Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika

Detalhes bibliográficos
Autor(a) principal: Lopes, Anna Karolyne Kaimmi Lima e Souza
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFMT
Texto Completo: http://ri.ufmt.br/handle/1/4751
Resumo: Neuropsychomotor development (DNPM) is a multidimensional process and has the effect of making the child able to respond to their needs and to the environment. Any factor that disturbs the development can cause, to a greater or lesser degree, disorders of this process. The confirmation of the association of cases of microcephaly in Brazil with Zika virus infection (ZIKV) leads to the need for studies on the repercussion in DNPM due to central nervous system (CNS) impairment. Objective - to analyze the neuropsychomotor development of children exposed to congenital Zika virus infection in the city of Cuiabá. Methods - Cross-sectional observational study with children who were exposed to Zika virus during pregnancy. The children were evaluated between May and September 2018, using the Denver II test for screening for neuropsychomotor development. The information related to the mother, socioeconomic conditions of the family, prenatal, neonatal and postnatal diagnoses were obtained through interviews with the mothers and / or children's parents. Data were analyzed using the STATA version 12 statistical package. Descriptive analyzes were performed to verify the association between the independent variables and performance in the Denver II test (dependent variable). Fisher's exact test was used (p <0, 05). Results - The group consisted of 30 children, mostly aged between 12 and 24 months (60%) and males (63%). Of this total, 46.67% presented alterations in DNPM, with the greatest delays in the language areas (46.67%) and in the fine motor aspect (43.33%). The predominance of the infection occurred in the first and the second trimester of gestation. 70% of the children had z scores of the current weight between> -2 and <2, classified as adequate; 40% presented microcephaly at birth and 46.67% after the first month of life. Conclusions: Children exposed to ZIKV congenital infection presented delays in neuropsychomotor development, and the earlier an infection occurs during pregnancy, the greater will be the CNS concomitant to the DNPM. The illnesses become more evident as the child approaches the 24 months of age, when they did not have early professional accompaniment to stimulate the development, and in the poorest and poorly educated population extracts. It is important to emphasize the importance of public policies that allow children, as early as possible, the intervention of specialized multiprofessional team.
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spelling Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus ZikaGravidezZika vírusTranstornos do neurodesenvolvimentoCNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVAPregnancyZika virusNeurodevelopmental disordersNeuropsychomotor development (DNPM) is a multidimensional process and has the effect of making the child able to respond to their needs and to the environment. Any factor that disturbs the development can cause, to a greater or lesser degree, disorders of this process. The confirmation of the association of cases of microcephaly in Brazil with Zika virus infection (ZIKV) leads to the need for studies on the repercussion in DNPM due to central nervous system (CNS) impairment. Objective - to analyze the neuropsychomotor development of children exposed to congenital Zika virus infection in the city of Cuiabá. Methods - Cross-sectional observational study with children who were exposed to Zika virus during pregnancy. The children were evaluated between May and September 2018, using the Denver II test for screening for neuropsychomotor development. The information related to the mother, socioeconomic conditions of the family, prenatal, neonatal and postnatal diagnoses were obtained through interviews with the mothers and / or children's parents. Data were analyzed using the STATA version 12 statistical package. Descriptive analyzes were performed to verify the association between the independent variables and performance in the Denver II test (dependent variable). Fisher's exact test was used (p <0, 05). Results - The group consisted of 30 children, mostly aged between 12 and 24 months (60%) and males (63%). Of this total, 46.67% presented alterations in DNPM, with the greatest delays in the language areas (46.67%) and in the fine motor aspect (43.33%). The predominance of the infection occurred in the first and the second trimester of gestation. 70% of the children had z scores of the current weight between> -2 and <2, classified as adequate; 40% presented microcephaly at birth and 46.67% after the first month of life. Conclusions: Children exposed to ZIKV congenital infection presented delays in neuropsychomotor development, and the earlier an infection occurs during pregnancy, the greater will be the CNS concomitant to the DNPM. The illnesses become more evident as the child approaches the 24 months of age, when they did not have early professional accompaniment to stimulate the development, and in the poorest and poorly educated population extracts. It is important to emphasize the importance of public policies that allow children, as early as possible, the intervention of specialized multiprofessional team.O desenvolvimento neuropsicomotor (DNPM) é um processo multidimensional e tem como efeito tornar a criança capaz de responder às suas necessidades e às do meio ambiente. Qualquer fator que perturbe o desenvolvimento pode provocar com maior ou menor intensidade, transtornos desse processo. A comprovação da associação dos casos de microcefalia no Brasil com a infecção pelo vírus Zika (ZIKV), leva a necessidade de estudos sobre a repercussão no DNPM decorrentes do comprometimento do sistema nervoso central (SNC). Objetivo - Analisar o desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika atendidas no município de Cuiabá. Métodos - Estudo observacional, de corte transversal, com crianças que foram expostas ao vírus Zika durante a gestação. As crianças foram avaliadas entre maio e setembro de 2018, utilizando o teste de Denver II para triagem do desenvolvimento neuropsicomotor. As informações relacionadas à mãe, condições socioeconômicas da família, diagnósticos pré-natais, neonatais e pós-natais foram obtidas por entrevistas com as mães e/ou pais das crianças. Os dados foram analisados com o pacote estatístico STATA versão 12. Foram realizadas análises descritivas e para verificar a associação entre as variáveis independentes e desempenho no teste de Denver II (variável dependente), utilizou-se o teste exato de Fisher (p<0,05). Resultados – O grupo foi composto por 30 crianças, à maioria com idade entre 12 e 24 meses (60%) e do sexo masculino (63%). Desse total 46,67% apresentaram alterações no DNPM, sendo os maiores atrasos nas áreas da linguagem (46,67%) e no aspecto motor fino (43,33%). O predomínio da infecção ocorreu no primeiro e no início do segundo trimestre de gestação. 70% das crianças tinham escore-Z do peso atual entre > -2 e < 2, classificadas como adequadas; 40% apresentaram microcefalia ao nascimento e 46,67% após o 1o mês de vida. Conclusões - Crianças expostas à infecção congênita pelo ZIKV apresentaram atrasos no desenvolvimento neuropsicomotor, sendo que quanto mais precoce ocorrer à infecção na gestação, maiores serão os acometimentos para o SNC concomitantes ao DNPM. Os agravos tornam-se mais evidentes à medida que a criança se aproxima dos 24 meses de idade, quando não tiveram precocemente acompanhamento profissional para estímulo do desenvolvimento, e em extratos populacionais mais pobres e de baixa escolaridade. Ressalta-se a importância de políticas públicas que propiciem às crianças, o mais precoce possível, a intervenção de equipe multiprofissional especializada.Universidade Federal de Mato GrossoBrasilInstituto de Saúde Coletiva (ISC)UFMT CUC - CuiabáPrograma de Pós-Graduação em Saúde ColetivaTrettel, Ana Claudia Pereira TerçasAndrade, Amanda Cristina de Souzahttp://lattes.cnpq.br/2405137871559865http://lattes.cnpq.br/9144280121462086Trettel, Ana Claudia Pereira Terças704.996.401-87http://lattes.cnpq.br/9144280121462086Muraro, Ana Paula003.957.481-43http://lattes.cnpq.br/1256112467400959704.996.401-87076.194.226-25Nascimento, Vagner Ferreira do011.257.771-76http://lattes.cnpq.br/4134268880865735Lopes, Anna Karolyne Kaimmi Lima e Souza2023-10-11T15:00:33Z2019-12-172023-10-11T15:00:33Z2019-07-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisLOPES, Anna Karolyne Kaimmi Lima e Souza. Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika. 2019. 73 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2019.http://ri.ufmt.br/handle/1/4751porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMTinstname:Universidade Federal de Mato Grosso (UFMT)instacron:UFMT2023-10-18T07:01:17Zoai:localhost:1/4751Repositório InstitucionalPUBhttp://ri.ufmt.br/oai/requestjordanbiblio@gmail.comopendoar:2023-10-18T07:01:17Repositório Institucional da UFMT - Universidade Federal de Mato Grosso (UFMT)false
dc.title.none.fl_str_mv Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
title Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
spellingShingle Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
Lopes, Anna Karolyne Kaimmi Lima e Souza
Gravidez
Zika vírus
Transtornos do neurodesenvolvimento
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Pregnancy
Zika virus
Neurodevelopmental disorders
title_short Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
title_full Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
title_fullStr Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
title_full_unstemmed Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
title_sort Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika
author Lopes, Anna Karolyne Kaimmi Lima e Souza
author_facet Lopes, Anna Karolyne Kaimmi Lima e Souza
author_role author
dc.contributor.none.fl_str_mv Trettel, Ana Claudia Pereira Terças
Andrade, Amanda Cristina de Souza
http://lattes.cnpq.br/2405137871559865
http://lattes.cnpq.br/9144280121462086
Trettel, Ana Claudia Pereira Terças
704.996.401-87
http://lattes.cnpq.br/9144280121462086
Muraro, Ana Paula
003.957.481-43
http://lattes.cnpq.br/1256112467400959
704.996.401-87
076.194.226-25
Nascimento, Vagner Ferreira do
011.257.771-76
http://lattes.cnpq.br/4134268880865735
dc.contributor.author.fl_str_mv Lopes, Anna Karolyne Kaimmi Lima e Souza
dc.subject.por.fl_str_mv Gravidez
Zika vírus
Transtornos do neurodesenvolvimento
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Pregnancy
Zika virus
Neurodevelopmental disorders
topic Gravidez
Zika vírus
Transtornos do neurodesenvolvimento
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Pregnancy
Zika virus
Neurodevelopmental disorders
description Neuropsychomotor development (DNPM) is a multidimensional process and has the effect of making the child able to respond to their needs and to the environment. Any factor that disturbs the development can cause, to a greater or lesser degree, disorders of this process. The confirmation of the association of cases of microcephaly in Brazil with Zika virus infection (ZIKV) leads to the need for studies on the repercussion in DNPM due to central nervous system (CNS) impairment. Objective - to analyze the neuropsychomotor development of children exposed to congenital Zika virus infection in the city of Cuiabá. Methods - Cross-sectional observational study with children who were exposed to Zika virus during pregnancy. The children were evaluated between May and September 2018, using the Denver II test for screening for neuropsychomotor development. The information related to the mother, socioeconomic conditions of the family, prenatal, neonatal and postnatal diagnoses were obtained through interviews with the mothers and / or children's parents. Data were analyzed using the STATA version 12 statistical package. Descriptive analyzes were performed to verify the association between the independent variables and performance in the Denver II test (dependent variable). Fisher's exact test was used (p <0, 05). Results - The group consisted of 30 children, mostly aged between 12 and 24 months (60%) and males (63%). Of this total, 46.67% presented alterations in DNPM, with the greatest delays in the language areas (46.67%) and in the fine motor aspect (43.33%). The predominance of the infection occurred in the first and the second trimester of gestation. 70% of the children had z scores of the current weight between> -2 and <2, classified as adequate; 40% presented microcephaly at birth and 46.67% after the first month of life. Conclusions: Children exposed to ZIKV congenital infection presented delays in neuropsychomotor development, and the earlier an infection occurs during pregnancy, the greater will be the CNS concomitant to the DNPM. The illnesses become more evident as the child approaches the 24 months of age, when they did not have early professional accompaniment to stimulate the development, and in the poorest and poorly educated population extracts. It is important to emphasize the importance of public policies that allow children, as early as possible, the intervention of specialized multiprofessional team.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-17
2019-07-03
2023-10-11T15:00:33Z
2023-10-11T15:00:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv LOPES, Anna Karolyne Kaimmi Lima e Souza. Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika. 2019. 73 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2019.
http://ri.ufmt.br/handle/1/4751
identifier_str_mv LOPES, Anna Karolyne Kaimmi Lima e Souza. Desenvolvimento neuropsicomotor de crianças expostas à infecção congênita pelo vírus Zika. 2019. 73 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2019.
url http://ri.ufmt.br/handle/1/4751
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
publisher.none.fl_str_mv Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMT
instname:Universidade Federal de Mato Grosso (UFMT)
instacron:UFMT
instname_str Universidade Federal de Mato Grosso (UFMT)
instacron_str UFMT
institution UFMT
reponame_str Repositório Institucional da UFMT
collection Repositório Institucional da UFMT
repository.name.fl_str_mv Repositório Institucional da UFMT - Universidade Federal de Mato Grosso (UFMT)
repository.mail.fl_str_mv jordanbiblio@gmail.com
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