96691017893294cbcbea945d95dd768MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufms.br/bitstream/123456789/132/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTCandida bloodstream infection.pdf.txtCandida bloodstream infection.pdf.txtExtracted texttext/plain20210https://repositorio.ufms.br/bitstream/123456789/132/3/Candida%20bloodstream%20infection.pdf.txtfb8bb9faec727b3d49e0432c03533f6bMD53123456789/1322021-09-30 15:56:50.139oai:repositorio.ufms.br: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Repositório InstitucionalPUBhttps://repositorio.ufms.br/oai/requestri.prograd@ufms.bropendoar:21242021-09-30T19:56:50Repositório Institucional da UFMS - Universidade Federal de Mato Grosso do Sul (UFMS)false |
dc.title.pt_BR.fl_str_mv |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
dc.title.alternative.pt_BR.fl_str_mv |
Infecção na corrente sangüínea por Candida spp. dados de um hospital universitário em Mato Grosso do Sul, Brasil |
title |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
spellingShingle |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil Chang, Marilene Rodrigues Candidemia Fatores de Risco Bloodstream infection Candida spp |
title_short |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
title_full |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
title_fullStr |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
title_full_unstemmed |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
title_sort |
Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil |
author |
Chang, Marilene Rodrigues |
author_facet |
Chang, Marilene Rodrigues Correia, Flávia Patussi Costa, Leonora Correa Xavier, Paula Cristhina Niz Palhares, Durval Batista Taira, Deborah Ledesma Paniago, Anamaria Mello Miranda Pontes, Elenir Rose Jardim Cury Machado, Vanessa Escobar |
author_role |
author |
author2 |
Correia, Flávia Patussi Costa, Leonora Correa Xavier, Paula Cristhina Niz Palhares, Durval Batista Taira, Deborah Ledesma Paniago, Anamaria Mello Miranda Pontes, Elenir Rose Jardim Cury Machado, Vanessa Escobar |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Chang, Marilene Rodrigues Correia, Flávia Patussi Costa, Leonora Correa Xavier, Paula Cristhina Niz Palhares, Durval Batista Taira, Deborah Ledesma Paniago, Anamaria Mello Miranda Pontes, Elenir Rose Jardim Cury Machado, Vanessa Escobar |
dc.subject.por.fl_str_mv |
Candidemia Fatores de Risco Bloodstream infection Candida spp |
topic |
Candidemia Fatores de Risco Bloodstream infection Candida spp |
description |
The incidence of Candida bloodstream infection has increased over the past years. In the Center-West region of Brazil, data on candidemia are scarce. This paper reports a retrospective analysis of 96 cases of Candida bloodstream infection at a Brazilian tertiary-care teaching hospital in the state of Mato Grosso do Sul, from January 1998 to December 2006. Demographic, clinical and laboratory data were collected from medical records and from the hospital's laboratory database. Patients' ages ranged from three days to 92 years, with 53 (55.2%) adults and 43 (44.8%) children. Of the latter, 25 (58.1%) were newborns. The risk conditions most often found were: long period of hospitalization, utilization of venous central catheter, and previous use of antibiotics. Fifty-eight (60.4%) patients died during the hospitalization period and eight (13.7%) of them died 30 days after the diagnosis of candidemia. Candida albicans (45.8%) was the most prevalent species, followed by C. parapsilosis (34.4%), C. tropicalis (14.6%) and C. glabrata (5.2%). This is the first report of Candida bloodstream infection in the state of Mato Grosso do Sul and it highlights the importance of considering the possibility of invasive Candida infection in patients exposed to risk factors, particularly among neonates and the elderly. |
publishDate |
2008 |
dc.date.issued.fl_str_mv |
2008 |
dc.date.accessioned.fl_str_mv |
2011-07-12T19:53:46Z |
dc.date.available.fl_str_mv |
2021-09-30T19:56:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CHANG, Marilene Rodrigues et al . Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil. Rev. Inst. Med. trop. S. Paulo, São Paulo, v. 50, n. 5, Oct. 2008 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652008000500003&lng=en&nrm=iso>. access on 12 July 2011. doi: 10.1590/S0036-46652008000500003. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufms.br/handle/123456789/132 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0036-46652008000500003 |
identifier_str_mv |
CHANG, Marilene Rodrigues et al . Candida bloodstream infection: data from a teaching hospital in Mato Grosso do Sul, Brazil. Rev. Inst. Med. trop. S. Paulo, São Paulo, v. 50, n. 5, Oct. 2008 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652008000500003&lng=en&nrm=iso>. access on 12 July 2011. doi: 10.1590/S0036-46652008000500003. 10.1590/S0036-46652008000500003 |
url |
https://repositorio.ufms.br/handle/123456789/132 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo |
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